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Tyra G. Wolfsberg, Ph.D.
Associate Investigator, Genome Technology Branch
Associate Director, Bioinformatics and Scientific Programming Core
Selected Publications
Wolfsberg T.G., Gabrielian A.E., Campbell, M.J., Cho, R.J., Spouge, J.L., and Landsman D. Candidate regulatory sequence elements for cell cycle-dependent transcription in Saccharomyces cerevisiae. Genome Research, 9:775-792. 1999. [PubMed]
Wolfsberg T.G., Schafer S., Tatusov R.L., andTatusova T.A. Organelle genome resources at NCBI. Trends Biochem Sci, 26:199-203. 2001. [PubMed]
Wolfsberg, T.G., Wetterstrand, K.A., Guyer, M.S., Collins, F.S., and Baxevanis, A.D. A User's Guide to the Human Genome II. Nature Genetics: Supplement, 35: 1-79. 2003. [Full Text]
Crawford G.E., Holt I.E., Mullikin J.C., Tai D., Blakesley R., Bouffard G., Young A., Masiello C., Green E.D., Wolfsberg T.G., Collins F.S.; National Institutes Of Health Intramural Sequencing Center. Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites. Proc Natl Acad Sci U S A, 27;101(4):992-7. 2004. [PubMed]
ENCODE Project Consortium. The ENCODE (ENCyclopedia Of DNA Elements) project. Science 306:636-40, 2004. [PubMed]
Gillanders E.M., Masiello A., Gildea D., Umayam L., Duggal P., Jones M.P., Klein A.P., Freas-Lutz D., Ibay G., Trout K., Wolfsberg T.G., Trent J.M., Bailey-Wilson J.E., Baxevanis A.D. GeneLink: a database to facilitate genetic studies of complex traits. BMC Genomics 5:81-95, 2004. [PubMed]
Hematti P., Hong B.K., Ferguson C., Adler R., Hanawa H., Sellers S., Holt I.E., Eckfeldt C.E., Sharma Y., Schmidt M., von Kalle C., Persons D.A., Billings E.M., Verfaillie C.M., Nienhuis A.W., Wolfsberg T.G., Dunbar C.E., Calmels B. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells. PLoS Biol 2:e423, 2004. [PubMed]
Scacheri P.C., Rozenblatt-Rosen O., Caplen N.J., Wolfsberg T.G., Umayam L., Lee J.C., Hughes C.M., Shanmugam K.S., Bhattacharjee A., Meyerson M., Collins F.S. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci USA, 17;101(7):1892-7. 2004. [PubMed]
Crawford G.E., Holt I.E., Whittle J., Webb B.D., Tai D., Davis S., Margulies E.H., Chen Y., Bernat J.A., Ginsburg D., Zhou D., Luo S., Vasicek T.J., Daly M.J., Wolfsberg T.G., Collins F.S. Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res., 16(1):123-31. 2006. [PubMed]
Crawford GE, Davis S, Scacheri PC, Renaud G, Halawi MJ, Erdos MR, Green R, Meltzer PS, Wolfsberg TG, Collins FS. DNase-chip:
A high resolution method to identify DNAase I hypersensitive sites using tiled microarrays. Nature Methods, 3:503-509. 2006. [PubMed]
Baxter LL, Hsu BJ, Umayam L, Wolfsberg TG, Larson DM, Frith MC, Kawai J, Hayashizaki Y, Carninci P, Pavan WJ. Informatic and genomic analysis of melanocyte cDNA libraries as a resource for the study of melanocyte development and function. Pigment Cell Research, 20:201-209. 2007. [PubMed]
Elnitski LL, Shah P, Moreland RT, Umayam L, Wolfsberg TG, Baxevanis AB. The ENCODEdb portal: Simplified access to ENCODE consortium data. Genome Research, 17:954-959. 2007. [PubMed]
Pike BL, Greiner TC, Wang X, Weisenburger DD, Hsu YH, Renaud G, Wolfsberg TG, Kim M, Weisenberger DJ, Siegmund KD, Ye W, Groshen S, Mehrian-Shai R, Delabie J, Chan WC, Laird PW, Hacia JG. DNA methylation profiles in diffuse large B-cell lymphoma and their relationship to gene expression status. Leukemia, 1-9. 2008. [PubMed]
Book Chapters
White J.M., Bridges L.C., DeSimone D.W., Tomczuk M.: Introduction to the ADAM family: Wolfsberg T.G. In: N.M. Hooper and U. Lendeckel (eds.). In Proteases in Biology and Disease, pp. 1-28. Springer-Verlag New York, LLC. 2005.
Last Reviewed: April 29, 2009
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