HomeAbout NHGRIAbout the Office of the DirectorReports and Workshop Summaries from ODHereditary Hemorrhagic Telangiectasia: Vascular Biology and Pathophysiology HHT: Vascular Biology and Pathophysiology Workshop Agenda

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Wednesday, June 7, 2006 1:00 p.m. Optional Grant Writing / Training and Career Opportunities Workshop Thursday, July 8, 2003 8:00 a.m. Welcome: Francis Collins, Charles Peterson, Stephen Groft, Marianne Clancy 8:20 a.m. Keynote I: Overview of Transforming Growth Factor- β Pathway - Jeff Wrana 8:50 a.m. Keynote II: Transforming Growth Factor- β Pathway and HHT - Carmelo Bernabeu 9:10 a.m Platform Presentations: Transforming Growth Factor- β Pathway Identification and Characterization of Genetic Loci that Determine Mouse Strain-Specific Requirements for Tgfb1 during Developmental Angiogenesis - Rosemary Akhurst BMP9 Is a Potent Activator of ALK1 Signalling in Endothelial Cells - Sabine Bailly Smad-Independent Roles for Endoglin in Vascular Cell Function - Calvin Vary 10:15 a.m. Discussion: Transforming Growth Factor- β Pathway 10:45 a.m Keynote III: Overview of Vascular Biology - Marlene Rabinovitch 11:15 a.m. Keynote IV: Vascular Biology and HHT - Michelle Letarte 11:45 a.m. Platform Presentations: Vascular Biology Alk1 Activation Favors Resolution in the Zebrafish Endothelium - Beth Roman Endoglin Has a Crucial Role in Blood Cell-Mediated Vascular Repair - Linda van Laake 12:15 p.m. Discussion: Vascular Biology 1:30 p.m. Keynote V: Overview of Endothelial Biology - Luisa Iruela-Arispe 2:00 p.m. Keynote VI: Endothelial Biology and HHT - Duncan Stewart 2:30 p.m. Platform Presentations: Endothelial Biology Contribution of Endothelial O-Glycans to Vascular Development - Lijun Xia The Characterization of Endothelial Cells from Hereditary Haemorrhagic Telangiectasia Patients Reveals Abnormalities in Cytoskeleton and Tube Formation - Africa Fernandez-Lopez 3:00 p.m. Discussion: Endothelial Biology 3:30 p.m. Keynote VII: Overview of Chemical Genomics - Christopher Austin 4:00 p.m. Discussion: Chemical Genomics and HHT 4:30 p.m. Poster Session I (odd-numbered posters) 5:30 p.m. Poster Session II (even-numbered posters) Friday, June 9, 2006 7:00 a.m. Poster Viewing 8:00 a.m. Keynote VIII: Animal Models of Vascular Pathophysiology - Dean Li 8:30 a.m. Keynote IX: HHT Organ Pathophysiology in Humans - Marie Faughnan 9:00 a.m. Platform Presentations: Organ Pathophysiology In Vivo Assessment of the ALK1-ALK5 Balance for Mediating TGF-β Signal in Endothelium during Vascular Development in Mice - Paul Oh Abnormal Development of Retinal Vasculature and Retinal Neovascularization during Oxygen-Induced Ischemic Retinopathy in Endoglin Heterozygous Mice - Nader Sheibani 9:45 a.m. Discussion: Organ Pathophysiology 10:50 a.m. Concurrent Workshops Transforming Growth Factor- β Pathway Vascular Biology Endothelial Biology Organ Pathophysiology 1:45 p.m. Workshop Reports and Discussions 3:45 p.m. Summary and Future Directions

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Last Reviewed: January 12, 2009