Technology Description:
Agricultural Research Service scientists in Michigan have developed a way to produce specific antibodies that distinguish one protein from a set of very similar proteins. The antibodies produced are used to identify disease resistance traits in chickens. This method is the only way to produce antibody specific for a multi-gene complex involved in disease resistance. Other technologies exist, but they are less specific and require “blood typing” and DNA sequencing—which are more expensive and time consuming. This technology could be used to develop an ELISA test kit for detecting specific poultry viruses.
Poultry breeders and researchers could use this technology in their chicken breeding selection programs.
Reference: A copy of USPN 6,075,125 (Docket #0064.96), “Production of Specific Antisera Using Transfected Molecules; e.g., Major Histocompatibility Complex (MHC) Molecules in Chickens,” which issued on June 13, 2000, can be obtained from the U.S. Patent and Trademark Website at: www.uspto.gov. Foreign rights are not available.
Inventors:
Henry D. Hunt Avian Disease and Oncology Laboratory East Lansing, Michigan 48823-5338 Phone: (517) 337-6834 Fax: (517) 337-6776 hunthd@msu.edu |
Larry D. Bacon (retired) 3606 E. Mt. Hope Road East Lansing, MI 48823-5338 Phone: (517) 337-6831 Fax: (517) 337-6774
Janet E. Fulton (Formerly with ARS)
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