Technical Abstract: Molecularly imprinted polymers (MIPs) are a class of synthetic receptors capable of selective recognition of analytes. Recent developments in imprinting technology have made it possible to apply this technology in a range of applications, including mycotoxin detection. Structure-activity relationships between reported MIPs for ochratoxin A, deoxynivalenol and zearalenone are reviewed. In addition, results from a molecular imprinted solid phase extraction (MISPE) analysis of MIPs designed to recognize moniliformin show the binding properties of the moniliformin MIPS are influenced by solvent and matrix effects.