Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility

Release Date: September 2005

Summary of Recommendations / Supporting Documents

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Summary of Recommendations

• The U.S. Preventive Services Task Force (USPSTF) recommends against routine referral for genetic counseling or routine breast cancer susceptibility gene (BRCA) testing for women whose family history is not associated with an increased risk for deleterious mutations in breast cancer susceptibility gene 1 (BRCA1) or breast cancer susceptibility gene 2 (BRCA2).
  Grade: D Recommendation.
• The USPSTF recommends that women whose family history is associated with an increased risk for deleterious mutations in BRCA1 or BRCA2 genes be referred for genetic counseling and evaluation for BRCA testing.
  Grade: B Recommendation.

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Supporting Documents

Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility, September 2005
Recommendation Statement (PDF File, 220 KB; PDF Help)
Evidence Review (PDF File, 885 KB; PDF Help)
Evidence Synthesis (PDF File, 3.6 MB; PDF Help)

Top of Page

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Current as of September 2005

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Internet Citation:

Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility, Topic Page. September 2005. U.S. Preventive Services Task Force. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/clinic/uspstf/uspsbrgen.htm

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