Stage 0 (Carcinoma in Situ)
Stage I Esophageal Cancer
Stage II Esophageal Cancer
Stage III Esophageal Cancer
Stage IV Esophageal Cancer

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Treatment of stage 0 is usually surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage 0 esophageal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Treatment of stage I esophageal cancer may include the following:

• Surgery.
• Clinical trials.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage I esophageal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Treatment of stage II esophageal cancer may include the following:

• Surgery.
• Chemoradiation (treatment that combines chemotherapy with radiation therapy).
• Clinical trials of chemoradiation followed by surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage II esophageal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Treatment of stage III esophageal cancer may include the following:

• Surgery.
• Chemoradiation (treatment that combines chemotherapy with radiation therapy).
• Clinical trials of chemoradiation followed by surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage III esophageal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Treatment of stage IV esophageal cancer may include the following:

• An esophageal stent as palliative therapy to relieve symptoms and improve quality of life.
• External or internal radiation therapy as palliative therapy to relieve symptoms and improve quality of life.
• Laser surgery or electrocoagulation as palliative therapy to relieve symptoms and improve quality of life.
• Chemotherapy.
• Clinical trials of chemotherapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with stage IV esophageal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

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