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Research CentersEPA's Science To Achieve Results (STAR) Program Centers of Excellence in Children's Environmental Health and Disease Prevention Research
The long term goal of the Center for the
Asthmatic Child in the Urban Environment is to understand how exposures
to environmental pollutants and allergens may relate to airway inflammation
and respiratory morbidity in children with asthma living in the
inner city of Baltimore and to develop effective strategies to reduce
morbidity by The immediate goal of these studies is two-fold; we will test currently available recommendations for modifying environmental pollutant and indoor allergen exposures, and we will develop data that will allow us to create new strategies that may combine other interventions or target them at genetically susceptible hosts. Within the Center, the research projects will function in an integrated way, directed toward a single goal and holding frequent conferences to discuss our progress and to increase our understanding of relevant scientific progress in each component's field. At the same time, we will provide this same information to the Baltimore community and involve them in an ongoing dialog to evaluate our progress and plan our intervention efforts. Finally, we will have involved a large number of families in scientific studies of asthma and will have developed relationships that will allow trials of these newly developed interventions to be conducted efficiently. Our ultimate goal remains to develop the scientific understanding that will allow us to recommend effective intervention strategies. To accomplish these goals, we have created a multi-disciplinary program that includes both basic and applied research programs in combination with a community-based prevention research project. Center Abstract: Research Projects:
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Genetic Mechanisms of Susceptibility to Inhaled Pollutants