Mouse Genome Sequencing: Mus musculus
The National Human Genome Research Institute (NHGRI) and the Wellcome Trust currently support a mouse genome sequencing project that aims to produce a robust physical map, and a high quality, finished genomic sequence of the C57BL/6J strain of Mus musculus.
This project is led by the Mouse Genome Sequencing Consortium (MGSC), a collaboration consisting of four large sequencing centers: the Broad Institute/MIT Center for Genomic Research; the Washington University Genome Sequencing Center; the Wellcome Trust Sanger Institute; The Baylor college of Medicine Human Genome Sequencing Center; and an international database, Ensembl, a joint project between the European Bioinformatics Institute and the Sanger Centre.
Project Links:
Supporting Institutions
News regarding sequencing, assembly and annotation of the mouse genome can be found in the Mouse Genome Monthly
NHGRI has also convened a group of leading mouse researchers - the Mouse Sequencing Liaison Group - to serve as a line of communication between the sequencing centers and the funding agencies, and the mouse research community.
Membership of this Mouse Sequencing Liaison Group
Wayne Frankel, Chair - The Jackson Laboratory
Rudi Balling - Gesellschaft für Biotechnologische Forschung - GBF
Steve Brown - MRC Mouse Genome Centre
Maja Bucan - University of Pennsylvania
Sally Camper - University of Michigan
David Kingsley - Stanford University
Janet Rossant - Mt. Sinai Hospital, Toronto
Eddy Rubin - Lawrence Berkeley Laboratory
Joseph Takahashi - Northwestern University
The Trans-NIH Mouse Initiative [nih.gov] is a source of information for the development of a wide range of genomic and genetic resources related to the laboratory mouse.
For additional information about the Trans-NIH Mouse Initiative, please contact:
Dr. Bettie Graham
E-mail: Bettie_Graham@nih.gov
Additional Resources
Sequence and Assembly
- Individual Sequence Reads:
- Sequence Assemblies:
Model Organism Database
Mapping
Bacterial Artificial Chromosome (BAC) End Sequencing
ESTs
cDNAs
SNPs
- dbSNP [ncbi.nlm.nih.gov] - Database of Single Nucleotide Polymorphisms (SNPs) at NCBI
BAC Libraries
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Other Related Sites
Last Reviewed: October 29, 2008
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