Clinical Trials
Attention Deficit Hyperactivity Disorder (ADHD, ADD)
Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Effects of Using Betahistine to Treat Adults With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will determine whether the drug betahistine increases focus and causes side effects in people with attention deficit hyperactivity disorder. Ages 22-55. Location in Cincinnati, OH.
- Treatment of Severe Childhood Aggression (The TOSCA Study).
Interventional study. This study will determine the safety and effectiveness of two medications for treating aggression in children with attention deficit hyperactivity disorder (ADHD). Ages 6-12. Locations in Stony Brook, NY; Cleveland, OH; Columbus, OH; Pittsburgh, PA.
- Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study).
Interventional study. This study will determine the advantages and disadvantages of adding one of two different types of drugs to stimulant treatment for reducing aggressive behavior in children with attention deficit with hyperactivity disorder (ADHD). Ages 6-12. Locations in Glen Oaks, NY; Stony Brook, NY; San Antonio, TX.
- A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation.
Interventional study. Objective: To test the efficacy of citalopram plus methylphenidate vs. Ages 7-17. Location in Bethesda, MD.
- Effectiveness of an Extended Release Stimulant Medication in Treating Preschool Children With Attention Deficit Hyperactivity Disorder (The APS Study).
Interventional study. This study will evaluate the safety and effectiveness of extended release mixed amphetamine salts in treating preschool children with attention deficit hyperactivity disorder. Ages 36 Months-66 Months. Location in Springfield, MA.
- Atomoxetine and Parent Management Training in Treating Children With Autism and Symptoms of Attention Deficit Disorder With Hyperactivity.
Interventional study. This study will evaluate the effectiveness of the medication atomoxetine, with and without parent management training, in treating children with autism or pervasive developmental disorder not otherwise specified who have symptoms of attention deficit hyperactivity disorder. Ages 5-14. Locations in Rochester, NY; Columbus, OH; Pittsburgh, PA.
- Effectiveness of the Non-Stimulant Medication Lobeline in Improving Symptoms of Attention Deficit Hyperactivity Disorder in Adults.
Interventional study. The study will evaluate the effectiveness of the nonstimulant medication lobeline in improving symptoms of attention deficit hyperactivity disorder in adults. Ages 21-45. Location in Lexington, KY.
- Effectiveness of School- and Home-Based Mental Health Services in Improving Learning and Behavior in Children in Urban Schools.
Interventional study. This study will evaluate the effectiveness of school- and home-based mental health services and training modules in supporting learning and behavior in financially disadvantaged children who live in urban areas. Ages 5-12. Location in Chicago, IL.
- Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders.
Interventional study. This study will evaluate the effectiveness of a doctor-office collaborative care approach in treating children with disruptive behavior problems in the pediatric primary care setting. Ages 5-12. Location in Pittsburgh, PA.
- Comparison of Two Psychosocial Therapies for Treating Children With Oppositional-Defiant Disorder.
Interventional study. This study will evaluate the effectiveness of two different psychosocial therapies, parent management training and collaborative problem solving, in treating children with oppositional-defiant disorder. Ages 8-12. Location in Blacksburg, VA.
- Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will evaluate the effectiveness of a single drug versus a combination of drugs in treating attention deficit hyperactivity disorder in children. Ages 7-14. Location in Los Angeles, CA.
- Parent Training to Promote Early Identification and Treatment of Childhood Behavioral Disorders.
Interventional study. This study will evaluate the effectiveness of a parent training program in improving parenting skills and reducing behavioral symptoms in young children who are at risk for developing childhood behavior disorders. Ages 22 Months-38 Months. Locations in Dorchester, MA; Jamaica Plain, MA; Leominster, MA; Southboro, MA; Westford, MA; Westwood, MA; Wilmington, MA; Woburn, MA.
- PET Scanning of Adults With Attention Deficit Hyperactivity Disorder (ADHD).
Evaluation study. This study will explore the brain in men with and without attention deficit hyperactivity disorder (ADHD). Ages 18-55. Location in Bethesda, MD.
- Organizational Skills Training for Children With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will evaluate the effectiveness of organizational skills training in improving organizational, time management, and planning difficulties in children with attention deficit hyperactivity disorder. Ages 8-11. Locations in Durham, NC; New York, NY.
- Methylphenidate for Treating Attention Deficit Hyperactivity Disorder in Children With Both ADHD and Epilepsy.
Interventional study. This study will evaluate the safety and effectiveness of extended release methylphenidate (XR-MPH) in treating attention deficit hyperactivity disorder (ADHD) in children with both ADHD and epilepsy. Ages 6-18. Location in Boston, MA.
- Integrated Parent Training for Treating Depression in Mothers of Children With Attention Deficit Hyperactivity Disorder.
Interventional study. This study will determine the effectiveness of integrated parent training versus standard behavioral parent training in treating depression and stress in mothers of children with attention deficit hyperactivity disorder (ADHD). Ages 6 and over. Location in College Park, MD.
- Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children.
Interventional study. This study will determine the effectiveness of stimulant and nonstimulant medication in treating the symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents. Ages 6-17. Locations in Chicago, IL; New York City, NY.
- Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children.
Interventional study. This study will first examine the cognitive and behavioral differences in children who have an autism spectrum disorder (ASD) and who do and do not have additional symptoms of attention deficit hyperactivity disorder (ADHD). Ages 7-12. Location in Houston, TX.
- Improving Attention Deficit Hyperactivity Disorder Treatment Adherence and Outcome in Primary Care Settings.
Interventional study. This study will determine the effectiveness of educating pediatricians about attention deficit hyperactivity disorder treatment guidelines in improving child behavior and pediatricians' adherence to medication guidelines. Ages 6-11. Location in Chicago, IL.
- A Clinic-Based Prevention Program for Families of Depressed Mothers.
Interventional study. This study will assess the effectiveness of the "Keeping Families Strong" program (KFS) in avoiding or delaying the onset of psychiatric disorders among children with depressed mothers. Ages 8 and over. Location in Baltimore, MD.
- Brain Changes in Children and Adolescents With Behavioral Problems.
Evaluation study. This study will examine brain changes in children and adolescents with behavioral problems and compare them to children and adolescents without behavioral problems. Ages 8-17. Location in Bethesda, MD.