| Definition |
A long-lasting disease that slowly destroys bile ducts in the liver. Bile, a substance that helps digest fat, leaves the liver through these ducts. When the ducts are damaged, bile builds up and harms the liver. Over time, the disease can cause cirrhosis (scar tissue that replaces healthy tissue) and may cause the liver to stop working. Symptoms of primary biliary cirrhosis include itchy skin, fatigue, jaundice (yellowing of the eyes and skin), cholesterol deposits on the skin, bloating (fluid retention), and dry eyes or mouth. |