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2009
April
April 23, 2009: USDA and NIH Funded International Science Consortium Publishes Analysis of Domestic Cattle Genome Sequence
The U.S. Department of Agriculture and the National Institutes of Health announce that an international consortium of researchers has published the genome of domestic cattle, the first livestock mammal to have its genetic blueprint sequenced and analyzed. The landmark research will bolster efforts to produce better beef and dairy products and lead to a better understanding of the human genome.
April 20, 2009: Free Online Toolkit Provides Standard Measures for Genome and Population Studies
The National Human Genome Research Institute, part of the National Institutes of Health, announces the release of the first version of a free online toolkit aimed at standardizing measurements of research subjects' physical characteristics and environmental exposures. The tools will give researchers more power to compare data from multiple studies, accelerating efforts to understand the complex genetic and environmental factors that cause cancer, heart disease, depression and other common diseases.
April 16, 2009:
Researchers Discover New Genetic Variants Associated with Increased Risk of Stroke
Scientists identify a previously unknown connection between two genetic variants and an increased risk of stroke, providing strong evidence for the existence of specific genes that help explain the genetic component of stroke. The research was funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health and by several other NIH institutes and centers.
March
March 29, 2009:
Skin Cancer Study Uncovers New Tumor Suppressor Gene
National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. The finding is reported in the journal Nature Genetics as part of a systematic genetic analysis of a group of enzymes implicated in skin cancer and many other types of cancer.
March 12, 2009:
Researchers Devise New Way to Explore DNA
A team that includes researchers from the National Institutes of Health (NIH) — and from the National Human Genome Research Institute — has found a new way of detecting functional regions in the human genome. The novel approach involves looking at the three-dimensional shape of the genome's DNA and not just reading the sequence of the four-letter alphabet of its DNA bases.
March 2, 2009: Low Levels of Vitamin B12 May Increase Risk for Neural Tube Defects
Children born to women who have low blood levels of vitamin B12 shortly before and after conception may have an increased risk of a neural tube defect, according to an analysis by researchers at the National Institutes of Health, Trinity College Dublin, and the Health Research Board of Ireland. Women with the lowest B12 levels had 5 times the risk of having a child with a neural tube defect compared to women with the highest B12 levels.
February
February 18, 2009: Could Genetics Improve Warfarin Dosing?
In a large-scale study and an upcoming clinical trial, scientists supported by the National Institutes of Health address one of the trickiest issues in prescribing medicine — how to quickly optimize each patient's dosage of the common blood-thinning drug warfarin. Using information from thousands of genetically and geographically diverse patients, an international team of researchers, funded in part by the National Human Genome Research Institute, has developed a way to use genetic information from patients that could help doctors better determine optimal warfarin doses. The results of the analysis are published in an article titled "Warfarin Dosing Using Clinical and Pharmacogenetic Data" in the Feb. 19 issue of The New England Journal of Medicine.
February 2, 2009: New Findings Raise Questions About Process Used to Identify Experimental Drug for Rare Genetic Diseases
A study by National Institutes of Health (NIH) researchers reveals surprising new insights into the process used to initially identify an experimental drug now being tested in people with cystic fibrosis and muscular dystrophy. Researchers emphasized that the clinical implications of their findings are unclear, but said the results suggest more work may be needed to make sure the screening process to select promising agents was not flawed by its effects on a firefly enzyme used as a marker.
Last Updated: April 16, 2009
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