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Vaccines
 Understanding
  What Is a Vaccine?
  Vaccine Benefits
  How Vaccines Work
  Adjuvants and Other Vaccine Ingredients
  Types of Vaccines
 Research


Vaccines

Vaccine Benefits

Once your immune system is trained to resist a disease, you are said to be immune to it. Before vaccines, the only way to become immune to a disease was to actually get it and, with luck, survive it. This is called naturally acquired immunity. With naturally acquired immunity, you suffer the symptoms of the disease and also risk the complications, which can be quite serious or even deadly. In addition, during certain stages of the illness, you may be contagious and pass the disease to family members, friends, or others who come into contact with you.

The Impact of Vaccines in the United States

Disease Baseline 20th Century Annual Cases 2006 Cases Percent Decrease
Measles 503,282 55 99.9%
Diphtheria 175,885 0 100%
Mumps 152,209 6,584 95.7%
Pertussis 147,271 15,632 89.4%
Smallpox 48,164 0 100%
Rubella 47,745 11 99.9%
Haemophilus influenzae type b, invasive 20,000 29 99.9%
Polio 16,316 0 100%
Tetanus 1,314 41 96.9%
Widespread use of vaccines in the United States has eliminated or almost eliminated infectious diseases that were once terrifying household names. Credit: Morbidity and Mortality Weekly Report, Centers for Disease Control and Prevention, 4/2/99, 3/21/08

Vaccines, which provide artificially acquired immunity, are an easier and less risky way to become immune. Vaccines can prevent a disease from occurring in the first place, rather than attempt to cure it after the fact.

Benefits for You and Others

It is also much cheaper to prevent a disease than to treat it. In a 2005 study on the economic impact of routine childhood immunization in the United States, researchers estimated that for every dollar spent, the vaccination program saved more than $5 in direct costs and approximately $11 in additional costs to society.

Vaccines protect not only yourself but also others around you. If your vaccine-primed immune system stops an illness before it starts, you will be contagious for a much shorter period of time, or perhaps not at all. Similarly, when other people are vaccinated, they are less likely to give the disease to you. Vaccines protect not only individuals but entire communities. That is why vaccines are vital to the public health goal of preventing diseases.

If a critical number of people within a community are vaccinated against a particular illness, the entire group becomes less likely to get the disease. This protection is called community, or herd, immunity. On the other hand, if too many people in a community do not get vaccinations, diseases can reappear. In 1989, low vaccination rates allowed a measles outbreak to occur in the United States. The outbreak resulted in more than 55,000 cases of measles and 136 measles-associated deaths.

Reference

F Zhou et al. Economic Evaluation of the 7-Vaccine Routine Childhood Immunization Schedule in the United States (Non-Government), 2001. Arch Pediatr Adolesc Med. 2005 Dec;159(12):1136-44.

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See Also

  • Vaccine Research Center
  • NIAID Lab Developing Intranasal RSV Vaccines
  • NIAID-Discovered Vaccine Used Worldwide Against Hepatitis A
  • NIAID Scientists Use Reverse Genetics to Develop Potential Dengue Vaccine
  • The Jordan Report: Accelerated Development of Vaccines 2007 (PDF)
  • Related Links

    View a list of links for more information about vaccines.

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    See Also

  • Vaccine Research Center
  • NIAID Lab Developing Intranasal RSV Vaccines
  • NIAID-Discovered Vaccine Used Worldwide Against Hepatitis A
  • NIAID Scientists Use Reverse Genetics to Develop Potential Dengue Vaccine
  • The Jordan Report: Accelerated Development of Vaccines 2007 (PDF)
  • Related Links

    View a list of links for more information about vaccines.