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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Molecular Biology 2008, 9 :109
Chromatin boundary proteins protect genes from transcriptional interactions and this insulator activity can be screened for in the Drosophila S2 cell line, using a new assay that complements existing in vivo methods.
BMC Molecular Biology 2008, 9 :105
A new conserved sequence motif found upstream of several microRNAs in two species of nematode worm, and also upstream of two microRNAs in mice and humans, may play a role in microRNA sequence recognition or regulation.
BMC Molecular Biology 2008, 9 :104
The APOBEC3 gene family, which blocks retrovirus replication, expanded in primates relative to artiodactyls via a series of dynamic recombination events, displaying this family's impressive functional modularity.
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Research article
TCF/beta-catenin plays an important role in HCCR-1 oncogene expression Gwang-won Cho, Mi Kim, Seung Kim, Seon Ha, Hyun Kim, Sanghee Kim, Jin W Kim BMC Molecular Biology 2009, 10 :42 (12 [Abstract ] [Provisional PDF ]
Research article
Chibby forms a homodimer through a heptad repeat of leucine residues in its C-terminal coiled-coil motif Adaobi Mofunanya, Feng-Qian Li, Jen-Chih Hsieh, Ken-Ichi Takemaru BMC Molecular Biology 2009, 10 :41 (12 [Abstract ] [Provisional PDF ]
Research article
Thrombin induces Egr-1 expression in fibroblasts involving elevation of the intracellular Ca2+ concentration, phosphorylation of ERK and activation of ternary complex factor Oliver G Rossler, Gerald Thiel BMC Molecular Biology 2009, 10 :40 (11 [Abstract ] [Provisional PDF ]
Research article
Revised Mimivirus major capsid protein sequence reveals intron-containing gene structure and extra domain Said Azza, Christian Cambillau, Didier Raoult, Marie Suzan-Monti BMC Molecular Biology 2009, 10 :39 (11 [Abstract ] [Provisional PDF ]
Research article
Characterization of the TRBP domain required for Dicer interaction and function in RNA interference Sylvanne M Daniels, Carlos E Melendez-Pena, Robert J Scarborough, Aicha Daher, Helen S Christensen, Mohamed El Far, Damian F Purcell, Sebastien Laine, Anne Gatignol BMC Molecular Biology 2009, 10 :38 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Human sex hormone-binding globulin gene expression- multiple promoters and complex alternative splicing Atif M Nakhla, Daniel J Hryb, William Rosner, Nicholas A Romas, Zhaoying Xiang, Scott M Kahn BMC Molecular Biology 2009, 10 :37 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Proteins of the origin recognition complex (ORC) and DNA topoisomerases on mammalian chromatin Hong-gang Hu, Martina Baack, Rolf Knippers BMC Molecular Biology 2009, 10 :36 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Liver-enriched transcription factors are critical for the expression of hepatocyte marker genes in mES-derived hepatocyte-lineage cells Pakpoom Kheolamai, Alan J Dickson BMC Molecular Biology 2009, 10 :35 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Use of the lambda Red-recombineering method for genetic engineering of Pantoea ananatis. Joanna I Katashkina, Yoshihiko Hara, Lyubov I Golubeva, Irina G Andreeva, Tatiana M Kuvaeva, Sergey V Mashko BMC Molecular Biology 2009, 10 :34 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The zinc finger protein Zn72D and DEAD box helicase Belle interact and control maleless mRNA and protein levels Kathleen A Worringer, Feixia Chu, Barbara Panning BMC Molecular Biology 2009, 10 :33 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Development-dependent changes in the tight DNA-protein complexes of barley on chromosome and gene level Tatjana Sjakste, Kristina Bielskiene, Marion Roder, Olga Sugoka, Danute Labeikyte, Lida Bagdoniene, Benediktas Juodka, Yegor Vassetzky, Nikolajs Sjakste BMC Plant Biology 2009, 9 :56 (12 [Abstract ] [Provisional PDF ]
Research article
Identification, distribution and molecular evolution of the pacifastin gene family in Metazoa Bert Breugelmans, Gert Simonet, Vincent van Hoef, Sofie Van Soest, Jozef Vanden Broeck BMC Evolutionary Biology 2009, 9 :97 (12 [Abstract ] [Provisional PDF ]
Research article
Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration S Jane Millward-Sadler, Patrick W Costello, Anthony J Freemont, Judith A Hoyland Arthritis Research & Therapy 2009, 11 :R65 (12 [Abstract ] [Provisional PDF ]
Research
Synergistic effect of human CycT1 and CRM1 on HIV-1 propagation in rat T cells and macrophages Hiroyuki Okada, Xianfeng Zhang, Ismael Ben Fofana, Mika Nagai, Hajime Suzuki, Takashi Ohashi, Hisatoshi Shida Retrovirology 2009, 6 :43 (12 [Abstract ] [Provisional PDF ]
Research
Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion. Satish B Cheepala, Weihong Yin, Zanobia Syed, Jennifer N Gill, Alaina McMillian, Heather E Kleiner, Mark Lynch, Raja Loganantharaj, Marjan Trutschl, Urska Cvek, John L Clifford Molecular Cancer 2009, 8 :27 (11 [Abstract ] [Provisional PDF ]
Research article
MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer Wenqing Qi, Larry Cooke, Amy Stejskal, Christopher J Riley, Kimiko Della Croce, Jose W Saldanha, David Bearss, Daruka Mahadevan BMC Cancer 2009, 9 :142 (11 [Abstract ] [Provisional PDF ]
Research
Binding characteristics of the ovine membrane progesterone receptor alpha and expression of the receptor during the estrous cycle Ryan L Ashley, J ALEJANDRO Arreguin-Arevalo, Terry M Nett Reproductive Biology and Endocrinology 2009, 7 :42 (11 [Abstract ] [Provisional PDF ]
Methodology article
Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi Dan Xu, Cecilia PEREZ Brandan, Miguel ANGEL Basombrio, Rick L Tarleton BMC Microbiology 2009, 9 :90 (11 [Abstract ] [Provisional PDF ]
Research article
Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis Joon-Woo Ahn, Brian J Atwell, Thomas H Roberts BMC Plant Biology 2009, 9 :52 (11 [Abstract ] [Provisional PDF ]
Review
Crk and CrkL adaptor proteins: networks for physiological and pathological signaling Raymond B Birge, Charalampos Kalodimos, Fuyuhiko Inagaki, Shinya Tanaka Cell Communication and Signaling 2009, 7 :13 (10 [Abstract ] [Provisional PDF ]
Featured articles 
