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BMC Clinical Pharmacology

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Editor-in-Chief
Melissa Norton, MD

Medical Editor
Jigisha Patel, MRCP PhD

In-house Editor
Scott Edmunds


Welcome to BMC Clinical Pharmacology published by BioMed Central
BMC Clinical Pharmacology is an open access journal publishing original peer-reviewed research articles in all aspects of clinical pharmacology. BMC Clinical Pharmacology (ISSN 1472-6904) is indexed/tracked/covered by PubMed, MEDLINE, CAS, Scopus, EMBASE and Google Scholar.



BMC Featured articles

Credit: Jupiter Images
BMC Clinical Pharmacology 2009, 9:6
Simvastatin treatment for patients at high risk of cardiovascular events or with diabetes results in only a minor increase in the risk of myopathy and hepatobiliary diseases over 5 years of use.
Jupiter Images
BMC Clinical Pharmacology 2009, 9:5
Six years after a large methanol poisoning outbreak in Estonia, the majority of victims still suffer from neurological impairments and visual complications, suggesting that irreversible damage has been caused by methanol consumption.
CSF crystal structure, source Wikipedia
BMC Clinical Pharmacology 2009, 9:2
A new, egg white-derived, recombinant glycosylated colony stimulating factor is equally safe and has similar pharmacokinetic and pharmacological properties to the first commercially available colony stimulating factor when tested on healthy individuals.


BMC  Latest articles published in BMC Clinical Pharmacology        [more info]


Research article
The frequency of adverse drug reaction related admissions according to method of detection, admission urgency and medical department specialty
Miran Brvar, Nina Fokter, Matjaz Bunc, Martin Mozina
BMC Clinical Pharmacology 2009, 9:8 (4May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Fatal drug poisonings in a Swedish general population
Anna K Jnsson, Olav Spigset, Micaela Tjderborn, Henrik Druid, Staffan Hgg
BMC Clinical Pharmacology 2009, 9:7 (27April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Effects of simvastatin 40 mg daily on muscle and liver adverse effects in a 5-year randomized placebo-controlled trial in 20,536 high-risk people
MRC/BHF Heart Protection Study Collaborative Group
BMC Clinical Pharmacology 2009, 9:6 (31March2009)
[Abstract] [Full text] [PDF]

Research article
Methanol poisoning and long term sequelae a six years follow-up after a large methanol outbreak
Raido Paasma, Knut Erik Hovda, Dag Jacobsen
BMC Clinical Pharmacology 2009, 9:5 (27March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Information about ADRs explored by pharmacovigilance approaches: a qualitative review of studies on antibiotics, SSRIs and NSAIDs
Lise Aagaard, Ebba Holme Hansen
BMC Clinical Pharmacology 2009, 9:4 (3March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series
Darren M Roberts, Renate Heilmair, Nick A Buckley, Andrew H Dawson, Mohamed Fahim, Michael Eddleston, Peter Eyer
BMC Clinical Pharmacology 2009, 9:3 (16February2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A glycosylated recombinant human granulocyte colony stimulating factor produced in a novel protein production system (AVI-014) in healthy subjects: a first-in human, single dose, controlled study
Roslyn Varki, Ed Pequignot, Mark C Leavitt, Andres Ferber, Walter K Kraft
BMC Clinical Pharmacology 2009, 9:2 (28January2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics
Andres F Zuluaga, Maria Agudelo, Carlos A Rodriguez, Omar Vesga
BMC Clinical Pharmacology 2009, 9:1 (16January2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin
MA Karsdal, I Byrjalsen, BJ Riis, C Christiansen
BMC Clinical Pharmacology 2008, 8:12 (4December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Systematic review of dexketoprofen in acute and chronic pain
R Andrew Moore, Jodie Barden
BMC Clinical Pharmacology 2008, 8:11 (31October2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
ALA-D activity is a reliable marker for oxidative stress in bone marrow transplantation patients
Thissiane L Goncalves, Dalila M Benvegnu, Gabriela Bonfanti, Andressa V Frediani, Joao Batista T Rocha
BMC Cancer 2009, 9:138 (8May2009)
[Abstract] [Provisional PDF]

Research
Opioids switching with transdermal systems in chronic cancer pain
Caterina Aurilio, Maria C. Pace, Vincenzo Pota, Pasquale Sansone, Manlio Barbarisi, Elisa Grella, Maria B. Passavanti
Journal of Experimental & Clinical Cancer Research 2009, 28:61 (7May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Original clinical investigation
Comparison of VerifyNow-P2Y12 test and Flow Cytometry for monitoring individual platelet response to clopidogrel. What is the cut-off value for identifying patients who are low responders to clopidogrel therapy?
Cosmo Godino, Loredana Mendolicchio, Filippo Figini, Azeem Latib, Andrew SP Sharp, John Cosgrave, Giliola Calori, Michela Cera, Alaide Chieffo, Alfredo Castelli, Attilio Maseri, Zaverio M Ruggeri, Antonio Colombo
Thrombosis Journal 2009, 7:4 (6May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy: a comparative study on traditional antiepileptic drugs versus oxcarbazepine
Marta Maschio, Loredana Dinapoli, Bruno Jandolo, Antonello Vidiri, Andrea Pace, Alessandra Fabi, Alfredo Pompili, Carmine M Carapella
Journal of Experimental & Clinical Cancer Research 2009, 28:60 (6May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Study protocol
Protocol for the PINCER trial: a cluster randomised trial comparing the effectiveness of a pharmacist-led IT-based intervention with simple feedback in reducing rates of clinically important errors in medicines management in general practices
Anthony J Avery, Sarah Rodgers, Judith A Cantrill, Sarah Armstrong, Rachel Elliott, Rachel Howard, Denise Kendrick, Caroline J Morris, Scott A Murray, Robin J Prescott, Kathrin Beyer, Aziz Sheikh
Trials 2009, 10:28 (1May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
Design, analysis, and presentation of crossover trials
Edward J Mills, An-Wen Chan, Ping Wu, Andy Vail, Gordon H Guyatt, Douglas G Altman
Trials 2009, 10:27 (30April2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro
Karen A Sutherland, Helena L Rogers, Denise Tosh, Michael J Rogers
Arthritis Research & Therapy 2009, 11:R58 (30April2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Review
Dissecting complex traits: recent advances in hypertension genomics
Kevin M O'Shaughnessy
Genome Med 2009, 1:43 (28April2009)
[Abstract] [Full text] [PDF]

Research
Pattern of benzodiazepine use in psychiatric outpatients in Pakistan: a cross-sectional survey
Syed Ahmer, Sumera Salamat, Rashid A M Khan, Saleem P Iqbal, Imran I Haider, Ayesha S Khan, Mohsan Zafar
Clinical Practice and Epidemiology in Mental Health 2009, 5:9 (28April2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Short paper
Nicotine-induced brain metabolism associated with anger provocation
Jean-G Gehricke, Steven G Potkin, Frances M Leslie, Sandra E Loughlin, Carol K Whalen, Larry D Jamner, James Mbogori, James H Fallon
Behavioral and Brain Functions 2009, 5:19 (24April2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

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