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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good
Welcome to BMC Biotechnology published by BioMed Central
BMC Biotechnology is an open access journal publishing original peer-reviewed research articles in the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.
BMC Biotechnology (ISSN 1472-6750) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Biotechnology 2009, 9 :22
The efficient production of biologically-active murine and viral Interleukin-10 (IL-10) in transgenic tobacco paves the way for oral administration of this anti-inflammatory cytokine in animal studies of autoimmune disease.
BMC Biotechnology 2009, 9 :16
Trait purity of seeds is key to crop improvement and a novel real-time qPCR-based method enables detection of wild-type contamination in Roundup Ready (glyphosate tolerant) soybean sequence, with potential for use in bulk screening.
BMC Biotechnology 2008, 8 :93
The dynamics of gene expression in fruitflies can be accurately tracked during fly movement by recording green fluorescent protein with multiple cameras, making it possible to correlate complex behavior and gene activity.
more info ]
Methodology article
Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins Antoine W Caron, Claire Nicolas, Bruno Gaillet, Ismaila Ba, Maxime Pinard, Alain Garnier, Bernard Massie, Renald Gilbert BMC Biotechnology 2009, 9 :42 (11 [Abstract ] [Provisional PDF ]
Research article
A suite of recombinant luminescent bacterial strains for the quantification of bioavailable heavy metals and toxicity testing Angela Ivask, Taisia Rolova, Anne Kahru BMC Biotechnology 2009, 9 :41 (8 [Abstract ] [Provisional PDF ]
Research article
Efficient CPP-mediated Cre protein delivery to developing and adult CNS tissues Yorick Gitton, Lorenzo Tibaldi, Edmond Dupont, Giovanni Levi, Alain Joliot BMC Biotechnology 2009, 9 :40 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks Mar BMC Biotechnology 2009, 9 :39 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Acetylation of PAMAM dendrimers for cellular delivery of siRNA Carolyn L Waite, Sarah M Sparks, Kathryn E Uhrich, Charles M Roth BMC Biotechnology 2009, 9 :38 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer Amy Raymond, Scott Lovell, Don Lorimer, John Walchli, Mark Mixon, Ellen Wallace, Kaitlin Thompkins, Kimberly Archer, Alex Burgin, Lance Stewart BMC Biotechnology 2009, 9 :37 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Software
Gene Composer: database software for protein construct design, codon engineering, and gene synthesis Don Lorimer, Amy Raymond, John Walchli, Mark Mixon, Adrienne Barrow, Ellen Wallace, Rena Grice, Alex Burgin, Lance Stewart BMC Biotechnology 2009, 9 :36 (21 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repair Xavier Leclerc, Olivier Danos, Daniel Scherman, Antoine Kichler BMC Biotechnology 2009, 9 :35 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Collagen matrices from sponge to nano: new perspectives for tissue engineering of skeletal muscle Justus P Beier, Dorothee Klumpp, Markus Rudisile, Roland Dersch, Joachim H Wendorff, Oliver Bleiziffer, Andreas Arkudas, Elias Polykandriotis, Raymund E Horch, Ulrich Kneser BMC Biotechnology 2009, 9 :34 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function Henry Daniell, Gricel Ruiz, Bela Denes, Laurence Sandberg, William Langridge BMC Biotechnology 2009, 9 :33 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems Lan K Nguyen, Don Kulasiri BMC Systems Biology 2009, 3 :51 (11 [Abstract ] [Provisional PDF ]
Methodology article
Robust MS quantification method for phospho-peptides using 18O/16O labeling Claus A. Andersen, Stefano Gotta, Letizia Magnoni, Roberto Raggiaschi, Andreas Kremer, Georg C. Terstappen BMC Bioinformatics 2009, 10 :141 (11 [Abstract ] [Provisional PDF ]
Methodology
Assessment of methods and analysis of outcomes for comprehensive optimization of nucleofection. Christopher Bradburne, Kelly Robertson, Dzung Thach Genetic Vaccines and Therapy 2009, 7 :6 (11 [Abstract ] [Provisional PDF ]
Research article
beta-catenin and transforming growth factor beta have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction. Raymond Poon, Saeid Amini Nik, Jessica Ahn, Laura Slade, Benjamin A Alman BMC Cell Biology 2009, 10 :38 (11 [Abstract ] [Provisional PDF ]
Research article
A probable aculeacin A acylase from the Ralstonia solanacearum GMI1000 is N-acyl-homoserine lactone acylase with quorum-quenching activity Chin-Nung Chen, Chii-Jaan Chen, Chen-Ting Liao, Chia-Yin Lee BMC Microbiology 2009, 9 :89 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Evaluation of the passage of Lactobacillus gasseri K7 and bifidobacteria from the stomach to intestines using a single reactor model Philipp Ritter, Christian Kohler, Ueli von Ah BMC Microbiology 2009, 9 :87 (8 [Abstract ] [Provisional PDF ]
Letters to the Editor
Mapping the moral boundaries of biological engineering Zachary N Russ Journal of Biological Engineering 2009, 3 :7 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Immunotherapy: rAAV2 expressing interleukin-15 inhibits HeLa cell tumor growth in mice
Giou-Teng Yiang, Horng-Jyh Harn, Yung-Luen Yu, Sheng-Chuan Hu, Yu-Ting Hung, Chia-Jung Hsieh, Shinn-Zong Lin, Chyou-Wei Wei Journal of Biomedical Science 2009, 16 :47 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of neutral biochemical network models
from time series data
Marco Vilela, Susana Vinga, Marco A Grivet Mattoso Maia, Eberhard O Voit, Jonas S Almeida BMC Systems Biology 2009, 3 :47 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae Oskar Bengtsson, Barbel Hahn-Hagerdal, Marie F Gorwa-Grauslund Biotechnology for Biofuels 2009, 2 :9 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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a Moreno-Villanueva, Ragen Pfeiffer, Thilo Sindlinger, Alan Leake, Marcus M
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