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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Maria Kowalczuk
Welcome to BMC Biology published by BioMed Central
BMC Biology - the flagship biology journal of the BMC series - publishes research and methodology articles of special importance and broad interest in any area of biology and biomedical sciences. BMC Biology (ISSN 1741-7007) is covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
BMC Biology 2009, 7 :22
Bacterial killing by an antimicrobial peptide has been monitored at the single-molecule level revealing four successive steps of the bactericidal process: binding, peptide association, membrane disruption and lysis of the cell.
BMC Biology 2009, 7 :20
Ros and Hurst comment on the recent study showing that laterally acquired genes are highly expressed in their recipient host, and discuss the evolutionary importance of lateral gene transfer.
BMC Biology 2009, 7 :19
Premature release of sperm from the Drosophila testis is prevented by F-actin and other cytoskeleton components, which together maintain developing spermatids in tight bundles within the head cyst cells in a mechanism resembling mammalian spermiation.
BMC Biology 2009, 7 :18
When two cotton genomes are merged, gene expression levels are not additive as they appear, instead allelic analysis shows expression is determined by parental dominance such that the prevailing parent differs gene by gene.
BMC Biology 2009, 7 :17
A heterologous cell system recapitulates the regulation of parathyroid hormone mRNA by the calcium-sensing receptor, an aspect of calcium homestasis mediated by the parathyroid gland in vivo, but not previously replicated in a cell culture model.
Latest articles published in BMC Biology [more info ]
Research article
Single molecule resolution of the antimicrobial action of quantum dot-labeled sushi peptide on live bacteria Sebastian Leptihn, Jia Yi Har, Jianzhu Chen, Bow Ho, Thorsten Wohland, Jeak Ling Ding BMC Biology 2009, 7 :22 (11 May 2009) [Abstract ] [Provisional PDF ]
Research article
Specific retention of the protostome-specific PsGEF may parallel with the evolution of mushroom bodies in insect and lophotrochozoan brains Nozomu Higuchi, Keigo Kohno, Tatsuhiko Kadowaki BMC Biology 2009, 7 :21 (7 May 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Commentary
Lateral gene transfer between prokaryotes and multicellular eukaryotes: ongoing and significant? Vera ID Ros, Gregory DD Hurst BMC Biology 2009, 7 :20 (5 May 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
F-actin-based extensions of the head cyst cell adhere to the maturing spermatids to maintain them in a tight bundle and prevent their premature release in Drosophila testis Bela S Desai, Seema Shirolikar, Krishanu Ray BMC Biology 2009, 7 :19 (5 May 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Genomic expression dominance in allopolyploids Ryan A Rapp, Joshua A Udall, Jonathan F Wendel BMC Biology 2009, 7 :18 (1 May 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells Hillel Galitzer, Vardit Lavi-Moshayoff, Morris Nechama, Tomer Meir, Justin Silver, Tally Naveh-Many BMC Biology 2009, 7 :17 (27 April 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Immunomodulatory parasites and toll-like receptor-mediated tumour necrosis factor alpha responsiveness in wild mammals Joseph A Jackson, Ida M Friberg, Luke Bolch, Ann Lowe, Catriona Ralli, Philip D Harris, Jerzy M Behnke, Janette E Bradley BMC Biology 2009, 7 :16 (22 April 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Remarkable convergent evolution in specialized parasitic Thecostraca (Crustacea) Marcos P rez-Losada, Jens T H eg, Keith A Crandall BMC Biology 2009, 7 :15 (17 April 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Defining behavioral and molecular differences between summer and migratory monarch butterflies Haisun Zhu, Robert J Gegear, Amy Casselman, Sriramana Kanginakudru, Steven M Reppert BMC Biology 2009, 7 :14 (31 March 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The relative ages of ectomycorrhizal mushrooms and their plant hosts estimated using Bayesian relaxed molecular clock analyses David S Hibbett, P Brandon Matheny BMC Biology 2009, 7 :13 (10 March 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Latest selected articles from BMC Medicine
This list contains articles from BMC Medicine that may be of interest to readers of BMC Biology
Research article
Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy Caterina Millino, Marina Fanin, Andrea Vettori, Paolo Laveder, Maria Luisa Mostacciuolo, Corrado Angelini, Gerolamo Lanfranchi BMC Medicine 2009, 7 :14 (7 April 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Intradermal influenza vaccination of healthy adults using a new microinjection system: a 3-year randomised controlled safety and immunogenicity trial Jiri Beran, Arvydas Ambrozaitis, Alvydas Laiskonis, Narseta Mickuviene, Patrick Bacart, Yvan Calozet, Etienne Demanet, Stephane Heijmans, Paul Van Belle, Fran oise Weber, Camille Salamand BMC Medicine 2009, 7 :13 (2 April 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A compact VEGF signature associated with distant metastases and poor outcomes Zhiyuan Hu, Cheng Fan, Chad Livasy, Xiaping He, Daniel S Oh, Matthew G Ewend, Lisa A Carey, Subbaya Subramanian, Robert West, Francis Ikpatt, Olufunmilayo I Olopade, Matt van de Rijn, Charles M Perou BMC Medicine 2009, 7 :9 (16 March 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Lack of utility of risk score and gynecological examination for screening for sexually transmitted infections in sexually active adolescents Eleuse MB Guimar es, Mark DC Guimar es, Maria Aparecida S Vieira, N dia M Bontempo, Mirian SS Seixas, M nica SD Garcia, Lyana ES Daud, Rejane LM C rtes, Maria de F tima C Alves BMC Medicine 2009, 7 :8 (11 March 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical A42 reduces their differentiation potential Markus Uhrig, Peter Brechlin, Olaf Jahn, Yuri Knyazev, Annette Weninger, Laura Busia, Kamran Honarnejad, Markus Otto, Tobias Hartmann BMC Medicine 2008, 6 :38 (16 December 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study Jeanne C Latourelle, Mei Sun, Mark F Lew, Oksana Suchowersky, Christine Klein, Lawrence I Golbe, Margery H Mark, John H Growdon, G Frederick Wooten, Ray L Watts, Mark Guttman, Brad A Racette, Joel S Perlmutter, Anwar Ahmed, Holly A Shill, Carlos Singer, Stefano Goldwurm, Gianni Pezzoli, Michela Zini, Marie H Saint-Hilaire, Audrey E Hendricks, Sally Williamson, Michael W Nagle, Jemma B Wilk, Tiffany Massood, Karen W Huskey, Jason M Laramie, Anita L DeStefano, Kenneth B Baker, Ilia Itin, et al. BMC Medicine 2008, 6 :32 (5 November 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Commentary
25 years of HIV-1 research progress and perspectives Mark A Wainberg, Kuan-Teh Jeang BMC Medicine 2008, 6 :31 (31 October 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study Abbas Dehghan, Mandy van Hoek, Eric JG Sijbrands, Ben A Oostra, Albert Hofman, Cornelia M van Duijn, Jacqueline CM Witteman BMC Medicine 2008, 6 :30 (16 October 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia Collins O Odhiambo, Walter Otieno, Christine Adhiambo, Michael M Odera, Jos A Stoute BMC Medicine 2008, 6 :23 (21 August 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla, J Graeme Hodgson BMC Medicine 2008, 6 :14 (24 June 2008) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]