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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Maria Kowalczuk


Welcome to BMC Biology published by BioMed Central
BMC Biology - the flagship biology journal of the BMC series - publishes research and methodology articles of special importance and broad interest in any area of biology and biomedical sciences. BMC Biology (ISSN 1741-7007) is covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.


BMC Featured articles

BMC Biology 2009, 7:22
Bacterial killing by an antimicrobial peptide has been monitored at the single-molecule level revealing four successive steps of the bactericidal process: binding, peptide association, membrane disruption and lysis of the cell.
image from wikipedia
BMC Biology 2009, 7:20
Ros and Hurst comment on the recent study showing that laterally acquired genes are highly expressed in their recipient host, and discuss the evolutionary importance of lateral gene transfer.
Image credit: Desai, additional file 5B
BMC Biology 2009, 7:19
Premature release of sperm from the Drosophila testis is prevented by F-actin and other cytoskeleton components, which together maintain developing spermatids in tight bundles within the head cyst cells in a mechanism resembling mammalian spermiation.
Credit: USDA
BMC Biology 2009, 7:18
When two cotton genomes are merged, gene expression levels are not additive as they appear, instead allelic analysis shows expression is determined by parental dominance such that the prevailing parent differs gene by gene.
PBB Protein PTH (wikipedia)
BMC Biology 2009, 7:17
A heterologous cell system recapitulates the regulation of parathyroid hormone mRNA by the calcium-sensing receptor, an aspect of calcium homestasis mediated by the parathyroid gland in vivo, but not previously replicated in a cell culture model.


BMC  Latest articles published in BMC Biology        [more info]


Research article
Single molecule resolution of the antimicrobial action of quantum dot-labeled sushi peptide on live bacteria
Sebastian Leptihn, Jia Yi Har, Jianzhu Chen, Bow Ho, Thorsten Wohland, Jeak Ling Ding
BMC Biology 2009, 7:22 (11May2009)
[Abstract] [Provisional PDF]

Research article
Specific retention of the protostome-specific PsGEF may parallel with the evolution of mushroom bodies in insect and lophotrochozoan brains
Nozomu Higuchi, Keigo Kohno, Tatsuhiko Kadowaki
BMC Biology 2009, 7:21 (7May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Commentary
Lateral gene transfer between prokaryotes and multicellular eukaryotes: ongoing and significant?
Vera ID Ros, Gregory DD Hurst
BMC Biology 2009, 7:20 (5May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
F-actin-based extensions of the head cyst cell adhere to the maturing spermatids to maintain them in a tight bundle and prevent their premature release in Drosophila testis
Bela S Desai, Seema Shirolikar, Krishanu Ray
BMC Biology 2009, 7:19 (5May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Genomic expression dominance in allopolyploids
Ryan A Rapp, Joshua A Udall, Jonathan F Wendel
BMC Biology 2009, 7:18 (1May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells
Hillel Galitzer, Vardit Lavi-Moshayoff, Morris Nechama, Tomer Meir, Justin Silver, Tally Naveh-Many
BMC Biology 2009, 7:17 (27April2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Immunomodulatory parasites and toll-like receptor-mediated tumour necrosis factor alpha responsiveness in wild mammals
Joseph A Jackson, Ida M Friberg, Luke Bolch, Ann Lowe, Catriona Ralli, Philip D Harris, Jerzy M Behnke, Janette E Bradley
BMC Biology 2009, 7:16 (22April2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Remarkable convergent evolution in specialized parasitic Thecostraca (Crustacea)
Marcos Prez-Losada, Jens T Heg, Keith A Crandall
BMC Biology 2009, 7:15 (17April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Defining behavioral and molecular differences between summer and migratory monarch butterflies
Haisun Zhu, Robert J Gegear, Amy Casselman, Sriramana Kanginakudru, Steven M Reppert
BMC Biology 2009, 7:14 (31March2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The relative ages of ectomycorrhizal mushrooms and their plant hosts estimated using Bayesian relaxed molecular clock analyses
David S Hibbett, P Brandon Matheny
BMC Biology 2009, 7:13 (10March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest selected articles from BMC Medicine


This list contains articles from BMC Medicine that may be of interest to readers of BMC Biology

Research article
Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy
Caterina Millino, Marina Fanin, Andrea Vettori, Paolo Laveder, Maria Luisa Mostacciuolo, Corrado Angelini, Gerolamo Lanfranchi
BMC Medicine 2009, 7:14 (7April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Intradermal influenza vaccination of healthy adults using a new microinjection system: a 3-year randomised controlled safety and immunogenicity trial
Jiri Beran, Arvydas Ambrozaitis, Alvydas Laiskonis, Narseta Mickuviene, Patrick Bacart, Yvan Calozet, Etienne Demanet, Stephane Heijmans, Paul Van Belle, Franoise Weber, Camille Salamand
BMC Medicine 2009, 7:13 (2April2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A compact VEGF signature associated with distant metastases and poor outcomes
Zhiyuan Hu, Cheng Fan, Chad Livasy, Xiaping He, Daniel S Oh, Matthew G Ewend, Lisa A Carey, Subbaya Subramanian, Robert West, Francis Ikpatt, Olufunmilayo I Olopade, Matt van de Rijn, Charles M Perou
BMC Medicine 2009, 7:9 (16March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Lack of utility of risk score and gynecological examination for screening for sexually transmitted infections in sexually active adolescents
Eleuse MB Guimares, Mark DC Guimares, Maria Aparecida S Vieira, Ndia M Bontempo, Mirian SS Seixas, Mnica SD Garcia, Lyana ES Daud, Rejane LM Crtes, Maria de Ftima C Alves
BMC Medicine 2009, 7:8 (11March2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical A42 reduces their differentiation potential
Markus Uhrig, Peter Brechlin, Olaf Jahn, Yuri Knyazev, Annette Weninger, Laura Busia, Kamran Honarnejad, Markus Otto, Tobias Hartmann
BMC Medicine 2008, 6:38 (16December2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study
Jeanne C Latourelle, Mei Sun, Mark F Lew, Oksana Suchowersky, Christine Klein, Lawrence I Golbe, Margery H Mark, John H Growdon, G Frederick Wooten, Ray L Watts, Mark Guttman, Brad A Racette, Joel S Perlmutter, Anwar Ahmed, Holly A Shill, Carlos Singer, Stefano Goldwurm, Gianni Pezzoli, Michela Zini, Marie H Saint-Hilaire, Audrey E Hendricks, Sally Williamson, Michael W Nagle, Jemma B Wilk, Tiffany Massood, Karen W Huskey, Jason M Laramie, Anita L DeStefano, Kenneth B Baker, Ilia Itin, et al.
BMC Medicine 2008, 6:32 (5November2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Commentary
25 years of HIV-1 research progress and perspectives
Mark A Wainberg, Kuan-Teh Jeang
BMC Medicine 2008, 6:31 (31October2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study
Abbas Dehghan, Mandy van Hoek, Eric JG Sijbrands, Ben A Oostra, Albert Hofman, Cornelia M van Duijn, Jacqueline CM Witteman
BMC Medicine 2008, 6:30 (16October2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia
Collins O Odhiambo, Walter Otieno, Christine Adhiambo, Michael M Odera, Jos A Stoute
BMC Medicine 2008, 6:23 (21August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla, J Graeme Hodgson
BMC Medicine 2008, 6:14 (24June2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

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