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Diagnosis of gastric syphilis by direct immunofluorescence staining and real-time PCR testing.

Journal of Clinical Microbiology 2006; 44(9):3452-3456.

Chen C-Y, Chi K-H, George RW, Cox DL, Srivastava A, Silva MR, Carneiro F, Lauwers GY, Ballard RC.

Abstract
We report on a case of gastric syphilis in a patient with chronic dyspepsia. The diagnosis was established by serology and the demonstration of spirochetes in diffusely inflammed gastric mucosa by staining with a fluorescent monoclonal antibody specific for pathogenic treponemes and by the detection of specific treponemal DNA sequences by a real-time PCR.