STYRA R, CONLY J, LOW DE, GREEN K, BURT J, DEVINS J, MCGREER A; Interscience Conference on Antimicrobial Agents and Chemotherapy; THE QUALITY OF LIFE STUDY GROUP.
Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 1999 Sep 26-29; 39: 633 (abstract no. 1692).
Univ. Health Network, Toronto, Ontario, CANADA
BACKGROUND: Isolation precautions are often used for patients colonized or infected with antibiotic resistant organisms. This is the first study to identify the impact of isolation for colonization and infection with VRE and MRSA on quality of life (QOL).METHODS: Consenting patients from 12 Toronto institutions having a first episode of infection or colonization with MRSA or VRE, were assessed 4 weeks after identification of MRSA/VRE (Time 1) and again at 6 months (Time 2). Data was collected using standardized questionnaires measuring functional status, social support, optimism, illness intrusiveness, self worth, mental health state, and demographics.RESULTS: 54 (94.7%) of the 57 patients enrolled to date were MRSA positive, and 3 (5.3%) were VRE positive. The mean age of participants is 65.19 (range 21.0-94.0) and 28 (49.1%) are male. Interviews at Time 2 are complete for 21/57 (36.8%), and enrollment is ongoing. The Illness Intrusiveness Scale (IIS) measurements showed a mean of 42.24 (SD=22.14) at Time 1, which is similar to that of patients with Multiple Sclerosis. The mean of IIS at Time 2 was 30.28 (SD=17.25), (p<0.05) which is similar to that of renal dialysis outpatients. Center for Epidemiologic Studies-Depression Scale (CES-D) scores at Time 1 did not differ significantly from the Time 2 scores (p< 0.10) and did not reach values consistent with depression. Self esteem score at Time 1 (mean=32.57, SD=4.62) was not significantly different from the Time 2 score (mean=30.71, SD=4.48). For all 57 patients with Time 1 interviews complete, 40 (70.2%) were in strict isolation. Patients in strict isolation had higher mean IIS and CES-D scores than patients in less restrictive isolation, (p<0.05) and (p<0.001) respectively.CONCLUSION: Patients, while in isolation did not develop symptomatic depression and their self-esteem remained intact. QOL improved when patients were no longer in isolation, or were in less restrictive isolation.
Publication Types:
Keywords:
- Anti-Bacterial Agents
- Communicable Diseases
- Enterococcus
- Epidemiologic Studies
- Humans
- Infection Control
- Male
- Staphylococcal Infections
- Staphylococcus aureus
Other ID:
UI: 102246222
From Meeting Abstracts