2006 Annual Report 4d.Progress report. This report serves to document research conducted under a Reimbursable Agreement through USDA CSREES grant to Univ. Massachusetts, Amherst for the Veterinary Immunological Reagents Network with the USDA ARS BARC APDL scientist serving as the Chair for swine reagents. Additional details of research can be found in the report from the parent project 1265-32000-079-00D: Strategies to Control Swine Parasites Affecting Food Safety. A major obstacle to advances in veterinary immunology and disease control is the lack of sufficient immunological reagents. This USDA CSREES for a Veterinary Immunological Reagents Network, was funded in 2006 through a USDA CSREES grant to Univ. Massachusetts, Amherst, to establish the Veterinary Immunological Reagents Network to begin to address this immunological reagent gap for the US veterinary immunology research community. This is a 4 year multi-species effort which will support immunological reagents specific for ruminants, swine, poultry, equine and aquaculture species, with the USDA ARS BARC APDL scientist serving as the Chair for swine reagents. The emphases for swine will be on developing and characterizing bioactive immune proteins, cloned cytokine and chemokine proteins, as well as monoclonal antibodies (mAbs) to these proteins and their receptors. Additional mAb will be produced to swine cell subset proteins, the CD antigens, and toll-like receptor (TLR) proteins. Reagents developed with this grant will be used for disease and vaccine research by veterinary immunologists, pathologists and microbiologists. Review Publications Baldwin, C., Hansen, J.D., Horohov, D., Labresh, J., Lillehoj, H.S., Lunney, J.K., Miller, N.W., Wilson, M., Bengten, E., Chinchar, G., Wagner, B. 2006. The U.S. veterinary immune reagents network. In: Proceedings of International Veterinary Vaccines and Diagnostics Conference, June 25-29, 2006, Oslo, Norway. p. 34.