Technical Abstract: Methyl bromide has commonly been used to control Replant Disorder when planting a new vineyard into the same field from which an old vineyard was removed. With the ban on import and manufacture in effect since Jan. 1, 2005, growers need alternatives to methyl bromide for perennial crops that demonstrate efficacy beyond the first growing season. After six growing seasons, the drip-applied 1,3-dichloropropene (1,3-D) and shank-injected iodomethane continue to demonstrate control comparable to methyl bromide of both the rootknot (Meloidogyne spp.) and citrus (Tylenchulus semipentrans) nematode populations for most treatment/nematode/ rootstock combinations. Citrus nematode populations on Thompson Seedless and Teleki 5C rootstock in plots subjected to chemical treatments were higher than in past years, but remained lower than populations in non-chemical treatments. The rootknot nematode populations on Harmony rootstock remained very low for all treatments, but the citrus nematode populations were highest on Harmony. Yield in the Thompson Seedless plots treated with iodomethane or 1,3-D delivered in 4 inches of water was significantly greater than in plots treated with 1-year fallow alone or followed by a 1,3-D treatment. After five growing seasons in a Long Term Fallow trial, there were no significant differences in rootknot or citrus nematode populations in one, two, or three-year fallow as compared to the untreated control. There was no significant difference in yield between treatments in own-rooted Thompson Seedless and Thompson Seedless on Harmony. In a 3rd trial, rootknot nematode control comparable to methyl bromide was achieved on Thompson Seedless with InLine and propargyl bromide and for citrus nematode with iodomethane + chloropicrin, propargyl bromide, and InLine. On the more resistant Freedom rootstock, iodomethane + chloropicrin, propargyl bromide and InLine treatments controlled rootknot and citrus nematodes comparable to methyl bromide. Nematode control on the 1103P rootstock was comparable to methyl bromide for iodomethane + chloropicrin and propargyl bromide. In a 4th trial, at the end of the first growing season the largest vines were grown in plots treated with methyl bromide for all variety/rootstock combinations and the smallest vines were grown in either the untreated plots or plots treated with sodium azide. Nematode populations on all variety/rootstock combinations after 2 growing seasons in plots treated with iodomethane + chloropicrin or 1,3-D + chloropicrin were comparable to methyl bromide. Rootknot nematode populations in azide treated plots were comparable to populations in the untreated control.