Appendix Table 3. Cohort Studies of Lung Cancer Screening with Chest X-ray (CXR)
Study, Year |
Study Population |
Intervention |
Number Malignancies (%) |
Percent Resectable |
Survival |
Philadelphia Neoplasm Research Project, 195148,49 |
6,136 men, age 45+ |
Photofluorograms and questionnaires every 6 mos for 10 yrs |
Prevalence:
84 (1.37)
Incidence:
121 |
35 |
8% (5 yrs) |
Tokyo Metropolitan Government Study, 195351 |
1,871,374 men and women, all ages |
Intermittent CXR over 26 yrs (sputum cytology in some) |
193 (0.01) |
56 |
44% (5 yrs for resectable tumors) (usual 5-yr survival at that time, 20%) |
Veterans Administration Trial, 195850 |
141,607 men, median age 62.8 |
CXR and sputum cytology |
73 (0.052) |
36 |
17% (32 mos) |
South London Cancer Study, 195952 |
67,400 men, age 45+ |
CXR every 6 mos |
234 (0.35) |
56 |
18% (4 yrs) (usual survival at that time, 9%) |
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