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2004 Case DefinitionClinical Description Staphylococcus aureus can produce a variety of syndromes with clinical manifestations including skin and soft tissue lesions, empyema, pyarthrosis, bloodstream infection, pneumonia, osteomyelitis, septic arthritis, endocarditis, sepsis, and meningitis. Laboratory Criteria 1) Isolation of Staphylococcus aureus from any body site. Case Classification Confirmed: A clinically compatible case of vancomycin-intermediate or vancomycin-resistant Staphylococcus aureus that is laboratory-confirmed (MIC: 8-16 µg/ml for VISA and MIC: ≥32 µg/ml for VRSA). Comment
References NCCLS. (2003) Performance standards for antimicrobial susceptibility
testing; Thirteenth informational supplement M100-S13 (M7). NCCLS, Wayne,
Pa.
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