Clinical Trials in Digestive Diseases : NIDDK

Clinical Trials in Digestive Diseases

This program supports patient-oriented clinical research focusing on digestive diseases. Small clinical studies (pilot), planning grants or phase III clinical trials may be appropriate to this program. The small clinical studies should focus on research that is innovative and/or potentially of high impact. They should lead to full scale clinical trials. Please see the current program announcement for small grants for clinical trials. Phase III clinical trials usually are multi-center and involve several hundred human subjects that are randomized to two or more treatments, one of which is usually a placebo. The aim of the trial is to provide evidence for support of, or a change in, health policy or standard of care. The interventions/treatments may include pharmacologic, nonpharmacologic, and behavioral interventions given for disease prevention, prophylaxis, diagnosis, or therapy. Areas of emphasis include: Helicobacter pylori; inflammatory bowel disease; functional bowel syndrome and constipation; non-ulcer dyspepsia; celiac disease; intestinal failure, short gut syndrome and small bowel transplantation.

Clinical trials may be funded by one of several mechanisms: a research project grant, a cooperative agreement, a planning grant, or a contract. Please see the current program announcement for small grants for clinical trials.

For more information, contact Dr. Patricia Robuck, Program Director for Clinical Trials in Digestive Diseases and Nutrition.

National Commission on Digestive Diseases

The Director of the NIH, Dr. Elias A. Zerhouni, has established a National Commission on Digestive Diseases based on the mutual interest in advancing digestive diseases research shared by the NIH and the Congress.

Resources for Researchers

Clinical Research


Related Study Sections

See Also

Funding Opportunities


Related Reports

Funding for Special Communities


Related Organizations

Committees and Advisory Groups

Page last updated: January 20, 2009

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