Abstract: Lessons Learned for the National Children's Study from the National Institute of Environmental Health Sciences/U.S. Environmental Protection Agency Centers for Children's Environmental Health and Disease Prevention Research
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Citation: Kimmel CA, Collman GW, Fields N, Eskenazi B. Lessons learned for the National Children's Study from the National Institute of Environmental Health Sciences/U.S. Environmental Protection Agency Centers for Children's Environmental Health and Disease Prevention Research. Environmental Health Perspectives 2005 Oct;113(10):1414-8.
Abstract
This mini-monograph was developed to highlight the experiences of the National
Institute of Environmental Health Sciences (NIEHS) /U.S. Environmental Protection
Agency (EPA) Centers for Children's Environmental Health and Disease Prevention
Research, focusing particularly on several areas of interest for the National
Children's Study. These include general methodologic issues for conducting
longitudinal birth cohort studies and community-based participatory research
and for measuring air pollution exposures, pesticide exposures, asthma, and
neurobehavioral toxicity. Rather than a detailed description of the studies
in each of the centers, this series of articles is intended to provide information
on the practicalities of conducting such intensive studies and the lessons
learned. This explication of lessons learned provides an outstanding opportunity
for the planners of the National Children's Study to draw on past experiences
that provide information on what has and has not worked when studying diverse
multiracial and multiethnic groups of children with unique urban and rural
exposures. The Children's Centers have addressed and overcome many hurdles
in their efforts to understand the link between environmental exposures and
health outcomes as well as interactions between exposures and a variety of
social and cultural factors. Some of the major lessons learned include the
critical importance of long-term studies for assessing the full range of developmental
consequences of environmental exposures, recognition of the unique challenges
presented at different life stages for both outcome and exposure measurement,
and the importance of ethical issues that must be dealt with in a changing
medical and legal environment. It is hoped that these articles will be of value
to others who are embarking on studies of children's environmental health. Key
words: asthma, autism, children, environmental
health, National
Children's Study, NIEHS/EPA
Children's Centers, obesity, pregnancy.