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Award Abstract #0733868
SGER: Biophotonics for Diagnosis of Pancreatic Cancer
| NSF Org: |
CBET
Division of Chemical, Bioengineering, Environmental, and Transport Systems
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| Initial Amendment Date: |
May 1, 2007 |
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| Latest Amendment Date: |
June 6, 2008 |
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| Award Number: |
0733868 |
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| Award Instrument: |
Standard Grant |
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| Program Manager: |
Leon Esterowitz
CBET Division of Chemical, Bioengineering, Environmental, and Transport Systems
ENG Directorate for Engineering
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| Start Date: |
July 1, 2007 |
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| Expires: |
December 31, 2008 (Estimated) |
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| Awarded Amount to Date: |
$160349 |
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| Investigator(s): |
Vadim Backman v-backman@northwestern.edu (Principal Investigator)
Randall Brand (Co-Principal Investigator)
Hemant Roy (Co-Principal Investigator)
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| Sponsor: |
Northwestern University
633 CLARK ST
EVANSTON, IL 60208 847/491-3003
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| NSF Program(s): |
BIOPHOTONICS, IMAGING &SENSING
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| Field Application(s): |
0000099 Other Applications NEC
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| Program Reference Code(s): |
OTHR, 9237, 7237, 005E, 0000
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| Program Element Code(s): |
7236
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ABSTRACT
CBET-0733868 Backman Pancreatic cancer (PC) has the worst prognosis of any major cancer, with a five-year survival rate below 5%. The reasons for the lethality of PC relates to its tendency to be
diagnosed at a late stage given that potentially curable stages of disease are often
clinically silent. Survival rate dramatically depends on the stage at which PC is
diagnosed. However, pancreatic cancer is insidious in that the development of symptoms
generally portend unresectable and hence uncurable disease. One of the major hurdles
preventing screening for PC is that essentially any interrogation of the pancreas may lead
to serious complications (~20% complication rate). Thus, finding a pre-screening method in
which patients are risk-stratified would be critical for designing screening strategies.
This project focuses on development of a biophotonics approach (a partial wave spectroscopic microscopic technique), to address this problem.
PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH
(Showing: 1 - 1 of 1).
Y. Liu, R. E. Brand, V. Turzhitsky, Y. L. Kim, H. K. Roy, N. Hasabou, C. Sturgis, D. Shah, C. Hall, V. Backman.
"Optical Markers in Duodenal Mucosa Predict the Presence of Pancreatic Cancer,"
Clinical Cancer Research,
v.13,
2007,
p. 4392.
(Showing: 1 - 1 of 1).
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