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Acceptable Substitutes in Cold Storage Warehouses

Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.

Unacceptable substitutes

Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.

Acceptable Substitutes for CFCs (class I ODS) in Cold Storage Warehouses

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/New
HCFC-22   12, 502 R, N
Ikon A   12 R, N
Ikon B   12 R, N
THR-02   12 R, N
HFC-134a   12 R, N
HFC-227ea   12 N
R-401A, R-401B MP-39, MP-66 12 R, N
R-402A, R-402B HP-80, HP-81 502 R, N
R-404A HP-62 502, 12, 500 R, N
R-406A GHG 12, 500 R
R-407A, R-407B Klea 407A, 407B 502 R, N
R-408A (HCFC Blend Epsilon)   502 R
R-411A, R-411B   12, 500, 502 R, N
R-507 AZ-50 502 R, N
Free Zone (HCFC Blend Delta) Free Zone / RB-276 12 R, N
Freeze 12 Freeze 12 12 R, N
FRIGC FR-12 (HCFC Blend Beta) FRIGC FR-12 12, 500 R, N
GHG-X4 GHG-X4, Autofrost, Chill-it 12, 500 R, N
GHG-X5 GHG-X5 12, 500 R, N
GHG-HP (HCFC Blend Lambda) GHG-HP 12 R, N
G2018C G2018C 12, 500, 502 R, N
Hot Shot Hot Shot, Kar Kool 12, 500 R, N
HCFC-22/HCFC-142b   12 R, N
THR-04 THR-04 502 R, N
FOR12A FOR12A 12 R, N
FOR12B FOR12B 12 R, N
SP34E SP34E 12 R, N
Ammonia Vapor Compression   all N
HFC-134a/HBr (92/8) as the primary heat transfer fluid in secondary-loop equipment   12, 502 N
Evaporative/Desiccant Cooling   all N
Pressure Stepdown   all N
Self-chilling cans using CO 2   12, 500, 502 N
R-407C Suva 407C, Klea 407C 502 R, N
R-420A Choice R-420A 12, 500 R, N
RS-24 (2002 formulation)   12 R, N
R-421B Choice R421B 12, 502 R, N
R-426A RS-24 12 R, N
R-422C ICOR XLT1 502 R, N
R-428A RS-52 502 R, N
KDD6 KDD6 12 R, N
Key: R = Retrofit Uses, N = New Uses

Acceptable Substitutes for HCFCs (class II ODS) in Cold Storage Warehouses

Substitute (Name Used in the Federal Register) Trade Name Refrigerant Being Replaced Retrofit/New
R-410A, R-410B AZ-20, Suva 9100, Puron   N
THR-03     N
ISCEON 59, NU-22, R-417A Isceon 59, NU-22   R, N
R-407C Suva 9000, Klea 66   R, N
R-507, R507A AZ-50   R, N
Ammonia Vapor Compression     N
Ammonia Absorption     N
R-404A HP62   R, N
Self-Chilling cans using CO 2     R, N
RS-44 (2003 formulation)   22 R, N
ISCEON 79 ISCEON 79   R, N
R-421B Choice R421B 22 R, N
R-422D ISCEON MO29 22 R, N
R-424A RS-44 22 R, N
R-426A RS-24 22 R, N
KDD5 KDD5 22 R, N
R-434A RS-45 22 R, N
R-428A RS-52 22, 22 blends including R-402A, -403B, -408A, AND -411B R, N
R-125/290/134a/600a (55.0/1.0/42.5/1.5) ICOR AT-22 22 R, N
R-422B XAC1, NU-22B 22 R, N
R-422C XLT1 22, 402A, 402B, 408A R, N
R-407A KLEA 60, KLEA 407A 22, 22 blends including R-401A, -401B, -402A, and -402B R, N
Key: R = Retrofit Uses, N = New Uses

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