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Acceptable Substitutes for CFC-114 and CFC-11 in Chillers and Other Refrigerants
Substitutes are reviewed on the basis of ozone depletion potential, global warming potential, toxicity, flammability, and exposure potential. Lists of acceptable and unacceptable substitutes are updated several times each year. A chronological list of SNAP updates is also available.
Note: SNAP-related information published in the Federal Register takes precedence over all information on this page.
| Substitute (Name Used in the Federal Register) | Trade Name | Retrofit/New |
|---|---|---|
| HCFC-22 | N | |
| HCFC-123 | N | |
| HCFC-124 | R,N | |
| HFC-134a | N | |
| HFC-227ea | N | |
| HFC-236fa | R,N | |
| Ammonia Vapor Compression | N | |
| Evaporative Cooling | N | |
| Desiccant Cooling | N | |
| Ammonia / Water Absorption | N | |
| Water / Lithium Bromide Absorption | N | |
| HFC-245fa | Genetron® 245fa | R, N |
Key: R = Retrofit Uses, N = New
Uses
| Substitutes (Name Used in the Federal Register) | Trade Name | Retrofit/New |
|---|---|---|
| HCFC-123 | R, N | |
| HCFC-22 | N | |
| HFC-134a | N | |
| HFC-227ea | N | |
| HFC-245fa | N | |
| Ammonia Vapor Compression | N | |
| Evaporative Cooling | N | |
| Desiccant Cooling | N | |
| Ammonia / Water Absorption | N | |
| Water / Lithium Bromide Absorption | N |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for CFCs (class I ODS) in Reciprocating and Screw Chillers
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| HCFC-22 | 12, 500 | N | |
| Ikon B | 12 | N | |
| THR-02 | 12 | N | |
| HFC-134a | 12, 500 | R, N | |
| HFC-227ea | 12, 500 | N | |
| R-401A, R-401B | MP-39, MP-66 | 12, 500 | R, N |
| R-411A, R-411B | 12, 500 | R, N | |
| Free Zone (HCFC Blend Delta) | Free Zone / RB-276 | 12, 500 | R, N |
| Freeze 12 | Freeze 12 | 12, 500 | R, N |
| FRIGC FR-12 (HCFC Blend Beta) | FRIGC FR-12 | 12, 500 | R, N |
| GHG-X4 | GHG-X4, Autofrost, Chill-it | 12, 500 | R, N |
| GHG-X5 | GHG-X5 | 12, 500 | R, N |
| G2018C | G2018C | 12, 500 | R, N |
| Hot Shot | Hot Shot, Kar Kool | 12, 500 | R, N |
| HCFC-22/HCFC-142b | 12 | R, N | |
| FOR12A | FOR12A | 12 | R, N |
| FOR12B | FOR12B | 12 | R, N |
| SP34E | SP34E | 12 | R, N |
| Evaporative/Desiccant Cooling | 12, 500 | N | |
| R-407C | Suva 407C, Klea 407C | 502 | R, N |
| R-420A | Choice R-420A | 12, 500 | R, N |
| R-422C | ICOR XLT1 | 502 | R, N |
| KDD6 | KDD6 | 12 | R, N |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for HCFCs (class II ODS) in Reciprocating and Screw Chillers
| Substitute (Name Used in the Federal Register) | Trade Name | Retrofit/ New |
|---|---|---|
| THR-03 | N | |
| ISCEON 59, NU-22, R-417A | Isceon 59, NU-22 | R, N |
| R-410A, R-410B | AZ-20, Suva 9100, Puron | N |
| R-407C | Suva 9000, Klea 66 | R, N |
| R-507, R-507A | AZ-50 | N |
| NU-22 | NU-22 | R, N |
| Ammonia Vapor Compression With Secondary Loop | N | |
| Ammonia Absorption or Water/Lithium Bromide Absorption | N | |
| Evaporative/Desiccant Cooling | N | |
| R-404A | HP62 | R, N |
| R-125/134a/600a (28.1/70.0/1.9) | R, N | |
| RS-44 | RS-44 | R, N |
| R-421A | Choice R421A | R, N |
| R-422D | ISCEON MO29 | R, N |
| R-424A | RS-44 | R, N |
| KDD5 | KDD5 | R, N |
| R-434A | RS-45 | R, N |
| R-125/290/134a/600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | R, N |
| R-422B | XAC1, NU22B | R, N |
| R-422C | XLT1 | R, N |
| R-427A | Forane 427A | R |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for CFC-12 & R-500 (class I ODS) in Centrifugal Chiller
| Substitute (Name Used in the Federal Register) | Trade Name | Refrigerant Being Replaced | Retrofit/ New |
|---|---|---|---|
| HCFC-22 | 12, 500 | N | |
| HCFC-123 | 12, 500 | N | |
| HFC-134a | 12, 500 | R, N | |
| Ikon A | 12 | R, N | |
| Ikon B | 12 | R, N | |
| HFC-227ea | 12, 500 | N | |
| R-406A | GHG | 12, 500 | R, N (R-500 only) |
| Free Zone (HCFC Blend Delta) | Free Zone / RB-276 | 12, 500 | R, N |
| Freeze 12 | Freeze 12 | 12, 500 | R, N |
| FRIGC FR-12 (HCFC Blend Beta) | FRIGC FR-12 | 12, 500 | R, N |
| GHG-X4 | GHG-X4, Autofrost, Chill-it | 12, 500 | R, N |
| GHG-X5 | GHG-X5 | 12, 500 | R, N |
| G2018C | G2018C | 12, 500 | R, N |
| Hot Shot | Hot Shot, Kar Kool | 12, 500 | R, N |
| HCFC-22/HCFC-142b | 12 | R, N | |
| R-420A | Choice R-420A | 12, 500 | R, N |
| FOR12A | FOR12A | 12 | R, N |
| FOR12B | FOR12B | 12 | R, N |
| Ammonia Vapor Compression With Secondary Loop | 12, 500 | N | |
| Evaporative/Desiccant Cooling | 12, 500 | N | |
| Ammonia / Water Absorption | 12, 500 | N | |
| Water / Lithium Bromide Absorption | 12, 500 | N | |
| THR-02 | THR-02 | 12 | N |
| Isceon 39TC | Isceon 39TC | 12 | R, N |
Key: R = Retrofit Uses, N = New
Uses
Acceptable Substitutes for HCFCs (class II ODS) in Centrifugal Chillers
| Substitute (Name Used in the Federal Register) | Trade Name | Retrofit/ New |
|---|---|---|
| THR-03 | N | |
| ISCEON 59, NU-22, R-417 | Isceon 59, NU-22 | R, N |
| R-410A, R-410B | AZ-20, Suva 9100, Puron | N |
| R-407C | Suva 9000, Klea 66 | R, N |
| R-507, R-507A | AZ-50 | R, N |
| Ammonia Vapor Compression With Secondary Loop | N | |
| Ammonia Absorption or Water/Lithium Bromide Absorption | N | |
| Evaporative/Desiccant Cooling | N | |
| R-404A | HP62 | R, N |
| R-125/134a/600a (28.1/70.0/1.9) | R, N | |
| RS-44 | RS-44 | R, N |
| R-421A | Choice R421A | R, N |
| R-422D | ISCEON MO29 | R, N |
| R-424A | RS-44 | R, N |
| KDD5 | KDD5 | R, N |
| RS-45 (ASHRAE proposed designation: R-434A) | RS-45 | R, N |
| R-125/290/134a/600a (55.0/1.0/42.5/1.5) | ICOR AT-22 | R, N |
| HFC-245fa | Genetron® 245fa | R, N |
| R-422B | XAC1, NU-22B | R, N |
| R-422C | XLT1 | R, N |
Key: R = Retrofit Uses, N = New
Uses