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Sexually Transmitted Diseases
Sexually Transmitted Diseases  >  Tracking the Hidden Epidemics 2000 (1999 data)
Tracking the Hidden Epidemics 2000

A Closer Look at Human Papillomavirus (HPV)

  • An estimated 5.5 million people become infected with HPV each year in the United States, and an estimated 20 million Americans are currently infected (Cates, 1999).
  • An estimated 75 percent of the reproductive-age population has been infected with sexually transmitted HPV (Koutsky, 1997).
  • An estimated 15 percent of Americans ages 15 to 49 are currently infected (Koutsky, 1997).
  • Studies repeatedly show high levels of HPV infection in women, with the highest levels among young women.
  • A recent U.S. study among female college students found that an average of 14 percent became infected with genital HPV each year. About 43 percent of the women in the study were infected with HPV during the three-year study period (Ho, 1998).
  • Typical prevalence of HPV for women under the age of 25 is between 28 and 46 percent (Burk, 1996; Bauer, 1991).
  • Although less data are available on HPV among men, levels of current infection in men appear to be similar to those in women (DSTDP HPV Report, CDC, 1999).
  • HPV may be an even greater problem for HIV-positive men and women. HIV-positive individuals have a higher prevalence of HPV infection and precancerous lesions on the cervix and anus than HIV-negative individuals. Co-infection with HIV and HPV is most likely due to shared risk behaviors for both diseases, as well as an increased susceptibility to HPV because of a compromised immune system.
    • A San Francisco study of gay and bisexual men found that 60 percent of HIV-negative men had HPV, with almost universal HPV infection among HIV-positive individuals with severely compromised immune systems (Palefsky, unpublished data).

    • Similarly, a six-city study among high risk and HIV-infected women found that 26 per-cent of HIV-negative women were infected with HPV, but 70 percent of HIV-positive women with severely comprised immune systems were infected with HPV (Palefsky, 1998).

Genital Warts

Research indicates that approximately one per-cent of sexually active adults in the United States have genital warts. These estimates are based on select studies demonstrating levels of infection ranging from 1.5 percent among female college students treated in student health centers to 13 percent in some STD clinics (Koutsky, 1997).


Page last modified: April 6, 2001
Page last reviewed: April 6, 2001 Historical Document

Content Source: Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention