Summary: The objective of this study was to evaluate whether trace element toxicity or deficiency may have contributed to the decline of moose in northwest Minesota. The livers of 81 moose found dead in 1998 and 1999 (from three study sites) were analysed for trace elements. With the exception of Selenium and Copper, trace elements were not at toxic or deficient levels based on criteria for cattle. Selenium concentrations were deficient in 3.7 percent of livers and at a chronic toxicity level in 16 percent of livers. Copper deficiencies were observed in 39.5 percent of livers, marginally deficient in 29.5 percent, and adequate in 31 percent. Moose from agricultural areas had higher concentrations, on average, of Cadmium, Copper, Selenium and Molybdenum than moose from the bog and forested areas. Older moose had higher concentrations of Cadmium and Zinc, and lower concentrations of Copper than younger moose. Copper deficiency, which has been associated with population declines of moose in Alaska and Sweden, may be a factor in contributing to the decline of moose in Northwest Minnesota.