The park is located within the city limits of San Francisco, in the Fisherman's Wharf neighborhood, on the shoreline of San Francisco Bay.

There is no designated parking area for the park. There is metered street parking (Bring lots of quarters!), and garages and parking lots that charge various prices to park ($10 to $20 per day).

Car
From the South Bay (San Francisco International Airport/US101): Take 101 north. Follow the signs to 101 North Golden Gate Bridge. Take the Mission Street exit, at the bottom of the ramp go right on Mission Street, in two blocks go left on Van Ness Avenue, follow Van Ness Avenue (north) about 30 blocks. Turn right on North Point Street (east), then turn left on Polk Street (north). The Museum Building is straight ahead.

From the East Bay (Bay Bridge): After crossing the bridge take the Harrison Street/Embarcadero 2B exit. At the bottom of the ramp turn right (north). Turn left onto the Embarcadero. Follow the flow of traffic past Pier 39 and on to Jefferson Street. Hyde Street Pier is about 5 blocks up on the right. To reach the Museum Building, turn left on to Hyde Street and take the next right on to North Point Street. The museum is two blocks down (west) on the right.

From the North Bay (Golden Gate Bridge/Marin): Follow the Lombard Street exit. Drive east on Highway 101 through the Presidio. Bear to the right and get on Lombard. In about a mile and a half turn left (north) on to Van Ness Avenue. In four blocks turn right (east) on to North Point Street, and then left (north) on Polk Street to the Museum Building.

Plane
San Francisco International and Oakland International airports provide access.