| Study, Year (Study Began) |
Population |
Intervention |
Prevalence
(%) |
Incident Lung Cancer (No) |
Advanced Tumors Stage III, IV (%) |
Non-resectable Tumors (%) |
Mortality Rate/1,000 Person-Yearsa |
| Northwest London Mass Radiography Service, 196035,36 |
Males >40 yrs; 19% former smokers; 67% current smokers |
29,723 offered CXR every 6 mos over 3 yrs; 25,300 offered CXR at baseline and at 3 yrs |
Intervention:
31 ( 0.10 )
Control:
20 ( 0.08 ) |
Intervention:
101
Control:
76 |
Intervention:
NR
Control:
NR |
Intervention:
56
Control:
71 |
3 yr followup
Intervention:
0.7
Control:
0.8 |
| Kaiser Permanente, 196433,34 |
10,713 members aged 35-54;
17% smokers |
Intervention: 5,156 encouraged to have annual multiphasic health checkup including CXR
Control: 5,557 usual care |
NR |
NR |
NR |
NR |
16 yr followup
Intervention:
8.6
Usual care:
7.6 |
| Memorial Sloan-Kettering, 197437,63-67 |
10,040 male smokers aged ≥45 |
All participants: baseline CXR; 4,968 annual CXR and sputum cytology every 4 mos for 5-8 yrs; 5,072 annual CXR and screened over 5-8 yrs |
Dual screen:
30 (0.6)
CXR:
23 (0.46) |
Dual screen:
146
CXR:
155 |
Dual screen:
64 (1.2) (incidence)
CXR:
63 (1.2) (incidence) |
Dual screen:
49
CXR:
47 |
5-8 yr followup
Dual screen:
2.7
CXR:
2.7 |
| Johns Hopkins, 197338,68-72 |
10,387 male smokers aged ≥45 |
All participants: baseline CXR; 5,266 CXR and sputum cytology at baseline and every 4 mos; 5,161 annual CXR for 5-8 yrs |
Dual screen:
39 (0.75)
CXR:
40 (0.78) |
Dual screen:
194
CXR:
202 |
NR |
Dual screen:
53
CXR:
56 |
5-8 yr followup
Dual screen:
3.4
CXR:
3.8 |
| Mayo Lung Project, 197139,74-76,80 |
10,933 male smokers aged ≥45 |
All participants: baseline CXR, 3-day pooled sputum cytology; 4,618 to CXR and 3-day pooled sputum cytology every 4 mos for 6 yrs; 4,593 received usual care with advice for annual CXR and sputum cytology |
91 (0.83) |
Dual screen:
206
Usual care:
160 |
Dual screen:
107 (2.3)
Usual care:
109 (2.4) |
Dual screen:
32
Usual care:
19 |
20 yr followup
Intervention:
4.4
Usual care:
3.9 |
| Czech, 197540,84,85 |
6,345 male smokers aged 40-64 |
After baseline CXR: 3,171 received CXR every 6 mos over 3 yrs and 3,174 received usual care; at end of study (yrs 4-6), CXR performed annually in each group |
19 (0.30) |
Dual screen:
108
Control:
82 |
Dual screen:
53 (1.7)
Control:
46 (1.4) |
Dual screen:
77
CXR:
77 |
15 yr followup:
Dual screen:
7.8
Control:
6.8 |
| Wilde, 1972-197747 b |
All men in 14 districts aged 40-65 (n = 143,880) |
Intervention: 41,532 in 4 districts offered chest fluorography every 6 mos
Control: 102,348 in 10 districts offered chest fluorography every 12-24 mos |
Intervention:
54
Control:
68 |
Intervention:
320
Control:
599 |
NR |
Intervention:
72
Control:
81 |
10 yr followup:
Intervention:
0.8
Control:
0.6 |
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