Figure 2. Colonoscopies and life-years gained (compared with no screening) for a cohort of 1000 forty-year-olds for 18 colonoscopy screening strategies that vary by start age, stop age, and screening interval (Text Description)

This pair of graphs presents life-years gained relative to the number of colonoscopies performed. The first graph displays life-years gained using the MISCAN (Microsimulation Screening Analysis) model; the second depicts the information using the SimCRC (Simulation Model of Colorectal Cancer) model.

The horizontal axis of each graph represents colonoscopies per 1000 persons; the vertical axis of each graph represents life-years gained per 1000 persons.

Filled-in circles represent strategies starting at age 50 and 60 years; hollow circles represent strategies starting at age 40 years. The specific starting and stopping ages and the intervals between screenings are indicated or each circle by a set of numbers with an arrow pointing to the pertinent circle. For strategies starting at age 40, there is no specified stopping age or interval.

The numbers represent the following: age to begin—age to stop screening, interval. MISCAN = Microsimulation Screening Analysis; SimCRC = Simulation Model of Colorectal Cancer.

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