Laboratory of Functional and Molecular Imaging - Division of Intramural Research

K. Chuang, A.P. Koretsky
Improved Neuronal Tract Tracing Using Manganese Enhanced Magnetic Resonance Imaging with Fast T1 Mapping - Magnetic Resonance in Medicine  55 604-611 2006

S.D. Keilholz, A.C. Silva, M. Raman, H. Merkle, A.P. Koretsky
BOLD and CBV-Weighted Functional Magnetic Resonance Imaging of the Rat Somatosensory System - Magnetic Resonance in Medicine  55 316-324 2006

I. Aoki, Y. Takahashi, K. Chuang, A.C. Silva, T. Igarashi, C. Tanaka, R.W. Childs, A.P. Koretsky
Cell Labeling for Magnetic Resonance Imaging with the T1 Agent Manganese Chloride - NMR in Biomedicine  19 50-59 2006

O. Rodriguez, S. Fricke, C. Chien, L. Dettin, J. Vanmeter, E.M. Shapiro, H. Dai, M. Casimiro, L. Lleva, J. Dagata, M.D. Johnson, M.P. Lisanti, A.P. Koretsky, C. Albanese
Contrast-Enhanced in Vivo Imaging of Breast and Prostate Cancer Cells by MRI - Cell Cycle  5 113-119 2006

E.M. Shapiro, K. Sharer, Skrtic, A.P. Koretsky
In Vivo Detection of Single Cells By MRI - Magnetic Resonance in Medicine  55 242-249 2006

J.H. Duyn, P. van Gelderen, S.L. Talagala, A.P. Koretsky, J.A. de Zwart
Technological Advances in MRI Measurement of Brain Perfusion - Journal of Magnetic Resonance Imaging  22 751-753 2005

E.M. Shapiro, S. Skrtic, A.P. Koretsky
Sizing It Up: Cellular MRI Using Micron-Sized Iron Oxide Particles - Magnetic Resonance in Medicine  53 329-338 2005

C. Du, A.P. Koretsky, I. Izrailtyan, H. Benveniste
Simultaneous Detection of Blood Volume, Oxegenation, and Intracellular Calcium Changes During Cerebral Ischemia and Reperfusion in Vivo Using Photospectrometry - Journal of Cerebral Blood Flow and Metabolism  25 1078-1092 2005

U. Himmelreich, R. Weber, P. Ramos-Cabrer, S. Wegener, K. Kandal, E.M. Shapiro, A.P. Koretsky, M. Hoehn
Improved Stem Cell MR Detectability in Animal Models By Mdification of the Inhalation Gas - Molecular Imaging  4 104-109 2005

J. Lee, A.C. Silva, H. Merkle, A.P. Koretsky
Manganese-Enhanced Magnetic Resonance Imaging of Mouse Brain After Systemic Administration of MnCI2: Dose Dependent and Temporal of T1 Contrast - Magnetic Resonance in Medicine  53 640-648 2005

C. Du, A.P. Koretsky, I. Izrailtyan, H. Benveniste
Simultaneous Detection of Blood Volume, Oxegenation, and Intracellular Calcium Changes During Cerebral Ischemia and Reperfusion in Vivo Using Diffuse Reflectance and Fluorescence - Journal of Cerebral Blood Flow and Metabolism   1-15 2005

G. Pelled, S.J. Dodd, A.P. Koretsky
Catheter Confocal Fluorescence Imaging and Functional Magnetic Resonance Imaging of Local and Systems Level Recovery in the Regenerating Rodent Sciatic Nerve - NeuroImage    2005

T.C. Hu, T.F. Christian, A.H. Aletras, J.L. Taylor, A.P. Koretsky, A.E. Arai
Manganese-Enhanced Magnetic Resonance Imaging of Normal and Ischemic Canine Heart - Magnetic Resonance in Medicine  54 196-200 2005

O. Speer, N. Back, T. Buerklen, D. Brdiczka, A.P. Koretsky, T. Wallimann, O. Eriksson
Octameric Mitochondrial Creatine Kinase Induces and Stabilizes Contact Sites Between the Inner and Outer Membranes - Biochem J  385 445-450 2005

J.A. de Zwart, A.C. Silva, P. van Gelderen, P. Kellman, M. Fukunaga, R. Chu, A.P. Koretsky, J.A. Frank, J.H. Duyn
Temporal Dynamics of the BOLD fMRI Impulse Response - NeuroImage  24 667-677 2005

A.P. Koretsky, S.L. Talagala, S.D. Keilholz, A.C. Silva
MRI Detection of Regional Blood Flow Using Arterial Spin Labeling - Cambridge University Press   119-140 2005

A.P. Koretsky, A.C. Silva
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) - NMR in Biomedicine  17 527-531 2004

S.D. Keilholz, A.C. Silva, M. Raman, H. Merkle, A.P. Koretsky
Functional MRI of the Rodent Somatosensory Pathway Using Multisclice Echo Planar Imaging - Magnetic Resonance in Medicine  52 89-89 2004

G.A. MacGowan, C. Evans, T.C. Hu, D. Debrah, S. Mullet, H. Chen, C.F. Mctiernan, A.F. Stewart, A.P. Koretsky, S.G. Shroff
Troponin I Protein Kinase c Phosphorylation Sites and Ventricular Function - Cardiovascular Research  63 245-255 2004

C. Du, Y. Pan, G.A. MacGowan, A.P. Koretsky
Decreasing Motion Artifacts in Calcium-Dependent Fluorescence Transients from the Perfused Mouse Heart Using Frequency Filtering - Cell Calcium  35 144-156 2004

E.M. Shapiro, S. Skrtic, K. Sharer, J.M. Hill, C.E. Dunbar, A.P. Koretsky
MRI Detection of Single Particles for Cellular Imaging - Proc. Natl. Acad. Sci.  101 10901-10906 2004

A.P. Koretsky
New Developments in Magnetic Resonance Imaging of the Brain - NeuroRx: The Journal of the American Society for Experimental NeuroTherapeutics  1 155-164 2004

I. Aoki, Y.L. Wu, A.C. Silva, R.M. Lynch, A.P. Koretsky
In Vivo detection of Neuroarchitecture in the Rodent Brain Using Manganese-Enhanced MRI - NeuroImage  22 1046-1059 2004

A.C. Silva, J. Lee, I. Aoki, A.P. Koretsky
Manganese-Enhanced magnetic Resonance Imaging (MEMRI): Methodological and Pratical Considerations - NMR in Biomedicine  17 532-543 2004

J. Lee, A.P. Koretsky
Manganese Enhanced Magnetic Resonance Imaging - Current Pharmaceutical Biotechnology  5 529-537 2004

K.A. Hinds, J.M. Hill, E.M. Shapiro, M.O. Laukkanen, A.C. Silva, C.A. Combs, T.R. Varney, R.S. Balaban, A.P. Koretsky, D.E. Cynthia
Highly Efficient Endosomal Labeling of Progenitor and Stem Cells with Large Magnetic Particles Allows Magnetic Resonance Imaging of Single Cells - Blood  102 144-156 2003

C. Grabill, A.C. Silva, S.S. Smith, A.P. Koretsky, T.A. Rouault
MRI Detection of Ferritin Iron Overload and Associated Neuronal Pathology in Iron Regulatory Protein-2 Knockout Mice - Brain Research  971 144-156 2003

D.E. Montgomery, B.M. Wolska, W.G. Pyle, B.B. Roman, J.C. Dowell, P.M. Buttrick, A.P. Koretsky, P. Del Nido, and R.J. Solaro
Alpha-Adrenergic Response and Myofilament Activity in Mouse Hearts Lacking PKC Phosphorylation Sites on Cardiac TnI - Am. J. Physiol. Heart Circ. Physiol.  282 H2397-H2405 2002

A.C. Silva and A.P. Koretsky
Laminar Specificity of fMRI Onset Times During Somatosensory Stimulation in the Rat - Proc. Natl. Acad. Sci.  99 15182-15187 2002

C. Du, Y. Pan, G.A. MacGowan, A.P. Koretsky
Separation of Calcium Transients and Motion Artifact Using Frequency Filtering of Fluorescent Signals Arising from the Perfused Mouse Heart - Proc. SPIE    2002

I. Aoki, C. Tanaka, T. Takegami, T. Ebisu, M. Umeda, M. Fukunaga, A.C. Silva, A.P. Koretsky, and S. Naruse
Dynamic Activity-Induced Manganese Dependent Contrast Magnetic Resonance Imaging (DAIM MRI) - Magn. Resonance Med.  48 927-933 2002

E.L. Barbier, S. Marrett, A. Danek, A. Vortmeyer, P. van Gelderen, J. Duyn, P. Bandettini, J. Grafman, A.P. Koretsky
Imaging Cortical Anatomy by High Resolution MR at 3.0T: Detection of the Stripe of Gennari in Visual Area 17 - Magn. Resonance Med.    2002

R.G. Pautler, A.P. Koretsky
Tracing Odor Induced Activation in the Olfactory Bulbs of Mice Using Manganese Enhanced Magnetic Resonance Imaging - NeuroImage  16 441-448 2002

E.L. Barbier, K.S. St. Lawrence, E. Grillon, A.P. Koretsky, M. DeCorps
A Model of Blood-Brain Barrier Permeability to Water: Accounting for Blood Inflow and Longitudinal Relaxation Effects - Magn. Resonance Med.  47 1100-1109 2002

S.J. Dodd, D.S. Williams, C. Olsen, A.C. Silva, A.P. Koretsky, and C. Ho
Open Gradient Coil Designs for Magnetic Resonance Imaging - Rev. Sci. Instru.  73 2208-2210 2002

A.P. Koretsky
Functional Assessment of Tissues with Magnetic Resonance Imaging - Annals of the New York Academy of Sciences  961 144-156 2002

E.L. Barbier, A.C. Silva, S. Kim, A.P. Koretsky
Perfusion Imaging Using Dynamic Arterial Spin Labeling (DASL) - Magnetic Resonance in Medicine  45 144-156 2001

N. Askenasy, A.P. Koretsky
Transgenic Livers Expressing Mitochondrial and Cytosolic Creatine Kinase: Mitochondrial Creatine Kinase Modulates Free ADP Levels - Am. J. Physiol.  282 C338-C346 2001

G.A. MacGowan, C. Du, D.F. Wieczorek, A.P. Koretsky
Compensatory Changes in Ca2+ and Myocardial O2 Consumption in Beta-tropomyosin Transgenic Hearts - Am. J. Physiol.  281 H2539-H2548 2001

G.A. MacGowan, C. Du, A.P. Koretsky
High Calcium and Dobutamine Positive Inotropy in the Perfused Heart: Myofilament Calcium Responsiveness, Energetic Economy, and Effects of Protein Kinase C Inhibition - BMC Physiology  1 144-156 2001

A.J. Wiethoff, J.R. Harkema, A.P. Koretsky, W.E Brown
Identification of Mucosal Injury in the Murine Nasal Airways by Magnetic Resonance Imaging: Site Specific Lesions Induced by 3-Methylindole - Toxicology and Applied Pharmacology  175 144-156 2001

T.C. Hu, R.G. Pautler, G.A. MacGowan, A.P. Koretsky
Manganese-Enhanced MRI of Mouse Heart During Changes in Inotropy - Magnetic Resonance in Medicine  46 144-156 2001

G. A. MacGowan, A.P. Koretsky
Inotropic and Energetic Effects of Altering the Force-Calcium Relationship: Mechanisms, Experimental Results, and Potential Molecular Targets - Journal of Cardiac Failure  6 144-156 2000

J.F. Watchko, M.F. Daood, B. Weiringa, and A.P. Koretsky
Myofibrillar or Mitochondrial Creatine Kinase Deficiency Alone does not Impair Mouse Diaphragm Isotonic Function - J. Appl. Physiol.  88 973-980 2000

E. Barbier, A. Silva, H. Kim, D. Will and A. P. Koretsky
Perfusion Analysis Using Dynamic Arterial Spin Labeling - Magn. Resonan. Med.   41 299-308 1999

T.F. Budinger, D.A. Benaron, and A.P. Koretsky
Imaging Transgenic Animals - Annu. Rev. Biomed. Eng.   1 611-648 1999

S.D. Forman, A.C. Silva, N. Dedousis, E.L. Barbier, J.D. Fernstrom, and A.P. Koretsky
Simultaneous Glutamate and Perfusion fMRI Responses to Regional Brain Stimulation - J. Cerebral Blood Flow and Met.   18 1064-1074 1998

R.G. Pautler, A.C. Silva, and A.P. Koretsky
Tract Tracing In Vivo Neuronal Using Manganese Enhanced Magnetic Resonance Imaging - Magn. Resonan. Med.   40 740-748 1998

D.J. Grandis, G.A. MacGowan, A.P. Koretsky
Comparison of the Effects of ORG 30029, Dobutamine and High Perfusate Calcium on Function and Metabolism in Rat Heart - Journal of Molecular and Cellular Cardiology  30 2605-2612 1998

A.P. Koretsky
Insights Into Cellular Energy Metabolism from Transgenic Mice - Physiological Reviews  75 144-156 1995

C.J. Eskey, A.P. Koretsky, M.M. Domach, R.K. Jain
Role of Oxygen vs. Glucose in Energy Metabolism in a Mammary Carcinoma Perfused Ex Vivo - Proc. Natl. Acad. Sci.  90 144-156 1993

J.A. Detre, J.S. Leigh, D.S. Williams, A.P. Koretsky
Perfusion Imaging - Magnetic Resonance in Medicine  23 144-156 1992

D.S. Williams, J.A. Detre, J.S. Leigh, A.P. Koretsky
Magnetic Resonance Imaging of Perfusion Using Spin Inversion of Arterial Water - Proc. Natl. Acad. Sci.  89 144-156 1992

A.P. Koretsky, D.S. Williams
Application of Localized in Vivo NMR to Whole Organ Physiology in the Animal - Annual Review of Physiology  54 144-156 1992

A.P. Koretsky
Investigation of Cell Physiology in the Animal Using Transgenic Technology - American Journal Physiology  262 144-156 1992

M.J. Brosnan, L. Chen, T. Van dyke, A.P. Koretsky
Free ADP Levels in Transgenic Mouse Liver Expressing Creatine Kinase - Journal of Biological Chemistry  265 144-156 1990

J.A. Detre, C.J. Eskey, A.P. Koretsky
Measurement of Cerebral Blood Flow in Rat Brain by 19F-NMR Detection of Trifluoromethane Washout - Magnetic Resonance in Medicine  15 144-156 1990

A.P. Koretsky, M.J. Brosnan, L. Chen, T. Van dyke
NMR Detection of Creatine Kinase Expressed in Liver of Transgenic Mice - Proc. Natl. Acad. Sci.  87 144-156 1990

A.P. Koretsky, R.S. Balaban
Determination of Pyridine Nucleotide Fluorescence from the Perfused Heart Using an Internal Standard - American Journal Physiology  253 144-156 1987

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