CounterACT Publications 2009

CounterACT Publications

Neurotoxic Organophosphorus Poisons (e.g. anti-convulsants, anti-seizures, neuroprotectants, cholinesterase reactivators, nerve agent bioscavengers)

Albuquerque EX, Pereira, EF, Alkondon M, Rogers SW. (2009) Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol. Rev. 89(1): 73-120.  Abstract

Alkondon M, Aracava Y, Pereira ER, Albuquerque EX. (2009) A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus. J Pharmacol Exp Ther. 328(1): 69-82.  Abstract 

Boado RJ, Zhang Y, Zhang Y, Wang Y, Pardridge WM. (2008) IgG-Paraoxonase-1 fusion protein for targeted drug delivery across the human blood-brain barrier. Mol Pharm. [Epub ahead of print]  Abstract

Budai M, Chapela P, Grof P, Zimmer A, Wales ME, Wild JR, Klebovich I, Petrikovics I, Szilasi M. (2009) Physiochemical characterization of stealth liposomes encapsulating an organophosphate hydrolyzing enzyme. J Lipsome Res. 23:1-6.  Abstract

Falenski KW, Carter DS, Harrison AJ, Martin BR, Blair RE, DeLorenzo RJ. (2009) Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus. Brain Res. [Epub ahead of print]  Abstract 

Fawcett WP, Aracava Y, Adler M, Pereira EF, Albuquerque EX. (2009) Acute toxicity of organophosphorus compounds in guinea pigs is sex and age dependent and cannot be solely accounted by acetycholinesterase inhibition. J Pharmacol Exp Ther. 328(2): 516-24.  Abstract

Li H, Ricordel I, Tong L, Schopfer LM, Baud F, Megarbane B, Maury E, Masson P, Lockridge O. (2009) Carbofuran poisoning detected by mass spectrometry of butyrylcholinesterase adduct in human serum. J Appl Toxicol. 29(2): 149-55.  Abstract

Li B, Schopfer LM, Grigoryan H, Thompson CM, Hinrichs SH, Masson P, Lockridge O. (2009) Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine. Toxicol Sci 107(1): 144-55.  Abstract

Qashu F, Figueiredo TH, Aroniadou-Anderjaska V, Apland, JP, Braga MF. (2009) Diazepam administration after prolonged status epilepticus reduces neurodegeneration in the amygdala but not in the hippocampus during epileptogenesis.  Amino Acids [Epub ahead of print]  Abstract

 

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Vesicating Agents (e.g. sulfur mustard)

Day BJ. (2009) Catalase and glutathione peroxidase mimics. Biochem Pharmacol. 77(3): 285-96. Abstract

Gerecke DR, Chen M, Isukapalli SS, Gordon MK, Chang YC, Tong W, Androulakis IP, Georgopoulos PG. (2009) Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect. Toxicol Appl Pharmacol. 234(2): 156-65.  Abstract

Gould N, White CW, Day BJ. (2009) A role for mitochondrial oxidative stress in sulfur mustard analog CEES-induced lung cell injury and antioxidant protection.  J Pharmacol Exp Ther  328(3): 732-9.  Abstract

Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R. (2009) Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide (CEES)-induced skin injury in SKH-1 hairless mice. Toxicol Sci. 108(1): 194-206.  Abstract

 

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Pulmonary Agents (e.g. chlorine, bromine, etc.)

Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor M, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, Korfhagen TR, Hardie WD, Bachurski CJ, Leikauf GD. (2009) Surfactant associated protein B is critical to survival in nickel-induced injury in mice. Am J Respir Cell Mol Biol. [Epub ahead of print]  Abstract

Bessac BF, Sivula M, von Hehn CA, Caceres AI, Escalera J, Jordt SE. (2008) Transient receptor potential ankyrin 1 antagonist block the noxious effects of toxic industrial isocyanates and tear gases. FASEB J. 23(4):1102-14.  Abstract

Chen L, Song W, Davis IC, Shrestha K, Schwiebert E, Sullender WM, Matalon S. (2008) Inhibition of Na+ transport in lung epithelial cells by respiratory syncytial virus infection. Am J Respir Cell Mol Biol. 40(5):588-600.  Abstract

Ganguly K, Depner M, Fattman C, Bein K, Oury TD, Wesselkamper SC, Borchers MT, Schreiber M, Gao F, Mutius EV, Kabesch M, Leikauf GD, Schulz H. (2009) Superoxide dismutase 3, extracellular (SOD3) variants and lung function. Physiol Genomics. [Epub ahead of print]  Abstract

Ji HL, Song W, Gao Z, Su XF, Nie HG, Jiang Y, Peng JB, He YX, Liao Y, Zhou YJ, Tousson A, Matalon S. (2009) SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms. Am J Physiol Lung Cell Mol Physiol. 296(3): L372-83.  Abstract

Lazrak A, Nita I, Subramaniyam D, Wei S, Song W, Ji H, Janciauskiene S, Matalon S. (2009) Alpha1-antitrypsin inhibits epithelial Na+ transport in vitro and in vivo. Am J Respir Cell Mol Biol. [Epub ahead of print] Abstract

Matalon S, Shrestha K, Kirk M, Waldheuser S, McDonald B, Smith K, Gao Z, Belaaouaj A, Crouch EC. (2009) Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo. FASEB J. [Epub ahead of print]  Abstract

Sartor MA, Leikauf GD, Medvedovic M. (2009) LRpath: A logistic regression approach for identifying enriched biological groups in gene expression data. Bioinformatics 25(2):211-7.  Abstract

Song W, Liu G, Bosworth CA, Walker JR, Megaw GA, Lazrak A, Abraham E, Sullender WM, Matalon S. (2009) Respiratory syncytial virus inhibits lung ENaC by upregulating iNOS. J Biol Chem. 284(11): 7294-306.  Abstract

Vitturi DA, Teng X, Toledo JC, Matalon S, Lancaster Jr J, Patel, RP. (2009) Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation. Am J Physiol Heart Circ Physiol. [Epub ahead of print]  Abstract

 

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Metabolic/Cellular Toxins (e.g. cyanide)

Wang W, Fridman A, Blackledge W, Connelly S, Wilson IA, Pilz RB, Boss GR. (2009) The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis. J Biol Chem. 284(6): 3521-8.  Abstract

 

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Paralytic Neurotoxins (e.g. scorpion toxins)

 

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Diagnostics (e.g. EEG devices, OP detectors/biosensors)

Barry RC, Lin Y, Wang J, Liu G, Timchalk CA. (2009) Nanotechnology-based electrochemical sensors for biomonitoring chemical exposures. J Expo Sci Environ Epidemiol. 19(1):1-18.  Abstract

Wang H, Wang J, Choi D, Tang Z, Wu H, Lin Y. (2008) EQCM immunoassay for phosphorylated acetylcholinesterase as a biomarker for organophosphate exposures based on selective zirconia adsorption and enzyme-catalytic precipitation.  Biosens Bioelectron  24(8):2377-89.  Abstract

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(26 Total 2009 Publications)