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Development of Recombinase-Expressing ("Driver") Mouse Lines for Studying the Nervous System (U01)
Release Date: November 18, 2005
Announcement Number: RFA-MH-06-007
Application Receipt Date:
January 19, 2006
Letter of Intent Date: December 17, 2005
Funding Contact: Robert Riddle, Ph.D.
Program Area: Neurogenetics
Brief Description:
This RFA is an initiative of the NIH Blueprint for Neuroscience Research (http://neuroscienceblueprint.nih.gov), a trans-NIH
partnership to accelerate neuroscience research. Fifteen Institutes and Centers are participating in the Neuroscience Blueprint.
This RFA will be administered by the NIMH on behalf of the Neuroscience Blueprint. This funding opportunity supports the
design, creation, and characterization of recombinase-expressing C57BL/6 mouse lines to aid in studies of nervous system development
and/or function. These so-called “driver lines” should specify expression in distinct cell types and/or other useful temporospatial
expression patterns in the nervous system. Drivers with the greatest utility (such as inducibility) and relevance to neuroscience
research will be given priority. Applicants should have the capability to create and validate a minimum of 10 novel driver
lines in the funding period specified.
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