NINDS Neuroscience Funding Announcements

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Neurobiology of Persistent Pain Mediated by the Trigeminal Nerve
Release Date: September 16, 2003
Announcement Number: PA-03-173
Application Receipt Date:
October 1, 2003
February 1, 2004
June 1, 2004
October 1, 2004
February 1, 2005
June 1, 2005
October 1, 2005
June 1, 2006   

Funding Contact: Linda Porter, Ph.D.
Program Area: Systems and Cognitive Neuroscience

Brief Description:
The National Institute of Neurological Disorders and Stroke (NINDS), along with the National Institute of Dental and Craniofacial Research (NIDCR), invite applications to advance our understanding of the neurobiology of persistent pain mediated by the trigeminal nerve and to develop effective therapeutic strategies to alleviate pain associated with disorders of myofascial, nervous, or skeletal tissues of the head and face, which are innervated by this nerve. The purpose of this initiative is to foster research that addresses the mechanisms of pain onset, chronic pain conditions, and responsiveness to pain therapy through novel basic and clinical research. Current knowledge of the neurobiology and neurochemistry of nociception, pain modulation and pain perception needs to be further developed and correlated with clinical manifestations of craniofacial pain to improve therapeutic strategies. This Program Announcement with Set-Aside funds (PAS) contributes to the goals of the NIH Pain Consortium, which is co- chaired by NINDS, NIDCR, and the National Institute of Nursing Research (NINR).

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