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Volume 5(3);  March 2009
Opinion
New Disturbing Trend in Antimicrobial Resistance of Gram-Negative Pathogens
Jung Hun Lee, Seok Hoon Jeong, Sun-Shin Cha, and Sang Hee Lee
PLoS Pathog. 2009 March; 5(3): e1000221. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000221.
PMCID: PMC2654509
Review
Where Are All the Mycobacterium avium Subspecies paratuberculosis in Patients with Crohn's Disease?
Ellen S. Pierce
PLoS Pathog. 2009 March; 5(3): e1000234. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000234.
PMCID: PMC2654961
Research Articles
Functional Analysis of the Leading Malaria Vaccine Candidate AMA-1 Reveals an Essential Role for the Cytoplasmic Domain in the Invasion Process
Moritz Treeck, Sonja Zacherl, Susann Herrmann, Ana Cabrera, Maya Kono, Nicole S. Struck, Klemens Engelberg, Silvia Haase, Friedrich Frischknecht, Kota Miura, Tobias Spielmann, and Tim W. Gilberger
PLoS Pathog. 2009 March; 5(3): e1000322. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000322.
PMCID: PMC2654807
A Discontinuous RNA Platform Mediates RNA Virus Replication: Building an Integrated Model for RNA–based Regulation of Viral Processes
Baodong Wu, Judit Pogany, Hong Na, Beth L. Nicholson, Peter D. Nagy, and K. Andrew White
PLoS Pathog. 2009 March; 5(3): e1000323. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000323.
PMCID: PMC2648310
KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA
Fang Cheng, Magdalena Weidner-Glunde, Markku Varjosalo, Eeva-Marja Rainio, Anne Lehtonen, Thomas F. Schulz, Päivi J. Koskinen, Jussi Taipale, and Päivi M. Ojala
PLoS Pathog. 2009 March; 5(3): e1000324. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000324.
PMCID: PMC2648312
The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling
Silvia Rossi Paccani, Marisa Benagiano, Nagaja Capitani, Irene Zornetta, Daniel Ladant, Cesare Montecucco, Mario M. D'Elios, and Cosima T. Baldari
PLoS Pathog. 2009 March; 5(3): e1000325. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000325.
PMCID: PMC2643477
A Chromosomally Encoded Virulence Factor Protects the Lyme Disease Pathogen against Host-Adaptive Immunity
Xiuli Yang, Adam S. Coleman, Juan Anguita, and Utpal Pal
PLoS Pathog. 2009 March; 5(3): e1000326. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000326.
PMCID: PMC2644780
The SET Complex Acts as a Barrier to Autointegration of HIV-1
Nan Yan, Peter Cherepanov, Janet E. Daigle, Alan Engelman, and Judy Lieberman
PLoS Pathog. 2009 March; 5(3): e1000327. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000327.
PMCID: PMC2644782
Identification of Rhoptry Trafficking Determinants and Evidence for a Novel Sorting Mechanism in the Malaria Parasite Plasmodium falciparum
Dave Richard, Lev M. Kats, Christine Langer, Casilda G. Black, Khosse Mitri, Justin A. Boddey, Alan F. Cowman, and Ross L. Coppel
PLoS Pathog. 2009 March; 5(3): e1000328. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000328.
PMCID: PMC2648313
Cholesterol-Dependent Anaplasma phagocytophilum Exploits the Low-Density Lipoprotein Uptake Pathway
Qingming Xiong, Mingqun Lin, and Yasuko Rikihisa
PLoS Pathog. 2009 March; 5(3): e1000329. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000329.
PMCID: PMC2654415
RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1
Hendrik Huthoff, Flavia Autore, Sarah Gallois-Montbrun, Franca Fraternali, and Michael H. Malim
PLoS Pathog. 2009 March; 5(3): e1000330. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000330.
PMCID: PMC2646141
Enhanced Fusion Pore Expansion Mediated by the Trans-Acting Endodomain of the Reovirus FAST Proteins
Deniz Top, Chris Barry, Trina Racine, Chelsey Louise Ellis, and Roy Duncan
PLoS Pathog. 2009 March; 5(3): e1000331. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000331.
PMCID: PMC2646142
Kaposi's Sarcoma-Associated Herpesvirus ORF45 Interacts with Kinesin-2 Transporting Viral Capsid-Tegument Complexes along Microtubules
Narayanan Sathish, Fan Xiu Zhu, and Yan Yuan
PLoS Pathog. 2009 March; 5(3): e1000332. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000332.
PMCID: PMC2647735
Activation of Host Translational Control Pathways by a Viral Developmental Switch
Carolina Arias, Derek Walsh, Jack Harbell, Angus C. Wilson, and Ian Mohr
PLoS Pathog. 2009 March; 5(3): e1000334. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000334.
PMCID: PMC2652079
Caspar Controls Resistance to Plasmodium falciparum in Diverse Anopheline Species
Lindsey S. Garver, Yuemei Dong, and George Dimopoulos
PLoS Pathog. 2009 March; 5(3): e1000335. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000335.
PMCID: PMC2647737
Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders
Ajay Singh, Alfred Orina Isaac, Xiu Luo, Maradumane L. Mohan, Mark L. Cohen, Fusong Chen, Qingzhong Kong, Jason Bartz, and Neena Singh
PLoS Pathog. 2009 March; 5(3): e1000336. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000336.
PMCID: PMC2652663
Natural Transformation of Helicobacter pylori Involves the Integration of Short DNA Fragments Interrupted by Gaps of Variable Size
Edward A. Lin, Xue-Song Zhang, Steven M. Levine, Steven R. Gill, Daniel Falush, and Martin J. Blaser
PLoS Pathog. 2009 March; 5(3): e1000337. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000337.
PMCID: PMC2650093
The Tetraspanin Protein CD37 Regulates IgA Responses and Anti-Fungal Immunity
Annemiek B. van Spriel, Mariam Sofi, Kate H. Gartlan, Alie van der Schaaf, Ineke Verschueren, Ruurd Torensma, Reinier A. P. Raymakers, Bruce E. Loveland, Mihai G. Netea, Gosse J. Adema, Mark D. Wright, and Carl G. Figdor
PLoS Pathog. 2009 March; 5(3): e1000338. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000338.
PMCID: PMC2650281
The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPXnL Late Domains to Recruit the Cellular Machinery Necessary for Viral Budding
Vincent Dussupt, Melodi P. Javid, Georges Abou-Jaoudé, Joshua A. Jadwin, Jason de La Cruz, Kunio Nagashima, and Fadila Bouamr
PLoS Pathog. 2009 March; 5(3): e1000339. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000339.
PMCID: PMC2651531
Definition of Herpes Simplex Virus Type 1 Helper Activities for Adeno-Associated Virus Early Replication Events
Nathalie Alazard-Dany, Armel Nicolas, Aurélie Ploquin, Regina Strasser, Anna Greco, Alberto L. Epstein, Cornel Fraefel, and Anna Salvetti
PLoS Pathog. 2009 March; 5(3): e1000340. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000340.
PMCID: PMC2650098
An Epstein-Barr Virus Anti-Apoptotic Protein Constitutively Expressed in Transformed Cells and Implicated in Burkitt Lymphomagenesis: The Wp/BHRF1 Link
Gemma L. Kelly, Heather M. Long, Julianna Stylianou, Wendy A. Thomas, Alison Leese, Andrew I. Bell, Georg W. Bornkamm, Josef Mautner, Alan B. Rickinson, and Martin Rowe
PLoS Pathog. 2009 March; 5(3): e1000341. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000341.
PMCID: PMC2652661
Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells
Masakazu Kamata, Yoshiko Nagaoka, and Irvin S. Y. Chen
PLoS Pathog. 2009 March; 5(3): e1000342. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000342.
PMCID: PMC2652112
Wolbachia-Mediated Cytoplasmic Incompatibility Is Associated with Impaired Histone Deposition in the Male Pronucleus
Frédéric Landmann, Guillermo A. Orsi, Benjamin Loppin, and William Sullivan
PLoS Pathog. 2009 March; 5(3): e1000343. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000343.
PMCID: PMC2652114
Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis
Katherine C. Yam, Igor D'Angelo, Rainer Kalscheuer, Haizhong Zhu, Jian-Xin Wang, Victor Snieckus, Lan H. Ly, Paul J. Converse, William R. Jacobs, Jr., Natalie Strynadka, and Lindsay D. Eltis
PLoS Pathog. 2009 March; 5(3): e1000344. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000344.
PMCID: PMC2652662
Gag Mutations Strongly Contribute to HIV-1 Resistance to Protease Inhibitors in Highly Drug-Experienced Patients besides Compensating for Fitness Loss
Elisabeth Dam, Romina Quercia, Bärbel Glass, Diane Descamps, Odile Launay, Xavier Duval, Hans-Georg Kräusslich, Allan J. Hance, François Clavel, and ANRS 109 Study Group
PLoS Pathog. 2009 March; 5(3): e1000345. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000345.
PMCID: PMC2652074
Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens
Matthew T. G. Holden, Zoe Heather, Romain Paillot, Karen F. Steward, Katy Webb, Fern Ainslie, Thibaud Jourdan, Nathalie C. Bason, Nancy E. Holroyd, Karen Mungall, Michael A. Quail, Mandy Sanders, Mark Simmonds, David Willey, Karen Brooks, David M. Aanensen, Brian G. Spratt, Keith A. Jolley, Martin C. J. Maiden, Michael Kehoe, Neil Chanter, Stephen D. Bentley, Carl Robinson, Duncan J. Maskell, Julian Parkhill, and Andrew S. Waller
PLoS Pathog. 2009 March; 5(3): e1000346. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000346.
PMCID: PMC2654543
Bim and Bmf Synergize To Induce Apoptosis in Neisseria Gonorrhoeae Infection
Oliver Kepp, Kathleen Gottschalk, Yuri Churin, Krishnaraj Rajalingam, Volker Brinkmann, Nikolaus Machuy, Guido Kroemer, and Thomas Rudel
PLoS Pathog. 2009 March; 5(3): e1000348. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000348.
PMCID: PMC2654407
Severe Plasmodium falciparum Malaria Is Associated with Circulating Ultra-Large von Willebrand Multimers and ADAMTS13 Inhibition
Deirdre Larkin, Bas de Laat, P. Vince Jenkins, James Bunn, Alister G. Craig, Virginie Terraube, Roger J. S. Preston, Cynthia Donkor, George E. Grau, Jan A. van Mourik, and James S. O'Donnell
PLoS Pathog. 2009 March; 5(3): e1000349. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000349.
PMCID: PMC2652105
Cross-Protective Potential of a Novel Monoclonal Antibody Directed against Antigenic Site B of the Hemagglutinin of Influenza A Viruses
Reiko Yoshida, Manabu Igarashi, Hiroichi Ozaki, Noriko Kishida, Daisuke Tomabechi, Hiroshi Kida, Kimihito Ito, and Ayato Takada
PLoS Pathog. 2009 March; 5(3): e1000350. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000350.
PMCID: PMC2652660
An Amphipathic α-Helix Controls Multiple Roles of Brome Mosaic Virus Protein 1a in RNA Replication Complex Assembly and Function
Ling Liu, William M. Westler, Johan A. den Boon, Xiaofeng Wang, Arturo Diaz, H. Adam Steinberg, and Paul Ahlquist
PLoS Pathog. 2009 March; 5(3): e1000351. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000351.
PMCID: PMC2654722
De Novo Synthesis of VP16 Coordinates the Exit from HSV Latency In Vivo
Richard L. Thompson, Chris M. Preston, and Nancy M. Sawtell
PLoS Pathog. 2009 March; 5(3): e1000352. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000352.
PMCID: PMC2654966
β-Lactam Resistance Response Triggered by Inactivation of a Nonessential Penicillin-Binding Protein
Bartolomé Moya, Andreas Dötsch, Carlos Juan, Jesús Blázquez, Laura Zamorano, Susanne Haussler, and Antonio Oliver
PLoS Pathog. 2009 March; 5(3): e1000353. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000353.
PMCID: PMC2654508
Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix
Luyan Ma, Matthew Conover, Haiping Lu, Matthew R. Parsek, Kenneth Bayles, and Daniel J. Wozniak
PLoS Pathog. 2009 March; 5(3): e1000354. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000354.
PMCID: PMC2654510
Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes
Silvia Stockinger, Renate Kastner, Elisabeth Kernbauer, Andreas Pilz, Sandra Westermayer, Benjamin Reutterer, Didier Soulat, Gabriele Stengl, Claus Vogl, Theresa Frenz, Zoe Waibler, Tadatsugu Taniguchi, Thomas Rülicke, Ulrich Kalinke, Mathias Müller, and Thomas Decker
PLoS Pathog. 2009 March; 5(3): e1000355. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000355.
PMCID: PMC2654726
Methylation-Dependent Binding of the Epstein-Barr Virus BZLF1 Protein to Viral Promoters
Sarah J. Dickerson, Yongna Xing, Amanda R. Robinson, William T. Seaman, Henri Gruffat, and Shannon C. Kenney
PLoS Pathog. 2009 March; 5(3): e1000356. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000356.
PMCID: PMC2654727
Seroepidemiology of Human Polyomaviruses
Jaime M. Kean, Suchitra Rao, Michael Wang, and Robert L. Garcea
PLoS Pathog. 2009 March; 5(3): e1000363. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000363.
PMCID: PMC2655709
Correction
Correction: Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3
Michal Potempa, Jan Potempa, Tomasz Kantyka, Ky-Anh Nguyen, Katarzyna Wawrzonek, Surya P. Manandhar, Katarzyna Popadiak, Kristian Riesbeck, Sigrun Eick, and Anna M. Blom
PLoS Pathog. 2009 March; 5(3): 10.1371/annotation/e82f810e-738a-47e5-9295-5a0cc9a0dc6c. Published online 2009 March 10. doi: 10.1371/annotation/e82f810e-738a-47e5-9295-5a0cc9a0dc6c.
PMCID: PMC2665013
Corrects: Michal Potempa, et al. Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3. PLoS Pathog. 2009 February; 5(2): e1000316.
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