| | This journal provides immediate access to some articles. Opinion New Disturbing Trend in Antimicrobial Resistance of Gram-Negative Pathogens Jung Hun Lee, Seok Hoon Jeong, Sun-Shin Cha, and Sang Hee Lee PLoS Pathog. 2009 March; 5(3): e1000221. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000221.PMCID: PMC2654509 Review Where Are All the Mycobacterium avium Subspecies paratuberculosis in Patients with Crohn's Disease? Ellen S. Pierce PLoS Pathog. 2009 March; 5(3): e1000234. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000234.PMCID: PMC2654961 Research Articles Functional Analysis of the Leading Malaria Vaccine Candidate AMA-1 Reveals an Essential Role for the Cytoplasmic Domain in the Invasion Process Moritz Treeck, Sonja Zacherl, Susann Herrmann, Ana Cabrera, Maya Kono, Nicole S. Struck, Klemens Engelberg, Silvia Haase, Friedrich Frischknecht, Kota Miura, Tobias Spielmann, and Tim W. Gilberger PLoS Pathog. 2009 March; 5(3): e1000322. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000322.PMCID: PMC2654807 A Discontinuous RNA Platform Mediates RNA Virus Replication: Building an Integrated Model for RNA–based Regulation of Viral Processes Baodong Wu, Judit Pogany, Hong Na, Beth L. Nicholson, Peter D. Nagy, and K. Andrew White PLoS Pathog. 2009 March; 5(3): e1000323. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000323.PMCID: PMC2648310 KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA Fang Cheng, Magdalena Weidner-Glunde, Markku Varjosalo, Eeva-Marja Rainio, Anne Lehtonen, Thomas F. Schulz, Päivi J. Koskinen, Jussi Taipale, and Päivi M. Ojala PLoS Pathog. 2009 March; 5(3): e1000324. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000324.PMCID: PMC2648312 The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling Silvia Rossi Paccani, Marisa Benagiano, Nagaja Capitani, Irene Zornetta, Daniel Ladant, Cesare Montecucco, Mario M. D'Elios, and Cosima T. Baldari PLoS Pathog. 2009 March; 5(3): e1000325. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000325.PMCID: PMC2643477 A Chromosomally Encoded Virulence Factor Protects the Lyme Disease Pathogen against Host-Adaptive Immunity Xiuli Yang, Adam S. Coleman, Juan Anguita, and Utpal Pal PLoS Pathog. 2009 March; 5(3): e1000326. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000326.PMCID: PMC2644780 The SET Complex Acts as a Barrier to Autointegration of HIV-1 Nan Yan, Peter Cherepanov, Janet E. Daigle, Alan Engelman, and Judy Lieberman PLoS Pathog. 2009 March; 5(3): e1000327. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000327.PMCID: PMC2644782 Identification of Rhoptry Trafficking Determinants and Evidence for a Novel Sorting Mechanism in the Malaria Parasite Plasmodium falciparum Dave Richard, Lev M. Kats, Christine Langer, Casilda G. Black, Khosse Mitri, Justin A. Boddey, Alan F. Cowman, and Ross L. Coppel PLoS Pathog. 2009 March; 5(3): e1000328. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000328.PMCID: PMC2648313 Cholesterol-Dependent Anaplasma phagocytophilum Exploits the Low-Density Lipoprotein Uptake Pathway Qingming Xiong, Mingqun Lin, and Yasuko Rikihisa PLoS Pathog. 2009 March; 5(3): e1000329. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000329.PMCID: PMC2654415 RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1 Hendrik Huthoff, Flavia Autore, Sarah Gallois-Montbrun, Franca Fraternali, and Michael H. Malim PLoS Pathog. 2009 March; 5(3): e1000330. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000330.PMCID: PMC2646141 Enhanced Fusion Pore Expansion Mediated by the Trans-Acting Endodomain of the Reovirus FAST Proteins Deniz Top, Chris Barry, Trina Racine, Chelsey Louise Ellis, and Roy Duncan PLoS Pathog. 2009 March; 5(3): e1000331. Published online 2009 March 6. doi: 10.1371/journal.ppat.1000331.PMCID: PMC2646142 Kaposi's Sarcoma-Associated Herpesvirus ORF45 Interacts with Kinesin-2 Transporting Viral Capsid-Tegument Complexes along Microtubules Narayanan Sathish, Fan Xiu Zhu, and Yan Yuan PLoS Pathog. 2009 March; 5(3): e1000332. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000332.PMCID: PMC2647735 Activation of Host Translational Control Pathways by a Viral Developmental Switch Carolina Arias, Derek Walsh, Jack Harbell, Angus C. Wilson, and Ian Mohr PLoS Pathog. 2009 March; 5(3): e1000334. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000334.PMCID: PMC2652079 Caspar Controls Resistance to Plasmodium falciparum in Diverse Anopheline Species Lindsey S. Garver, Yuemei Dong, and George Dimopoulos PLoS Pathog. 2009 March; 5(3): e1000335. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000335.PMCID: PMC2647737 Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders Ajay Singh, Alfred Orina Isaac, Xiu Luo, Maradumane L. Mohan, Mark L. Cohen, Fusong Chen, Qingzhong Kong, Jason Bartz, and Neena Singh PLoS Pathog. 2009 March; 5(3): e1000336. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000336.PMCID: PMC2652663 Natural Transformation of Helicobacter pylori Involves the Integration of Short DNA Fragments Interrupted by Gaps of Variable Size Edward A. Lin, Xue-Song Zhang, Steven M. Levine, Steven R. Gill, Daniel Falush, and Martin J. Blaser PLoS Pathog. 2009 March; 5(3): e1000337. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000337.PMCID: PMC2650093 The Tetraspanin Protein CD37 Regulates IgA Responses and Anti-Fungal Immunity Annemiek B. van Spriel, Mariam Sofi, Kate H. Gartlan, Alie van der Schaaf, Ineke Verschueren, Ruurd Torensma, Reinier A. P. Raymakers, Bruce E. Loveland, Mihai G. Netea, Gosse J. Adema, Mark D. Wright, and Carl G. Figdor PLoS Pathog. 2009 March; 5(3): e1000338. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000338.PMCID: PMC2650281 The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPXnL Late Domains to Recruit the Cellular Machinery Necessary for Viral Budding Vincent Dussupt, Melodi P. Javid, Georges Abou-Jaoudé, Joshua A. Jadwin, Jason de La Cruz, Kunio Nagashima, and Fadila Bouamr PLoS Pathog. 2009 March; 5(3): e1000339. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000339.PMCID: PMC2651531 Definition of Herpes Simplex Virus Type 1 Helper Activities for Adeno-Associated Virus Early Replication Events Nathalie Alazard-Dany, Armel Nicolas, Aurélie Ploquin, Regina Strasser, Anna Greco, Alberto L. Epstein, Cornel Fraefel, and Anna Salvetti PLoS Pathog. 2009 March; 5(3): e1000340. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000340.PMCID: PMC2650098 An Epstein-Barr Virus Anti-Apoptotic Protein Constitutively Expressed in Transformed Cells and Implicated in Burkitt Lymphomagenesis: The Wp/BHRF1 Link Gemma L. Kelly, Heather M. Long, Julianna Stylianou, Wendy A. Thomas, Alison Leese, Andrew I. Bell, Georg W. Bornkamm, Josef Mautner, Alan B. Rickinson, and Martin Rowe PLoS Pathog. 2009 March; 5(3): e1000341. Published online 2009 March 13. doi: 10.1371/journal.ppat.1000341.PMCID: PMC2652661 Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells Masakazu Kamata, Yoshiko Nagaoka, and Irvin S. Y. Chen PLoS Pathog. 2009 March; 5(3): e1000342. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000342.PMCID: PMC2652112 Wolbachia-Mediated Cytoplasmic Incompatibility Is Associated with Impaired Histone Deposition in the Male Pronucleus Frédéric Landmann, Guillermo A. Orsi, Benjamin Loppin, and William Sullivan PLoS Pathog. 2009 March; 5(3): e1000343. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000343.PMCID: PMC2652114 Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis Katherine C. Yam, Igor D'Angelo, Rainer Kalscheuer, Haizhong Zhu, Jian-Xin Wang, Victor Snieckus, Lan H. Ly, Paul J. Converse, William R. Jacobs, Jr., Natalie Strynadka, and Lindsay D. Eltis PLoS Pathog. 2009 March; 5(3): e1000344. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000344.PMCID: PMC2652662 Gag Mutations Strongly Contribute to HIV-1 Resistance to Protease Inhibitors in Highly Drug-Experienced Patients besides Compensating for Fitness Loss Elisabeth Dam, Romina Quercia, Bärbel Glass, Diane Descamps, Odile Launay, Xavier Duval, Hans-Georg Kräusslich, Allan J. Hance, François Clavel, and ANRS 109 Study Group PLoS Pathog. 2009 March; 5(3): e1000345. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000345.PMCID: PMC2652074 Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens Matthew T. G. Holden, Zoe Heather, Romain Paillot, Karen F. Steward, Katy Webb, Fern Ainslie, Thibaud Jourdan, Nathalie C. Bason, Nancy E. Holroyd, Karen Mungall, Michael A. Quail, Mandy Sanders, Mark Simmonds, David Willey, Karen Brooks, David M. Aanensen, Brian G. Spratt, Keith A. Jolley, Martin C. J. Maiden, Michael Kehoe, Neil Chanter, Stephen D. Bentley, Carl Robinson, Duncan J. Maskell, Julian Parkhill, and Andrew S. Waller PLoS Pathog. 2009 March; 5(3): e1000346. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000346.PMCID: PMC2654543 Bim and Bmf Synergize To Induce Apoptosis in Neisseria Gonorrhoeae Infection Oliver Kepp, Kathleen Gottschalk, Yuri Churin, Krishnaraj Rajalingam, Volker Brinkmann, Nikolaus Machuy, Guido Kroemer, and Thomas Rudel PLoS Pathog. 2009 March; 5(3): e1000348. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000348.PMCID: PMC2654407 Severe Plasmodium falciparum Malaria Is Associated with Circulating Ultra-Large von Willebrand Multimers and ADAMTS13 Inhibition Deirdre Larkin, Bas de Laat, P. Vince Jenkins, James Bunn, Alister G. Craig, Virginie Terraube, Roger J. S. Preston, Cynthia Donkor, George E. Grau, Jan A. van Mourik, and James S. O'Donnell PLoS Pathog. 2009 March; 5(3): e1000349. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000349.PMCID: PMC2652105 Cross-Protective Potential of a Novel Monoclonal Antibody Directed against Antigenic Site B of the Hemagglutinin of Influenza A Viruses Reiko Yoshida, Manabu Igarashi, Hiroichi Ozaki, Noriko Kishida, Daisuke Tomabechi, Hiroshi Kida, Kimihito Ito, and Ayato Takada PLoS Pathog. 2009 March; 5(3): e1000350. Published online 2009 March 20. doi: 10.1371/journal.ppat.1000350.PMCID: PMC2652660 An Amphipathic α-Helix Controls Multiple Roles of Brome Mosaic Virus Protein 1a in RNA Replication Complex Assembly and Function Ling Liu, William M. Westler, Johan A. den Boon, Xiaofeng Wang, Arturo Diaz, H. Adam Steinberg, and Paul Ahlquist PLoS Pathog. 2009 March; 5(3): e1000351. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000351.PMCID: PMC2654722 De Novo Synthesis of VP16 Coordinates the Exit from HSV Latency In
Vivo Richard L. Thompson, Chris M. Preston, and Nancy M. Sawtell PLoS Pathog. 2009 March; 5(3): e1000352. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000352.PMCID: PMC2654966 β-Lactam Resistance Response Triggered by Inactivation of a Nonessential Penicillin-Binding Protein Bartolomé Moya, Andreas Dötsch, Carlos Juan, Jesús Blázquez, Laura Zamorano, Susanne Haussler, and Antonio Oliver PLoS Pathog. 2009 March; 5(3): e1000353. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000353.PMCID: PMC2654508 Assembly and Development of the Pseudomonas aeruginosa Biofilm Matrix Luyan Ma, Matthew Conover, Haiping Lu, Matthew R. Parsek, Kenneth Bayles, and Daniel J. Wozniak PLoS Pathog. 2009 March; 5(3): e1000354. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000354.PMCID: PMC2654510 Characterization of the Interferon-Producing Cell in Mice Infected with Listeria monocytogenes Silvia Stockinger, Renate Kastner, Elisabeth Kernbauer, Andreas Pilz, Sandra Westermayer, Benjamin Reutterer, Didier Soulat, Gabriele Stengl, Claus Vogl, Theresa Frenz, Zoe Waibler, Tadatsugu Taniguchi, Thomas Rülicke, Ulrich Kalinke, Mathias Müller, and Thomas Decker PLoS Pathog. 2009 March; 5(3): e1000355. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000355.PMCID: PMC2654726 Methylation-Dependent Binding of the Epstein-Barr Virus BZLF1 Protein to Viral Promoters Sarah J. Dickerson, Yongna Xing, Amanda R. Robinson, William T. Seaman, Henri Gruffat, and Shannon C. Kenney PLoS Pathog. 2009 March; 5(3): e1000356. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000356.PMCID: PMC2654727 Seroepidemiology of Human Polyomaviruses Jaime M. Kean, Suchitra Rao, Michael Wang, and Robert L. Garcea PLoS Pathog. 2009 March; 5(3): e1000363. Published online 2009 March 27. doi: 10.1371/journal.ppat.1000363.PMCID: PMC2655709 Correction Correction: Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3 Michal Potempa, Jan Potempa, Tomasz Kantyka, Ky-Anh Nguyen, Katarzyna Wawrzonek, Surya P. Manandhar, Katarzyna Popadiak, Kristian Riesbeck, Sigrun Eick, and Anna M. Blom PLoS Pathog. 2009 March; 5(3): 10.1371/annotation/e82f810e-738a-47e5-9295-5a0cc9a0dc6c. Published online 2009 March 10. doi: 10.1371/annotation/e82f810e-738a-47e5-9295-5a0cc9a0dc6c.PMCID: PMC2665013 Corrects: Michal Potempa, et al. Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3. PLoS Pathog. 2009 February; 5(2): e1000316. |