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Volume 4(8);  August 2008
Opinion
HIV Vaccine Development in the Aftermath of the STEP Study: Re-Focus on Occult HIV Infection?
Klaus Überla
PLoS Pathog. 2008 August; 4(8): e1000114. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000114.
PMCID: PMC2517652
Research Articles
Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation
Caitlin O'Mahony, Paul Scully, David O'Mahony, Sharon Murphy, Frances O'Brien, Anne Lyons, Graham Sherlock, John MacSharry, Barry Kiely, Fergus Shanahan, and Liam O'Mahony
PLoS Pathog. 2008 August; 4(8): e1000112. Published online 2008 August 1. doi: 10.1371/journal.ppat.1000112.
PMCID: PMC2474968
H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice
Lucy A. Perrone, Julie K. Plowden, Adolfo García-Sastre, Jacqueline M. Katz, and Terrence M. Tumpey
PLoS Pathog. 2008 August; 4(8): e1000115. Published online 2008 August 1. doi: 10.1371/journal.ppat.1000115.
PMCID: PMC2483250
Histidine-Rich Glycoprotein Protects from Systemic Candida Infection
Victoria Rydengård, Oonagh Shannon, Katarina Lundqvist, Lukasz Kacprzyk, Anna Chalupka, Anna-Karin Olsson, Matthias Mörgelin, Willi Jahnen-Dechent, Martin Malmsten, and Artur Schmidtchen
PLoS Pathog. 2008 August; 4(8): e1000116. Published online 2008 August 1. doi: 10.1371/journal.ppat.1000116.
PMCID: PMC2537934
Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking
Karim Suwwan de Felipe, Robert T. Glover, Xavier Charpentier, O. Roger Anderson, Moraima Reyes, Christopher D. Pericone, and Howard A. Shuman
PLoS Pathog. 2008 August; 4(8): e1000117. Published online 2008 August 1. doi: 10.1371/journal.ppat.1000117.
PMCID: PMC2475511
An Erythrocyte Vesicle Protein Exported by the Malaria Parasite Promotes Tubovesicular Lipid Import from the Host Cell Surface
Pamela A. Tamez, Souvik Bhattacharjee, Christiaan van Ooij, N. Luisa Hiller, Manuel Llinás, Bharath Balu, John H. Adams, and Kasturi Haldar
PLoS Pathog. 2008 August; 4(8): e1000118. Published online 2008 August 8. doi: 10.1371/journal.ppat.1000118.
PMCID: PMC2483944
Structure of the Head of the Bartonella Adhesin BadA
Pawel Szczesny, Dirk Linke, Astrid Ursinus, Kerstin Bär, Heinz Schwarz, Tanja M. Riess, Volkhard A. J. Kempf, Andrei N. Lupas, Jörg Martin, and Kornelius Zeth
PLoS Pathog. 2008 August; 4(8): e1000119. Published online 2008 August 8. doi: 10.1371/journal.ppat.1000119.
PMCID: PMC2483945
Rudra Interrupts Receptor Signaling Complexes to Negatively Regulate the IMD Pathway
Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson, Deniz Ertürk-Hasdemir, Nicholas Paquette, and Neal Silverman
PLoS Pathog. 2008 August; 4(8): e1000120. Published online 2008 August 8. doi: 10.1371/journal.ppat.1000120.
PMCID: PMC2483946
Temperature Shift and Host Cell Contact Up-Regulate Sporozoite Expression of Plasmodium falciparum Genes Involved in Hepatocyte Infection
Anthony Siau, Olivier Silvie, Jean-François Franetich, Samir Yalaoui, Carine Marinach, Laurent Hannoun, Geert-Jaan van Gemert, Adrian J. F. Luty, Emmanuel Bischoff, Peter H. David, Georges Snounou, Catherine Vaquero, Patrick Froissard, and Dominique Mazier
PLoS Pathog. 2008 August; 4(8): e1000121. Published online 2008 August 8. doi: 10.1371/journal.ppat.1000121.
PMCID: PMC2488394
The Role of B-cells and IgM Antibodies in Parasitemia, Anemia, and VSG Switching in Trypanosoma brucei–Infected Mice
Stefan Magez, Anita Schwegmann, Robert Atkinson, Filip Claes, Michael Drennan, Patrick De Baetselier, and Frank Brombacher
PLoS Pathog. 2008 August; 4(8): e1000122. Published online 2008 August 8. doi: 10.1371/journal.ppat.1000122.
PMCID: PMC2483930
Human Cytomegalovirus UL18 Utilizes US6 for Evading the NK and T-Cell Responses
Youngkyun Kim, Boyoun Park, Sunglim Cho, Jinwook Shin, Kwangmin Cho, Youngsoo Jun, and Kwangseog Ahn
PLoS Pathog. 2008 August; 4(8): e1000123. Published online 2008 August 8. doi: 10.1371/journal.ppat.1000123.
PMCID: PMC2483941
Host Responses in Life-History Traits and Tolerance to Virus Infection in Arabidopsis thaliana
Israel Pagán, Carlos Alonso-Blanco, and Fernando García-Arenal
PLoS Pathog. 2008 August; 4(8): e1000124. Published online 2008 August 15. doi: 10.1371/journal.ppat.1000124.
PMCID: PMC2494869
Diversification of Rice Yellow Mottle Virus and Related Viruses Spans the History of Agriculture from the Neolithic to the Present
Denis Fargette, Agnès Pinel-Galzi, Drissa Sérémé, Séverine Lacombe, Eugénie Hébrard, Oumar Traoré, and Gnissa Konaté
PLoS Pathog. 2008 August; 4(8): e1000125. Published online 2008 August 15. doi: 10.1371/journal.ppat.1000125.
PMCID: PMC2495034
Vesicular Egress of Non-Enveloped Lytic Parvoviruses Depends on Gelsolin Functioning
Séverine Bär, Laurent Daeffler, Jean Rommelaere, and Jürg P. F. Nüesch
PLoS Pathog. 2008 August; 4(8): e1000126. Published online 2008 August 15. doi: 10.1371/journal.ppat.1000126.
PMCID: PMC2494870
Evidence of Infection by H5N2 Highly Pathogenic Avian Influenza Viruses in Healthy Wild Waterfowl
Nicolas Gaidet, Giovanni Cattoli, Saliha Hammoumi, Scott H. Newman, Ward Hagemeijer, John Y. Takekawa, Julien Cappelle, Tim Dodman, Tony Joannis, Patricia Gil, Isabella Monne, Alice Fusaro, Ilaria Capua, Shiiwuua Manu, Pierfrancesco Micheloni, Ulf Ottosson, John H. Mshelbwala, Juan Lubroth, Joseph Domenech, and François Monicat
PLoS Pathog. 2008 August; 4(8): e1000127. Published online 2008 August 15. doi: 10.1371/journal.ppat.1000127.
PMCID: PMC2503949
Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis
Stephen C. Graham, Mohammad W. Bahar, Samantha Cooray, Ron A.-J. Chen, Daniel M. Whalen, Nicola G. A. Abrescia, David Alderton, Raymond J. Owens, David I. Stuart, Geoffrey L. Smith, and Jonathan M. Grimes
PLoS Pathog. 2008 August; 4(8): e1000128. Published online 2008 August 15. doi: 10.1371/journal.ppat.1000128.
PMCID: PMC2494871
Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction
Pål Stenmark, Jérôme Dupuy, Akihiro Imamura, Makoto Kiso, and Raymond C. Stevens
PLoS Pathog. 2008 August; 4(8): e1000129. Published online 2008 August 15. doi: 10.1371/journal.ppat.1000129.
PMCID: PMC2493045
Evolutionary and Transmission Dynamics of Reassortant H5N1 Influenza Virus in Indonesia
Tommy Tsan-Yuk Lam, Chung-Chau Hon, Oliver G. Pybus, Sergei L. Kosakovsky Pond, Raymond Tze-Yeung Wong, Chi-Wai Yip, Fanya Zeng, and Frederick Chi-Ching Leung
PLoS Pathog. 2008 August; 4(8): e1000130. Published online 2008 August 22. doi: 10.1371/journal.ppat.1000130.
PMCID: PMC2515348
HIV-1 Nef Targets MHC-I and CD4 for Degradation Via a Final Common β-COP–Dependent Pathway in T Cells
Malinda R. Schaefer, Elizabeth R. Wonderlich, Jeremiah F. Roeth, Jolie A. Leonard, and Kathleen L. Collins
PLoS Pathog. 2008 August; 4(8): e1000131. Published online 2008 August 22. doi: 10.1371/journal.ppat.1000131.
PMCID: PMC2515349
Bacillus anthracis Secretes Proteins That Mediate Heme Acquisition from Hemoglobin
Anthony W. Maresso, Gabriella Garufi, and Olaf Schneewind
PLoS Pathog. 2008 August; 4(8): e1000132. Published online 2008 August 22. doi: 10.1371/journal.ppat.1000132.
PMCID: PMC2515342
Molecular Epidemiology of A/H3N2 and A/H1N1 Influenza Virus during a Single Epidemic Season in the United States
Martha I. Nelson, Laurel Edelman, David J. Spiro, Alex R. Boyne, Jayati Bera, Rebecca Halpin, Elodie Ghedin, Mark A. Miller, Lone Simonsen, Cecile Viboud, and Edward C. Holmes
PLoS Pathog. 2008 August; 4(8): e1000133. Published online 2008 August 22. doi: 10.1371/journal.ppat.1000133.
PMCID: PMC2495036
HIV Traffics through a Specialized, Surface-Accessible Intracellular Compartment during trans-Infection of T Cells by Mature Dendritic Cells
Hyun Jae Yu, Morgan A. Reuter, and David McDonald
PLoS Pathog. 2008 August; 4(8): e1000134. Published online 2008 August 22. doi: 10.1371/journal.ppat.1000134.
PMCID: PMC2515344
Viral Paratransgenesis in the Malaria Vector Anopheles gambiae
Xiaoxia Ren, Egbert Hoiczyk, and Jason L. Rasgon
PLoS Pathog. 2008 August; 4(8): e1000135. Published online 2008 August 22. doi: 10.1371/journal.ppat.1000135.
PMCID: PMC2500179
Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
Franck Tarendeau, Thibaut Crepin, Delphine Guilligay, Rob W. H. Ruigrok, Stephen Cusack, and Darren J. Hart
PLoS Pathog. 2008 August; 4(8): e1000136. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000136.
PMCID: PMC2515345
A C-Terminal Protease-Resistant Prion Fragment Distinguishes Ovine “CH1641-Like” Scrapie from Bovine Classical and L-Type BSE in Ovine Transgenic Mice
Thierry Baron, Anna Bencsik, Johann Vulin, Anne-Gaëlle Biacabe, Eric Morignat, Jérémy Verchere, and Dominique Betemps
PLoS Pathog. 2008 August; 4(8): e1000137. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000137.
PMCID: PMC2516186
Superior Immunogenicity of Inactivated Whole Virus H5N1 Influenza Vaccine is Primarily Controlled by Toll-like Receptor Signalling
Felix Geeraedts, Nadege Goutagny, Veit Hornung, Martina Severa, Aalzen de Haan, Judith Pool, Jan Wilschut, Katherine A. Fitzgerald, and Anke Huckriede
PLoS Pathog. 2008 August; 4(8): e1000138. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000138.
PMCID: PMC2516931
Accelerated High Fidelity Prion Amplification Within and Across Prion Species Barriers
Kristi M. Green, Joaquín Castilla, Tanya S. Seward, Dana L. Napier, Jean E. Jewell, Claudio Soto, and Glenn C. Telling
PLoS Pathog. 2008 August; 4(8): e1000139. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000139.
PMCID: PMC2516356
Yersinia enterocolitica Serum Resistance Proteins YadA and Ail Bind the Complement Regulator C4b-Binding Protein
Vesa Kirjavainen, Hanna Jarva, Marta Biedzka-Sarek, Anna M. Blom, Mikael Skurnik, and Seppo Meri
PLoS Pathog. 2008 August; 4(8): e1000140. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000140.
PMCID: PMC2516929
Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus
Mohammad F. Saeed, Andrey A. Kolokoltsov, Alexander N. Freiberg, Michael R. Holbrook, and Robert A. Davey
PLoS Pathog. 2008 August; 4(8): e1000141. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000141.
PMCID: PMC2516934
XIAP Regulates Cytosol-Specific Innate Immunity to Listeria Infection
Laura D. Bauler, Colin S. Duckett, and Mary X. D. O'Riordan
PLoS Pathog. 2008 August; 4(8): e1000142. Published online 2008 August 29. doi: 10.1371/journal.ppat.1000142.
PMCID: PMC2516935
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