| | This journal provides immediate access to some articles. Accelerated Communication Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design Yechun Xu, Jacques Ph. Colletier, Hualiang Jiang, Israel Silman, Joel L. Sussman, and Martin Weik Protein Sci. 2008 April; 17(4): 601–605. doi: 10.1110/ps.083453808.PMCID: PMC2271175 Articles The epitope space of the human proteome Lisa Berglund, Jorge Andrade, Jacob Odeberg, and Mathias Uhlén Protein Sci. 2008 April; 17(4): 606–613. doi: 10.1110/ps.073347208.PMCID: PMC2271163 Design of a highly specific and noninvasive biosensor suitable for real-time in vivo imaging of mercury (II) uptake Richard R. Chapleau, Rebecca Blomberg, Peter C. Ford, and Martin Sagermann Protein Sci. 2008 April; 17(4): 614–622. doi: 10.1110/ps.073358908.PMCID: PMC2271171 Analysis of solvent content and oligomeric states in protein crystals—does symmetry matter? Maksymilian Chruszcz, Wojciech Potrzebowski, Matthew D. Zimmerman, Marek Grabowski, Heping Zheng, Piotr Lasota, and Wladek Minor Protein Sci. 2008 April; 17(4): 623–632. doi: 10.1110/ps.073360508.PMCID: PMC2271157 Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency John J. Dwyer, Karen L. Wilson, Kimberly Martin, Jennifer E. Seedorff, Aisha Hasan, Robyn J. Medinas, Donna K. Davison, Michael D. Feese, Hans-Thomas Richter, Hidong Kim, Thomas J. Matthews, and Mary K. Delmedico Protein Sci. 2008 April; 17(4): 633–643. doi: 10.1110/ps.073307608.PMCID: PMC2271165 Side chain burial and hydrophobic core packing in protein folding transition states Patrick J. Farber and Anthony Mittermaier Protein Sci. 2008 April; 17(4): 644–651. doi: 10.1110/ps.073105408.PMCID: PMC2271162 Structural and thermodynamic effects of ANS binding to human interleukin-1 receptor antagonist Ramil F. Latypov, Dingjiang Liu, Kannan Gunasekaran, Timothy S. Harvey, Vladimir I. Razinkov, and Andrei A. Raibekas Protein Sci. 2008 April; 17(4): 652–663. doi: 10.1110/ps.073332408.PMCID: PMC2271160 Substrate specificity of human kallikreins 1 and 6 determined by phage display Hai-Xin Li, Bum-Yeol Hwang, Gurunathan Laxmikanthan, Sachiko I. Blaber, Michael Blaber, Pavel A. Golubkov, Pengyu Ren, Brent L. Iverson, and George Georgiou Protein Sci. 2008 April; 17(4): 664–672. doi: 10.1110/ps.073333208.PMCID: PMC2271166 Engineering membrane protein overproduction in Escherichia coli
Daniel Martinez Molina, Tobias Cornvik, Said Eshaghi, Jesper Z. Haeggström, Pär Nordlund, and Marina Ignatushchenko Sabet Protein Sci. 2008 April; 17(4): 673–680. doi: 10.1110/ps.073242508.PMCID: PMC2271156 Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli Sergio Martinez Rodriguez, Santosh Panjikar, Karolien Van Belle, Lode Wyns, Joris Messens, and Remy Loris Protein Sci. 2008 April; 17(4): 681–690. doi: 10.1110/ps.073420708.PMCID: PMC2271172 Crystal structure of enoyl–acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor Jun Saito, Mototsugu Yamada, Takashi Watanabe, Maiko Iida, Hideo Kitagawa, Sho Takahata, Tomohiro Ozawa, Yasuo Takeuchi, and Fukuichi Ohsawa Protein Sci. 2008 April; 17(4): 691–699. doi: 10.1110/ps.073288808.PMCID: PMC2271168 The crystal structure of the C45S mutant of annelid Arenicola marina peroxiredoxin 6 supports its assignment to the mechanistically typical 2-Cys subfamily without any formation of toroid-shaped decamers Aude Smeets, Eléonore Loumaye, André Clippe, Jean-François Rees, Bernard Knoops, and Jean-Paul Declercq Protein Sci. 2008 April; 17(4): 700–710. doi: 10.1110/ps.073399308.PMCID: PMC2271159 Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities Dmitri Tolkatchev, Suneil Malik, Anna Vinogradova, Ping Wang, Zhigang Chen, Ping Xu, Hugh P.J. Bennett, Andrew Bateman, and Feng Ni Protein Sci. 2008 April; 17(4): 711–724. doi: 10.1110/ps.073295308.PMCID: PMC2271164 Structure–function studies on the active site of the coelenterazine-dependent luciferase from Renilla Jongchan Woo, Matthew H. Howell, and Albrecht G. von Arnim Protein Sci. 2008 April; 17(4): 725–735. doi: 10.1110/ps.073355508.PMCID: PMC2271170 An efficient on-column expressed protein ligation strategy: Application to segmental triple labeling of human apolipoprotein E3 Wentao Zhao, Yonghong Zhang, Chunxian Cui, Qianqian Li, and Jianjun Wang Protein Sci. 2008 April; 17(4): 736–747. doi: 10.1110/ps.073383708.PMCID: PMC2271161 Cu(II) organizes β-2-microglobulin oligomers but is released upon amyloid formation Kwasi Antwi, Maura Mahar, Rapole Srikanth, Mark R. Olbris, Julian F. Tyson, and Richard W. Vachet Protein Sci. 2008 April; 17(4): 748–759. doi: 10.1110/ps.073249008.PMCID: PMC2271169 Zn2+ binding to human calbindin D28k and the role of histidine residues Mikael C. Bauer, Hanna Nilsson, Eva Thulin, Birgitta Frohm, Johan Malm, and Sara Linse Protein Sci. 2008 April; 17(4): 760–767. doi: 10.1110/ps.073381108.PMCID: PMC2271158 Structural dependencies of protein backbone 2JNC′ couplings Nenad Juranić, J.J. Dannenberg, Gabriel Cornilescu, Pedro Salvador, Elena Atanasova, Hee-Chul Ahn, Slobodan Macura, John L. Markley, and Franklyn G. Prendergast Protein Sci. 2008 April; 17(4): 768–776. doi: 10.1110/ps.073331608.PMCID: PMC2271174 Quantitative analysis of multi-protein interactions using FRET: Application to the SUMO pathway Sarah F. Martin, Michael H. Tatham, Ronald T. Hay, and Ifor D.W. Samuel Protein Sci. 2008 April; 17(4): 777–784. doi: 10.1110/ps.073369608.PMCID: PMC2271167 Protein Structure Report NMR solution structure of KP-TerB, a tellurite-resistance protein from Klebsiella pneumoniae
Sheng-Kuo Chiang, Yuan-Chao Lou, and Chinpan Chen Protein Sci. 2008 April; 17(4): 785–789. doi: 10.1110/ps.073389408.PMCID: PMC2271173 |