pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 96(26);  December 21, 1999
Commentaries
TRP, inositol 1,4,5-trisphosphate receptors, and capacitative calcium entry
James W. Putney, Jr.
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14669–14671.
PMCID: PMC33952
Ig-like domains: Evolution from simple interaction molecules to sophisticated antigen recognition
A. Neil Barclay
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14672–14674.
PMCID: PMC33953
How many mutations does it take to make a tumor?
C. Richard Boland and Luigi Ricciardiello
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14675–14677.
PMCID: PMC33954
Varieties of imaging with scanning probe microscopes
Helen G. Hansma
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14678–14680.
PMCID: PMC33955
Physical Sciences
Applied Mathematics
Dissociation of HIV-1 from follicular dendritic cells during HAART: Mathematical analysis
William S. Hlavacek, Carla Wofsy, and Alan S. Perelson
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14681–14686.
PMCID: PMC24707
Models for stochastic climate prediction
Andrew J. Majda, Ilya Timofeyev, and Eric Vanden Eijnden
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14687–14691.
PMCID: PMC24708
A simple explanation for taxon abundance patterns
Johan Chu and Christoph Adami
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15017–15019.
PMCID: PMC24765
Chemistry
A cyclodextrin dimer with a photocleavable linker as a possible carrier for the photosensitizer in photodynamic tumor therapy
Anja Ruebner, Zhiwei Yang, David Leung, and Ronald Breslow
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14692–14693.
PMCID: PMC24709
Activity-based protein profiling: The serine hydrolases
Yongsheng Liu, Matthew P. Patricelli, and Benjamin F. Cravatt
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14694–14699.
PMCID: PMC24710
Nucleic acid duplexes incorporating a dissociable covalent base pair
Kui Gao and Leslie E. Orgel
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14837–14842.
PMCID: PMC24734
Mathematics
On the classification of binary shifts of finite commutant index
Geoffrey L. Price
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14700–14705.
PMCID: PMC24711
Biological Sciences
Biochemistry
Activity-based protein profiling: The serine hydrolases
Yongsheng Liu, Matthew P. Patricelli, and Benjamin F. Cravatt
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14694–14699.
PMCID: PMC24710
Structural details of an interaction between cardiolipin and an integral membrane protein
Katherine E. McAuley, Paul K. Fyfe, Justin P. Ridge, Neil W. Isaacs, Richard J. Cogdell, and Michael R. Jones
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14706–14711.
PMCID: PMC24712
A complex ligase ribozyme evolved in vitro from a group I ribozyme domain
Luc Jaeger, Martin C. Wright, and Gerald F. Joyce
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14712–14717.
PMCID: PMC24713
The heme-copper oxidases of Thermus thermophilus catalyze the reduction of nitric oxide: Evolutionary implications
Alessandro Giuffrè, Gottfried Stubauer, Paolo Sarti, Maurizio Brunori, Walter G. Zumft, Gerhard Buse, and Tewfik Soulimane
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14718–14723.
PMCID: PMC24714
Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: A unique signaling pathway in the steroid receptor superfamily
Yi-Fen Lee, Chih-Rong Shyr, Tin Htwe Thin, Wen-Jye Lin, and Chawnshang Chang
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14724–14729.
PMCID: PMC24715
Analysis of three structurally related antiviral compounds in complex with human rhinovirus 16
Andrea T. Hadfield, Guy D. Diana, and Michael G. Rossmann
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14730–14735.
PMCID: PMC24716
Synthetic genes for glycoprotein design and the elucidation of hydroxyproline-O-glycosylation codes
Elena Shpak, Joseph F. Leykam, and Marcia J. Kieliszewski
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14736–14741.
PMCID: PMC24717
Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells
Hao Zhu, Huawei Qiu, Hae-Won Patricia Yoon, Shuning Huang, and H. Franklin Bunn
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14742–14747.
PMCID: PMC24718
Theoretical investigation of the [1,2]-sigmatropic hydrogen migration in the mechanism of oxidation of 2-aminobenzoyl-CoA by 2-aminobenzoyl-CoA monooxygenase/reductase
Rhonda A. Torres and Thomas C. Bruice
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14748–14752.
PMCID: PMC24719
A molecular basis for nitric oxide sensing by soluble guanylate cyclase
Yunde Zhao, Philip E. Brandish, David P. Ballou, and Michael A. Marletta
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14753–14758.
PMCID: PMC24720
Crystal structure of the Sec18p N-terminal domain
S. Mariana Babor and Deborah Fass
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14759–14764.
PMCID: PMC24721
From the Cover:
A family of membrane-embedded metalloproteases involved in regulated proteolysis of membrane-associated transcription factors
David Z. Rudner, Paul Fawcett, and Richard Losick
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14765–14770.
PMCID: PMC24722
HSP70 homolog functions in cell-to-cell movement of a plant virus
Valery V. Peremyslov, Yuka Hagiwara, and Valerian V. Dolja
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14771–14776.
PMCID: PMC24723
Homospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved from deoxyhypusine synthase
Dietrich Ober and Thomas Hartmann
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14777–14782.
PMCID: PMC24724
The single minichromosome maintenance protein of Methanobacterium thermoautotrophicum ΔH contains DNA helicase activity
Zvi Kelman, Joon-Kyu Lee, and Jerard Hurwitz
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14783–14788.
PMCID: PMC24725
Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators
Dalai Yan, Ho S. Cho, Curtis A. Hastings, Michele M. Igo, Seok-Yong Lee, Jeffrey G. Pelton, Valley Stewart, David E. Wemmer, and Sydney Kustu
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14789–14794.
PMCID: PMC24726
Genomic structure and ecdysone regulation of the prophenoloxidase 1 gene in the malaria vector Anopheles gambiae
A. Ahmed, D. Martín, A. G. O. Manetti, S.-J. Han, W.-J. Lee, K. D. Mathiopoulos, H.-M. Müller, F. C. Kafatos, A. Raikhel, and P. T. Brey
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14795–14800.
PMCID: PMC24727
The α-helical FXXΦΦ motif in p53: TAF interaction and discrimination by MDM2
Motonari Uesugi and Gregory L. Verdine
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14801–14806.
PMCID: PMC24728
Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor α (RARα) and oncogenic RARα fusion proteins
Jun Zhu, Maurizio Gianni, Eliezer Kopf, Nicole Honoré, Mounira Chelbi-Alix, Marcel Koken, Frédérique Quignon, Cécile Rochette-Egly, and Hugues de Thé
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14807–14812.
PMCID: PMC24729
Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA
Matthew S. Fitzgerald, Karel Riha, Feng Gao, Shuxin Ren, Thomas D. McKnight, and Dorothy E. Shippen
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14813–14818.
PMCID: PMC24730
The MinC component of the division site selection system in Escherichia coli interacts with FtsZ to prevent polymerization
Zonglin Hu, Amit Mukherjee, Sebastien Pichoff, and Joe Lutkenhaus
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14819–14824.
PMCID: PMC24731
Acylation stabilizes a protease-resistant conformation of protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides
Sylvain Arnould, Masayuki Takahashi, and Jean-Michel Camadro
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14825–14830.
PMCID: PMC24732
Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and γFBP-B
Sophie Deltour, Cateline Guerardel, and Dominique Leprince
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14831–14836.
PMCID: PMC24733
Nucleic acid duplexes incorporating a dissociable covalent base pair
Kui Gao and Leslie E. Orgel
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14837–14842.
PMCID: PMC24734
Glucose intolerance caused by a defect in the entero-insular axis: A study in gastric inhibitory polypeptide receptor knockout mice
Kazumasa Miyawaki, Yuichiro Yamada, Hideki Yano, Hitoshi Niwa, Nobuhiro Ban, Yu Ihara, Akira Kubota, Shinpei Fujimoto, Mariko Kajikawa, Akira Kuroe, Kinsuke Tsuda, Hiroyuki Hashimoto, Tokuyuki Yamashita, Takahito Jomori, Fumi Tashiro, Jun-ichi Miyazaki, and Yutaka Seino
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14843–14847.
PMCID: PMC24735
Biophysics
Pressure-induced protein-folding/unfolding kinetics
Nathan Hillson, José Nelson Onuchic, and Angel E. García
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14848–14853.
PMCID: PMC24736
From snapshot to movie: [var phi] analysis of protein folding transition states taken one step further
Tomas Ternström, Ugo Mayor, Mikael Akke, and Mikael Oliveberg
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14854–14859.
PMCID: PMC24737
Patterned library analysis: A method for the quantitative assessment of hypotheses concerning the determinants of protein structure
Steven J. Lahr, Anne Broadwater, Charles W. Carter, Jr., Martha L. Collier, Lucinda Hensley, Jennifer C. Waldner, Gary J. Pielak, and Marshall Hall Edgell
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14860–14865.
PMCID: PMC24738
Cell Biology
Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins
James S. Hardwick, Finny G. Kuruvilla, Jeffrey K. Tong, Alykhan F. Shamji, and Stuart L. Schreiber
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14866–14870.
PMCID: PMC24739
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL
David C. S. Huang, Michael Hahne, Michael Schroeter, Karl Frei, Adriano Fontana, Andreas Villunger, Kim Newton, Juerg Tschopp, and Andreas Strasser
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14871–14876.
PMCID: PMC24740
Long-term suppression of Leydig cell steroidogenesis prevents Leydig cell aging
Haolin Chen and Barry R. Zirkin
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14877–14881.
PMCID: PMC24741
The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFα2 transcription factor
Sandra McNeil, Congmei Zeng, Kimberly S. Harrington, Scott Hiebert, Jane B. Lian, Janet L. Stein, André J. van Wijnen, and Gary S. Stein
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14882–14887.
PMCID: PMC24742
Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis
Michael Streit, Lucia Riccardi, Paula Velasco, Lawrence F. Brown, Thomas Hawighorst, Paul Bornstein, and Michael Detmar
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14888–14893.
PMCID: PMC24743
From the Cover:
Growth hormone-releasing hormone: An autocrine growth factor for small cell lung carcinoma
H. Kiaris, A. V. Schally, J. L. Varga, K. Groot, and P. Armatis
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14894–14898.
PMCID: PMC24744
DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes
Susan M. Bailey, Julianne Meyne, David J. Chen, Akihiro Kurimasa, Gloria C. Li, Bruce E. Lehnert, and Edwin H. Goodwin
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14899–14904.
PMCID: PMC24745
Intracellular localization of P1 ParB protein depends on ParA and parS
Natalie Erdmann, Tamara Petroff, and Barbara E. Funnell
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14905–14910.
PMCID: PMC24746
Interaction of the Ras-related protein associated with diabetes Rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation
Jianhua Zhu, Yu-Hua Tseng, Jason D. Kantor, Christopher J. Rhodes, Bruce R. Zetter, Julie S. Moyers, and C. Ronald Kahn
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14911–14918.
PMCID: PMC24747
Development of an in vitro reconstitution assay for glucose transporter 4 translocation
Gen Inoue, Bentley Cheatham, and C. Ronald Kahn
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14919–14924.
PMCID: PMC24748
The N-terminal 209-aa domain of high molecular- weight 4.1R isoforms abrogates 4.1R targeting to the nucleus
Carlos M. Luque, María-José Lallena, Carmen M. Pérez-Ferreiro, Yolanda de Isidro, Guillermo De Cárcer, Miguel A. Alonso, and Isabel Correas
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14925–14930.
PMCID: PMC24749
The 65-kDa carrot microtubule-associated protein forms regularly arranged filamentous cross-bridges between microtubules
Jordi Chan, Cynthia G. Jensen, Lawrence C. W. Jensen, Max Bush, and Clive W. Lloyd
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14931–14936.
PMCID: PMC24750
From the Cover:
Splicing is required for rapid and efficient mRNA export in metazoans
Ming-juan Luo and Robin Reed
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14937–14942.
PMCID: PMC24751
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival
Sarah Ogilvy, Donald Metcalf, Cristin G. Print, Mary L. Bath, Alan W. Harris, and Jerry M. Adams
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14943–14948.
PMCID: PMC24752
Defects in transforming growth factor-β signaling cooperate with a Ras oncogene to cause rapid aneuploidy and malignant transformation of mouse keratinocytes
Adam Glick, Nicholas Popescu, Valarie Alexander, Hikaru Ueno, Erwin Bottinger, and Stuart H. Yuspa
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14949–14954.
PMCID: PMC24753
Modulation of Ca2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca2+ entry
Guylain Boulay, Darren M. Brown, Ning Qin, Meisheng Jiang, Alexander Dietrich, Michael Xi Zhu, Zhangguo Chen, Mariel Birnbaumer, Katsuhiko Mikoshiba, and Lutz Birnbaumer
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14955–14960.
PMCID: PMC24754
Transforming growth factor β targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity
Hikaru Nagahara, Sergei A. Ezhevsky, Adamina M. Vocero-Akbani, Philipp Kaldis, Mark J. Solomon, and Steven F. Dowdy
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14961–14966.
PMCID: PMC24755
Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena
Brian D. Strahl, Reiko Ohba, Richard G. Cook, and C. David Allis
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14967–14972.
PMCID: PMC24756
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
Rami Khosravi, Ruth Maya, Tanya Gottlieb, Moshe Oren, Yosef Shiloh, and Dganit Shkedy
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14973–14977.
PMCID: PMC24757
Developmental Biology
Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo
George L. Fox, Ilaria Rebay, and Richard O. Hynes
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14978–14983.
PMCID: PMC24758
Mice cloned from embryonic stem cells
Teruhiko Wakayama, Ivan Rodriguez, Anthony C. F. Perry, Ryuzo Yanagimachi, and Peter Mombaerts
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14984–14989.
PMCID: PMC24759
Caenorhabditis elegans Mediator complexes are required for developmental-specific transcriptional activation
Jae Young Kwon, Jin Mo Park, Byung Soo Gim, Sang Jun Han, Junho Lee, and Young-Joon Kim
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14990–14995.
PMCID: PMC24760
X-ngnr-1 and Xath3 promote ectopic expression of sensory neuron markers in the neurula ectoderm and have distinct inducing properties in the retina
Muriel Perron, Karin Opdecamp, Karen Butler, William A. Harris, and Eric J. Bellefroid
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14996–15001.
PMCID: PMC24761
Isolated cleft palate in mice with a targeted mutation of the LIM homeobox gene Lhx8
Yangu Zhao, Yi-Jun Guo, Andreas C. Tomac, Nora R. Taylor, Alexander Grinberg, Eric J. Lee, SingPing Huang, and Heiner Westphal
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15002–15006.
PMCID: PMC24762
Evolution
Major recent and independent changes in levels and patterns of expression have occurred at the b gene, a regulatory locus in maize
David A. Selinger and Vicki L. Chandler
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15007–15012.
PMCID: PMC24763
Female choice increases offspring fitness in an arctiid moth (Utetheisa ornatrix)
Vikram K. Iyengar and Thomas Eisner
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15013–15016.
PMCID: PMC24764
A simple explanation for taxon abundance patterns
Johan Chu and Christoph Adami
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15017–15019.
PMCID: PMC24765
Genetics
Identification of transforming growth factor-β- regulated genes in Caenorhabditis elegans by differential hybridization of arrayed cDNAs
Makoto Mochii, Satoru Yoshida, Kiyokazu Morita, Yuji Kohara, and Naoto Ueno
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15020–15025.
PMCID: PMC24766
The mating-type and pathogenicity locus of the fungus Ustilago hordei spans a 500-kb region
Nancy Lee, Guus Bakkeren, Katherine Wong, John E. Sherwood, and James W. Kronstad
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15026–15031.
PMCID: PMC24767
A subset of skin tumor modifier loci determines survival time of tumor-bearing mice
Hiroki Nagase, Jian-Hua Mao, and Allan Balmain
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15032–15037.
PMCID: PMC24768
Human cells compromised for p53 function exhibit defective global and transcription-coupled nucleotide excision repair, whereas cells compromised for pRb function are defective only in global repair
Jean-Philippe Therrien, Régen Drouin, Caroline Baril, and Elliot A. Drobetsky
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15038–15043.
PMCID: PMC24769
Varying the number of telomere-bound proteins does not alter telomere length in tel1Δ cells
Alo Ray and Kurt W. Runge
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15044–15049.
PMCID: PMC24770
Immunology
Abundant empty class II MHC molecules on the surface of immature dendritic cells
Laura Santambrogio, Aaron K. Sato, Falko R. Fischer, Martin E. Dorf, and Lawrence J. Stern
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15050–15055.
PMCID: PMC24771
Extracellular antigen processing and presentation by immature dendritic cells
Laura Santambrogio, Aaron K. Sato, Gregory J. Carven, Svetlana L. Belyanskaya, Jack L. Strominger, and Lawrence J. Stern
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15056–15061.
PMCID: PMC24772
The human natural killer cell immune synapse
Daniel M. Davis, Isaac Chiu, Marlys Fassett, George B. Cohen, Ofer Mandelboim, and Jack L. Strominger
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15062–15067.
PMCID: PMC24773
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice
Hans-Reimer Rodewald, Thomas Brocker, and Corinne Haller
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15068–15073.
PMCID: PMC24774
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
Eugene D. Kwon, Barbara A. Foster, Arthur A. Hurwitz, Chris Madias, James P. Allison, Norman M. Greenberg, and Maurice B. Burg
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15074–15079.
PMCID: PMC24775
From the Cover:
A novel multigene family encodes diversified variable regions
Scott J. Strong, M. Gail Mueller, Ronda T. Litman, Noel A. Hawke, Robert N. Haire, Ann L. Miracle, Jonathan P. Rast, Chris T. Amemiya, and Gary W. Litman
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15080–15085.
PMCID: PMC24776
Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B
Le Hong Ho, Takahiro Uehara, Ching-Cheng Chen, Hiromi Kubagawa, and Max D. Cooper
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15086–15090.
PMCID: PMC24777
Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells
Chiara Vitale, Chiara Romagnani, Michela Falco, Marco Ponte, Massimo Vitale, Alessandro Moretta, Andrea Bacigalupo, Lorenzo Moretta, and Maria Cristina Mingari
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15091–15096.
PMCID: PMC24778
The human granulocyte-macrophage colony- stimulating factor gene is autonomously regulated in vivo by an inducible tissue-specific enhancer
Peter N. Cockerill, Andrew G. Bert, Donna Roberts, and Mathew A. Vadas
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15097–15102.
PMCID: PMC24779
Medical Sciences
Dissociation of HIV-1 from follicular dendritic cells during HAART: Mathematical analysis
William S. Hlavacek, Carla Wofsy, and Alan S. Perelson
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 14681–14686.
PMCID: PMC24707
A bcr-3 isoform of RARα-PML potentiates the development of PML-RARα-driven acute promyelocytic leukemia
Jessica L. Pollock, Peter Westervelt, Arun K. Kurichety, Pier Giuseppe Pelicci, Jay L. Grisolano, and Timothy J. Ley
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15103–15108.
PMCID: PMC24780
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
Richard T. Davey, Jr., Niranjan Bhat, Christian Yoder, Tae-Wook Chun, Julia A. Metcalf, Robin Dewar, Ven Natarajan, Richard A. Lempicki, Joseph W. Adelsberger, Kirk D. Miller, Joseph A. Kovacs, Michael A. Polis, Robert E. Walker, Judith Falloon, Henry Masur, Dennis Gee, Michael Baseler, Dimiter S. Dimitrov, Anthony S. Fauci, and H. Clifford Lane
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15109–15114.
PMCID: PMC24781
PEG-3, a nontransforming cancer progression gene, is a positive regulator of cancer aggressiveness and angiogenesis
Zao-Zhong Su, Neil I. Goldstein, Hongping Jiang, Mei-Nai Wang, Gregory J. Duigou, Charles S. H. Young, and Paul B. Fisher
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15115–15120.
PMCID: PMC24782
The onset and extent of genomic instability in sporadic colorectal tumor progression
Daniel L. Stoler, Neng Chen, Mark Basik, Morton S. Kahlenberg, Miguel A. Rodriguez-Bigas, Nicholas J. Petrelli, and Garth R. Anderson
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15121–15126.
PMCID: PMC24783
MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes
Tetsuo Minamino, Toshiaki Yujiri, Philip J. Papst, Edward D. Chan, Gary L. Johnson, and Naohiro Terada
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15127–15132.
PMCID: PMC24784
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
Richard H. Karas, Jeffrey B. Hodgin, Moon Kwoun, John H. Krege, Mark Aronovitz, William Mackey, Jan Åke Gustafsson, Kenneth S. Korach, Oliver Smithies, and Michael E. Mendelsohn
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15133–15136.
PMCID: PMC24785
From the Cover:
Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans
Michael R. Scott, Robert Will, James Ironside, Hoang-Oanh B. Nguyen, Patrick Tremblay, Stephen J. DeArmond, and Stanley B. Prusiner
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15137–15142.
PMCID: PMC24786
Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver
Jorge A. Bezerra, Thomas H. Bugge, Hector Melin-Aldana, Gregg Sabla, Keith W. Kombrinck, David P. Witte, and Jay L. Degen
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15143–15148.
PMCID: PMC24787
Retina-specific nuclear receptor: A potential regulator of cellular retinaldehyde-binding protein expressed in retinal pigment epithelium and Müller glial cells
Fang Chen, David J. Figueroa, Alan D. Marmorstein, Qing Zhang, Konstantin Petrukhin, C. Thomas Caskey, and Christopher P. Austin
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15149–15154.
PMCID: PMC24788
Toward an understanding of the biochemical and pharmacological complexity of the saliva of a hematophagous sand fly Lutzomyia longipalpis
Rosane Charlab, Jesus G. Valenzuela, Edgar D. Rowton, and José M. C. Ribeiro
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15155–15160.
PMCID: PMC24789
Estradiol repression of tumor necrosis factor-α transcription requires estrogen receptor activation function-2 and is enhanced by coactivators
Jinping An, Ralff C. J. Ribeiro, Paul Webb, Jan-Åke Gustafsson, Peter J. Kushner, John D. Baxter, and Dale C. Leitman
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15161–15166.
PMCID: PMC24790
Antigen-driven CD4+ T cell and HIV-1 dynamics: Residual viral replication under highly active antiretroviral therapy
Neil M. Ferguson, Frank deWolf, Azra C. Ghani, Christophe Fraser, Christl A. Donnelly, Peter Reiss, Joep M. A. Lange, Sven A. Danner, Geoff P. Garnett, Jaap Goudsmit, and Roy M. Anderson
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15167–15172.
PMCID: PMC24791
Genetic epidemiology of single-nucleotide polymorphisms
A. Collins, C. Lonjou, and N. E. Morton
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15173–15177.
PMCID: PMC24792
Microbiology
Effect of cellular filamentation on adventurous and social gliding motility of Myxococcus xanthus
Hong Sun, Zhaomin Yang, and Wenyuan Shi
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15178–15183.
PMCID: PMC24793
Carbonic anhydrase is an ancient enzyme widespread in prokaryotes
Kerry S. Smith, Claudia Jakubzick, Thomas S. Whittam, and James G. Ferry
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15184–15189.
PMCID: PMC24794
Mycobacterial infection of macrophages results in membrane-permeable phagosomes
R. Teitelbaum, M. Cammer, M. L. Maitland, N. E. Freitag, J. Condeelis, and B. R. Bloom
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15190–15195.
PMCID: PMC24795
Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli
Vanessa Sperandio, Jay L. Mellies, William Nguyen, Sooan Shin, and James B. Kaper
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15196–15201.
PMCID: PMC24796
Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa
Creg Darby, Christine L. Cosma, James H. Thomas, and Colin Manoil
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15202–15207.
PMCID: PMC24797
Neurobiology
Optical images of visible and invisible percepts in the primary visual cortex of primates
Stephen L. Macknik and Michael M. Haglund
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15208–15210.
PMCID: PMC24798
Rapid down-regulation of mammalian Period genes during behavioral resetting of the circadian clock
E. S. Maywood, N. Mrosovsky, M. D. Field, and M. H. Hastings
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15211–15216.
PMCID: PMC24799
Neuronal calcium sparks and intracellular calcium “noise”
Naomi Melamed-Book, Sylvia G. Kachalsky, Igor Kaiserman, and Rami Rahamimoff
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15217–15221.
PMCID: PMC24800
Thalamocortical dysrhythmia: A neurological and neuropsychiatric syndrome characterized by magnetoencephalography
Rodolfo R. Llinás, Urs Ribary, Daniel Jeanmonod, Eugene Kronberg, and Partha P. Mitra
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15222–15227.
PMCID: PMC24801
Calcium channel activation and self-biting in mice
H. A. Jinnah, S. Yitta, T. Drew, B. S. Kim, J. E. Visser, and J. D. Rothstein
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15228–15232.
PMCID: PMC24802
Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease
Kelly R. Bales, Tatyana Verina, David J. Cummins, Yansheng Du, Richard C. Dodel, Josep Saura, Cindy E. Fishman, Cynthia A. DeLong, Pedro Piccardo, Valerie Petegnief, Bernardino Ghetti, and Steven M. Paul
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15233–15238.
PMCID: PMC24803
Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities
W. Ernest Lyons, Laura A. Mamounas, George A. Ricaurte, Vincenzo Coppola, Susan W. Reid, Susan H. Bora, Cornelia Wihler, Vassilis E. Koliatsos, and Lino Tessarollo
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15239–15244.
PMCID: PMC24804
Ablation of P/Q-type Ca2+ channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the α1A-subunit
Kisun Jun, Erika S. Piedras-Rentería, Stephen M. Smith, David B. Wheeler, Seong Beom Lee, Taehoon G. Lee, Hemin Chin, Michael E. Adams, Richard H. Scheller, Richard W. Tsien, and Hee-Sup Shin
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15245–15250.
PMCID: PMC24805
A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo
Alasdair MacKenzie and John Quinn
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15251–15255.
PMCID: PMC24806
Neurotransplantation of magnetically labeled oligodendrocyte progenitors: Magnetic resonance tracking of cell migration and myelination
J. W. M. Bulte, S.-C. Zhang, P. van Gelderen, V. Herynek, E. K. Jordan, I. D. Duncan, and J. A. Frank
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15256–15261.
PMCID: PMC24807
Protein kinase C potentiation of N-methyl-d-aspartate receptor activity is not mediated by phosphorylation of N-methyl-d-aspartate receptor subunits
Xin Zheng, Ling Zhang, Alice P. Wang, Michael V. L. Bennett, and R. Suzanne Zukin
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15262–15267.
PMCID: PMC24808
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)
Kelly M. Crowder, Jane M. Gunther, Theresa A. Jones, Brian D. Hale, Hai Zhuan Zhang, Michael R. Peterson, Richard H. Scheller, Charles Chavkin, and Sandra M. Bajjalieh
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15268–15273.
PMCID: PMC24809
Physiology
Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish
Cunming Duan, Jun Ding, Qin Li, Wellington Tsai, and Kasiani Pozios
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15274–15279.
PMCID: PMC24810
Regulation of cyclooxygenase-2 (COX-2) in rat renal cortex by adrenal glucocorticoids and mineralocorticoids
Ming-Zhi Zhang, Raymond C. Harris, and James A. McKanna
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15280–15285.
PMCID: PMC24811
Serial microanalysis of renal transcriptomes
Bérangère Virlon, Lydie Cheval, Jean-Marie Buhler, Emmanuelle Billon, Alain Doucet, and Jean-Marc Elalouf
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15286–15291.
PMCID: PMC24812
Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel by means of phosphatidylinositol 4,5-bisphosphate metabolism
Lai-Hua Xie, Minoru Horie, and Makoto Takano
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15292–15297.
PMCID: PMC24813
pH gating of ROMK (Kir1.1) channels: Control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome
U. Schulte, H. Hahn, M. Konrad, N. Jeck, C. Derst, K. Wild, S. Weidemann, J. P. Ruppersberg, B. Fakler, and J. Ludwig
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15298–15303.
PMCID: PMC24814
From the Cover:
Alternative splicing, muscle calcium sensitivity, and the modulation of dragonfly flight performance
James H. Marden, Gail H. Fitzhugh, Melisande R. Wolf, Kristina D. Arnold, and Barry Rowan
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15304–15309.
PMCID: PMC24815
Plant Biology
Ozone depletion and UVB radiation: Impact on plant DNA damage in southern South America
M. Cecilia Rousseaux, Carlos L. Ballaré, Carla V. Giordano, Ana L. Scopel, Ana M. Zima, Mariela Szwarcberg-Bracchitta, Peter S. Searles, Martyn M. Caldwell, and Susana B. Díaz
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15310–15315.
PMCID: PMC24816
BAS1: A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis
Michael M. Neff, Serena M. Nguyen, Elizabeth J. Malancharuvil, Shozo Fujioka, Takahiro Noguchi, Hideharu Seto, Masayoshi Tsubuki, Toshio Honda, Suguru Takatsuto, Shigeo Yoshida, and Joanne Chory
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15316–15323.
PMCID: PMC24817
RNA editing in Arabidopsis mitochondria effects 441 C to U changes in ORFs
Philippe Giegé and Axel Brennicke
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15324–15329.
PMCID: PMC24818
Molecular characterization of a mutable pigmentation phenotype and isolation of the first active transposable element from Sorghum bicolor
Surinder Chopra, Volker Brendel, Jianbo Zhang, John D. Axtell, and Thomas Peterson
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15330–15335.
PMCID: PMC24819
Psr1, a nuclear localized protein that regulates phosphorus metabolism in Chlamydomonas
Dennis D. Wykoff, Arthur R. Grossman, Donald P. Weeks, Hideaki Usuda, and Kosuke Shimogawara
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15336–15341.
PMCID: PMC24820
The Arabidopsis cullin AtCUL1 is modified by the ubiquitin-related protein RUB1
J. C. del Pozo and M. Estelle
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15342–15347.
PMCID: PMC24821
A bZIP factor, TRAB1, interacts with VP1 and mediates abscisic acid-induced transcription
Tokunori Hobo, Yasuo Kowyama, and Tsukaho Hattori
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15348–15353.
PMCID: PMC24822
The 9-cis-epoxycarotenoid cleavage reaction is the key regulatory step of abscisic acid biosynthesis in water-stressed bean
Xiaoqiong Qin and Jan A. D. Zeevaart
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15354–15361.
PMCID: PMC24823
Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: Finding of a lipase motif and the induction by methyl jasmonate
Tohru Tsuchiya, Hiroyuki Ohta, Katsuya Okawa, Akihiro Iwamatsu, Hiroshi Shimada, Tatsuru Masuda, and Ken-ichiro Takamiya
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15362–15367.
PMCID: PMC24824
Population Biology
Empirical laws of survival and evolution: Their universality and implications
Mark Ya. Azbel'
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15368–15373.
PMCID: PMC24825
Psychology
Perceptual motion standstill in rapidly moving chromatic displays
Zhong-Lin Lu, Luis A. Lesmes, and George Sperling
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15374–15379.
PMCID: PMC24826
Correction
Proc Natl Acad Sci U S A. 1999 December 21; 96(26): 15380.
PMCID: PMC56188
Corrects: V. J. Emery, et al. Stripe phases in high-temperature superconductors. Proc Natl Acad Sci U S A. 1999 August 3; 96(16): 8814–8817.
Other Issues:  previous | next | latest | archive