| | This journal provides immediate access to some articles. From the Academy The age of the  universe David N. Spergel, Michael Bolte, and Wendy Freedman PMCID: PMC34163 Mathematical approaches to comparative linguistics Tandy Warnow PMCID: PMC34482 Physical Sciences Chemistry Nonenzymatic and enzymatic hydrolysis of alkyl halides: A
theoretical study of the S N2 reactions of acetate and
hydroxide ions with alkyl chlorides Andreas H. Maulitz, Felice C. Lightstone, Ya-Jun Zheng, and Thomas C. Bruice PMCID: PMC21202 Engineering Reported emissions of organic gases are not consistent with observations Ronald C. Henry, Clifford H. Spiegelman, John F. Collins, and EunSug Park PMCID: PMC21203 Geology Isotopes, ice ages, and terminal Proterozoic earth history Alan J. Kaufman, Andrew H. Knoll, and Guy M. Narbonne PMCID: PMC21204 Biological Sciences Applied Biological Sciences Peptidyl-transferase inhibitors have antiviral properties by altering programmed −1 ribosomal frameshifting efficiencies: Development of model systems Jonathan D. Dinman, Maria J. Ruiz-Echevarria, Kevin Czaplinski, and Stuart W. Peltz PMCID: PMC21205 The heat shock-induced hyperphosphorylation of τ is estrogen-independent and prevented by androgens: Implications for Alzheimer disease Sozos Ch. Papasozomenos PMCID: PMC21206 Biochemistry Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments Chih-Yen King, Peter Tittmann, Heinz Gross, Roland Gebert, Markus Aebi, and Kurt Wüthrich PMCID: PMC21207 An extended DNA structure through deoxyribose-base stacking induced by RecA protein Taro Nishinaka, Yutaka Ito, Shigeyuki Yokoyama, and Takehiko Shibata PMCID: PMC21208 Covalent modification of the active site threonine of proteasomal β subunits and the Escherichia coli homolog HslV by a new class of inhibitors Matthew Bogyo, John S. McMaster, Maria Gaczynska, Domenico Tortorella, Alfred L. Goldberg, and Hidde Ploegh PMCID: PMC21209 The rational design and construction of a cuboidal iron–sulfur protein Christopher D. Coldren, Homme W. Hellinga, and John P. Caradonna PMCID: PMC21210 Modular organization of the catalytic center of RNA polymerase Arkady Mustaev, Maxim Kozlov, Vadim Markovtsov, Evgeny Zaychikov, Ludmila Denissova, and Alex Goldfarb PMCID: PMC21211 Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2 Machi Furuta, Hideki Yano, An Zhou, Yves Rouillé, Jens J. Holst, Raymond Carroll, Mariella Ravazzola, Lelio Orci, Hiroto Furuta, and Donald F. Steiner PMCID: PMC21212 Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-Å resolution Srinivasan Raghunathan, Cynthia S. Ricard, Timothy M. Lohman, and Gabriel Waksman PMCID: PMC21213 c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth Hyunsuk Shim, Christine Dolde, Brian C. Lewis, Chyi-Sun Wu, Gerard Dang, Richard A. Jungmann, Riccardo Dalla-Favera, and Chi V. Dang PMCID: PMC21214 Bipartite substrate discrimination by human nucleotide excision repair Martin T. Hess, Urs Schwitter, Mario Petretta, Bernd Giese, and Hanspeter Naegeli PMCID: PMC21215 Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein Siu Sylvia Lee, Robert S. Weiss, and Ronald T. Javier PMCID: PMC21216 In vitro and in vivo characterization of novel mRNA motifs that bind special elongation factor SelB Stefanie J. Klug, Alexander Hüttenhofer, Matthias Kromayer, and Michael Famulok PMCID: PMC21217 Pacifastin, a novel 155-kDa heterodimeric proteinase inhibitor containing a unique transferrin chain Zicai Liang, Lars Sottrup-Jensen, Anna Aspán, Martin Hall, and Kenneth Söderhäll PMCID: PMC21218 DNA damage-dependent transcriptional arrest and termination of RNA polymerase II elongation complexes in DNA template containing HIV-1 promoter Zhuying Wang and Tariq M. Rana PMCID: PMC21219 Monomeric isomers of human interleukin 5 show that 1:1 receptor recruitment is sufficient for function Jun Li, Richard Cook, Michael L. Doyle, Preston Hensley, Dean E. McNulty, and Irwin Chaiken PMCID: PMC21220 Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein Craig E. Cameron, Madhumita Ghosh, Stuart F. J. Le Grice, and Stephen J. Benkovic PMCID: PMC21221 The recombination hotspot Chi is recognized by the translocating RecBCD enzyme as the single strand of DNA containing the sequence 5′-GCTGGTGG-3′ Piero R. Bianco and Stephen C. Kowalczykowski PMCID: PMC21222 Alterations of the outer membrane composition in Escherichia coli lacking the histone-like protein HU Eric Painbeni, Martine Caroff, and Josette Rouviere-Yaniv PMCID: PMC21223 Activation of RNA polymerase II by topologically linked DNA-tracking proteins Mohamed Ouhammouch, Michael H. Sayre, James T. Kadonaga, and E. Peter Geiduschek PMCID: PMC21224 The abalone egg vitelline envelope receptor for sperm lysin is a giant multivalent molecule Willie J. Swanson and Victor D. Vacquier PMCID: PMC21225 Similar processes mediate glycopeptide export from the endoplasmic reticulum in mammalian cells and SaccharomycescerevisiaeKarin Römisch and Bassam R. S. Ali PMCID: PMC21226 Biophysics Estimation of mean exocytic vesicle capacitance in mouse adrenal chromaffin cells Tobias Moser and Erwin Neher PMCID: PMC21227 Voltage gating of Escherichia coli porin channels: Role of the constriction loop Prashant S. Phale, Tilman Schirmer, Alexej Prilipov, Kuo-Long Lou, Ariane Hardmeyer, and Jurg P. Rosenbusch PMCID: PMC21228 Cell Biology Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-α transcription factors Congmei Zeng, André J. van Wijnen, Janet L. Stein, Shari Meyers, Wuhua Sun, Lindsay Shopland, Jeanne B. Lawrence, Sheldon Penman, Jane B. Lian, Gary S. Stein, and Scott W. Hiebert PMCID: PMC21229 Vacuolar H +-ATPase in ocular ciliary epithelium Martin B. Wax, Isao Saito, Tatyana Tenkova, Theodore Krupin, Bernard Becker, Nathan Nelson, Dennis Brown, and Stephen L. Gluck PMCID: PMC21230 Developmental regulation and the role of insulin and insulin receptor in metanephrogenesis Zheng Z. Liu, Anil Kumar, Kosuke Ota, Elisabeth I. Wallner, and Yashpal S. Kanwar PMCID: PMC21231 Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines Mette Nielsen, Keld Kaltoft, Mette Nordahl, Carsten Röpke, Carsten Geisler, Tomas Mustelin, Pauline Dobson, Arne Svejgaard, and Niels Ødum PMCID: PMC21232 Developmental Biology Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action Paul W. Finch, Xi He, Michael J. Kelley, Aykut Üren, R. Paul Schaudies, Nicholas C. Popescu, Stuart Rudikoff, Stuart A. Aaronson, Harold E. Varmus, and Jeffrey S. Rubin PMCID: PMC21233 In vivo repopulating hematopoietic stem cells are present in the murine yolk sac at day 9.0 postcoitus Mervin C. Yoder, Kelly Hiatt, and Pinku Mukherjee PMCID: PMC21234 A “knockdown” mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1 Michael A. McDevitt, Ramesh A. Shivdasani, Yuko Fujiwara, Haidi Yang, and Stuart H. Orkin PMCID: PMC21235 Continuous in vitro propagation of the malaria parasite PlasmodiumvivaxClaudia F. Golenda, Jun Li, and Ronald Rosenberg PMCID: PMC21236 Ecology Defensive production of formic acid (80%) by a carabid beetle (Galerita lecontei) Carmen Rossini, Athula B. Attygalle, Andrés González, Scott R. Smedley, Maria Eisner, Jerrold Meinwald, and Thomas Eisner PMCID: PMC21237 Evolution Evolution subverting essentiality: Dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus Miguel A. Martínez, Nuria Verdaguer, Mauricio G. Mateu, and Esteban Domingo PMCID: PMC21238 Ligand binding was acquired during evolution of nuclear receptors Hector Escriva, Rachid Safi, Catherine Hänni, Marie-Claire Langlois, Pierre Saumitou-Laprade, Dominique Stehelin, André Capron, Raymond Pierce, and Vincent Laudet PMCID: PMC21239 DNA sequence evidence for the segmental allotetraploid origin of maize Brandon S. Gaut and John F. Doebley PMCID: PMC21240 Likelihood-mapping: A simple method to visualize phylogenetic content of a sequence alignment Korbinian Strimmer and Arndt von Haeseler PMCID: PMC21241 Exon/intron structure of aldehyde dehydrogenase genes supports
the “ introns-late” theory Andrey Rzhetsky, Francisco José Ayala, Lily C. Hsu, Cheng Chang, and Akira Yoshida PMCID: PMC21242 Genetics Construction and characterization of a reovirus double temperature-sensitive mutant Michael R. Roner, Igor Nepliouev, Barbara Sherry, and Wolfgang K. Joklik PMCID: PMC21243 Selective amplification via biotin- and restriction-mediated enrichment (SABRE), a novel selective amplification procedure for detection of differentially expressed mRNAs Daniel J. Lavery, Luis Lopez-Molina, Fabienne Fleury-Olela, and Ueli Schibler PMCID: PMC21244 Photocarcinogenesis and inhibition of intercellular adhesion molecule 1 expression in cells of DNA-repair-defective individuals Constanze Ahrens, Markus Grewe, Mark Berneburg, Susanne Grether-Beck, Xavier Quilliet, Mauro Mezzina, Alain Sarasin, Alan R. Lehmann, Colin F. Arlett, and Jean Krutmann PMCID: PMC21245 Impaired fertility in mice deficient for the testicular germ-cell protease PC4 Majambu Mbikay, Haidy Tadros, Norito Ishida, Charlie P. Lerner, Eve De Lamirande, Andrew Chen, Mohamed El-Alfy, Yves Clermont, Nabil G. Seidah, Michel Chrétien, Claude Gagnon, and Elizabeth M. Simpson PMCID: PMC21246 Removal of polymerase-produced mutant sequences from PCR products Jane Smith and Paul Modrich PMCID: PMC21247 Gene targeting by linear duplex DNA frequently occurs by assimilation of a single strand that is subject to preferential mismatch correction W.-Y. Leung, A. Malkova, and J. E. Haber PMCID: PMC21248 The distribution of genes in the genomes of Gramineae Abdelali Barakat, Nicolas Carels, and Giorgio Bernardi PMCID: PMC21249 Gene identification and DNA sequence analysis in the GC-poor 20 megabase region of human chromosome 21 Jingwei Yu, Suhong Tong, Yiping Shen, and Fa-Ten Kao PMCID: PMC21250 RecA-like proteins are components of early meiotic nodules in lily Lorinda K. Anderson, Hildo H. Offenberg, W. M. H. C. Verkuijlen, and Christa Heyting PMCID: PMC21251 Immunology A critical role for neutralizing-antibody-producing B cells, CD4 + T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers Oliver Planz, Stephan Ehl, Esther Furrer, Edit Horvath, Marie-Anne Bründler, Hans Hengartner, and Rolf M. Zinkernagel PMCID: PMC21252 The three-dimensional structure of an H-2L d-peptide complex explains the unique interaction of L d with beta-2 microglobulin and peptide Ganesaratnam K. Balendiran, Joyce C. Solheim, Aideen C. M. Young, Ted H. Hansen, Stanley G. Nathenson, and James C. Sacchettini PMCID: PMC21253 Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity Todd D. Armstrong, Virginia K. Clements, Brian K. Martin, Jenny P.-Y. Ting, and Suzanne Ostrand-Rosenberg PMCID: PMC21254 Selective binding of bacterial toxins to major histocompatibility complex class II-expressing cells is controlled by invariant chain and HLA-DM Pascal M. Lavoie, Jacques Thibodeau, Isabelle Cloutier, Robert Busch, and Rafick-P. Sékaly PMCID: PMC21255 Ly-6C regulates endothelial adhesion and homing of CD8 + T cells by activating integrin-dependent adhesion pathways Arno Hänninen, Ilkka Jaakkola, Marko Salmi, Olli Simell, and Sirpa Jalkanen PMCID: PMC21256 The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation Paul J. Lehner, Jaana T. Karttunen, Gavin W. G. Wilkinson, and Peter Cresswell PMCID: PMC21257 The amino terminus of JAK3 is necessary and sufficient for binding to the common γ chain and confers the ability to transmit interleukin 2-mediated signals Min Chen, Alan Cheng, Yi-Qing Chen, Anka Hymel, Eric P. Hanson, Lida Kimmel, Yasuhiro Minami, Tadatsugu Taniguchi, Paul S. Changelian, and John J. O’Shea PMCID: PMC21258 Medical Sciences Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus John G. Flannery, Sergei Zolotukhin, M. Isabel Vaquero, Matthew M. LaVail, Nicholas Muzyczka, and William W. Hauswirth PMCID: PMC21259 Effect of tissue factor deficiency on mouse and tumor development John R. Toomey, Kenneth E. Kratzer, Nina M. Lasky, and George J. Broze, Jr. PMCID: PMC21260 RAB22 and RAB163/mouse BRCA2: Proteins that specifically interact with the RAD51 protein Ryushin Mizuta, Janine M. LaSalle, Hwei-Ling Cheng, Akira Shinohara, Hideyuki Ogawa, Neal Copeland, Nancy A. Jenkins, Marc Lalande, and Frederick W. Alt PMCID: PMC21261 Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma Kristian Helin, Karin Holm, Anita Niebuhr, Hans Eiberg, Niels Tommerup, Susanne Hougaard, Hans Skovgaard Poulsen, Mogens Spang-Thomsen, and Peter Nørgaard PMCID: PMC21262 Role for Bcl-x L as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis Surender Kharbanda, Pramod Pandey, Lesley Schofield, Sara Israels, Richard Roncinske, Kiyotsugu Yoshida, Ajit Bharti, Zhi-Min Yuan, Satya Saxena, Ralph Weichselbaum, Carlo Nalin, and Donald Kufe PMCID: PMC21263 Dwarfism and age-associated spinal degeneration of heterozygote cmd mice defective in aggrecan Hideto Watanabe, Ken Nakata, Koji Kimata, Isao Nakanishi, and Yoshihiko Yamada PMCID: PMC21264 Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1–1.5 Mb and preparation of a PAC-based physical map Nanding Zhao, Archontoula Stoffel, Pauline W. Wang, James D. Eisenbart, Rafael Espinosa, III, Richard A. Larson, and Michelle M. Le Beau PMCID: PMC21265 Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages Yong Xia and Jay L. Zweier PMCID: PMC21266 Cloning and characterization of the R1 and R2 subunits of ribonucleotide reductase from TrypanosomabruceiAnders Hofer, Peter P. Schmidt, Astrid Gräslund, and Lars Thelander PMCID: PMC21267 Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2Leonidas Tsiokas, Emily Kim, Thierry Arnould, Vikas P. Sukhatme, and Gerd Walz PMCID: PMC21268 Virus dynamics and drug therapy Sebastian Bonhoeffer, Robert M. May, George M. Shaw, and Martin A. Nowak PMCID: PMC21269 Microbiology An intestinal mucin is the target substrate for a baculovirus enhancin Ping Wang and Robert R. Granados PMCID: PMC21270 Neurobiology Novel expression mechanism for synaptic potentiation: Alignment of presynaptic release site and postsynaptic receptor Xiaping Xie, Jim-Shih Liaw, Michel Baudry, and Theodore W. Berger PMCID: PMC21271 “Willed action”: A functional MRI study of the human prefrontal cortex during a sensorimotor task Fahmeed Hyder, Elizabeth A. Phelps, Christopher J. Wiggins, Kevin S. Labar, Andrew M. Blamire, and Robert G. Shulman PMCID: PMC21272 Area-specific regulation of γ-aminobutyric acid type A receptor subtypes by thalamic afferents in developing rat neocortex Jacques Paysan, Albrecht Kossel, Jürgen Bolz, and Jean-Marc Fritschy PMCID: PMC21273 Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues Hong Fei, Hirotaka J. Okano, Cai Li, Gwo-Hwa Lee, Connie Zhao, Robert Darnell, and Jeffrey M. Friedman PMCID: PMC21274 Heat transduction in rat sensory neurons by calcium-dependent activation of a cation channel David B. Reichling and Jon D. Levine PMCID: PMC21275 Extracellular calcium sensed by a novel cation channel in hippocampal neurons Z.-G. Xiong, W.-Y. Lu, and J. F. MacDonald PMCID: PMC21276 Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons Douglas J. Creedon, Malú G. Tansey, Robert H. Baloh, Patricia A. Osborne, Patricia A. Lampe, Timothy J. Fahrner, Robert O. Heuckeroth, Jeffrey Milbrandt, and Eugene M. Johnson, Jr. PMCID: PMC21277 Glutamine synthetase protects against neuronal degeneration in injured retinal tissue Rena Gorovits, Nili Avidan, Noa Avisar, Iftach Shaked, and Lily Vardimon PMCID: PMC21278 Membrane-associated molecules regulate the formation of layer-specific cortical circuits Valerie Castellani and Jürgen Bolz PMCID: PMC21279 In vivo activity-dependent plasticity at cortico-striatal connections: Evidence for physiological long-term potentiation S. Charpier and J. M. Deniau PMCID: PMC21280 Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats Ramon Bernabeu, Lia Bevilaqua, Patricia Ardenghi, Elke Bromberg, Paulo Schmitz, Marino Bianchin, Ivan Izquierdo, and Jorge H. Medina PMCID: PMC21281 A 10-amino acid sequence of fibroblast growth factor 2 is sufficient for its mitogenic activity on neural progenitor cells Jasodhara Ray, Andrew Baird, and Fred H. Gage PMCID: PMC21282 Pharmacology 7-Chloro-3-methyl-3,4-dihydro-2 H-1,2,4-benzothiadiazine S, S-dioxide: A partial modulator of AMPA receptor desensitization devoid of neurotoxicity F. Impagnatiello, A. Oberto, P. Longone, E. Costa, and A. Guidotti PMCID: PMC21283 Physiology Molecular characterization of the sodium channel subunits expressed in mammalian cerebellar Purkinje cells Eleazar Vega-Saenz de Miera, Bernardo Rudy, Mutsuyuki Sugimori, and Rodolfo Llinás PMCID: PMC21284 Relationships between enzymatic flux capacities and metabolic flux rates: Nonequilibrium reactions in muscle glycolysis R. K. Suarez, J. F. Staples, J. R. B. Lighton, and T. G. West PMCID: PMC21285 Activation of heteromeric G protein-gated inward rectifier K + channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons Markus U. Ehrengruber, Craig A. Doupnik, Youfeng Xu, Justine Garvey, Mark C. Jasek, Henry A. Lester, and Norman Davidson PMCID: PMC21286 Plant Biology The AP2 domain of APETALA2 defines
a large new family of DNA binding proteins in ArabidopsisJack K. Okamuro, Brian Caster, Raimundo Villarroel, Marc Van Montagu, and K. Diane Jofuku PMCID: PMC21287 Stress proteins on the yeast cell surface determine resistance to osmotin, a plant antifungal protein Dae-Jin Yun, Yuan Zhao, José M. Pardo, Meena L. Narasimhan, Barbara Damsz, Hyeseung Lee, Laura R. Abad, Matilde Paino D’Urzo, Paul M. Hasegawa, and Ray A. Bressan PMCID: PMC21288 A novel subviral agent associated with a geminivirus: The first report of a DNA satellite Ian B. Dry, Leslie R. Krake, Justin E. Rigden, and M. Ali Rezaian PMCID: PMC21289 Expression of a mutant α-zein creates the floury2 phenotype in transgenic maize Craig E. Coleman, Amy M. Clore, Jerry P. Ranch, Regina Higgins, Mauricio A. Lopes, and Brian A. Larkins PMCID: PMC21290 Overexpression of an Arabidopsis thaliana high-affinity phosphate transporter gene in tobacco cultured cells enhances cell growth under phosphate-limited conditions Norihiro Mitsukawa, Satoru Okumura, Yumiko Shirano, Shigeru Sato, Tomohiko Kato, Satoshi Harashima, and Daisuke Shibata PMCID: PMC21291 Purified vesicles of tobacco cell vacuolar and plasma membranes exhibit dramatically different water permeability and water channel activity Christophe Maurel, Frédérique Tacnet, Josette Güclü, Jean Guern, and Pierre Ripoche PMCID: PMC21292 Psychology The hippocampus and memory for orderly stimulus relations Jeffery A. Dusek and Howard Eichenbaum PMCID: PMC21293 Spatial and temporal coherence in perceptual binding Randolph Blake and Yuede Yang PMCID: PMC21294 Correction Proc Natl Acad Sci U S A. 1997 June 24; 94(13): 7120. PMCID: PMC56137 Corrects: P L Zhao, et al. Sample size determination in combinatorial chemistry. Proc Natl Acad Sci U S A. 1995 October 24; 92(22): 10212–10216. |
