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Volume 97(8);  April 11, 2000
Commentaries
Thinking about p24 proteins and how transport vesicles select their cargo
Chris Kaiser
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3783–3785.
PMCID: PMC33973
Mutant ion channel in cochlear hair cells causes deafness
Laurence Trussell
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3786–3788.
PMCID: PMC33974
Identifying expressed genes
Katherine J. Martin and Arthur B. Pardee
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3789–3791.
PMCID: PMC33975
Filling in the GAPs in the ADP-ribosylation factor story
Julie G. Donaldson
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3792–3794.
PMCID: PMC33976
Physical Sciences
Applied Mathematics
A topological invariant to predict the three-dimensional writhe of ideal configurations of knots and links
Corinne Cerf and Andrzej Stasiak
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3795–3798.
PMCID: PMC18095
Characteristic length scale of the intermediate structure in zero-pressure-gradient boundary layer flow
G. I. Barenblatt, A. J. Chorin, and V. M. Prostokishin
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3799–3802.
PMCID: PMC18096
Chemistry
Photo-control of helix content in a short peptide
Janet R. Kumita, Oliver S. Smart, and G. Andrew Woolley
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3803–3808.
PMCID: PMC18097
Carbon nanotube atomic force microscopy tips: Direct growth by chemical vapor deposition and application to high-resolution imaging
Chin Li Cheung, Jason H. Hafner, and Charles M. Lieber
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3809–3813. Published online 2000 March 28.
PMCID: PMC18098
Geophysics
The 1,800-year oceanic tidal cycle: A possible cause of rapid climate change
Charles D. Keeling and Timothy P. Whorf
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3814–3819. Published online 2000 March 21.
PMCID: PMC18099
Biological Sciences
Agricultural Sciences
Bean α-amylase inhibitor 1 in transgenic peas (Pisum sativum) provides complete protection from pea weevil (Bruchus pisorum) under field conditions
Roger L. Morton, Hart E. Schroeder, Kaye S. Bateman, Maarten J. Chrispeels, Eric Armstrong, and Thomas J. V. Higgins
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3820–3825. Published online 2000 April 4.
PMCID: PMC18100
Applied Biological Sciences
α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification
Karin M. Höld, Nilantha S. Sirisoma, Tomoko Ikeda, Toshio Narahashi, and John E. Casida
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3826–3831. Published online 2000 March 21.
PMCID: PMC18101
Biochemistry
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
Isao Kuraoka, Christina Bender, Anthony Romieu, Jean Cadet, Richard D. Wood, and Tomas Lindahl
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3832–3837. Published online 2000 April 4.
PMCID: PMC18102
The human DINB1 gene encodes the DNA polymerase Polθ
Robert E. Johnson, Satya Prakash, and Louise Prakash
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3838–3843.
PMCID: PMC18103
Reevaluation of the accepted allosteric mechanism of phosphofructokinase from Bacillus stearothermophilus
Jennifer L. Kimmel and Gregory D. Reinhart
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3844–3849. Published online 2000 April 4.
PMCID: PMC18104
Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression
Benyi Li and Q. Ping Dou
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3850–3855. Published online 2000 March 21.
PMCID: PMC18105
Crystal structure of the cystine C-S lyase from Synechocystis: Stabilization of cysteine persulfide for FeS cluster biosynthesis
Tim Clausen, Jens T. Kaiser, Clemens Steegborn, Robert Huber, and Dorothea Kessler
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3856–3861.
PMCID: PMC18106
Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides
M. Faria, C. D. Wood, L. Perrouault, J. S. Nelson, A. Winter, M. R. H. White, C. Hélène, and C. Giovannangeli
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3862–3867.
PMCID: PMC18107
Peptide nucleic acids rather than RNA may have been the first genetic molecule
Kevin E. Nelson, Matthew Levy, and Stanley L. Miller
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3868–3871.
PMCID: PMC18108
Enhanced visibility of hydrogen atoms by neutron crystallography on fully deuterated myoglobin
Fong Shu, Venki Ramakrishnan, and Benno P. Schoenborn
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3872–3877. Published online 2000 March 21.
PMCID: PMC18109
Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task
Amelie Karlstrom, Guofu Zhong, Christoph Rader, Nicholas A. Larsen, Andreas Heine, Roberta Fuller, Benjamin List, Fujie Tanaka, Ian A. Wilson, Carlos F. Barbas, III, and Richard A. Lerner
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3878–3883.
PMCID: PMC18110
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model
Jianmin Fang, Yuen Shing, Dmitri Wiederschain, Li Yan, Catherine Butterfield, Geraldine Jackson, Jay Harper, George Tamvakopoulos, and Marsha A. Moses
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3884–3889.
PMCID: PMC18111
Effects of saturation mutagenesis of the phage SP6 promoter on transcription activity, presented by activity logos
Inkyung Shin, Jinsuk Kim, Charles R. Cantor, and Changwon Kang
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3890–3895.
PMCID: PMC18112
Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome
Maria Falkenberg, I. R. Lehman, and Per Elias
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3896–3900.
PMCID: PMC18113
A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of α2
Rebecca L. Smith and Alexander D. Johnson
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3901–3906. Published online 2000 April 4.
PMCID: PMC18114
Crystal structure of native chicken fibrinogen at 5.5-Å resolution
Zhe Yang, Igor Mochalkin, Leela Veerapandian, Marcia Riley, and Russell F. Doolittle
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3907–3912. Published online 2000 March 28.
PMCID: PMC18115
Identification and characterization of a host protein required for efficient template selection in viral RNA replication
Juana Díez, Masayuki Ishikawa, Masanori Kaido, and Paul Ahlquist
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3913–3918. Published online 2000 April 4.
PMCID: PMC18116
Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
Karolien De Bosscher, Wim Vanden Berghe, Linda Vermeulen, Stéphane Plaisance, Elke Boone, and Guy Haegeman
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3919–3924.
PMCID: PMC18117
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor α gene expression
James V. Falvo, Brigitta M. N. Brinkman, Alla V. Tsytsykova, Eunice Y. Tsai, Tso-Pang Yao, Andrew L. Kung, and Anne E. Goldfeld
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3925–3929.
PMCID: PMC18118
Activation of gene expression by small molecule transcription factors
Anna K. Mapp, Aseem Z. Ansari, Mark Ptashne, and Peter B. Dervan
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3930–3935.
PMCID: PMC18119
Recognition of triple-helical DNA structures by transposon Tn7
Jason E. Rao, Paul S. Miller, and Nancy L. Craig
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3936–3941. Published online 2000 March 28.
PMCID: PMC18120
The Escherichia coli signal transducers PII (GlnB) and GlnK form heterotrimers in vivo: Fine tuning the nitrogen signal cascade
Wally C. van Heeswijk, Daying Wen, Paula Clancy, Rene Jaggi, David L. Ollis, Hans V. Westerhoff, and Subhash G. Vasudevan
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3942–3947.
PMCID: PMC18121
Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites
Shunbin Xiong, Subrahmanyam S. Chirala, and Salih J. Wakil
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3948–3953. Published online 2000 April 4.
PMCID: PMC18122
Predicting protein function from structure: Unique structural features of proteases
Eric W. Stawiski, Albion E. Baucom, Scott C. Lohr, and Lydia M. Gregoret
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3954–3958. Published online 2000 April 4.
PMCID: PMC18123
Biophysics
Carbon nanotube atomic force microscopy tips: Direct growth by chemical vapor deposition and application to high-resolution imaging
Chin Li Cheung, Jason H. Hafner, and Charles M. Lieber
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3809–3813. Published online 2000 March 28.
PMCID: PMC18098
Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters
Li-Qun Gu, Mauro Dalla Serra, J. Bryan Vincent, Gyula Vigh, Stephen Cheley, Orit Braha, and Hagan Bayley
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3959–3964.
PMCID: PMC18124
Predicting ligand-binding function in families of bacterial receptors
Jason M. Johnson and George M. Church
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3965–3970. Published online 2000 March 28.
PMCID: PMC18125
The Holliday junction in an inverted repeat DNA sequence: Sequence effects on the structure of four-way junctions
Brandt F. Eichman, Jeffrey M. Vargason, Blaine H. M. Mooers, and P. Shing Ho
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3971–3976.
PMCID: PMC18126
A statistical mechanical method to optimize energy functions for protein folding
Ugo Bastolla, Michele Vendruscolo, and Ernst-Walter Knapp
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3977–3981.
PMCID: PMC18127
On the direct determination of three-dimensional crystallographic phases at low resolution: Crambin at 6 Å
Douglas L. Dorset
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3982–3986. Published online 2000 March 21.
PMCID: PMC18128
Osmotic stress, crowding, preferential hydration, and binding: A comparison of perspectives
V. A. Parsegian, R. P. Rand, and D. C. Rau
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3987–3992.
PMCID: PMC18129
Cell Biology
Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468
Runqing Lu and Ginette Serrero
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3993–3998.
PMCID: PMC18130
MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16
Bin Zheng, Dan Chen, and Marilyn Gist Farquhar
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3999–4004.
PMCID: PMC18131
Cadherin interaction probed by atomic force microscopy
W. Baumgartner, P. Hinterdorfer, W. Ness, A. Raab, D. Vestweber, H. Schindler, and D. Drenckhahn
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4005–4010. Published online 2000 April 4.
PMCID: PMC18132
From the Cover:
The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton
Paul A. Randazzo, Josefa Andrade, Koichi Miura, Megan T. Brown, Ya-Qiu Long, Stacey Stauffer, Peter Roller, and Jonathan A. Cooper
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4011–4016. Published online 2000 March 21.
PMCID: PMC18133
The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton
Anna Rachel Gallagher, Anna Cedzich, Norbert Gretz, Stefan Somlo, and Ralph Witzgall
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4017–4022.
PMCID: PMC18134
Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression
Gabriela da Silva Xavier, Isabelle Leclerc, Ian P. Salt, Bruno Doiron, D. Grahame Hardie, Axel Kahn, and Guy A. Rutter
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4023–4028.
PMCID: PMC18135
clag9: A cytoadherence gene in Plasmodium falciparum essential for binding of parasitized erythrocytes to CD36
Katharine R. Trenholme, Donald L. Gardiner, Deborah C. Holt, Elizabeth A. Thomas, Alan F. Cowman, and David J. Kemp
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4029–4033. Published online 2000 March 28.
PMCID: PMC18136
From the Cover:
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
Sebastian Springer, Eric Chen, Rainer Duden, Martina Marzioch, Adele Rowley, Susan Hamamoto, Sabeeha Merchant, and Randy Schekman
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4034–4039. Published online 2000 March 28.
PMCID: PMC18138
Membrane-associated GAIP is a phosphoprotein and can be phosphorylated by clathrin-coated vesicles
Thierry Fischer, Eric Elenko, Lei Wan, Gary Thomas, and Marilyn Gist Farquhar
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4040–4045.
PMCID: PMC18141
SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage
Yong Mao, Mei Sun, Shyamal D. Desai, and Leroy F. Liu
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4046–4051. Published online 2000 April 4.
PMCID: PMC18143
Developmental Biology
Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I
Zhongjun Zhou, Suneel S. Apte, Raija Soininen, Renhai Cao, George Y. Baaklini, Richard W. Rauser, Jianming Wang, Yihai Cao, and Karl Tryggvason
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4052–4057. Published online 2000 March 28.
PMCID: PMC18145
Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms
Hong Sun and Reshma Taneja
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4058–4063. Published online 2000 March 28.
PMCID: PMC18147
Distinct Hox protein sequences determine specificity in different tissues
Sophie Chauvet, Samir Merabet, David Bilder, Matthew P. Scott, Jacques Pradel, and Yacine Graba
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4064–4069. Published online 2000 March 28.
PMCID: PMC18149
Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases
Jianrong Lu, Timothy A. McKinsey, Rebekka L. Nicol, and Eric N. Olson
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4070–4075. Published online 2000 March 28.
PMCID: PMC18151
Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates
Sarah A. Shoichet, Talat H. Malik, Joel H. Rothman, and Ramesh A. Shivdasani
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4076–4081.
PMCID: PMC18153
Ecology
Latitudinal gradients of species richness in the deep-sea benthos of the North Atlantic
Michael A. Rex, Carol T. Stuart, and Gina Coyne
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4082–4085. Published online 2000 April 4.
PMCID: PMC18155
Evolution
Seed plant phylogeny inferred from all three plant genomes: Monophyly of extant gymnosperms and origin of Gnetales from conifers
Shu-Miaw Chaw, Christopher L. Parkinson, Yuchang Cheng, Thomas M. Vincent, and Jeffrey D. Palmer
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4086–4091.
PMCID: PMC18157
Phylogeny of seed plants based on all three genomic compartments: Extant gymnosperms are monophyletic and Gnetales' closest relatives are conifers
L. Michelle Bowe, Gwénaële Coat, and Claude W. dePamphilis
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4092–4097.
PMCID: PMC18159
Multiplication of antenna genes as a major adaptation to low light in a marine prokaryote
Laurence Garczarek, Wolfgang R. Hess, Julia Holtzendorff, Georg W. M. van der Staay, and Frédéric Partensky
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4098–4101. Published online 2000 March 21.
PMCID: PMC18161
A lower jaw of Pondaungia cotteri from the Late Middle Eocene Pondaung Formation (Myanmar) confirms its anthropoid status
Yaowalak Chaimanee, Tin Thein, Stéphane Ducrocq, Aung Naing Soe, Mouloud Benammi, Than Tun, Thit Lwin, San Wai, and Jean-Jacques Jaeger
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4102–4105.
PMCID: PMC18163
Ecological character displacement in Plethodon: Biomechanical differences found from a geometric morphometric study
Dean C. Adams and F. James Rohlf
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4106–4111.
PMCID: PMC18164
Compositional genomes: Prebiotic information transfer in mutually catalytic noncovalent assemblies
Daniel Segré, Dafna Ben-Eli, and Doron Lancet
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4112–4117.
PMCID: PMC18166
From the Cover:
Riding the ice age El Niño? Pacific biogeography and evolution of Metrosideros subg. Metrosideros (Myrtaceae) inferred from nuclear ribosomal DNA
S. D. Wright, C. G. Yong, J. W. Dawson, D. J. Whittaker, and R. C. Gardner
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4118–4123. Published online 2000 March 21.
PMCID: PMC18169
Are variations in cuticular hydrocarbons of queens and workers a reliable signal of fertility in the ant Harpegnathos saltator?
Jürgen Liebig, Christian Peeters, Neil J. Oldham, Claus Markstädter, and Bert Hölldobler
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4124–4131.
PMCID: PMC18170
Genetics
Genetic mapping of a naturally occurring hereditary renal cancer syndrome in dogs
Thora J. Jónasdóttir, Cathryn S. Mellersh, Lars Moe, Ragna Heggebø, Hans Gamlem, Elaine A. Ostrander, and Frode Lingaas
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4132–4137. Published online 2000 April 4.
PMCID: PMC18172
A causal link between respiration and senescence in Podospora anserina
Eric Dufour, Joceline Boulay, Vincent Rincheval, and Annie Sainsard-Chanet
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4138–4143. Published online 2000 April 4.
PMCID: PMC18174
Rab geranylgeranyl transferase α mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis
John C. Detter, Qing Zhang, Emilie H. Mules, Edward K. Novak, Vishnu S. Mishra, Wei Li, Elzbieta B. McMurtrie, Velizar T. Tchernev, Margaret R. Wallace, Miguel C. Seabra, Richard T. Swank, and Stephen F. Kingsmore
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4144–4149. Published online 2000 March 28.
PMCID: PMC18176
Comparative organization of cattle chromosome 5 revealed by comparative mapping by annotation and sequence similarity and radiation hybrid mapping
Akihito Ozawa, Mark R. Band, Joshua H. Larson, Jena Donovan, Cheryl A. Green, James E. Womack, and Harris A. Lewin
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4150–4155. Published online 2000 March 28.
PMCID: PMC34555
Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice
Osamu Minowa, Tsuyoshi Arai, Masanori Hirano, Yoshiaki Monden, Shigeyasu Nakai, Mayuko Fukuda, Masaki Itoh, Hiroshi Takano, Yoshitaka Hippou, Hiroyuki Aburatani, Ken-ichi Masumura, Takehiko Nohmi, Susumu Nishimura, and Tetsuo Noda
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4156–4161. Published online 2000 March 21.
PMCID: PMC18180
From the Cover:
Screening poly(dA/dT) cDNAs for gene identification
San Ming Wang, Scott C. Fears, Lin Zhang, Jian-Jun Chen, and Janet D. Rowley
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4162–4167.
PMCID: PMC18183
Genome organization in dicots: Genome duplication in Arabidopsis and synteny between soybean and Arabidopsis
David Grant, Perry Cregan, and Randy C. Shoemaker
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4168–4173. Published online 2000 April 4.
PMCID: PMC18185
High metastatic potential in mice inheriting a targeted p53 missense mutation
Geng Liu, Timothy J. McDonnell, Roberto Montes de Oca Luna, Mini Kapoor, Betsy Mims, Adel K. El-Naggar, and Guillermina Lozano
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4174–4179.
PMCID: PMC18187
Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death
Nobuko Hagiwara, Scott E. Klewer, Ricardo A. Samson, Drew T. Erickson, Mary F. Lyon, and Murray H. Brilliant
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4180–4185.
PMCID: PMC18189
The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light
Peter E. M. Gibbs, Xi-De Wang, Ziqiang Li, Terrence P. McManus, W. Glenn McGregor, Christopher W. Lawrence, and Veronica M. Maher
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4186–4191.
PMCID: PMC18191
Immunology
Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys
Dan H. Barouch, Abie Craiu, Marcelo J. Kuroda, Jörn E. Schmitz, Xin Xiao Zheng, Sampa Santra, Julie D. Frost, Georgia R. Krivulka, Michelle A. Lifton, Carroll L. Crabbs, Gwendolyn Heidecker, Helen C. Perry, Mary-Ellen Davies, Hong Xie, Christine E. Nickerson, Tavis D. Steenbeke, Carol I. Lord, David C. Montefiori, Terry B. Strom, John W. Shiver, Mark G. Lewis, and Norman L. Letvin
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4192–4197. Published online 2000 April 4.
PMCID: PMC18194
Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer
Ali O. Güre, Elisabeth Stockert, Matthew J. Scanlan, Roger S. Keresztes, Dirk Jäger, Nasser K. Altorki, Lloyd J. Old, and Yao-Tseng Chen
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4198–4203.
PMCID: PMC18195
Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice
Alexandra O. Sousa, Richard J. Mazzaccaro, Robert G. Russell, Francis K. Lee, Oliver C. Turner, Seokmann Hong, Luc Van Kaer, and Barry R. Bloom
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4204–4208.
PMCID: PMC18197
Retroviral membrane display of apoptotic effector molecules
David Strehlow, Satoshi Jodo, and Shyr-Te Ju
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4209–4214. Published online 2000 March 28.
PMCID: PMC18199
Identification of a human recent thymic emigrant phenotype
Richard D. McFarland, Daniel C. Douek, Richard A. Koup, and Louis J. Picker
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4215–4220. Published online 2000 March 28.
PMCID: PMC18202
Medical Sciences
Conversion of α-lactalbumin to a protein inducing apoptosis
M. Svensson, A. Håkansson, A.-K. Mossberg, S. Linse, and C. Svanborg
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4221–4226.
PMCID: PMC18203
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
Jennifer Rubin Grandis, Stephanie D. Drenning, Qing Zeng, Simon C. Watkins, Mona F. Melhem, Sohei Endo, Daniel E. Johnson, Leaf Huang, Yukai He, and Jae D. Kim
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4227–4232.
PMCID: PMC18206
Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2
Xinyi Wu, Karin Hepner, Shobha Castelino-Prabhu, Duc Do, Marc B. Kaye, Xiu-Juan Yuan, Jonathan Wood, Christopher Ross, Charles L. Sawyers, and Young E. Whang
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4233–4238.
PMCID: PMC18208
Cardiac fibrosis in mice lacking brain natriuretic peptide
Naohisa Tamura, Yoshihiro Ogawa, Hideki Chusho, Kenji Nakamura, Kazuki Nakao, Michio Suda, Masato Kasahara, Ryuju Hashimoto, Goro Katsuura, Masashi Mukoyama, Hiroshi Itoh, Yoshihiko Saito, Issei Tanaka, Hiroki Otani, Motoya Katsuki, and Kazuwa Nakao
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4239–4244. Published online 2000 March 28.
PMCID: PMC18212
High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
John McNeish, Robert J. Aiello, Deborah Guyot, Tom Turi, Christopher Gabel, Charles Aldinger, Kenneth L. Hoppe, Marsha L. Roach, Lori J. Royer, Jeffery de Wet, Cyril Broccardo, Giovanna Chimini, and Omar L. Francone
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4245–4250.
PMCID: PMC18215
Selective in vivo suppression of T lymphocyte responses in experimental measles virus infection
Stefan Niewiesk, Michaela Götzelmann, and Volker ter Meulen
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4251–4255. Published online 2000 April 4.
PMCID: PMC18218
Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias
Stefania Scala, Giuseppe Portella, Monica Fedele, Gennaro Chiappetta, and Alfredo Fusco
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4256–4261. Published online 2000 April 4.
PMCID: PMC18219
β-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
Shiaw-Yih Lin, Weiya Xia, Jo C. Wang, Ka Yin Kwong, Bill Spohn, Yong Wen, Richard G. Pestell, and Mien-Chie Hung
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4262–4266. Published online 2000 April 4.
PMCID: PMC18221
IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment
Fei-Hua Qiu, Koichiro Wada, Gregory L. Stahl, and Charles N. Serhan
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4267–4272.
PMCID: PMC18224
Destabilization of osteogenesis imperfecta collagen-like model peptides correlates with the identity of the residue replacing glycine
Konrad Beck, Virginia C. Chan, Nigel Shenoy, Alan Kirkpatrick, John A. M. Ramshaw, and Barbara Brodsky
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4273–4278. Published online 2000 March 21.
PMCID: PMC18226
Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: Contribution of the DHEAge Study to a sociobiomedical issue
Etienne-Emile Baulieu, Guy Thomas, Sylvie Legrain, Najiba Lahlou, Marc Roger, Brigitte Debuire, Veronique Faucounau, Laurence Girard, Marie-Pierre Hervy, Florence Latour, Marie-Céline Leaud, Amina Mokrane, Hélène Pitti-Ferrandi, Christophe Trivalle, Olivier de Lacharrière, Stephanie Nouveau, Brigitte Rakoto-Arison, Jean-Claude Souberbielle, Jocelyne Raison, Yves Le Bouc, Agathe Raynaud, Xavier Girerd, and Françoise Forette
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4279–4284.
PMCID: PMC18228
The immunosuppressive macrolide RAD inhibits growth of human Epstein–Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders
Miroslaw Majewski, Magdalena Korecka, Plamen Kossev, Shiyong Li, June Goldman, Jonni Moore, Leslie E. Silberstein, Peter C. Nowell, Walter Schuler, Leslie M. Shaw, and Mariusz A. Wasik
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4285–4290. Published online 2000 April 4.
PMCID: PMC18230
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases
Bey-Dih Chang, Keiko Watanabe, Eugenia V. Broude, Jing Fang, Jason C. Poole, Tatiana V. Kalinichenko, and Igor B. Roninson
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4291–4296.
PMCID: PMC18232
Microbiology
Genetic evidence that the bacteriophage [var phi]X174 lysis protein inhibits cell wall synthesis
Thomas G. Bernhardt, William D. Roof, and Ry Young
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4297–4302.
PMCID: PMC18234
Heteroduplex mobility assay-guided sequence discovery: Elucidation of the small subunit (18S) rDNA sequences of Pfiesteria piscicida and related dinoflagellates from complex algal culture and environmental sample DNA pools
David W. Oldach, Charles F. Delwiche, Kjetill S. Jakobsen, Torstein Tengs, Ernest G. Brown, Jason W. Kempton, Eric F. Schaefer, Holly A. Bowers, Howard B. Glasgow, Jr., JoAnn M. Burkholder, Karen A. Steidinger, and Parke A. Rublee
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4303–4308.
PMCID: PMC18236
Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach
Julie Talon, Mirella Salvatore, Robert E. O'Neill, Yurie Nakaya, Hongyong Zheng, Thomas Muster, Adolfo García-Sastre, and Peter Palese
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4309–4314. Published online 2000 March 21.
PMCID: PMC18238
Neurobiology
Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus
D. Muller, Z. Djebbara-Hannas, P. Jourdain, L. Vutskits, P. Durbec, G. Rougon, and J. Z. Kiss
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4315–4320. Published online 2000 March 21.
PMCID: PMC18239
Control of cocaine-seeking behavior by drug-associated stimuli in rats: Effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens
Friedbert Weiss, Carmen S. Maldonado-Vlaar, Loren H. Parsons, Tony M. Kerr, Diana L. Smith, and Osnat Ben-Shahar
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4321–4326.
PMCID: PMC18240
The synaptic glycoprotein neuroplastin is involved in long-term potentiation at hippocampal CA1 synapses
K. -H. Smalla, H. Matthies, K. Langnäse, S. Shabir, T. M. Böckers, U. Wyneken, S. Staak, M. Krug, P. W. Beesley, and E. D. Gundelfinger
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4327–4332. Published online 2000 April 4.
PMCID: PMC18241
From the Cover:
KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway
Tatjana Kharkovets, Jean-Pierre Hardelin, Saaid Safieddine, Michaela Schweizer, Aziz El-Amraoui, Christine Petit, and Thomas J. Jentsch
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4333–4338.
PMCID: PMC18242
Asynchronous oscillations of two zebrafish CLOCK partners reveal differential clock control and function
Nicolas Cermakian, David Whitmore, Nicholas S. Foulkes, and Paolo Sassone-Corsi
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4339–4344.
PMCID: PMC18243
Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers
Sumiko Kiryu-Seo, Masahiko Sasaki, Hiroya Yokohama, Saya Nakagomi, Teruhisa Hirayama, Shunsuke Aoki, Keiji Wada, and Hiroshi Kiyama
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4345–4350. Published online 2000 April 4.
PMCID: PMC18244
Impairment of synaptic transmission by transient hypoxia in hippocampal slices: Improved recovery in glutathione peroxidase transgenic mice
Denis Furling, Othman Ghribi, Ahmed Lahsaini, Marc-Edouard Mirault, and Guy Massicotte
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4351–4356. Published online 2000 April 4.
PMCID: PMC18245
Expression of α1D subunit mRNA is correlated with L-type Ca2+ channel activity in single neurons of hippocampal “zipper” slices
K. C. Chen, E. M. Blalock, O. Thibault, P. Kaminker, and P. W. Landfield
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4357–4362. Published online 2000 April 4.
PMCID: PMC18246
Pharmacology
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
Juan Llopis, Stefan Westin, Mercedes Ricote, Jiahong Wang, Charles Y. Cho, Riki Kurokawa, Tina-Marie Mullen, David W. Rose, Michael G. Rosenfeld, Roger Y. Tsien, and Christopher K. Glass
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4363–4368.
PMCID: PMC18247
A genetic model defines the importance of the atrial natriuretic peptide receptor (guanylyl cyclase-A) in the regulation of kidney function
Susan K. Dubois, Ichiro Kishimoto, Terence O. Lillis, and David L. Garbers
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4369–4373.
PMCID: PMC18248
Physiology
NADPH oxidase is an O2 sensor in airway chemoreceptors: Evidence from K+ current modulation in wild-type and oxidase-deficient mice
Xiao Wen Fu, Dashou Wang, Colin A. Nurse, Mary C. Dinauer, and Ernest Cutz
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4374–4379.
PMCID: PMC18249
Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle
A. González, W. G. Kirsch, N. Shirokova, G. Pizarro, G. Brum, I. N. Pessah, M. D. Stern, H. Cheng, and E. Ríos
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4380–4385. Published online 2000 April 4.
PMCID: PMC18250
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels
Tonghui Ma, Yuanlin Song, Baoxue Yang, Annemarie Gillespie, Elaine J. Carlson, Charles J. Epstein, and A. S. Verkman
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4386–4391. Published online 2000 March 28.
PMCID: PMC18251
Plant Biology
Mutants of Arabidopsis thaliana defective in the acquisition of tolerance to high temperature stress
Suk-Whan Hong and Elizabeth Vierling
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4392–4397.
PMCID: PMC18252
Psychology
Navigation-related structural change in the hippocampi of taxi drivers
Eleanor A. Maguire, David G. Gadian, Ingrid S. Johnsrude, Catriona D. Good, John Ashburner, Richard S. J. Frackowiak, and Christopher D. Frith
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4398–4403. Published online 2000 March 14.
PMCID: PMC18253
Social Sciences
Economic Sciences
Intentionality detection and “mindreading”: Why does game form matter?
Kevin A. McCabe, Vernon L. Smith, and Michael LePore
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4404–4409.
PMCID: PMC18254
Corrections
Correction
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4410. Published online 2000 April 4.
PMCID: PMC55982
Corrects: H. L. Axelrod, et al. Determination of the binding sites of the proton transfer inhibitors Cd2+ and Zn2+ in bacterial reaction centers. Proc Natl Acad Sci U S A. 2000 February 15; 97(4): 1542–1547.
Correction
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4410. Published online 2000 April 4.
PMCID: PMC55983
Corrects: John M. Greally, et al. Conserved characteristics of heterochromatin-forming DNA at the 15q11-q13 imprinting center. Proc Natl Acad Sci U S A. 1999 December 7; 96(25): 14430–14435.
Correction
Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4410.
PMCID: PMC55984
Corrects: John Herrick, et al. Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA. Proc Natl Acad Sci U S A. 2000 January 4; 97(1): 222–227.
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