| | This journal provides immediate access to some articles. Commentaries Thinking about p24 proteins and how transport vesicles select
their cargo Chris Kaiser Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3783–3785. PMCID: PMC33973 Mutant ion channel in cochlear hair cells causes deafness Laurence Trussell Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3786–3788. PMCID: PMC33974 Identifying expressed genes Katherine J. Martin and Arthur B. Pardee Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3789–3791. PMCID: PMC33975 Filling in the GAPs in the ADP-ribosylation factor story Julie G. Donaldson Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3792–3794. PMCID: PMC33976 Physical Sciences Applied Mathematics A topological invariant to predict the three-dimensional writhe of ideal configurations of knots and links Corinne Cerf and Andrzej Stasiak Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3795–3798. PMCID: PMC18095 Characteristic length scale of the intermediate structure in zero-pressure-gradient boundary layer flow G. I. Barenblatt, A. J. Chorin, and V. M. Prostokishin Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3799–3802. PMCID: PMC18096 Chemistry Photo-control of helix content in a short peptide Janet R. Kumita, Oliver S. Smart, and G. Andrew Woolley Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3803–3808. PMCID: PMC18097 Carbon nanotube atomic force microscopy tips: Direct growth by chemical vapor deposition and application to high-resolution imaging Chin Li Cheung, Jason H. Hafner, and Charles M. Lieber Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3809–3813. Published online 2000 March 28. PMCID: PMC18098 Geophysics The 1,800-year oceanic tidal cycle: A possible cause of rapid
climate change Charles D. Keeling and Timothy P. Whorf Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3814–3819. Published online 2000 March 21. PMCID: PMC18099 Biological Sciences Agricultural Sciences Bean α-amylase inhibitor 1 in transgenic peas (Pisum sativum) provides complete protection from pea weevil (Bruchus pisorum) under field conditions Roger L. Morton, Hart E. Schroeder, Kaye S. Bateman, Maarten J. Chrispeels, Eric Armstrong, and Thomas J. V. Higgins Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3820–3825. Published online 2000 April 4. PMCID: PMC18100 Applied Biological Sciences α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification Karin M. Höld, Nilantha S. Sirisoma, Tomoko Ikeda, Toshio Narahashi, and John E. Casida Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3826–3831. Published online 2000 March 21. PMCID: PMC18101 Biochemistry Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells Isao Kuraoka, Christina Bender, Anthony Romieu, Jean Cadet, Richard D. Wood, and Tomas Lindahl Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3832–3837. Published online 2000 April 4. PMCID: PMC18102 The human DINB1 gene encodes the DNA polymerase Polθ Robert E. Johnson, Satya Prakash, and Louise Prakash Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3838–3843. PMCID: PMC18103 Reevaluation of the accepted allosteric mechanism of phosphofructokinase from Bacillus stearothermophilus Jennifer L. Kimmel and Gregory D. Reinhart Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3844–3849. Published online 2000 April 4. PMCID: PMC18104 Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression Benyi Li and Q. Ping Dou Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3850–3855. Published online 2000 March 21. PMCID: PMC18105 Crystal structure of the cystine C-S lyase from Synechocystis: Stabilization of cysteine persulfide for FeS cluster biosynthesis Tim Clausen, Jens T. Kaiser, Clemens Steegborn, Robert Huber, and Dorothea Kessler Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3856–3861. PMCID: PMC18106 Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides M. Faria, C. D. Wood, L. Perrouault, J. S. Nelson, A. Winter, M. R. H. White, C. Hélène, and C. Giovannangeli Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3862–3867. PMCID: PMC18107 Peptide nucleic acids rather than RNA may have been the first genetic molecule Kevin E. Nelson, Matthew Levy, and Stanley L. Miller Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3868–3871. PMCID: PMC18108 Enhanced visibility of hydrogen atoms by neutron crystallography on fully deuterated myoglobin Fong Shu, Venki Ramakrishnan, and Benno P. Schoenborn Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3872–3877. Published online 2000 March 21. PMCID: PMC18109 Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task Amelie Karlstrom, Guofu Zhong, Christoph Rader, Nicholas A. Larsen, Andreas Heine, Roberta Fuller, Benjamin List, Fujie Tanaka, Ian A. Wilson, Carlos F. Barbas, III, and Richard A. Lerner Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3878–3883. PMCID: PMC18110 Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model Jianmin Fang, Yuen Shing, Dmitri Wiederschain, Li Yan, Catherine Butterfield, Geraldine Jackson, Jay Harper, George Tamvakopoulos, and Marsha A. Moses Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3884–3889. PMCID: PMC18111 Effects of saturation mutagenesis of the phage SP6 promoter on transcription activity, presented by activity logos Inkyung Shin, Jinsuk Kim, Charles R. Cantor, and Changwon Kang Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3890–3895. PMCID: PMC18112 Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome Maria Falkenberg, I. R. Lehman, and Per Elias Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3896–3900. PMCID: PMC18113 A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of α2 Rebecca L. Smith and Alexander D. Johnson Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3901–3906. Published online 2000 April 4. PMCID: PMC18114 Crystal structure of native chicken fibrinogen at 5.5-Å resolution Zhe Yang, Igor Mochalkin, Leela Veerapandian, Marcia Riley, and Russell F. Doolittle Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3907–3912. Published online 2000 March 28. PMCID: PMC18115 Identification and characterization of a host protein required for efficient template selection in viral RNA replication Juana Díez, Masayuki Ishikawa, Masanori Kaido, and Paul Ahlquist Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3913–3918. Published online 2000 April 4. PMCID: PMC18116 Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell Karolien De Bosscher, Wim Vanden Berghe, Linda Vermeulen, Stéphane Plaisance, Elke Boone, and Guy Haegeman Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3919–3924. PMCID: PMC18117 A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor α gene expression James V. Falvo, Brigitta M. N. Brinkman, Alla V. Tsytsykova, Eunice Y. Tsai, Tso-Pang Yao, Andrew L. Kung, and Anne E. Goldfeld Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3925–3929. PMCID: PMC18118 Activation of gene expression by small molecule transcription factors Anna K. Mapp, Aseem Z. Ansari, Mark Ptashne, and Peter B. Dervan Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3930–3935. PMCID: PMC18119 Recognition of triple-helical DNA structures by transposon Tn7 Jason E. Rao, Paul S. Miller, and Nancy L. Craig Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3936–3941. Published online 2000 March 28. PMCID: PMC18120 The Escherichia coli signal transducers PII (GlnB) and GlnK form heterotrimers in vivo: Fine tuning the nitrogen signal cascade Wally C. van Heeswijk, Daying Wen, Paula Clancy, Rene Jaggi, David L. Ollis, Hans V. Westerhoff, and Subhash G. Vasudevan Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3942–3947. PMCID: PMC18121 Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites Shunbin Xiong, Subrahmanyam S. Chirala, and Salih J. Wakil Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3948–3953. Published online 2000 April 4. PMCID: PMC18122 Predicting protein function from structure: Unique structural features of proteases Eric W. Stawiski, Albion E. Baucom, Scott C. Lohr, and Lydia M. Gregoret Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3954–3958. Published online 2000 April 4. PMCID: PMC18123 Biophysics Carbon nanotube atomic force microscopy tips: Direct growth by chemical vapor deposition and application to high-resolution imaging Chin Li Cheung, Jason H. Hafner, and Charles M. Lieber Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3809–3813. Published online 2000 March 28. PMCID: PMC18098 Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters Li-Qun Gu, Mauro Dalla Serra, J. Bryan Vincent, Gyula Vigh, Stephen Cheley, Orit Braha, and Hagan Bayley Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3959–3964. PMCID: PMC18124 Predicting ligand-binding function in families of bacterial receptors Jason M. Johnson and George M. Church Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3965–3970. Published online 2000 March 28. PMCID: PMC18125 The Holliday junction in an inverted repeat DNA sequence: Sequence effects on the structure of four-way junctions Brandt F. Eichman, Jeffrey M. Vargason, Blaine H. M. Mooers, and P. Shing Ho Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3971–3976. PMCID: PMC18126 A statistical mechanical method to optimize energy functions for protein folding Ugo Bastolla, Michele Vendruscolo, and Ernst-Walter Knapp Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3977–3981. PMCID: PMC18127 On the direct determination of three-dimensional crystallographic phases at low resolution: Crambin at 6 Å Douglas L. Dorset Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3982–3986. Published online 2000 March 21. PMCID: PMC18128 Osmotic stress, crowding, preferential hydration, and binding: A comparison of perspectives V. A. Parsegian, R. P. Rand, and D. C. Rau Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3987–3992. PMCID: PMC18129 Cell Biology Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468 Runqing Lu and Ginette Serrero Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3993–3998. PMCID: PMC18130 MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16 Bin Zheng, Dan Chen, and Marilyn Gist Farquhar Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 3999–4004. PMCID: PMC18131 Cadherin interaction probed by atomic force microscopy W. Baumgartner, P. Hinterdorfer, W. Ness, A. Raab, D. Vestweber, H. Schindler, and D. Drenckhahn Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4005–4010. Published online 2000 April 4. PMCID: PMC18132 From the Cover: The Arf GTPase-activating protein ASAP1 regulates the actin cytoskeleton Paul A. Randazzo, Josefa Andrade, Koichi Miura, Megan T. Brown, Ya-Qiu Long, Stacey Stauffer, Peter Roller, and Jonathan A. Cooper Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4011–4016. Published online 2000 March 21. PMCID: PMC18133 The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton Anna Rachel Gallagher, Anna Cedzich, Norbert Gretz, Stefan Somlo, and Ralph Witzgall Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4017–4022. PMCID: PMC18134 Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression Gabriela da Silva Xavier, Isabelle Leclerc, Ian P. Salt, Bruno Doiron, D. Grahame Hardie, Axel Kahn, and Guy A. Rutter Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4023–4028. PMCID: PMC18135 clag9: A cytoadherence gene in Plasmodium falciparum essential for binding of parasitized erythrocytes to CD36 Katharine R. Trenholme, Donald L. Gardiner, Deborah C. Holt, Elizabeth A. Thomas, Alan F. Cowman, and David J. Kemp Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4029–4033. Published online 2000 March 28. PMCID: PMC18136 From the Cover: The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae Sebastian Springer, Eric Chen, Rainer Duden, Martina Marzioch, Adele Rowley, Susan Hamamoto, Sabeeha Merchant, and Randy Schekman Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4034–4039. Published online 2000 March 28. PMCID: PMC18138 Membrane-associated GAIP is a phosphoprotein and can be phosphorylated by clathrin-coated vesicles Thierry Fischer, Eric Elenko, Lei Wan, Gary Thomas, and Marilyn Gist Farquhar Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4040–4045. PMCID: PMC18141 SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage Yong Mao, Mei Sun, Shyamal D. Desai, and Leroy F. Liu Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4046–4051. Published online 2000 April 4. PMCID: PMC18143 Developmental Biology Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I Zhongjun Zhou, Suneel S. Apte, Raija Soininen, Renhai Cao, George Y. Baaklini, Richard W. Rauser, Jianming Wang, Yihai Cao, and Karl Tryggvason Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4052–4057. Published online 2000 March 28. PMCID: PMC18145 Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms Hong Sun and Reshma Taneja Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4058–4063. Published online 2000 March 28. PMCID: PMC18147 Distinct Hox protein sequences determine specificity in different tissues Sophie Chauvet, Samir Merabet, David Bilder, Matthew P. Scott, Jacques Pradel, and Yacine Graba Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4064–4069. Published online 2000 March 28. PMCID: PMC18149 Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases Jianrong Lu, Timothy A. McKinsey, Rebekka L. Nicol, and Eric N. Olson Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4070–4075. Published online 2000 March 28. PMCID: PMC18151 Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates Sarah A. Shoichet, Talat H. Malik, Joel H. Rothman, and Ramesh A. Shivdasani Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4076–4081. PMCID: PMC18153 Ecology Latitudinal gradients of species richness in the deep-sea benthos of the North Atlantic Michael A. Rex, Carol T. Stuart, and Gina Coyne Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4082–4085. Published online 2000 April 4. PMCID: PMC18155 Evolution Seed plant phylogeny inferred from all three plant genomes: Monophyly of extant gymnosperms and origin of Gnetales from conifers Shu-Miaw Chaw, Christopher L. Parkinson, Yuchang Cheng, Thomas M. Vincent, and Jeffrey D. Palmer Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4086–4091. PMCID: PMC18157 Phylogeny of seed plants based on all three genomic compartments: Extant gymnosperms are monophyletic and Gnetales' closest relatives are conifers L. Michelle Bowe, Gwénaële Coat, and Claude W. dePamphilis Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4092–4097. PMCID: PMC18159 Multiplication of antenna genes as a major adaptation to low light in a marine prokaryote Laurence Garczarek, Wolfgang R. Hess, Julia Holtzendorff, Georg W. M. van der Staay, and Frédéric Partensky Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4098–4101. Published online 2000 March 21. PMCID: PMC18161 A lower jaw of Pondaungia cotteri from the Late Middle Eocene Pondaung Formation (Myanmar) confirms its anthropoid status Yaowalak Chaimanee, Tin Thein, Stéphane Ducrocq, Aung Naing Soe, Mouloud Benammi, Than Tun, Thit Lwin, San Wai, and Jean-Jacques Jaeger Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4102–4105. PMCID: PMC18163 Ecological character displacement in Plethodon: Biomechanical differences found from a geometric morphometric study Dean C. Adams and F. James Rohlf Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4106–4111. PMCID: PMC18164 Compositional genomes: Prebiotic information transfer in mutually catalytic noncovalent assemblies Daniel Segré, Dafna Ben-Eli, and Doron Lancet Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4112–4117. PMCID: PMC18166 From the Cover: Riding the ice age El Niño? Pacific biogeography and evolution of Metrosideros subg. Metrosideros (Myrtaceae) inferred from nuclear ribosomal DNA S. D. Wright, C. G. Yong, J. W. Dawson, D. J. Whittaker, and R. C. Gardner Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4118–4123. Published online 2000 March 21. PMCID: PMC18169 INAUGURAL ARTICLE by a Recently Elected Academy Member: Are variations in cuticular hydrocarbons of queens and workers a
reliable signal of fertility in the ant
Harpegnathos saltator? Jürgen Liebig, Christian Peeters, Neil J. Oldham, Claus Markstädter, and Bert Hölldobler Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4124–4131. PMCID: PMC18170 Genetics Genetic mapping of a naturally occurring hereditary renal cancer syndrome in dogs Thora J. Jónasdóttir, Cathryn S. Mellersh, Lars Moe, Ragna Heggebø, Hans Gamlem, Elaine A. Ostrander, and Frode Lingaas Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4132–4137. Published online 2000 April 4. PMCID: PMC18172 A causal link between respiration and senescence in Podospora anserina Eric Dufour, Joceline Boulay, Vincent Rincheval, and Annie Sainsard-Chanet Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4138–4143. Published online 2000 April 4. PMCID: PMC18174 Rab geranylgeranyl transferase α mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesis John C. Detter, Qing Zhang, Emilie H. Mules, Edward K. Novak, Vishnu S. Mishra, Wei Li, Elzbieta B. McMurtrie, Velizar T. Tchernev, Margaret R. Wallace, Miguel C. Seabra, Richard T. Swank, and Stephen F. Kingsmore Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4144–4149. Published online 2000 March 28. PMCID: PMC18176 INAUGURAL ARTICLE by a Recently Elected Academy Member: Comparative organization of cattle chromosome 5 revealed by comparative mapping by annotation and sequence similarity and radiation hybrid mapping Akihito Ozawa, Mark R. Band, Joshua H. Larson, Jena Donovan, Cheryl A. Green, James E. Womack, and Harris A. Lewin Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4150–4155. Published online 2000 March 28. PMCID: PMC34555 Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice Osamu Minowa, Tsuyoshi Arai, Masanori Hirano, Yoshiaki Monden, Shigeyasu Nakai, Mayuko Fukuda, Masaki Itoh, Hiroshi Takano, Yoshitaka Hippou, Hiroyuki Aburatani, Ken-ichi Masumura, Takehiko Nohmi, Susumu Nishimura, and Tetsuo Noda Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4156–4161. Published online 2000 March 21. PMCID: PMC18180 From the Cover: Screening poly(dA/dT)− cDNAs for gene identification San Ming Wang, Scott C. Fears, Lin Zhang, Jian-Jun Chen, and Janet D. Rowley Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4162–4167. PMCID: PMC18183 Genome organization in dicots: Genome duplication in Arabidopsis and synteny between soybean and Arabidopsis David Grant, Perry Cregan, and Randy C. Shoemaker Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4168–4173. Published online 2000 April 4. PMCID: PMC18185 High metastatic potential in mice inheriting a targeted p53 missense mutation Geng Liu, Timothy J. McDonnell, Roberto Montes de Oca Luna, Mini Kapoor, Betsy Mims, Adel K. El-Naggar, and Guillermina Lozano Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4174–4179. PMCID: PMC18187 Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death Nobuko Hagiwara, Scott E. Klewer, Ricardo A. Samson, Drew T. Erickson, Mary F. Lyon, and Murray H. Brilliant Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4180–4185. PMCID: PMC18189 The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light Peter E. M. Gibbs, Xi-De Wang, Ziqiang Li, Terrence P. McManus, W. Glenn McGregor, Christopher W. Lawrence, and Veronica M. Maher Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4186–4191. PMCID: PMC18191 Immunology Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys Dan H. Barouch, Abie Craiu, Marcelo J. Kuroda, Jörn E. Schmitz, Xin Xiao Zheng, Sampa Santra, Julie D. Frost, Georgia R. Krivulka, Michelle A. Lifton, Carroll L. Crabbs, Gwendolyn Heidecker, Helen C. Perry, Mary-Ellen Davies, Hong Xie, Christine E. Nickerson, Tavis D. Steenbeke, Carol I. Lord, David C. Montefiori, Terry B. Strom, John W. Shiver, Mark G. Lewis, and Norman L. Letvin Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4192–4197. Published online 2000 April 4. PMCID: PMC18194 Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer Ali O. Güre, Elisabeth Stockert, Matthew J. Scanlan, Roger S. Keresztes, Dirk Jäger, Nasser K. Altorki, Lloyd J. Old, and Yao-Tseng Chen Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4198–4203. PMCID: PMC18195 Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice Alexandra O. Sousa, Richard J. Mazzaccaro, Robert G. Russell, Francis K. Lee, Oliver C. Turner, Seokmann Hong, Luc Van Kaer, and Barry R. Bloom Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4204–4208. PMCID: PMC18197 Retroviral membrane display of apoptotic effector molecules David Strehlow, Satoshi Jodo, and Shyr-Te Ju Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4209–4214. Published online 2000 March 28. PMCID: PMC18199 Identification of a human recent thymic emigrant phenotype Richard D. McFarland, Daniel C. Douek, Richard A. Koup, and Louis J. Picker Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4215–4220. Published online 2000 March 28. PMCID: PMC18202 Medical Sciences Conversion of α-lactalbumin to a protein inducing apoptosis M. Svensson, A. Håkansson, A.-K. Mossberg, S. Linse, and C. Svanborg Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4221–4226. PMCID: PMC18203 Constitutive activation of Stat3 signaling
abrogates apoptosis in squamous cell carcinogenesis
in vivo Jennifer Rubin Grandis, Stephanie D. Drenning, Qing Zeng, Simon C. Watkins, Mona F. Melhem, Sohei Endo, Daniel E. Johnson, Leaf Huang, Yukai He, and Jae D. Kim Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4227–4232. PMCID: PMC18206 Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2 Xinyi Wu, Karin Hepner, Shobha Castelino-Prabhu, Duc Do, Marc B. Kaye, Xiu-Juan Yuan, Jonathan Wood, Christopher Ross, Charles L. Sawyers, and Young E. Whang Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4233–4238. PMCID: PMC18208 Cardiac fibrosis in mice lacking brain natriuretic peptide Naohisa Tamura, Yoshihiro Ogawa, Hideki Chusho, Kenji Nakamura, Kazuki Nakao, Michio Suda, Masato Kasahara, Ryuju Hashimoto, Goro Katsuura, Masashi Mukoyama, Hiroshi Itoh, Yoshihiko Saito, Issei Tanaka, Hiroki Otani, Motoya Katsuki, and Kazuwa Nakao Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4239–4244. Published online 2000 March 28. PMCID: PMC18212 High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1 John McNeish, Robert J. Aiello, Deborah Guyot, Tom Turi, Christopher Gabel, Charles Aldinger, Kenneth L. Hoppe, Marsha L. Roach, Lori J. Royer, Jeffery de Wet, Cyril Broccardo, Giovanna Chimini, and Omar L. Francone Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4245–4250. PMCID: PMC18215 Selective in vivo suppression of T lymphocyte responses in experimental measles virus infection Stefan Niewiesk, Michaela Götzelmann, and Volker ter Meulen Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4251–4255. Published online 2000 April 4. PMCID: PMC18218 Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias Stefania Scala, Giuseppe Portella, Monica Fedele, Gennaro Chiappetta, and Alfredo Fusco Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4256–4261. Published online 2000 April 4. PMCID: PMC18219 β-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression Shiaw-Yih Lin, Weiya Xia, Jo C. Wang, Ka Yin Kwong, Bill Spohn, Yong Wen, Richard G. Pestell, and Mien-Chie Hung Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4262–4266. Published online 2000 April 4. PMCID: PMC18221 IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment Fei-Hua Qiu, Koichiro Wada, Gregory L. Stahl, and Charles N. Serhan Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4267–4272. PMCID: PMC18224 Destabilization of osteogenesis imperfecta collagen-like model peptides correlates with the identity of the residue replacing glycine Konrad Beck, Virginia C. Chan, Nigel Shenoy, Alan Kirkpatrick, John A. M. Ramshaw, and Barbara Brodsky Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4273–4278. Published online 2000 March 21. PMCID: PMC18226 Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: Contribution of the DHEAge Study to a sociobiomedical issue Etienne-Emile Baulieu, Guy Thomas, Sylvie Legrain, Najiba Lahlou, Marc Roger, Brigitte Debuire, Veronique Faucounau, Laurence Girard, Marie-Pierre Hervy, Florence Latour, Marie-Céline Leaud, Amina Mokrane, Hélène Pitti-Ferrandi, Christophe Trivalle, Olivier de Lacharrière, Stephanie Nouveau, Brigitte Rakoto-Arison, Jean-Claude Souberbielle, Jocelyne Raison, Yves Le Bouc, Agathe Raynaud, Xavier Girerd, and Françoise Forette Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4279–4284. PMCID: PMC18228 The immunosuppressive macrolide RAD inhibits growth of human Epstein–Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders Miroslaw Majewski, Magdalena Korecka, Plamen Kossev, Shiyong Li, June Goldman, Jonni Moore, Leslie E. Silberstein, Peter C. Nowell, Walter Schuler, Leslie M. Shaw, and Mariusz A. Wasik Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4285–4290. Published online 2000 April 4. PMCID: PMC18230 Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases Bey-Dih Chang, Keiko Watanabe, Eugenia V. Broude, Jing Fang, Jason C. Poole, Tatiana V. Kalinichenko, and Igor B. Roninson Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4291–4296. PMCID: PMC18232 Microbiology Genetic evidence that the bacteriophage ![[var phi]](corehtml/pmc/pmcents/x03C6.gif) X174 lysis protein inhibits cell wall synthesis Thomas G. Bernhardt, William D. Roof, and Ry Young Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4297–4302. PMCID: PMC18234 Heteroduplex mobility assay-guided sequence discovery: Elucidation of the small subunit (18S) rDNA sequences of Pfiesteria piscicida and related dinoflagellates from complex algal culture and environmental sample DNA pools David W. Oldach, Charles F. Delwiche, Kjetill S. Jakobsen, Torstein Tengs, Ernest G. Brown, Jason W. Kempton, Eric F. Schaefer, Holly A. Bowers, Howard B. Glasgow, Jr., JoAnn M. Burkholder, Karen A. Steidinger, and Parke A. Rublee Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4303–4308. PMCID: PMC18236 Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach Julie Talon, Mirella Salvatore, Robert E. O'Neill, Yurie Nakaya, Hongyong Zheng, Thomas Muster, Adolfo García-Sastre, and Peter Palese Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4309–4314. Published online 2000 March 21. PMCID: PMC18238 Neurobiology Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus D. Muller, Z. Djebbara-Hannas, P. Jourdain, L. Vutskits, P. Durbec, G. Rougon, and J. Z. Kiss Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4315–4320. Published online 2000 March 21. PMCID: PMC18239 Control of cocaine-seeking behavior by drug-associated stimuli in rats: Effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens Friedbert Weiss, Carmen S. Maldonado-Vlaar, Loren H. Parsons, Tony M. Kerr, Diana L. Smith, and Osnat Ben-Shahar Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4321–4326. PMCID: PMC18240 The synaptic glycoprotein neuroplastin is involved in long-term potentiation at hippocampal CA1 synapses K. -H. Smalla, H. Matthies, K. Langnäse, S. Shabir, T. M. Böckers, U. Wyneken, S. Staak, M. Krug, P. W. Beesley, and E. D. Gundelfinger Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4327–4332. Published online 2000 April 4. PMCID: PMC18241 From the Cover: KCNQ4, a K+ channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway Tatjana Kharkovets, Jean-Pierre Hardelin, Saaid Safieddine, Michaela Schweizer, Aziz El-Amraoui, Christine Petit, and Thomas J. Jentsch Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4333–4338. PMCID: PMC18242 Asynchronous oscillations of two zebrafish CLOCK partners reveal differential clock control and function Nicolas Cermakian, David Whitmore, Nicholas S. Foulkes, and Paolo Sassone-Corsi Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4339–4344. PMCID: PMC18243 Damage-induced neuronal endopeptidase (DINE) is a unique metallopeptidase expressed in response to neuronal damage and activates superoxide scavengers Sumiko Kiryu-Seo, Masahiko Sasaki, Hiroya Yokohama, Saya Nakagomi, Teruhisa Hirayama, Shunsuke Aoki, Keiji Wada, and Hiroshi Kiyama Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4345–4350. Published online 2000 April 4. PMCID: PMC18244 Impairment of synaptic transmission by transient hypoxia in hippocampal slices: Improved recovery in glutathione peroxidase transgenic mice Denis Furling, Othman Ghribi, Ahmed Lahsaini, Marc-Edouard Mirault, and Guy Massicotte Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4351–4356. Published online 2000 April 4. PMCID: PMC18245 Expression of α1D subunit mRNA is correlated with L-type Ca2+ channel activity in single neurons of hippocampal “zipper” slices K. C. Chen, E. M. Blalock, O. Thibault, P. Kaminker, and P. W. Landfield Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4357–4362. Published online 2000 April 4. PMCID: PMC18246 Pharmacology Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription Juan Llopis, Stefan Westin, Mercedes Ricote, Jiahong Wang, Charles Y. Cho, Riki Kurokawa, Tina-Marie Mullen, David W. Rose, Michael G. Rosenfeld, Roger Y. Tsien, and Christopher K. Glass Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4363–4368. PMCID: PMC18247 A genetic model defines the importance of the atrial natriuretic peptide receptor (guanylyl cyclase-A) in the regulation of kidney function Susan K. Dubois, Ichiro Kishimoto, Terence O. Lillis, and David L. Garbers Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4369–4373. PMCID: PMC18248 Physiology NADPH oxidase is an O2 sensor in airway chemoreceptors: Evidence from K+ current modulation in wild-type and oxidase-deficient mice Xiao Wen Fu, Dashou Wang, Colin A. Nurse, Mary C. Dinauer, and Ernest Cutz Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4374–4379. PMCID: PMC18249 Involvement of multiple intracellular release channels in calcium sparks of skeletal muscle A. González, W. G. Kirsch, N. Shirokova, G. Pizarro, G. Brum, I. N. Pessah, M. D. Stern, H. Cheng, and E. Ríos Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4380–4385. Published online 2000 April 4. PMCID: PMC18250 Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels Tonghui Ma, Yuanlin Song, Baoxue Yang, Annemarie Gillespie, Elaine J. Carlson, Charles J. Epstein, and A. S. Verkman Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4386–4391. Published online 2000 March 28. PMCID: PMC18251 Plant Biology Mutants of Arabidopsis thaliana defective in the acquisition of tolerance to high temperature stress Suk-Whan Hong and Elizabeth Vierling Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4392–4397. PMCID: PMC18252 Psychology Navigation-related structural change in the hippocampi of taxi drivers Eleanor A. Maguire, David G. Gadian, Ingrid S. Johnsrude, Catriona D. Good, John Ashburner, Richard S. J. Frackowiak, and Christopher D. Frith Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4398–4403. Published online 2000 March 14. PMCID: PMC18253 Social Sciences Economic Sciences Intentionality detection and “mindreading”: Why does
game form matter? Kevin A. McCabe, Vernon L. Smith, and Michael LePore Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4404–4409. PMCID: PMC18254 Corrections Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4410. Published online 2000 April 4. PMCID: PMC55982 Corrects: H. L. Axelrod, et al. Determination of the binding sites of the proton transfer
inhibitors Cd2+ and Zn2+ in bacterial
reaction centers. Proc Natl Acad Sci U S A. 2000 February 15; 97(4): 1542–1547. Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4410. Published online 2000 April 4. PMCID: PMC55983 Corrects: John M. Greally, et al. Conserved characteristics of heterochromatin-forming DNA at the
15q11-q13 imprinting center. Proc Natl Acad Sci U S A. 1999 December 7; 96(25): 14430–14435. Proc Natl Acad Sci U S A. 2000 April 11; 97(8): 4410. PMCID: PMC55984 Corrects: John Herrick, et al. Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA. Proc Natl Acad Sci U S A. 2000 January 4; 97(1): 222–227. |