| | This journal provides immediate access to some articles. Commentaries Interplay of intrinsic and extrinsic signals in yeast
differentiation Hiten D. Madhani Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13461–13463. Published online 2000 November 28. PMCID: PMC34079 The dystrophin-associated glycoprotein complex: What parts can
you do without? H. Lee Sweeney and Elisabeth R. Barton Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13464–13466. Published online 2000 November 28. PMCID: PMC34080 Pushing the limits of cellular microbiology: Microarrays to study
bacteria–host cell intimate contacts Rino Rappuoli Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13467–13469. Published online 2000 November 28. PMCID: PMC34081 A barrier runs through it … or maybe just a river Robert K. Colwell Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13470–13472. Published online 2000 November 28. PMCID: PMC34082 Epidermal stem cells: Properties, markers, and location Robert M. Lavker and Tung-Tien Sun Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13473–13475. Published online 2000 November 21. PMCID: PMC34083 Language-related cortex in deaf individuals: Functional
specialization for language or perceptual plasticity? David Caplan Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13476–13477. PMCID: PMC34084 Physical Sciences Applied Physical Sciences Chaotic flow: The physics of species coexistence György Károlyi, Áron Péntek, István Scheuring, Tamás Tél, and Zoltán Toroczkai Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13661–13665. Published online 2000 November 21. PMCID: PMC17632 Chemistry Structural basis of the abscess-modulating polysaccharide A2 from
Bacteroides fragilis Ying Wang, Wiltrud M. Kalka-Moll, Michael H. Roehrl, and Dennis L. Kasper Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13478–13483. PMCID: PMC17600 Transformations in methane hydrates I-Ming Chou, Anurag Sharma, Robert C. Burruss, Jinfu Shu, Ho-kwang Mao, Russell J. Hemley, Alexander F. Goncharov, Laura A. Stern, and Stephen H. Kirby Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13484–13487. Published online 2000 November 21. PMCID: PMC17601 Genomewide studies of histone deacetylase function in yeast Bradley E. Bernstein, Jeffrey K. Tong, and Stuart L. Schreiber Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13708–13713. Published online 2000 November 28. PMCID: PMC17640 Engineering Microfluidic tectonics: A comprehensive construction platform for
microfluidic systems David J. Beebe, Jeffrey S. Moore, Qing Yu, Robin H. Liu, Mary L. Kraft, Byung-Ho Jo, and Chelladurai Devadoss Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13488–13493. Published online 2000 November 21. PMCID: PMC17602 Physics From the Cover: Elasticity of MgO and a primary pressure scale to 55 GPa Chang-Sheng Zha, Ho-kwang Mao, and Russell J. Hemley Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13494–13499. Published online 2000 November 28. PMCID: PMC17603 Biological Sciences Agricultural Sciences Predicting durability of a disease resistance gene based on an
assessment of the fitness loss and epidemiological consequences of
avirulence gene mutation Casiana M. Vera Cruz, Jianfa Bai, Isabelita Oña, Hei Leung, Rebecca J. Nelson, Twng-Wah Mew, and Jan E. Leach Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13500–13505. Published online 2000 November 28. PMCID: PMC17604 Anthropology Diet and the evolution of the earliest human ancestors Mark F. Teaford and Peter S. Ungar Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13506–13511. Published online 2000 November 28. PMCID: PMC17605 Applied Biological Sciences Improved barley broiler feed with transgenic malt containing
heat-stable (1,3–1,4)-β-glucanase Diter von Wettstein, Galina Mikhaylenko, John A. Froseth, and C. Gamini Kannangara Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13512–13517. PMCID: PMC17606 Biochemistry Protein folding and unfolding in microseconds to nanoseconds by
experiment and simulation Ugo Mayor, Christopher M. Johnson, Valerie Daggett, and Alan R. Fersht Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13518–13522. Published online 2000 November 21. PMCID: PMC17607 Palmitoylation of the HIV-1 envelope glycoprotein is critical for
viral infectivity Itay Rousso, Mark B. Mixon, Benjamin K. Chen, and Peter S. Kim Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13523–13525. Published online 2000 November 28. PMCID: PMC17608 Enzyme mimicry by the antiidiotypic antibody approach Alexander V. Kolesnikov, Arina V. Kozyr, Elena S. Alexandrova, Frédéric Koralewski, Alexander V. Demin, Mikhail I. Titov, Bérangère Avalle, Alfonso Tramontano, Sudhir Paul, Daniel Thomas, Alexander G. Gabibov, and Alain Friboulet Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13526–13531. Published online 2000 November 28. PMCID: PMC17609 The Zα domain of the editing enzyme dsRNA adenosine deaminase
binds left-handed Z-RNA as well as Z-DNA Bernard A. Brown, II, Ky Lowenhaupt, Christina M. Wilbert, Eugene
B. Hanlon, and Alexander Rich Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13532–13536. Published online 2000 November 21. PMCID: PMC17610 A continuous assay for DNA cleavage: The application of “break
lights” to enediynes, iron-dependent agents, and nucleases John B. Biggins, James R. Prudent, David J. Marshall, Mark Ruppen, and Jon S. Thorson Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13537–13542. Published online 2000 November 28. PMCID: PMC17611 An autocatalytic mechanism of protein nitrosylation Andrey Nedospasov, Ruslan Rafikov, Natalya Beda, and Evgeny Nudler Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13543–13548. Published online 2000 November 28. PMCID: PMC17612 Regulation of somatic growth by the p160 coactivator p/CIP Zhiyong Wang, David W. Rose, Ola Hermanson, Forrest Liu, Thomas Herman, Wei Wu, Daniel Szeto, Anatoli Gleiberman, Anna Krones, Katherine Pratt, Ron Rosenfeld, Christopher K. Glass, and Michael G. Rosenfeld Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13549–13554. Published online 2000 November 21. PMCID: PMC17613 The mechanism of substrate (aglycone) specificity in
β-glucosidases is revealed by crystal structures of mutant maize
β-glucosidase-DIMBOA, -DIMBOAGlc, and -dhurrin complexes Mirjam Czjzek, Muzaffer Cicek, Véronique Zamboni, David R. Bevan, Bernard Henrissat, and Asim Esen Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13555–13560. PMCID: PMC17614 Crystal structures of photosynthetic reaction center and
high-potential iron-sulfur protein from Thermochromatium
tepidum: Thermostability and electron transfer Terukazu Nogi, Insan Fathir, Masayuki Kobayashi, Tsunenori Nozawa, and Kunio Miki Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13561–13566. Published online 2000 November 28. PMCID: PMC17615 Zinc plays a key role in human and bacterial GTP
cyclohydrolase I Günter Auerbach, Anja Herrmann, Andreas Bracher, Gerd Bader, Markus Gütlich, Markus Fischer, Martin Neukamm, Marta Garrido-Franco, John Richardson, Herbert Nar, Robert Huber, and Adelbert Bacher Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13567–13572. Published online 2000 November 21. PMCID: PMC17616 Molecular basis for discriminating between normal and damaged
bases by the human alkyladenine glycosylase, AAG Albert Y. Lau, Michael D. Wyatt, Brian J. Glassner, Leona D. Samson, and Tom Ellenberger Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13573–13578. PMCID: PMC17617 Identification of the residues in the Myb domain of maize C1 that
specify the interaction with the bHLH cofactor R Erich Grotewold, Manuel B. Sainz, Laura Tagliani, J. Marcela Hernandez, Ben Bowen, and Vicki L. Chandler Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13579–13584. Published online 2000 November 28. PMCID: PMC17618 Coevolution of transcriptional and allosteric regulation at the
chorismate metabolic branch point of
Saccharomyces cerevisiae Sven Krappmann, William N. Lipscomb, and Gerhard H. Braus Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13585–13590. Published online 2000 November 28. PMCID: PMC17619 Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane
2α-O-benzoyltransferase cDNA from Taxus
and functional expression in Escherichia coli Kevin Walker and Rodney Croteau Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13591–13596. Published online 2000 November 28. PMCID: PMC17620 Biophysics Aβ amyloid fibrils possess a core structure highly resistant to
hydrogen exchange Indu Kheterpal, Shaolian Zhou, Kelsey D. Cook, and Ronald Wetzel Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13597–13601. Published online 2000 November 21. PMCID: PMC17621 Structural insights into the binding of cardiac glycosides to the
digitalis receptor revealed by solid-state NMR David A. Middleton, Saffron Rankin, Mikael Esmann, and Anthony Watts Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13602–13607. Published online 2000 November 28. PMCID: PMC17622 Global structure and mechanical properties of a 10-bp nucleosome
positioning motif M. Roychoudhury, A. Sitlani, J. Lapham, and D. M. Crothers Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13608–13613. Published online 2000 November 28. PMCID: PMC17623 Three-helix-bundle protein in a Ramachandran model Anders Irbäck, Fredrik Sjunnesson, and Stefan Wallin Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13614–13618. Published online 2000 November 28. PMCID: PMC17624 Cell Biology Glucose depletion causes haploid invasive growth in yeast Paul J. Cullen and George F. Sprague, Jr. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13619–13624. Published online 2000 November 28. PMCID: PMC17625 Postnatal human dental pulp stem cells (DPSCs) in
vitro and in vivo S. Gronthos, M. Mankani, J. Brahim, P. Gehron Robey, and S. Shi Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13625–13630. Published online 2000 November 21. PMCID: PMC17626 IFNα/β promotes cell survival by
activating NF-κB Chuan He Yang, Aruna Murti, Susan R. Pfeffer, Leela Basu, Jong G. Kim, and Lawrence M. Pfeffer Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13631–13636. Published online 2000 November 28. PMCID: PMC17627 Tyrosine phosphorylation of p97 regulates transitional
endoplasmic reticulum assembly in vitro Christine Lavoie, Eric Chevet, Line Roy, Nicholas K. Tonks, Ali Fazel, Barry I. Posner, Jacques Paiement, and John J. M. Bergeron Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13637–13642. Published online 2000 November 21. PMCID: PMC17628 Active recycling of yeast Golgi mannosyltransferase complexes
through the endoplasmic reticulum Zlatko Todorow, Anne Spang, Edwin Carmack, John Yates, and Randy Schekman Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13643–13648. Published online 2000 November 28. PMCID: PMC17629 Mutation of a BRCT domain selectively disrupts DNA single-strand
break repair in noncycling Chinese hamster ovary cells David J. Moore, Richard M. Taylor, Paula Clements, and Keith W. Caldecott Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13649–13654. Published online 2000 November 28. PMCID: PMC17630 Developmental Biology Members of the HRT family of basic helix–loop–helix
proteins act as transcriptional repressors downstream of
Notch signaling Osamu Nakagawa, David G. McFadden, Masayo Nakagawa, Hiromi Yanagisawa, Tonghuan Hu, Deepak Srivastava, and Eric N. Olson Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13655–13660. Published online 2000 November 28. PMCID: PMC17631 Ecology Chaotic flow: The physics of species coexistence György Károlyi, Áron Péntek, István Scheuring, Tamás Tél, and Zoltán Toroczkai Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13661–13665. Published online 2000 November 21. PMCID: PMC17632 Predicting the local dynamics of epizootic rabies among raccoons
in the United States James E. Childs, Aaron T. Curns, Meghan E. Dey, Leslie A. Real, Lisa Feinstein, Ottar N. Bjørnstad, and John W. Krebs Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13666–13671. Published online 2000 November 7. PMCID: PMC17633 From the Cover: Riverine barriers and the geographic distribution of
Amazonian species Claude Gascon, Jay R. Malcolm, James L. Patton, Maria N. F. da Silva, James P. Bogart, Stephen C. Lougheed, Carlos A. Peres, Selvino Neckel, and Peter T. Boag Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13672–13677. Published online 2000 November 28. PMCID: PMC17634 Evolution A formicine in New Jersey Cretaceous amber (Hymenoptera:
Formicidae) and early evolution of the ants David Grimaldi and Donat Agosti Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13678–13683. Published online 2000 November 14. PMCID: PMC17635 Eumetazoan fossils in terminal Proterozoic phosphorites? Shuhai Xiao, Xunlai Yuan, and Andrew H. Knoll Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13684–13689. Published online 2000 November 28. PMCID: PMC17636 Testing a biosynthetic theory of the genetic code: Fact or
artifact? Terres A. Ronneberg, Laura F. Landweber, and Stephen J. Freeland Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13690–13695. Published online 2000 November 21. PMCID: PMC17637 Genetics Inositol polyphosphate 4-phosphatase type I regulates cell growth
downstream of transcription factor GATA-1 Paresh Vyas, F. Anderson Norris, Raji Joseph, Philip W. Majerus, and Stuart H. Orkin Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13696–13701. Published online 2000 November 21. PMCID: PMC17638 Illegitimate Cre-dependent chromosome rearrangements in
transgenic mouse spermatids Edward E. Schmidt, Deborah S. Taylor, Justin R. Prigge, Sheila Barnett, and Mario R. Capecchi Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13702–13707. Published online 2000 November 21. PMCID: PMC17639 Genomewide studies of histone deacetylase function in yeast Bradley E. Bernstein, Jeffrey K. Tong, and Stuart L. Schreiber Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13708–13713. Published online 2000 November 28. PMCID: PMC17640 From the Cover: Adeno-associated virus vector carrying human minidystrophin genes
effectively ameliorates muscular dystrophy in mdx
mouse model Bing Wang, Juan Li, and Xiao Xiao Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13714–13719. Published online 2000 November 28. PMCID: PMC17641 Targeted modification and transportation of cellular proteins Pierre Colas, Barak Cohen, Paul Ko Ferrigno, Pamela A. Silver, and Roger Brent Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13720–13725. PMCID: PMC17642 Genome-wide study of aging and oxidative stress response in
Drosophila melanogaster Sige Zou, Sarah Meadows, Linda Sharp, Lily Y. Jan, and Yuh Nung Jan Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13726–13731. Published online 2000 November 28. PMCID: PMC17643 A new screen for protein interactions reveals that the
Saccharomyces cerevisiae high mobility group proteins
Nhp6A/B are involved in the regulation of the GAL1 promoter Heike Laser, Christine Bongards, Jutta Schüller, Stephanie Heck, Nils Johnsson, and Norbert Lehming Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13732–13737. Published online 2000 November 28. PMCID: PMC17644 A novel type of RNA editing occurs in the mitochondrial tRNAs of
the centipede Lithobius forficatus Dennis V. Lavrov, Wesley M. Brown, and Jeffrey L. Boore Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13738–13742. Published online 2000 November 28. PMCID: PMC17645 A prokaryote and human tRNA synthetase provide an essential RNA
splicing function in yeast mitochondria Fariba Houman, Seung Bae Rho, Jiansu Zhang, Xiaoyu Shen, Chien-Chia Wang, Paul Schimmel, and Susan A. Martinis Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13743–13748. Published online 2000 November 21. PMCID: PMC17646 Protein kinase activity of Tel1p and Mec1p, two
Saccharomyces cerevisiae proteins related to the
human ATM protein kinase Julia C. Mallory and Thomas D. Petes Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13749–13754. Published online 2000 November 28. PMCID: PMC17647 3′ deletions cause aniridia by preventing PAX6 gene expression James D. Lauderdale, Jonathan S. Wilensky, Edward R. Oliver, David S. Walton, and Tom Glaser Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13755–13759. Published online 2000 November 21. PMCID: PMC17648 Gene correction in hematopoietic progenitor cells by
homologous recombination Seigo Hatada, Koji Nikkuni, Stuart A. Bentley, Suzanne Kirby, and Oliver Smithies Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13807–13811. Published online 2000 November 21. PMCID: PMC17657 Drug-resistant Drosophila indicate glutamate-gated
chloride channels are targets for the antiparasitics nodulisporic acid
and ivermectin Nanci S. Kane, Birgit Hirschberg, Su Qian, David Hunt, Brande Thomas, Richard Brochu, Steven W. Ludmerer, Yingcong Zheng, McHardy Smith, Joseph P. Arena, Charles J. Cohen, Dennis Schmatz, Jeffrey Warmke, and Doris F. Cully Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13949–13954. Published online 2000 November 28. PMCID: PMC17681 Immunology Diversity of T cell repertoire shaped by a single peptide ligand
is critically affected by its amino acid residue at a T cell receptor contact Yoshinori Fukui, Takamasa Oono, Jean-Pierre Cabaniols, Kazuki Nakao, Katsuiku Hirokawa, Ayumi Inayoshi, Terukazu Sanui, Jean Kanellopoulos, Eiko Iwata, Mayuko Noda, Motoya Katsuki, Philippe Kourilsky, and Takehiko Sasazuki Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13760–13765. Published online 2000 November 21. PMCID: PMC17649 The repertoire for pattern recognition of pathogens by the innate
immune system is defined by cooperation between Toll-like receptors Adrian Ozinsky, David M. Underhill, Jason D. Fontenot, Adeline M. Hajjar, Kelly D. Smith, Christopher B. Wilson, Lea Schroeder, and Alan Aderem Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13766–13771. Published online 2000 November 28. PMCID: PMC17650 A family of peptidoglycan recognition proteins in the fruit fly
Drosophila melanogaster Thomas Werner, Gang Liu, Daiwu Kang, Sophia Ekengren, Håkan Steiner, and Dan Hultmark Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13772–13777. PMCID: PMC17651 Impact of HIV-1 infection and highly active antiretroviral
therapy on the kinetics of CD4+ and CD8+ T
cell turnover in HIV-infected patients Richard A. Lempicki, Joseph A. Kovacs, Michael W. Baseler, Joseph W. Adelsberger, Robin L. Dewar, Ven Natarajan, Marjorie C. Bosche, Julia A. Metcalf, Randy A. Stevens, Laurie A. Lambert, W. Gregory Alvord, Michael A. Polis, Richard T. Davey, Dimiter S. Dimitrov, and H. Clifford Lane Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13778–13783. Published online 2000 November 28. PMCID: PMC17652 Transgenic expression of the coxsackie/adenovirus receptor
enables adenoviral-mediated gene delivery in naïve T cells Yisong Y. Wan, Ronald P. Leon, Reinhard Marks, Candace M. Cham, Jerome Schaack, Thomas F. Gajewski, and James DeGregori Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13784–13789. Published online 2000 November 28. PMCID: PMC17653 MHC I-dependent antigen presentation is inhibited by poliovirus
protein 3A Stephen B. Deitz, Dana A. Dodd, Stewart Cooper, Peter Parham, and Karla Kirkegaard Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13790–13795. Published online 2000 November 28. PMCID: PMC17654 Medical Sciences Haploinsufficiency of Snf5 (integrase interactor 1) predisposes
to malignant rhabdoid tumors in mice Charles W. M. Roberts, Shelly A. Galusha, Máirín E. McMenamin, Christopher D. M. Fletcher, and Stuart H. Orkin Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13796–13800. Published online 2000 November 28. PMCID: PMC17655 Adeno-associated viral vector-mediated vascular endothelial
growth factor gene transfer induces neovascular formation in
ischemic heart Hua Su, Ronghua Lu, and Yuet Wai Kan Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13801–13806. Published online 2000 November 28. PMCID: PMC17656 Gene correction in hematopoietic progenitor cells by
homologous recombination Seigo Hatada, Koji Nikkuni, Stuart A. Bentley, Suzanne Kirby, and Oliver Smithies Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13807–13811. Published online 2000 November 21. PMCID: PMC17657 Higher macrophage inflammatory protein (MIP)-1α and MIP-1β
levels from CD8+ T cells are associated with
asymptomatic HIV-1 infection Fiorenza Cocchi, Anthony L. DeVico, Robert Yarchoan, Robert Redfield, Farley Cleghorn, William A. Blattner, Alfredo Garzino-Demo, Sandra Colombini-Hatch, David Margolis, and Robert C. Gallo Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13812–13817. Published online 2000 November 28. PMCID: PMC17658 Functional muscle ischemia in neuronal nitric oxide
synthase-deficient skeletal muscle of children with Duchenne
muscular dystrophy Mikael Sander, Bahman Chavoshan, Shannon A. Harris, Susan T. Iannaccone, James T. Stull, Gail D. Thomas, and Ronald G. Victor Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13818–13823. Published online 2000 November 21. PMCID: PMC17659 Two distinct signaling pathways in hair cycle induction:
Stat3-dependent and -independent pathways Shigetoshi Sano, Masahiro Kira, Satoshi Takagi, Kunihiko Yoshikawa, Junji Takeda, and Satoshi Itami Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13824–13829. Published online 2000 November 21. PMCID: PMC17660 Increased atherosclerosis in hyperlipidemic mice deficient in
α-tocopherol transfer protein and vitamin E Yuko Terasawa, Zuleika Ladha, Scott W. Leonard, Jason D. Morrow, Dale Newland, David Sanan, Lester Packer, Maret G. Traber, and Robert V. Farese, Jr. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13830–13834. Published online 2000 November 28. PMCID: PMC17661 Pro-coagulant state resulting from high levels of soluble
P-selectin in blood Patrick André, Daqing Hartwell, Ingrid Hrachovinová, Simin Saffaripour, and Denisa D. Wagner Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13835–13840. Published online 2000 November 28. PMCID: PMC17662 A distinct glycoform of CD44 is an L-selectin ligand on human
hematopoietic cells Charles J. Dimitroff, Jack Y. Lee, Robert C. Fuhlbrigge, and Robert Sackstein Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13841–13846. Published online 2000 November 28. PMCID: PMC17663 Microbiology Structural basis of the abscess-modulating polysaccharide A2 from
Bacteroides fragilis Ying Wang, Wiltrud M. Kalka-Moll, Michael H. Roehrl, and Dennis L. Kasper Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13478–13483. PMCID: PMC17600 From the Cover: The transcriptional responses of respiratory epithelial cells to
Bordetella pertussis reveal host defensive and
pathogen counter-defensive strategies Christopher E. Belcher, Jörg Drenkow, Bettina Kehoe, Thomas R. Gingeras, Nancy McNamara, Hassan Lemjabbar, Carol Basbaum, and David A. Relman Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13847–13852. Published online 2000 November 21. PMCID: PMC17664 Recombinant bacillus Calmette–Guérin (BCG) vaccines
expressing the Mycobacterium tuberculosis 30-kDa major
secretory protein induce greater protective immunity against
tuberculosis than conventional BCG vaccines in a highly susceptible
animal model Marcus A. Horwitz, Günter Harth, Barbara Jane Dillon, and Saša Masleša-Galić Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13853–13858. Published online 2000 November 28. PMCID: PMC17665 Anopheles gambiae salivary gland proteins as
putative targets for blocking transmission of malaria parasites Justin D. G. Brennan, Melissa Kent, Ravi Dhar, Hisashi Fujioka, and Nirbhay Kumar Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13859–13864. Published online 2000 November 21. PMCID: PMC17666 Correlation between plasmid content and infectivity in
Borrelia burgdorferi Joye E. Purser and Steven J. Norris Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13865–13870. PMCID: PMC17667 A PPxY motif within the VP40 protein of Ebola virus interacts
physically and functionally with a ubiquitin ligase: Implications
for filovirus budding Ronald N. Harty, Melissa E. Brown, Guangli Wang, Jon Huibregtse, and Felicia P. Hayes Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13871–13876. Published online 2000 November 28. PMCID: PMC17668 Neurobiology Transplanted fetal striatum in Huntington's disease: Phenotypic
development and lack of pathology Thomas B. Freeman, Francesca Cicchetti, Robert A. Hauser, Terrence W. Deacon, Xiao-Jiang Li, Steven M. Hersch, G. Michael Nauert, Paul R. Sanberg, Jeffrey H. Kordower, Samuel Saporta, and Ole Isacson Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13877–13882. PMCID: PMC17669 Identification of a multipotent astrocytic stem cell in the
immature and adult mouse brain Eric D. Laywell, Pasko Rakic, Valery G. Kukekov, Eric C. Holland, and Dennis A. Steindler Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13883–13888. Published online 2000 November 28. PMCID: PMC17670 The activation mechanism of rat vanilloid receptor 1 by capsaicin
involves the pore domain and differs from the activation by either acid
or heat J. M. Welch, S. A. Simon, and P. H. Reinhart Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13889–13894. Published online 2000 November 28. PMCID: PMC17671 Mechanism-based discovery of ligands that counteract inhibition
of the nicotinic acetylcholine receptor by cocaine and MK-801 George P. Hess, Henning Ulrich, Hans-Georg Breitinger, Li Niu, Armanda M. Gameiro, Christof Grewer, Sanjay Srivastava, Joseph E. Ippolito, Sean M. Lee, Vasanthi Jayaraman, and Susan E. Coombs Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13895–13900. Published online 2000 November 28. PMCID: PMC17672 Caspase-1 and -3 are sequentially activated in motor neuron death
in Cu,Zn superoxide dismutase-mediated familial amyotrophic
lateral sclerosis Piera Pasinelli, Megan K. Houseweart, Robert H. Brown, Jr., and Don W. Cleveland Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13901–13906. Published online 2000 November 28. PMCID: PMC17673 Disruption of the neural response to rapid acoustic stimuli in
dyslexia: Evidence from functional MRI E. Temple, R. A. Poldrack, A. Protopapas, S. Nagarajan, T. Salz, P. Tallal, M. M. Merzenich, and J. D. E. Gabrieli Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13907–13912. Published online 2000 November 28. PMCID: PMC17674 Phototransduction in transgenic mice after targeted deletion of
the rod transducin α-subunit P. D. Calvert, N. V. Krasnoperova, A. L. Lyubarsky, T. Isayama, M. Nicoló, B. Kosaras, G. Wong, K. S. Gannon, R. F. Margolskee, R. L. Sidman, E. N. Pugh, Jr., C. L. Makino, and J. Lem Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13913–13918. Published online 2000 November 28. PMCID: PMC17675 What is a moment? “Cortical” sensory integration over a
brief interval J. J. Hopfield and Carlos D. Brody Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13919–13924. Published online 2000 November 28. PMCID: PMC17676 γ-Aminobutyric acid, acting through γ-aminobutyric acid type
A receptors, inhibits the biosynthesis of neurosteroids in the frog
hypothalamus J. L. Do-Rego, G. A. Mensah-Nyagan, D. Beaujean, D. Vaudry, W. Sieghart, V. Luu-The, G. Pelletier, and H. Vaudry Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13925–13930. Published online 2000 November 21. PMCID: PMC17677 The neural representation of postural control in humans Hans-Otto Karnath, Susanne Ferber, and Johannes Dichgans Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13931–13936. Published online 2000 November 21. PMCID: PMC17678 Prion infection impairs the cellular response to
oxidative stress Ollivier Milhavet, Hilary E. M. McMahon, Walid Rachidi, Noriyuki Nishida, Shigeru Katamine, Alain Mangé, Marie Arlotto, Danielle Casanova, Jacqueline Riondel, Alain Favier, and Sylvain Lehmann Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13937–13942. Published online 2000 November 28. PMCID: PMC17679 Molecular determinants of the functional interaction between
syntaxin and N-type Ca2+ channel gating Ilya Bezprozvanny, Pingyu Zhong, Richard H. Scheller, and Richard W. Tsien Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13943–13948. Published online 2000 November 21. PMCID: PMC17680 Drug-resistant Drosophila indicate glutamate-gated
chloride channels are targets for the antiparasitics nodulisporic acid
and ivermectin Nanci S. Kane, Birgit Hirschberg, Su Qian, David Hunt, Brande Thomas, Richard Brochu, Steven W. Ludmerer, Yingcong Zheng, McHardy Smith, Joseph P. Arena, Charles J. Cohen, Dennis Schmatz, Jeffrey Warmke, and Doris F. Cully Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13949–13954. Published online 2000 November 28. PMCID: PMC17681 SNARE proteins contribute to calcium cooperativity of
synaptic transmission Bryan A. Stewart, Mahmood Mohtashami, William S. Trimble, and Gabrielle L. Boulianne Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13955–13960. Published online 2000 November 28. PMCID: PMC17682 From the Cover: Speech-like cerebral activity in profoundly deaf people
processing signed languages: Implications for the neural basis of human language Laura Ann Petitto, Robert J. Zatorre, Kristine Gauna, E. J. Nikelski, Deanna Dostie, and Alan C. Evans Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13961–13966. PMCID: PMC17683 The GABAB receptor interacts directly with the
related transcription factors CREB2 and ATFx Julia H. White, R. A. Jeffrey McIllhinney, Alan Wise, Francisco Ciruela, Wai-Yee Chan, Piers C. Emson, Andrew Billinton, and Fiona H. Marshall Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13967–13972. Published online 2000 November 21. PMCID: PMC17684 Pharmacology SST3-selective potent peptidic somatostatin receptor
antagonists Jean Claude Reubi, Jean-Claude Schaer, Sandra Wenger, Carl Hoeger, Judit Erchegyi, Beatrice Waser, and Jean Rivier Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13973–13978. Published online 2000 November 28. PMCID: PMC17685 Plant Biology Identification of the residues in the Myb domain of maize C1 that
specify the interaction with the bHLH cofactor R Erich Grotewold, Manuel B. Sainz, Laura Tagliani, J. Marcela Hernandez, Ben Bowen, and Vicki L. Chandler Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13579–13584. Published online 2000 November 28. PMCID: PMC17618 Genetic evidence for the in planta role of
phloem-specific plasma membrane sucrose transporters Jennifer R. Gottwald, Patrick J. Krysan, Jeffery C. Young, Ray F. Evert, and Michael R. Sussman Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13979–13984. Published online 2000 November 21. PMCID: PMC17686 Novel features of the XRN-family in Arabidopsis:
Evidence that AtXRN4, one of several orthologs of nuclear
Xrn2p/Rat1p, functions in the cytoplasm J. P. Kastenmayer and P. J. Green Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13985–13990. PMCID: PMC17687 Mutants of Arabidopsis defective in a
sequence-specific mRNA degradation pathway Mark A. Johnson, Miguel A. Pérez-Amador, Preetmoninder Lidder, and Pamela J. Green Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13991–13996. Published online 2000 November 21. PMCID: PMC17688 Psychology The ability to follow eye gaze and its emergence during
development in macaque monkeys P. F. Ferrari, E. Kohler, L. Fogassi, and V. Gallese Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13997–14002. Published online 2000 November 28. PMCID: PMC17689 Social Sciences Anthropology Population structure and history in East Asia Yuan-Chun Ding, Stephen Wooding, Henry C. Harpending, Han-Chang Chi, Hai-Peng Li, Yun-Xin Fu, Jun-Feng Pang, Yong-Gang Yao, Jing-Gong Xiang Yu, Robert Moyzis, and Ya-ping Zhang Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 14003–14006. Published online 2000 November 28. PMCID: PMC17690 Psychology From the Cover: Speech-like cerebral activity in profoundly deaf people
processing signed languages: Implications for the neural basis of human language Laura Ann Petitto, Robert J. Zatorre, Kristine Gauna, E. J. Nikelski, Deanna Dostie, and Alan C. Evans Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13961–13966. PMCID: PMC17683 Social Sciences INAUGURAL ARTICLE by a Recently Elected Academy Member: Institutional radicalization, the state, and the development
process in Africa Akin L. Mabogunje Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 14007–14014. Published online 2000 November 21. PMCID: PMC17691 Correction Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 14015. Published online 2000 November 28. PMCID: PMC56179 Corrects: Alexandre Hassanin, et al. Evolution of the recombination signal sequences in the Ig
heavy-chain variable region locus of mammals. Proc Natl Acad Sci U S A. 2000 October 10; 97(21): 11415–11420. |