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Volume 99(Suppl 4);  December 10, 2002
Colloquium Papers
Transmission of prions
C. Weissmann, M. Enari, P.-C. Klöhn, D. Rossi, and E. Flechsig
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16378–16383. doi: 10.1073/pnas.172403799.
PMCID: PMC139897
Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein
Herman K. Edskes and Reed B. Wickner
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16384–16391. doi: 10.1073/pnas.162349599.
PMCID: PMC139898
Interactions among prions and prion “strains” in yeast
Michael E. Bradley, Herman K. Edskes, Joo Y. Hong, Reed B. Wickner, and Susan W. Liebman
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16392–16399. doi: 10.1073/pnas.152330699.
PMCID: PMC139899
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay
Volker Heiser, Sabine Engemann, Wolfgang Bröcker, Ilona Dunkel, Annett Boeddrich, Stephanie Waelter, Eddi Nordhoff, Rudi Lurz, Nancy Schugardt, Susanne Rautenberg, Christian Herhaus, Gerhard Barnickel, Henning Böttcher, Hans Lehrach, and Erich E. Wanker
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16400–16406. doi: 10.1073/pnas.182426599.
PMCID: PMC139900
Chaperoning brain degeneration
Nancy M. Bonini
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16407–16411. doi: 10.1073/pnas.152330499.
PMCID: PMC139901
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity
Hideki Sakahira, Peter Breuer, Manajit K. Hayer-Hartl, and F. Ulrich Hartl
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16412–16418. doi: 10.1073/pnas.182426899.
PMCID: PMC139902
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases
Fabrizio Chiti, Martino Calamai, Niccolò Taddei, Massimo Stefani, Giampietro Ramponi, and Christopher M. Dobson
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16419–16426. doi: 10.1073/pnas.212527999.
PMCID: PMC139903
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity
Per Hammarström, Xin Jiang, Amy R. Hurshman, Evan T. Powers, and Jeffery W. Kelly
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16427–16432. doi: 10.1073/pnas.202495199.
PMCID: PMC139904
The insulation of genes from external enhancers and silencing chromatin
Bonnie Burgess-Beusse, Catherine Farrell, Miklos Gaszner, Michael Litt, Vesco Mutskov, Felix Recillas-Targa, Melanie Simpson, Adam West, and Gary Felsenfeld
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16433–16437. doi: 10.1073/pnas.162342499.
PMCID: PMC139905
Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast
Ken-ichi Noma and Shiv I. S. Grewal
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16438–16445. doi: 10.1073/pnas.182436399.
PMCID: PMC139906
Changes in the middle region of Sup35 profoundly alter the nature of epigenetic inheritance for the yeast prion [PSI+]
Jia-Jia Liu, Neal Sondheimer, and Susan L. Lindquist
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16446–16453. doi: 10.1073/pnas.252652099.
PMCID: PMC139907
Heritable chromatin structure: Mapping “memory” in histones H3 and H4
Christine M. Smith, Zara W. Haimberger, Catherine O. Johnson, Alex J. Wolf, Philip R. Gafken, Zhongli Zhang, Mark R. Parthun, and Daniel E. Gottschling
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16454–16461. doi: 10.1073/pnas.182424999.
PMCID: PMC139908
Does heterochromatin protein 1 always follow code?
Yuhong Li, Dawn A. Kirschmann, and Lori L. Wallrath
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16462–16469. doi: 10.1073/pnas.162371699.
PMCID: PMC139909
Self-perpetuating epigenetic pili switches in bacteria
Aaron Hernday, Margareta Krabbe, Bruce Braaten, and David Low
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16470–16476. doi: 10.1073/pnas.182427199.
PMCID: PMC139910
Histone H3 variants specify modes of chromatin assembly
Kami Ahmad and Steven Henikoff
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16477–16484. doi: 10.1073/pnas.172403699.
PMCID: PMC139911
Induction and maintenance of nonsymmetrical DNA methylation in Neurospora
Eric U. Selker, Michael Freitag, Gregory O. Kothe, Brian S. Margolin, Michael R. Rountree, C. David Allis, and Hisashi Tamaru
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16485–16490. doi: 10.1073/pnas.182427299.
PMCID: PMC139912
Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes
Xiaofeng Cao and Steven E. Jacobsen
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16491–16498. doi: 10.1073/pnas.162371599.
PMCID: PMC139913
RNA-directed DNA methylation in Arabidopsis
Werner Aufsatz, M. Florian Mette, Johannes van der Winden, Antonius J. M. Matzke, and Marjori Matzke
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16499–16506. doi: 10.1073/pnas.162371499.
PMCID: PMC139914
Introduction
Self-perpetuating structural states in biology, disease, and genetics
Susan L. Lindquist and Steven Henikoff
Proc Natl Acad Sci U S A. 2002 December 10; 99(Suppl 4): 16377. doi: 10.1073/pnas.212504699.
PMCID: PMC139896
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