| | This journal provides immediate access to some articles. Commentaries Systemic wound signaling in plants: A new perception Clarence A. Ryan and Daniel S. Moura PMCID: PMC124432 Push or pull? Teams of motor proteins have it both ways Thomas Duke PMCID: PMC124433 Sea level is rising: Do we know why? Mark F. Meier and John M. Wahr PMCID: PMC124434 Progress in rapid screening of Bacillus anthracis lethal factor activity Michèle Mock and Bernard P. Roques PMCID: PMC124435 Cooperativity between bacterial chemotaxis receptors Joseph J. Falke PMCID: PMC124436 Physical Sciences Chemistry Microrheometry of semiflexible actin networks through enforced single-filament reptation: Frictional coupling and heterogeneities in entangled networks M. A. Dichtl and E. Sackmann PMCID: PMC124437 From the Cover:
Drying-induced hydrophobic polymer collapse Pieter Rein ten Wolde and David Chandler PMCID: PMC124438 Gaussian fluctuations and linear response in an electron transfer protein Thomas Simonson PMCID: PMC124439 Geophysics From the Cover:
Twentieth century sea level: An enigma Walter Munk PMCID: PMC124440 Origin of supposedly biogenic magnetite in the Martian meteorite Allan Hills 84001 David J. Barber and Edward R. D. Scott PMCID: PMC124441 Statistics Selection bias in gene extraction on the basis of microarray gene-expression data Christophe Ambroise and Geoffrey J. McLachlan PMCID: PMC124442 Diagnosis of multiple cancer types by shrunken centroids of gene expression Robert Tibshirani, Trevor Hastie, Balasubramanian Narasimhan, and Gilbert Chu PMCID: PMC124443 Biological Sciences Applied Biological Sciences Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus Hildegard Etz, Duc Bui Minh, Tamás Henics, Agnieszka Dryla, Birgit Winkler, Christine Triska, Aoife P. Boyd, Johannes Söllner, Walter Schmidt, Uwe von Ahsen, Michael Buschle, Steven R. Gill, James Kolonay, Hanif Khalak, Claire M. Fraser, Alexander von Gabain, Eszter Nagy, and Andreas Meinke PMCID: PMC124444 Biochemistry Structure-based design of mutant Methanococcus jannaschii tyrosyl-tRNA synthetase for incorporation of O-methyl-l-tyrosine Deqiang Zhang, Nagarajan Vaidehi, William A. Goddard, III, Joseph F. Danzer, and Derek Debe PMCID: PMC124445 Telomerase recognizes its template by using an adjacent RNA motif Michael C. Miller and Kathleen Collins PMCID: PMC124446 Structure of 2C-methyl-d-erythritol 2,4- cyclodiphosphate synthase: An essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development Lauris E. Kemp, Charles S. Bond, and William N. Hunter PMCID: PMC124447 Directed evolution of novel polymerase activities: Mutation of a DNA polymerase into an efficient RNA polymerase Gang Xia, Liangjing Chen, Takashi Sera, Ming Fa, Peter G. Schultz, and Floyd E. Romesberg PMCID: PMC124448 From the Cover:
A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease Richard T. Cummings, Scott P. Salowe, Barry R. Cunningham, Judyann Wiltsie, Young Whan Park, Lisa M. Sonatore, Douglas Wisniewski, Cameron M. Douglas, Jeffrey D. Hermes, and Edward M. Scolnick PMCID: PMC124449 The 1.9-Å crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link Manuel E. Than, Stefan Henrich, Robert Huber, Albert Ries, Karlheinz Mann, Klaus Kühn, Rupert Timpl, Gleb P. Bourenkov, Hans D. Bartunik, and Wolfram Bode PMCID: PMC124450 Changing the lactose permease of Escherichia coli into a galactose-specific symporter Lan Guan, Miklós Sahin-Tóth, and H. Ronald Kaback PMCID: PMC124451 Toward development of a screen to identify randomly encoded, foldable sequences Yoshihisa Hagihara and Peter S. Kim PMCID: PMC124452 Looped out and perpendicular: Deformation of Watson–Crick base pair associated with actinomycin D binding Shan-Ho Chou, Ko-Hsin Chin, and Fu-Ming Chen PMCID: PMC124453 Refined molecular hinge between allosteric and catalytic domain determines allosteric regulation and stability of fungal chorismate mutase Kerstin Helmstaedt, Gabriele Heinrich, William N. Lipscomb, and Gerhard H. Braus PMCID: PMC124454 Headpiece domain of dematin is required for the stability of the erythrocyte membrane Richie Khanna, Seon H. Chang, Shaida Andrabi, Mohammad Azam, Anthony Kim, Alicia Rivera, Carlo Brugnara, Philip S. Low, Shih-Chun Liu, and Athar H. Chishti PMCID: PMC124455 Inhibition of mitochondrial protein synthesis results in increased endothelial cell susceptibility to nitric oxide-induced apoptosis Anup Ramachandran, Douglas R. Moellering, Erin Ceaser, Sruti Shiva, Jun Xu, and Victor Darley-Usmar PMCID: PMC124456 The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation Diane R. Wonsey, Karen I. Zeller, and Chi V. Dang PMCID: PMC124457 The aflatoxin B1 formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma Maryann E. Smela, Michelle L. Hamm, Paul T. Henderson, Constance M. Harris, Thomas M. Harris, and John M. Essigmann PMCID: PMC124458 Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes Jay A. Grobler, Kara Stillmock, Binghua Hu, Marc Witmer, Peter Felock, Amy S. Espeseth, Abigail Wolfe, Melissa Egbertson, Michele Bourgeois, Jeffrey Melamed, John S. Wai, Steve Young, Joseph Vacca, and Daria J. Hazuda PMCID: PMC124459 Complete pathway for protein disulfide bond formation encoded by poxviruses Tatiana G. Senkevich, Christine L. White, Eugene V. Koonin, and Bernard Moss PMCID: PMC124460 Preferential binding of ATR protein to UV-damaged DNA Keziban Ünsal-Kaçmaz, Alexander M. Makhov, Jack D. Griffith, and Aziz Sancar PMCID: PMC124461 The iscS gene is essential for the biosynthesis of 2-selenouridine in tRNA and the selenocysteine-containing formate dehydrogenase H Hisaaki Mihara, Shin-ichiro Kato, Gerard M. Lacourciere, Thressa C. Stadtman, Robert A. J. D. Kennedy, Tatsuo Kurihara, Umechiyo Tokumoto, Yasuhiro Takahashi, and Nobuyoshi Esaki PMCID: PMC124462 FRS2α attenuates FGF receptor signaling by Grb2- mediated recruitment of the ubiquitin ligase Cbl Andy Wong, Betty Lamothe, Arnold Lee, Joseph Schlessinger, and Irit Lax PMCID: PMC124463 The OhrR repressor senses organic hydroperoxides by reversible formation of a cysteine-sulfenic acid derivative Mayuree Fuangthong and John D. Helmann PMCID: PMC124464 Biophysics Bidirectional cooperative motion of molecular motors M. Badoual, F. Jülicher, and J. Prost PMCID: PMC124465 Key role of proline L209 in connecting the distant quinone pockets in the reaction center of Rhodobacter sphaeroides J. Tandori, P. Maroti, E. Alexov, P. Sebban, and L. Baciou PMCID: PMC124466 CLOUDS, a protocol for deriving a molecular proton density via NMR Alexander Grishaev and Miguel Llinás PMCID: PMC124467 Protein structure elucidation from NMR proton densities Alexander Grishaev and Miguel Llinás PMCID: PMC124468 Molecular dynamics simulations of protein folding from the transition state Jörg Gsponer and Amedeo Caflisch PMCID: PMC124469 Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks Timothy H. Bayburt and Stephen G. Sligar PMCID: PMC124470 Energetics of glycerol conduction through aquaglyceroporin GlpF Morten Ø. Jensen, Sanghyun Park, Emad Tajkhorshid, and Klaus Schulten PMCID: PMC124471 Cell Biology Identification of β-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA Martin Olbrot, Jonathan Rud, Larry G. Moss, and Arun Sharma PMCID: PMC124472 A flagellar K+-dependent Na+/Ca2+ exchanger keeps Ca2+ low in sea urchin spermatozoa Yi-Hsien Su and Victor D. Vacquier PMCID: PMC124473 Identification of four candidate cGMP targets in Dictyostelium Jonathan M. Goldberg, Leonard Bosgraaf, Peter J. M. Van Haastert, and Janet L. Smith PMCID: PMC124474 The δ subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surface Noriyuki Nishimura, Helen Plutner, Klaus Hahn, and William E. Balch PMCID: PMC124475 Dynamic assembly of MinD on phospholipid vesicles regulated by ATP and MinE Zonglin Hu, Edward P. Gogol, and Joe Lutkenhaus PMCID: PMC124476 Endosomal localization and function of sorting nexin 1 Qi Zhong, Cheri S. Lazar, Hélène Tronchère, Trey Sato, Timo Meerloo, Michele Yeo, Zhou Songyang, Scott D. Emr, and Gordon N. Gill PMCID: PMC124477 Inositol hexakisphosphate promotes dynamin I- mediated endocytosis Marianne Høy, Alexander M. Efanov, Alejandro M. Bertorello, Sergei V. Zaitsev, Hervør L. Olsen, Krister Bokvist, Barbara Leibiger, Ingo B. Leibiger, Jean Zwiller, Per-Olof Berggren, and Jesper Gromada PMCID: PMC124478 Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea Alice Fabarius, Andreas Willer, George Yerganian, Ruediger Hehlmann, and Peter Duesberg PMCID: PMC124479 The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine José L. Crespo, Ted Powers, Brian Fowler, and Michael N. Hall PMCID: PMC124480 The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer Michael A. Rycyzyn and Charles V. Clevenger PMCID: PMC124481 Clara cell impact in air-side activation of CFTR in small pulmonary airways Hasan Kulaksiz, Andreas Schmid, Matthias Hönscheid, Annette Ramaswamy, and Yalcin Cetin PMCID: PMC124482 Developmental Biology Genome-wide identification of tissue-specific enhancers in the Ciona tadpole Naoe Harafuji, David N. Keys, and Michael Levine PMCID: PMC124483 BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma Dmitri I. Loukinov, Elena Pugacheva, Sergei Vatolin, Svetlana D. Pack, Hanlim Moon, Igor Chernukhin, Poonam Mannan, Erik Larsson, Chandrasekhar Kanduri, Alexander A. Vostrov, Hengmi Cui, Emily L. Niemitz, John E. J. Rasko, France M. Docquier, Malathi Kistler, Joseph J. Breen, Zhengping Zhuang, Wolfgang W. Quitschke, Rainer Renkawitz, Elena M. Klenova, Andrew P. Feinberg, Rolf Ohlsson, Herbert C. Morse, III, and Victor V. Lobanenkov PMCID: PMC124484 Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform Sanjaya Singh, Rajnikant Mishra, Nelson A. Arango, Jian Min Deng, Richard R. Behringer, and Grady F. Saunders PMCID: PMC124485 Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1 Friedhelm Bladt, Anna Tafuri, Sigal Gelkop, Lowell Langille, and Tony Pawson PMCID: PMC124486 Ecology Mayolenes: Labile defensive lipids from the glandular hairs of a caterpillar (Pieris rapae) Scott R. Smedley, Frank C. Schroeder, Douglas B. Weibel, Jerrold Meinwald, Katie A. Lafleur, J. Alan Renwick, Ronald Rutowski, and Thomas Eisner PMCID: PMC124487 Evolution The genetics of maternal care: Direct and indirect genetic effects on phenotype in the dung beetle Onthophagus taurus John Hunt and Leigh W. Simmons PMCID: PMC124488 Laurasian migration explains Gondwanan disjunctions: Evidence from Malpighiaceae Charles C. Davis, Charles D. Bell, Sarah Mathews, and Michael J. Donoghue PMCID: PMC124489 The development of immunity in a social insect: Evidence for the group facilitation of disease resistance James F. A. Traniello, Rebeca B. Rosengaus, and Keely Savoie PMCID: PMC124490 Sex-ratio conflicts, kin selection, and the evolution of altruism Wladimir J. Alonso and Cynthia Schuck-Paim PMCID: PMC124491 The root of the angiosperms revisited Michael J. Zanis, Douglas E. Soltis, Pamela S. Soltis, Sarah Mathews, and Michael J. Donoghue PMCID: PMC124492 Anatomical and ecological constraints on Phanerozoic animal diversity in the marine realm Richard K. Bambach, Andrew H. Knoll, and J. John Sepkoski, Jr. PMCID: PMC124493 Genetics Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress Robert W. Sobol, David E. Watson, Jun Nakamura, F. Michael Yakes, Esther Hou, Julie K. Horton, Joseph Ladapo, Bennett Van Houten, James A. Swenberg, Kenneth R. Tindall, Leona D. Samson, and Samuel H. Wilson PMCID: PMC124494 Segregation distortion induced by wild-type RanGAP in Drosophila Ayumi Kusano, Cynthia Staber, and Barry Ganetzky PMCID: PMC124495 Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death Andrew R. Mendelsohn, Janice D. Hamer, Zhaoyuan Bill Wang, and Roger Brent PMCID: PMC124496 Elevated mutation rates in the germ line of first- and second-generation offspring of irradiated male mice Ruth Barber, Mark A. Plumb, Emma Boulton, Isabelle Roux, and Yuri E. Dubrova PMCID: PMC124497 Position-effect protection and enhancer blocking by the chicken β-globin insulator are separable activities Félix Recillas-Targa, Michael J. Pikaart, Bonnie Burgess-Beusse, Adam C. Bell, Michael D. Litt, Adam G. West, Miklos Gaszner, and Gary Felsenfeld PMCID: PMC124498 ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos Robert W. Williams and Gerald M. Rubin PMCID: PMC124499 Mnd1p: An evolutionarily conserved protein required for meiotic recombination Jennifer L. Gerton and Joseph L. DeRisi PMCID: PMC124500 Immunology Global changes in gene expression by human polymorphonuclear leukocytes during receptor-mediated phagocytosis: Cell fate is regulated at the level of gene expression Scott D. Kobayashi, Jovanka M. Voyich, Cassandra L. Buhl, Robert M. Stahl, and Frank R. DeLeo PMCID: PMC124501 CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-κB translocation Torsten H. Schroeder, Martin M. Lee, Patrick W. Yacono, Carolyn L. Cannon, A. Alev Gerçeker, David E. Golan, and Gerald B. Pier PMCID: PMC124502 Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120–CD4–CCR5 complexes Maxime Moulard, Sanjay K. Phogat, Yuuei Shu, Aran F. Labrijn, Xiaodong Xiao, James M. Binley, Mei-Yun Zhang, Igor A. Sidorov, Christopher C. Broder, James Robinson, Paul W. H. I. Parren, Dennis R. Burton, and Dimiter S. Dimitrov PMCID: PMC124503 ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction F. Stephen Hodi, Jan C. Schmollinger, Robert J. Soiffer, Ravi Salgia, Thomas Lynch, Jerome Ritz, Edwin P. Alyea, Jihong Yang, Donna Neuberg, Martin Mihm, and Glenn Dranoff PMCID: PMC124504 Siva-1 binds to and inhibits BCL-XL-mediated protection against UV radiation-induced apoptosis Li Xue, Fei Chu, Yuan Cheng, Xiangjie Sun, Alip Borthakur, Manjunath Ramarao, Pramod Pandey, Mei Wu, Stuart F. Schlossman, and Kanteti V. S. Prasad PMCID: PMC124505 Negative selection of thymocytes expressing the D10 TCR Derek B. Sant'Angelo and Charles A. Janeway, Jr. PMCID: PMC124506 Positive selection of self-MHC-reactive T cells by individual peptide–MHC class II complexes Gregory M. Barton, Courtney Beers, Paul deRoos, Susan R. Eastman, Marcela E. Gomez, Katherine A. Forbush, and Alexander Y. Rudensky PMCID: PMC124507 Medical Sciences The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6 Raymond E. Soccio, Rachel M. Adams, Michael J. Romanowski, Ephraim Sehayek, Stephen K. Burley, and Jan L. Breslow PMCID: PMC124508 Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain Michael J. Romanowski, Raymond E. Soccio, Jan L. Breslow, and Stephen K. Burley PMCID: PMC124509 Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression Roberta Bichi, Susan A. Shinton, Eric S. Martin, Anatoliy Koval, George A. Calin, Rossano Cesari, Giandomenico Russo, Richard R. Hardy, and Carlo M. Croce PMCID: PMC124510 Noninvasive imaging of protein–protein interactions in living animals Gary D. Luker, Vijay Sharma, Christina M. Pica, Julie L. Dahlheimer, Wei Li, Joseph Ochesky, Christine E. Ryan, Helen Piwnica-Worms, and David Piwnica-Worms PMCID: PMC124511 Initiating oncogenic event determines gene-expression patterns of human breast cancer models Kartiki V. Desai, Nianqing Xiao, Weili Wang, Lisa Gangi, John Greene, John I. Powell, Robert Dickson, Priscilla Furth, Kent Hunter, Raju Kucherlapati, Richard Simon, Edison T. Liu, and Jeffrey E. Green PMCID: PMC124512 β-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds Sophia S. Cheon, Alexander Y. L. Cheah, Stefanie Turley, Puviindran Nadesan, Raymond Poon, Hans Clevers, and Benjamin A. Alman PMCID: PMC124513 Transmissibility of systemic amyloidosis by a prion-like mechanism Katarzyna Lundmark, Gunilla T. Westermark, Sofia Nyström, Charles L. Murphy, Alan Solomon, and Per Westermark PMCID: PMC124514 Neonatal hepatic steatosis by disruption of the adenosine kinase gene Detlev Boison, Louis Scheurer, Valérie Zumsteg, Thomas Rülicke, Piotr Litynski, Brian Fowler, Sebastian Brandner, and Hanns Mohler PMCID: PMC124515 Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: An alternative mechanism of HBx-related pathogenesis J. Guilherme Tralhao, Jean Roudier, Serban Morosan, Carlo Giannini, Hong Tu, Cyril Goulenok, Françoise Carnot, Flora Zavala, Virginie Joulin, Dina Kremsdorf, and Christian Bréchot PMCID: PMC124516 MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer Tapan K. Bera, Carlo Iavarone, Vasantha Kumar, Sanghyuk Lee, Byungkook Lee, and Ira Pastan PMCID: PMC124517 AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization Cristina Rada, John M. Jarvis, and César Milstein PMCID: PMC124518 Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors Thomas M. J. Niederman, Zoher Ghogawala, Bob S. Carter, Hillary S. Tompkins, Margaret M. Russell, and Richard C. Mulligan PMCID: PMC124519 Persistent HIV-1 infection of natural killer cells in patients receiving highly active antiretroviral therapy Antonio Valentin, Margherita Rosati, Daniel J. Patenaude, Angelos Hatzakis, Leondios G. Kostrikis, Marios Lazanas, Kathleen M. Wyvill, Robert Yarchoan, and George N. Pavlakis PMCID: PMC124520 Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype Annika Jögi, Ingrid Øra, Helén Nilsson, Åsa Lindeheim, Yuichi Makino, Lorenz Poellinger, Håkan Axelson, and Sven Påhlman PMCID: PMC124521 Microbiology Mailborne transmission of anthrax: Modeling and implications Glenn F. Webb and Martin J. Blaser PMCID: PMC124522 Genome-wide screening for trait conferring genes using DNA microarrays R. T. Gill, S. Wildt, Y. T. Yang, S. Ziesman, and G. Stephanopoulos PMCID: PMC124523 Base-specific fragmentation of amplified 16S rRNA genes analyzed by mass spectrometry: A tool for rapid bacterial identification Friedrich von Wintzingerode, Sebastian Böcker, Cord Schlötelburg, Norman H. L. Chiu, Niels Storm, Christian Jurinke, Charles R. Cantor, Ulf B. Göbel, and Dirk van den Boom PMCID: PMC124524 The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen Jeremy Mogridge, Kristina Cunningham, D. Borden Lacy, Michael Mourez, and R. John Collier PMCID: PMC124525 Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen Kristina Cunningham, D. Borden Lacy, Jeremy Mogridge, and R. John Collier PMCID: PMC124526 Rescue of a pathogenic Marek's disease virus with overlapping cosmid DNAs: Use of a pp38 mutant to validate the technology for the study of gene function Sanjay M. Reddy, Blanca Lupiani, Isabel M. Gimeno, Robert F. Silva, Lucy F. Lee, and Richard L. Witter PMCID: PMC124527 From the Cover:
Collaborative signaling by mixed chemoreceptor teams in Escherichia coli Peter Ames, Claudia A. Studdert, Rebecca H. Reiser, and John S. Parkinson PMCID: PMC124528 Identification of a protein secretory pathway for the secretion of heat-labile enterotoxin by an enterotoxigenic strain of Escherichia coli Marija Tauschek, Rebecca J. Gorrell, Richard A. Strugnell, and Roy M. Robins-Browne PMCID: PMC124529 Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa Iain L. Lamont, Paul A. Beare, Urs Ochsner, Adriana I. Vasil, and Michael L. Vasil PMCID: PMC124530 Repression of photosynthesis gene expression by formation of a disulfide bond in CrtJ Shinji Masuda, Chen Dong, Danielle Swem, Aaron T. Setterdahl, David B. Knaff, and Carl E. Bauer PMCID: PMC124531 Neurobiology μ-Opioid receptors and limbic responses to aversive emotional stimuli Israel Liberzon, Jon Kar Zubieta, Lorraine M. Fig, K. Luan Phan, Robert A. Koeppe, and Stephan F. Taylor PMCID: PMC124532 Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor Meiling Lu, Elizabeth A. Grove, and Richard J. Miller PMCID: PMC124533 Differential roles for NSF and GRIP/ABP in AMPA receptor cycling Steven P. Braithwaite, Houhui Xia, and Robert C. Malenka PMCID: PMC124534 The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling Roberta Roncarati, Nenad Šestan, Meir H. Scheinfeld, Bridget E. Berechid, Peter A. Lopez, Olimpia Meucci, Jane C. McGlade, Pasko Rakic, and Luciano D'Adamio PMCID: PMC124535 Centripetal and centrifugal reorganizations of frequency map of auditory cortex in gerbils Masashi Sakai and Nobuo Suga PMCID: PMC124536 Coupling asymmetry of heterotypic connexin 45/ connexin 43-EGFP gap junctions: Properties of fast and slow gating mechanisms Feliksas F. Bukauskas, Angele Bukauskiene, Vytas K. Verselis, and Michael V. L. Bennett PMCID: PMC124537 Growth hormone induces age-dependent alteration in the expression of hippocampal growth hormone receptor and N-methyl-d-aspartate receptor subunits gene transcripts in male rats Madeleine Le Grevès, Pia Steensland, Pierre Le Grevès, and Fred Nyberg PMCID: PMC124538 Dynamin-dependent and dynamin-independent processes contribute to the regulation of single vesicle release kinetics and quantal size Margaret E. Graham, Dermott W. O'Callaghan, Harvey T. McMahon, and Robert D. Burgoyne PMCID: PMC124539 Pharmacology Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2 synthases Olivier Boutaud, David M. Aronoff, Jacob H. Richardson, Lawrence J. Marnett, and John A. Oates PMCID: PMC124540 Anticonvulsant activity of a nonpeptide galanin receptor agonist Külliki Saar, Andrey M. Mazarati, Riina Mahlapuu, Gerd Hallnemo, Ursel Soomets, Kalle Kilk, Sven Hellberg, Margus Pooga, Bo-Ragnar Tolf, Tiejun S. Shi, Tomas Hökfelt, Claude Wasterlain, Tamas Bartfai, and Ülo Langel PMCID: PMC124541 Physiology Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure Rita Holtwick, Michael Gotthardt, Boris Skryabin, Martin Steinmetz, Regine Potthast, Bernd Zetsche, Robert E. Hammer, Joachim Herz, and Michaela Kuhn PMCID: PMC124542 Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes Christos C. Zouboulis, Holger Seltmann, Naoki Hiroi, WenChieh Chen, Maggie Young, Marina Oeff, Werner A. Scherbaum, Constantin E. Orfanos, Samuel M. McCann, and Stefan R. Bornstein PMCID: PMC124543 Aldosterone signaling pathway across the nuclear envelope C. Schäfer, V. Shahin, L. Albermann, M. J. Hug, J. Reinhardt, H. Schillers, S. W. Schneider, and H. Oberleithner PMCID: PMC124544 From the Cover:
Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes Ahmed T. Beggah, Brigitte Escoubet, Stefania Puttini, Stephane Cailmail, Vanessa Delage, Antoine Ouvrard-Pascaud, Brigitte Bocchi, Michel Peuchmaur, Claude Delcayre, Nicolette Farman, and Frederic Jaisser PMCID: PMC124545 Plant Biology The starch-related R1 protein is an α-glucan, water dikinase Gerhard Ritte, James R. Lloyd, Nora Eckermann, Antje Rottmann, Jens Kossmann, and Martin Steup PMCID: PMC124546 Carbocyclic fatty acids in plants: Biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of Sterculia foetida Xiaoming Bao, Sue Katz, Mike Pollard, and John Ohlrogge PMCID: PMC124547 Population Biology Reproductive skew in the polygynandrous acorn woodpecker Joseph Haydock and Walter D. Koenig PMCID: PMC124548 Corrections Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 7184. Published online 2002 April 30. doi: 10.1073/pnas.112148199.PMCID: PMC124427 Corrects: Hongyu Ruan, et al. High-quality life extension by the enzyme peptide methionine sulfoxide reductase. Proc Natl Acad Sci U S A. 2002 March 5; 99(5): 2748–2753. Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 7184. Published online 2002 April 30. doi: 10.1073/pnas.102148799.PMCID: PMC124428 Corrects: Tory M. Hagen, et al. Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci U S A. 2002 February 19; 99(4): 1870–1875. Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 7184. doi: 10.1073/pnas.112140399.PMCID: PMC124429 Corrects: S. I. Shah, et al. Study of Nd3+, Pd2+, Pt4+, and Fe3+ dopant effect on photoreactivity of TiO2 nanoparticles. Proc Natl Acad Sci U S A. 2002 April 30; 99(Suppl 2): 6482–6486. Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 7184. doi: 10.1073/pnas.112148499.PMCID: PMC124430 Corrects: Alexander G. Pletnev, et al. From the Cover:
West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacy. Proc Natl Acad Sci U S A. 2002 March 5; 99(5): 3036–3041. Proc Natl Acad Sci U S A. 2002 May 14; 99(10): 7184. Published online 2002 April 30. doi: 10.1073/pnas.102105799.PMCID: PMC124431 Corrects: Jiankang Liu, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-l-carnitine and/or R-α-lipoic acid. Proc Natl Acad Sci U S A. 2002 February 19; 99(4): 2356–2361. |
