| | This journal provides immediate access to some articles. Editorial PNAS gives free online access to developing countries Nicholas R. Cozzarelli, Kenneth R. Fulton, and Diane M. Sullenberger PMCID: PMC122844 Commentaries Antibiotics in agriculture: When is it time to close the barn door? Marc Lipsitch, Randall S. Singer, and Bruce R. Levin PMCID: PMC122845 Unraveling the genetics and mechanisms of cardiac arrhythmia Denis Noble PMCID: PMC122846 Disentangling the MYC web David Levens PMCID: PMC122847 Brain-directed gene therapy for lysosomal storage disease: Going well beyond the blood– brain barrier William S. Sly and Carole Vogler PMCID: PMC122848 Finding the crosswalks on DNA Clifford F. Weil PMCID: PMC122849 Physical Sciences Applied Mathematics A simple model of global cascades on random networks Duncan J. Watts PMCID: PMC122850 A model of a turbulent boundary layer with a nonzero pressure gradient G. I. Barenblatt, A. J. Chorin, and V. M. Prostokishin PMCID: PMC122851 Applied Physical Sciences From the Cover:
Simulating materials failure by using up to one billion atoms and the world's fastest computer: Brittle fracture Farid F. Abraham, Robert Walkup, Huajian Gao, Mark Duchaineau, Tomas Diaz De La Rubia, and Mark Seager PMCID: PMC122852 Simulating materials failure by using up to one billion atoms and the world's fastest computer: Work-hardening Farid F. Abraham, Robert Walkup, Huajian Gao, Mark Duchaineau, Tomas Diaz De La Rubia, and Mark Seager PMCID: PMC122853 Adaptive aberration correction in a confocal microscope Martin J. Booth, Mark A. A. Neil, Rimas Juškaitis, and Tony Wilson PMCID: PMC122854 Chemistry The concerted mechanism of photo-induced biprotonic transfer in 7-azaindole dimers: Structure, quantum-theoretical analysis, and simultaneity principles Javier Catalán, Pilar Pérez, Juan Carlos del Valle, J. L. G. de Paz, and Michael Kasha PMCID: PMC122855 The concerted mechanism of photo-induced biprotonic transfer in 7-azaindole dimers: A model for the secondary evolution of the classic C2h dimer and comparison of four mechanisms Javier Catalán, Pilar Pérez, Juan Carlos del Valle, J. L. G. de Paz, and Michael Kasha PMCID: PMC122856 Organic semiconductors: A theoretical characterization of the basic parameters governing charge transport J. L. Brédas, J. P. Calbert, D. A. da Silva Filho, and J. Cornil PMCID: PMC122857 Chiral protein scissors: High enantiomeric selectivity for binding and its effect on protein photocleavage efficiency and specificity Challa V. Kumar, Apinya Buranaprapuk, Ho C. Sze, Steffen Jockusch, and Nicholas J. Turro PMCID: PMC122858 Determination of causal connectivities of species in reaction networks William Vance, Adam Arkin, and John Ross PMCID: PMC122859 Physics Allometric scaling and maximum efficiency in physiological eigen time Bjarne Andresen, J. S. Shiner, and Dominik E. Uehlinger PMCID: PMC122860 Curvature of co-links uncovers hidden thematic layers in the World Wide Web Jean-Pierre Eckmann and Elisha Moses PMCID: PMC122861 Biological Sciences Agricultural Sciences Loss of the membrane anchor of the target receptor is a mechanism of bioinsecticide resistance Isabelle Darboux, Yannick Pauchet, Claude Castella, Maria Helena Silva-Filha, Christina Nielsen-LeRoux, Jean-François Charles, and David Pauron PMCID: PMC122862 Genetic analysis of traditional and evolved Basmati and non-Basmati rice varieties by using fluorescence-based ISSR-PCR and SSR markers J. Nagaraju, M. Kathirvel, R. Ramesh Kumar, E. A. Siddiq, and Seyed E. Hasnain PMCID: PMC122863 Biochemistry Interactions that determine the assembly of a retinoid X receptor/corepressor complex Jagadish C. Ghosh, Xiaofang Yang, Aihua Zhang, Millard H. Lambert, Hui Li, H. Eric Xu, and J. Don Chen PMCID: PMC122864 Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions Karen M. Vasquez, Jesper Christensen, Lei Li, Rick A. Finch, and Peter M. Glazer PMCID: PMC122865 Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans Jennifer L. Watts and John Browse PMCID: PMC122866 Precision and functional specificity in mRNA decay Yulei Wang, Chih Long Liu, John D. Storey, Robert J. Tibshirani, Daniel Herschlag, and Patrick O. Brown PMCID: PMC122867 A family of RRM-type RNA-binding proteins specific to plant mitochondria Matthieu Vermel, Benoit Guermann, Ludovic Delage, Jean-Michel Grienenberger, Laurence Maréchal-Drouard, and José M. Gualberto PMCID: PMC122868 The crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-d-arabinonohydroxamic acid Diana Arsenieva, Renaud Hardré, Laurent Salmon, and Constance J. Jeffery PMCID: PMC122869 Solution structures of the cytoplasmic tail complex from platelet integrin αIIb- and β3-subunits Aalim M. Weljie, Peter M. Hwang, and Hans J. Vogel PMCID: PMC122870 Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei Janine R. Roper, Maria Lucia S. Güther, Kenneth G. Milne, and Michael A. J. Ferguson PMCID: PMC122871 The identification of functional modules from the genomic association of genes Berend Snel, Peer Bork, and Martijn A. Huynen PMCID: PMC122872 Interrogating protein interaction networks through structural biology Patrick Aloy and Robert B. Russell PMCID: PMC122873 Truncated hemoglobin HbN protects Mycobacterium bovis from nitric oxide Hugues Ouellet, Yannick Ouellet, Christian Richard, Marie Labarre, Beatrice Wittenberg, Jonathan Wittenberg, and Michel Guertin PMCID: PMC122874 The crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activity Atsushi Yamagata, Yoshimitsu Kakuta, Ryoji Masui, and Keiichi Fukuyama PMCID: PMC122875 Catalysis of S-nitrosothiols formation by serum albumin: The mechanism and implication in vascular control Olga Rafikova, Ruslan Rafikov, and Evgeny Nudler PMCID: PMC122876 Isoform-specific interaction of HP1 with human TAFII130 Milo F. Vassallo and Naoko Tanese PMCID: PMC122877 A chloroplast-resident DNA methyltransferase is responsible for hypermethylation of chloroplast genes in Chlamydomonas maternal gametes Rie Nishiyama, Mikako Ito, Yube Yamaguchi, Nozomu Koizumi, and Hiroshi Sano PMCID: PMC122878 Calreticulin recognizes misfolded HLA-A2 heavy chains Laura Mancino, Syed Monem Rizvi, Philip Edward Lapinski, and Malini Raghavan PMCID: PMC122879 Antioxidant-induced changes in oxidized DNA Donald C. Malins, Karl Erik Hellström, Katie M. Anderson, Paul M. Johnson, and Mark A. Vinson PMCID: PMC122880 Direct mass spectrometric analysis of intact proteins of the yeast large ribosomal subunit using capillary LC/FTICR Sang-Won Lee, Scott J. Berger, Suzana Martinović, Ljiljana Paša-Tolić, Gordon A. Anderson, Yufeng Shen, Rui Zhao, and Richard D. Smith PMCID: PMC122881 Cys-328 of IscS and Cys-63 of IscU are the sites of disulfide bridge formation in a covalently bound IscS/IscU complex: Implications for the mechanism of iron-sulfur cluster assembly Shin-ichiro Kato, Hisaaki Mihara, Tatsuo Kurihara, Yasuhiro Takahashi, Umechiyo Tokumoto, Tohru Yoshimura, and Nobuyoshi Esaki PMCID: PMC122882 Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids Vadim V. Demidov, Ekaterina Protozanova, Konstantin I. Izvolsky, Christopher Price, Peter E. Nielsen, and Maxim D. Frank-Kamenetskii PMCID: PMC122883 Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein Miwako Kato Homma, Dongxia Li, Edwin G. Krebs, Yasuhito Yuasa, and Yoshimi Homma PMCID: PMC122884 Modulation of tRNAAla identity by inorganic pyrophosphatase Alexey D. Wolfson and Olke C. Uhlenbeck PMCID: PMC122885 Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ Jayasree S. Nair, Christopher J. DaFonseca, Agneta Tjernberg, Wei Sun, James E. Darnell, Jr., Brian T. Chait, and J. Jillian Zhang PMCID: PMC122886 Biophysics Kinesin–microtubule binding depends on both nucleotide state and loading direction Sotaro Uemura, Kenji Kawaguchi, Junichiro Yajima, Masaki Edamatsu, Yoko Yano Toyoshima, and Shin'ichi Ishiwata PMCID: PMC122887 Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography Tetsuji Okada, Yoshinori Fujiyoshi, Maria Silow, Javier Navarro, Ehud M. Landau, and Yoshinori Shichida PMCID: PMC122888 Mechanisms of noise-resistance in genetic oscillators José M. G. Vilar, Hao Yuan Kueh, Naama Barkai, and Stanislas Leibler PMCID: PMC122889 Ab initio protein structure prediction on a genomic scale: Application to the Mycoplasma genitalium genome Daisuke Kihara, Yang Zhang, Hui Lu, Andrzej Kolinski, and Jeffrey Skolnick PMCID: PMC122890 Conformational pathways in the gating of Escherichia coli mechanosensitive channel Yifei Kong, Yufeng Shen, Tiffany E. Warth, and Jianpeng Ma PMCID: PMC122891 Observation by fluorescence microscopy of transcription on single combed DNA Z. Gueroui, C. Place, E. Freyssingeas, and B. Berge PMCID: PMC122892 Holding two heads together: Stability of the myosin II rod measured by resonance energy transfer between the heads Tania Chakrabarty, Ming Xiao, Roger Cooke, and Paul R. Selvin PMCID: PMC122893 An alternative carotenoid-to-bacteriochlorophyll energy transfer pathway in photosynthetic light harvesting Emmanouil Papagiannakis, John T. M. Kennis, Ivo H. M. van Stokkum, Richard J. Cogdell, and Rienk van Grondelle PMCID: PMC122894 Cell Biology A dynamic shift of VEGF isoforms with a transient and selective progesterone-induced expression of VEGF189 regulates angiogenesis and vascular permeability in human uterus Magali Ancelin, Hélène Buteau-Lozano, Geri Meduri, Mary Osborne-Pellegrin, Sylvie Sordello, Jean Plouët, and Martine Perrot-Applanat PMCID: PMC122895 Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells Jian-Kang Chen, Jorge Capdevila, and Raymond C. Harris PMCID: PMC122896 Estimates of lateral and longitudinal bond energies within the microtubule lattice Vincent VanBuren, David J. Odde, and Lynne Cassimeris PMCID: PMC122897 The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins James E. Egan, Amy B. Hall, Bogdan A. Yatsula, and Dafna Bar-Sagi PMCID: PMC122898 RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells Jenn-Yah Yu, Stacy L. DeRuiter, and David L. Turner PMCID: PMC122899 Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9 Zijuan Liu, Jian Shen, Jennifer M. Carbrey, Rita Mukhopadhyay, Peter Agre, and Barry P. Rosen PMCID: PMC122900 Developmental Biology From intestine to muscle: Nuclear reprogramming through defective cloned embryos J. A. Byrne, S. Simonsson, and J. B. Gurdon PMCID: PMC122901 The LEF1/β-catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation Baoan Li, Douglas R. Mackay, Qian Dai, Tony W. H. Li, Mahalakshmi Nair, Magid Fallahi, Christopher P. Schonbaum, Judith Fantes, Anthony P. Mahowald, Marian L. Waterman, Elaine Fuchs, and Xing Dai PMCID: PMC122902 Ecology Climate change hastens population extinctions John F. McLaughlin, Jessica J. Hellmann, Carol L. Boggs, and Paul R. Ehrlich PMCID: PMC122903 Evolution Evolution of supercolonies: The Argentine ants of southern Europe Tatiana Giraud, Jes S. Pedersen, and Laurent Keller PMCID: PMC122904 A single domestication for maize shown by multilocus microsatellite genotyping Yoshihiro Matsuoka, Yves Vigouroux, Major M. Goodman, Jesus Sanchez G., Edward Buckler, and John Doebley PMCID: PMC122905 Evolutionary recruitment of a flavin-dependent monooxygenase for the detoxification of host plant-acquired pyrrolizidine alkaloids in the alkaloid-defended arctiid moth Tyria jacobaeae Claudia Naumann, Thomas Hartmann, and Dietrich Ober PMCID: PMC122906 Evolution of the RNA polymerase II C-terminal domain John W. Stiller and Benjamin D. Hall PMCID: PMC122907 The global phylogeny of glycolytic enzymes B. Canback, S. G. E. Andersson, and C. G. Kurland PMCID: PMC122908 Mutator clones of Neisseria meningitidis in epidemic serogroup A disease Anthony R. Richardson, Zhong Yu, Tanja Popovic, and Igor Stojiljkovic PMCID: PMC122909 Genetic basis for queen–worker dimorphism in a social insect Veronica P. Volny and Deborah M. Gordon PMCID: PMC122910 Reconciling paleodistribution models and comparative phylogeography in the Wet Tropics rainforest land snail Gnarosophia bellendenkerensis (Brazier 1875) Andrew Hugall, Craig Moritz, Adnan Moussalli, and John Stanisic PMCID: PMC122911 Intron evolution as a population-genetic process Michael Lynch PMCID: PMC122912 Dental microstructure and life history in subfossil Malagasy lemurs Gary T. Schwartz, Karen E. Samonds, Laurie R. Godfrey, William L. Jungers, and Elwyn L. Simons PMCID: PMC122913 Genetics A mutation that prevents paramutation in maize also reverses Mutator transposon methylation and silencing Damon Lisch, Charles C. Carey, Jane E. Dorweiler, and Vicki L. Chandler PMCID: PMC122914 Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies Ting Xi Liu, Yi Zhou, John P. Kanki, Min Deng, Jennifer Rhodes, Hong Wei Yang, Xiao Ming Sheng, Leonard I. Zon, and A. Thomas Look PMCID: PMC122915 Regulation of transcription by H1 phosphorylation in Tetrahymena is position independent and requires clustered sites Yali Dou and Martin A. Gorovsky PMCID: PMC122916 Utility and distribution of conserved noncoding sequences in the grasses Nicholas J. Kaplinsky, David M. Braun, Jon Penterman, Stephen A. Goff, and Michael Freeling PMCID: PMC122917 Oligo(dT) primer generates a high frequency of truncated cDNAs through internal poly(A) priming during reverse transcription Douglas Kyung Nam, Sanggyu Lee, Guolin Zhou, Xiaohong Cao, Clarence Wang, Terry Clark, Jianjun Chen, Janet D. Rowley, and San Ming Wang PMCID: PMC122918 From the Cover:
Molecular characterization of meiotic recombination across the 140-kb multigenic a1-sh2 interval of maize Hong Yao, Qing Zhou, Jin Li, Heather Smith, Marna Yandeau, Basil J. Nikolau, and Patrick S. Schnable PMCID: PMC122919 Reverse engineering gene networks using singular value decomposition and robust regression M. K. Stephen Yeung, Jesper Tegnér, and James J. Collins PMCID: PMC122920 Asymmetrical flagellar rotation in Borrelia burgdorferi nonchemotactic mutants Chunhao Li, Richard G. Bakker, Md. Abdul Motaleb, Marina L. Sartakova, Felipe C. Cabello, and Nyles W. Charon PMCID: PMC122921 Immunology Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs Geetha Chalasani, Zhenhua Dai, Bogumila T. Konieczny, Fady K. Baddoura, and Fadi G. Lakkis PMCID: PMC122922 MIP-1α, MIP-1β, RANTES, and ATAC/lymphotactin function together with IFN-γ as type 1 cytokines Brigitte G. Dorner, Alexander Scheffold, Michael S. Rolph, Martin B. Hüser, Stefan H. E. Kaufmann, Andreas Radbruch, Inge E. A. Flesch, and Richard A. Kroczek PMCID: PMC122923 Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells Nobuki Hayashi, Dacai Liu, Booki Min, Shlomo Z. Ben-Sasson, and William E. Paul PMCID: PMC122924 IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells Kebin Liu, Marta Catalfamo, Yu Li, Pierre A. Henkart, and Nan-ping Weng PMCID: PMC122925 ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells Saman Khayyamian, Andreas Hutloff, Kerstin Büchner, Michael Gräfe, Volker Henn, Richard A. Kroczek, and Hans W. Mages PMCID: PMC122926 Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells Lili Yang, Xiao-Feng Qin, David Baltimore, and Luk Van Parijs PMCID: PMC122927 Medical Sciences From the Cover:
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a G. Alex Papadatos, Polly M. R. Wallerstein, Catherine E. G. Head, Rosemary Ratcliff, Peter A. Brady, Klaus Benndorf, Richard C. Saumarez, Ann E. O. Trezise, Christopher L.-H. Huang, Jamie I. Vandenberg, William H. Colledge, and Andrew A. Grace PMCID: PMC122928 From the Cover:
Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors Andrew I. Brooks, Colleen S. Stein, Stephanie M. Hughes, Jason Heth, Paul M. McCray, Jr., Sybille L. Sauter, Julie C. Johnston, Deborah A. Cory-Slechta, Howard J. Federoff, and Beverly L. Davidson PMCID: PMC122929 Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure Bernhard H. F. Weber, Heinrich Schrewe, Laurie L. Molday, Andrea Gehrig, Karen L. White, Mathias W. Seeliger, Gesine B. Jaissle, Christoph Friedburg, Ernst Tamm, and Robert S. Molday PMCID: PMC122930 Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in mice Johannes F. M. Pruijt, Perry Verzaal, Ronald van Os, Evert-Jan F. M. de Kruijf, Marianke L. J. van Schie, Alberto Mantovani, Annunciata Vecchi, Ivan J. D. Lindley, Roel Willemze, Sofie Starckx, Ghislain Opdenakker, and Willem E. Fibbe PMCID: PMC122931 Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L Jörg Stypmann, Kerstin Gläser, Wera Roth, Desmond J. Tobin, Ivonne Petermann, Rainer Matthias, Gerold Mönnig, Wilhelm Haverkamp, Günter Breithardt, Wolfgang Schmahl, Christoph Peters, and Thomas Reinheckel PMCID: PMC122932 Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22 Ingrid Zwaenepoel, Mirna Mustapha, Michel Leibovici, Elisabeth Verpy, Richard Goodyear, Xue Zhong Liu, Sylvie Nouaille, Walter E. Nance, Moien Kanaan, Karen B. Avraham, Fredj Tekaia, Jacques Loiselet, Marc Lathrop, Guy Richardson, and Christine Petit PMCID: PMC122933 Differential regulation of the human and murine CD34 genes in hematopoietic stem cells Yutaka Okuno, Hiromi Iwasaki, Claudia S. Huettner, Hanna S. Radomska, David A. Gonzalez, Daniel G. Tenen, and Koichi Akashi PMCID: PMC122934 Functional consequences of caspase activation in cardiac myocytes Catherine Communal, Marius Sumandea, Pieter de Tombe, Jagat Narula, R. John Solaro, and Roger J. Hajjar PMCID: PMC122935 bcl-2 overexpression promotes myocyte proliferation Federica Limana, Konrad Urbanek, Stefano Chimenti, Federico Quaini, Annarosa Leri, Jan Kajstura, Bernardo Nadal-Ginard, Seigo Izumo, and Piero Anversa PMCID: PMC122936 Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus Joshua B. Plotkin, Jonathan Dushoff, and Simon A. Levin PMCID: PMC122937 Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model Xu Song, Baiyang Wang, Michael Bromberg, Zhiwei Hu, William Konigsberg, and Alan Garen PMCID: PMC122938 From the Cover:
Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes Antje Menssen and Heiko Hermeking PMCID: PMC122939 Genetic alterations of IL-1 receptor antagonist in mice affect plasma cholesterol level and foam cell lesion size Cecilia M. Devlin, George Kuriakose, Emmet Hirsch, and Ira Tabas PMCID: PMC122940 Lysosomal destabilization in p53-induced apoptosis Xi-Ming Yuan, Wei Li, Helge Dalen, Joseph Lotem, Rachel Kama, Leo Sachs, and Ulf T. Brunk PMCID: PMC122941 Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans Fengrong Zuo, Naftali Kaminski, Elsie Eugui, John Allard, Zohar Yakhini, Amir Ben-Dor, Lance Lollini, David Morris, Yong Kim, Barbara DeLustro, Dean Sheppard, Annie Pardo, Moises Selman, and Renu A. Heller PMCID: PMC122942 Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues Miranda Van Eck, I. Sophie T. Bos, Wolfgang E. Kaminski, Evelyn Orsó, Gregor Rothe, Jaap Twisk, Alfred Böttcher, Edwin S. Van Amersfoort, Trudy A. Christiansen-Weber, Wai-Ping Fung-Leung, Theo J. C. Van Berkel, and Gerd Schmitz PMCID: PMC122943 Microbiology Genetic complementation in apicomplexan parasites Boris Striepen, Michael W. White, Catherine Li, Michael N. Guerini, S.-Banoo Malik, John M. Logsdon, Jr., Chang Liu, and Mitchell S. Abrahamsen PMCID: PMC122944 Pregnancy status and fetal prion genetics determine PrPSc accumulation in placentomes of scrapie-infected sheep Wenbin Tuo, Katherine I. O'Rourke, Dongyue Zhuang, William P. Cheevers, Terry R. Spraker, and Donald P. Knowles PMCID: PMC122945 YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site Nienke Buddelmeijer, Nicholas Judson, Dana Boyd, John J. Mekalanos, and Jonathan Beckwith PMCID: PMC122946 IRF-3-dependent, NFκB- and JNK-independent activation of the 561 and IFN-β genes in response to double-stranded RNA Kristi L. Peters, Heather L. Smith, George R. Stark, and Ganes C. Sen PMCID: PMC122947 Neurobiology Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa James W. Kijas, Artur V. Cideciyan, Tomas S. Aleman, Michael J. Pianta, Susan E. Pearce-Kelling, Brian J. Miller, Samuel G. Jacobson, Gustavo D. Aguirre, and Gregory M. Acland PMCID: PMC122948 Inclusion body myositis-like phenotype induced by transgenic overexpression of βAPP in skeletal muscle Michael C. Sugarman, Tritia R. Yamasaki, Salvatore Oddo, Julio C. Echegoyen, M. Paul Murphy, Todd E. Golde, Mehrdad Jannatipour, Malcolm A. Leissring, and Frank M. LaFerla PMCID: PMC122949 General and variable features of varicosity spacing along unmyelinated axons in the hippocampus and cerebellum Gordon M. G. Shepherd, Morten Raastad, and Per Andersen PMCID: PMC122950 Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1 Hannes E. Bülow, Katherine L. Berry, Liat H. Topper, Elior Peles, and Oliver Hobert PMCID: PMC122951 Plasticity of orientation preference maps in the visual cortex of adult cats Ben Godde, Ralph Leonhardt, Sven M. Cords, and Hubert R. Dinse PMCID: PMC122952 Sustained stimulation shifts the mechanism of endocytosis from dynamin-1-dependent rapid endocytosis to clathrin- and dynamin-2-mediated slow endocytosis in chromaffin cells Cristina R. Artalejo, Abdeladim Elhamdani, and H. Clive Palfrey PMCID: PMC122953 Tau is essential to β-amyloid-induced neurotoxicity Mark Rapoport, Hana N. Dawson, Lester I. Binder, Michael P. Vitek, and Adriana Ferreira PMCID: PMC122954 Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders Guy Griebel, Jacques Simiand, Claudine Serradeil-Le Gal, Jean Wagnon, Marc Pascal, Bernard Scatton, Jean-Pierre Maffrand, and Philippe Soubrié PMCID: PMC122955 Altered sexual and social behaviors in trp2 mutant mice Bradley G. Leypold, C. Ron Yu, Trese Leinders-Zufall, Michelle M. Kim, Frank Zufall, and Richard Axel PMCID: PMC122956 Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers Michael J. Bannon, Barb Pruetz, Amy B. Manning-Bog, Christopher J. Whitty, Sharon K. Michelhaugh, Paola Sacchetti, James G. Granneman, Deborah C. Mash, and Carl J. Schmidt PMCID: PMC122957 Neurotrophin secretion from hippocampal neurons evoked by long-term-potentiation-inducing electrical stimulation patterns Annette Gärtner and Volker Staiger PMCID: PMC122958 Pharmacology Catalysis of S-nitrosothiols formation by serum albumin: The mechanism and implication in vascular control Olga Rafikova, Ruslan Rafikov, and Evgeny Nudler PMCID: PMC122876 cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electrotonic conduction via gap junctions Tudor M. Griffith, Andrew T. Chaytor, Hannah J. Taylor, Beverley D. Giddings, and David H. Edwards PMCID: PMC122959 Physiology Allometric scaling and maximum efficiency in physiological eigen time Bjarne Andresen, J. S. Shiner, and Dominik E. Uehlinger PMCID: PMC122860 Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death David Vaudry, Cécile Rousselle, Magali Basille, Anthony Falluel-Morel, Tommy F. Pamantung, Marc Fontaine, Alain Fournier, Hubert Vaudry, and Bruno J. Gonzalez PMCID: PMC122960 Visualization of Ca2+ entry through single stretch-activated cation channels Hui Zou, Lawrence M. Lifshitz, Richard A. Tuft, Kevin E. Fogarty, and Joshua J. Singer PMCID: PMC122961 Plant Biology Ectopic D-type cyclin expression induces not only DNA replication but also cell division in Arabidopsis trichomes Arp Schnittger, Ulrike Schöbinger, Daniel Bouyer, Christina Weinl, York-Dieter Stierhof, and Martin Hülskamp PMCID: PMC122962 Distinct roles for jasmonate synthesis and action in the systemic wound response of tomato Lei Li, Chuanyou Li, Gyu In Lee, and Gregg A. Howe PMCID: PMC122963 Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene Benoît Menand, Thierry Desnos, Laurent Nussaume, Frédéric Berger, David Bouchez, Christian Meyer, and Christophe Robaglia PMCID: PMC122964 Glycine residues in potassium channel-like selectivity filters determine potassium selectivity in four-loop-per-subunit HKT transporters from plants Pascal Mäser, Yoshihiro Hosoo, Shinobu Goshima, Tomoaki Horie, Brendan Eckelman, Katsuyuki Yamada, Kazuya Yoshida, Evert P. Bakker, Atsuhiko Shinmyo, Shigetoshi Oiki, Julian I. Schroeder, and Nobuyuki Uozumi PMCID: PMC122965 Population Biology Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria David L. Smith, Anthony D. Harris, Judith A. Johnson, Ellen K. Silbergeld, and J. Glenn Morris, Jr. PMCID: PMC122966 Psychology Interactions between thalamic and cortical rhythms during semantic memory recall in human Scott D. Slotnick, Lauren R. Moo, Michael A. Kraut, Ronald P. Lesser, and John Hart, Jr. PMCID: PMC122967 Social Sciences Anthropology Evidence for interpersonal violence in the St. Césaire Neanderthal Christoph P. E. Zollikofer, Marcia S. Ponce de León, Bernard Vandermeersch, and François Lévêque PMCID: PMC122968 Correction Proc Natl Acad Sci U S A. 2002 April 30; 99(9): 6449. Published online 2002 April 9. doi: 10.1073/pnas.092105699.PMCID: PMC122843 Corrects: Jakob B. Sørensen, et al. The SNARE protein SNAP-25 is linked to fast calcium triggering of exocytosis. Proc Natl Acad Sci U S A. 2002 February 5; 99(3): 1627–1632. |
