| | This journal provides immediate access to some articles. Commentaries Recognizing the D-loop of transfer RNAs Tamara L. Hendrickson PMCID: PMC61062 Glucose and cAMP: Adversaries in the regulation of hepatic gene expression Howard C. Towle PMCID: PMC61063 Molecular scaffolds for chemical wizardry: Learning nature's rules for terpene cyclases Bryan Greenhagen and Joseph Chappell PMCID: PMC61064 The many dimensions of cAMP signaling James H. Schwartz PMCID: PMC61065 A fossil record of zidovudine resistance in transmitted isolates of HIV-1 Daniel R. Kuritzkes PMCID: PMC61066 Structural genomics: An approach to the protein folding problem Gaetano T. Montelione PMCID: PMC61067 Physical Sciences Geology Magnetite morphology and life on Mars Peter R. Buseck, Rafal E. Dunin-Borkowski, Bertrand Devouard, Richard B. Frankel, Martha R. McCartney, Paul A. Midgley, Mihály Pósfai, and Matthew Weyland PMCID: PMC61068 Physics INAUGURAL ARTICLE by a Recently Elected Academy Member: Singlet exciton binding energy in poly(phenylene vinylene) D. Moses, J. Wang, A. J. Heeger, N. Kirova, and S. Brazovski PMCID: PMC61069 Biological Sciences Applied Biological Sciences INAUGURAL ARTICLE by a Recently Elected Academy Member: Maintenance of genetic integrity in frozen and freeze-dried mouse spermatozoa Hirokazu Kusakabe, Monika A. Szczygiel, David G. Whittingham, and Ryuzo Yanagimachi PMCID: PMC61070 INAUGURAL ARTICLE by a Recently Elected Academy Member: Modulation of intestinal gene expression by dietary zinc status: Effectiveness of cDNA arrays for expression profiling of a single nutrient deficiency Raymond K. Blanchard, J. Bernadette Moore, Calvert L. Green, and Robert J. Cousins PMCID: PMC61071 Biochemistry Synthesis of an organoinsulin molecule that can be activated by antibody catalysis Dorothy S. Worrall, Jonathan E. McDunn, Benjamin List, Donna Reichart, Andrea Hevener, Thomas Gustafson, Carlos F. Barbas, III, Richard A. Lerner, and Jerrold M. Olefsky PMCID: PMC61072 The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems Norman Kairies, Hans-Georg Beisel, Pablo Fuentes-Prior, Ryoko Tsuda, Tatsushi Muta, Sadaaki Iwanaga, Wolfram Bode, Robert Huber, and Shun-ichiro Kawabata PMCID: PMC61073 Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat Samuel M. Young, Jr. and Richard Jude Samulski PMCID: PMC61074 Profiling the global tyrosine phosphorylation state by Src homology 2 domain binding Peter Nollau and Bruce J. Mayer PMCID: PMC61075 From the Cover:
Structural and mutational studies of the recognition of the arginine tRNA-specific major identity element, A20, by arginyl-tRNA synthetase Atsushi Shimada, Osamu Nureki, Mie Goto, Seizo Takahashi, and Shigeyuki Yokoyama PMCID: PMC61076 From the Cover:
Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascade Michael J. Rynkiewicz, David E. Cane, and David W. Christianson PMCID: PMC61077 An in vivo ESR spin-trapping study: Free radical generation in rats from formate intoxication— role of the Fenton reaction Anna E. Dikalova, Maria B. Kadiiska, and Ronald P. Mason PMCID: PMC61078 Alzheimer's β-secretase, β-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase Shinobu Kitazume, Yuriko Tachida, Ritsuko Oka, Keiro Shirotani, Takaomi C. Saido, and Yasuhiro Hashimoto PMCID: PMC61079 Crystal structure of thermostable DNA photolyase: Pyrimidine-dimer recognition mechanism Hirofumi Komori, Ryoji Masui, Seiki Kuramitsu, Shigeyuki Yokoyama, Takehiko Shibata, Yorinao Inoue, and Kunio Miki PMCID: PMC61080 Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice Praveena Gupta, Abigail A. Soyombo, Armita Atashband, Krystyna E. Wisniewski, John M. Shelton, James A. Richardson, Robert E. Hammer, and Sandra L. Hofmann PMCID: PMC61081 Parathyroid hormone regulates 25-hydroxyvitamin D3-24-hydroxylase mRNA by altering its stability Claudia Zierold, Jamie A. Mings, and Hector F. DeLuca PMCID: PMC61082 Bacillus subtilis arsenate reductase is structurally and functionally similar to low molecular weight protein tyrosine phosphatases Matthew S. Bennett, Zhi Guan, Martin Laurberg, and Xiao-Dong Su PMCID: PMC61083 Rational design of coagulation factor VIIa variants with substantially increased intrinsic activity Egon Persson, Marianne Kjalke, and Ole H. Olsen PMCID: PMC61084 The Schizosaccharomyces pombe origin recognition complex interacts with multiple AT-rich regions of the replication origin DNA by means of the AT-hook domains of the spOrc4 protein Joon-Kyu Lee, Kyeong-Yeop Moon, Yun Jiang, and Jerard Hurwitz PMCID: PMC61085 Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase Stefan Jennewein, Christopher D. Rithner, Robert M. Williams, and Rodney B. Croteau PMCID: PMC61086 JAC, a direct target of oncogenic transcription factor Jun, is involved in cell transformation and tumorigenesis Markus Hartl, Fritz Reiter, Andreas G. Bader, Marc Castellazzi, and Klaus Bister PMCID: PMC61087 Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene Jian Yang, Joseph L. Goldstein, Robert E. Hammer, Young-Ah Moon, Michael S. Brown, and Jay D. Horton PMCID: PMC61088 Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1 Yu Shen, Ralf Luche, Bo Wei, Marcia L. Gordon, Curtis D. Diltz, and Nicholas K. Tonks PMCID: PMC61089 Mechanism of ATP-driven electron transfer catalyzed by the benzene ring-reducing enzyme benzoyl- CoA reductase Mihaela Unciuleac and Matthias Boll PMCID: PMC61090 Ryanodine sensitizes the cardiac Ca2+ release channel (ryanodine receptor isoform 2) to Ca2+ activation and dissociates as the channel is closed by Ca2+ depletion Guo Guang Du, Xinghua Guo, Vijay K. Khanna, and David H. MacLennan PMCID: PMC61091 Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription Renate Voit and Ingrid Grummt PMCID: PMC61092 Responses of python gastrointestinal regulatory peptides to feeding Stephen M. Secor, Drew Fehsenfeld, Jared Diamond, and Thomas E. Adrian PMCID: PMC61093 Biophysics High refractive index substrates for fluorescence microscopy of biological interfaces with high z contrast Caroline M. Ajo-Franklin, Lance Kam, and Steven G. Boxer PMCID: PMC61094 Pause and rotation of F1-ATPase during catalysis Yoko Hirono-Hara, Hiroyuki Noji, Masaya Nishiura, Eiro Muneyuki, Kiyotaka Y. Hara, Ryohei Yasuda, Kazuhiko Kinosita, Jr., and Masasuke Yoshida PMCID: PMC61095 Myosin VI is a processive motor with a large step size Ronald S. Rock, Sarah E. Rice, Amber L. Wells, Thomas J. Purcell, James A. Spudich, and H. Lee Sweeney PMCID: PMC61096 Surface organization and nanopatterning of collagen by dip-pen nanolithography Donna L. Wilson, Raquel Martin, Seunghun Hong, Mark Cronin-Golomb, Chad A. Mirkin, and David L. Kaplan PMCID: PMC61097 X-ray analysis of an RNA tetraplex (UGGGGU)4 with divalent Sr2+ ions at subatomic resolution (0.61 Å) Junpeng Deng, Yong Xiong, and Muttaiya Sundaralingam PMCID: PMC61098 DNA packaging and ejection forces in bacteriophage James Kindt, Shelly Tzlil, Avinoam Ben-Shaul, and William M. Gelbart PMCID: PMC61099 Cell Biology Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle Michele H. Jones, Xiangwei He, Thomas H. Giddings, and Mark Winey PMCID: PMC61100 SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase Brydon L. Bennett, Dennis T. Sasaki, Brion W. Murray, Eoin C. O'Leary, Steve T. Sakata, Weiming Xu, Jim C. Leisten, Aparna Motiwala, Steve Pierce, Yoshitaka Satoh, Shripad S. Bhagwat, Anthony M. Manning, and David W. Anderson PMCID: PMC61101 A molecular profile of the mouse gastric parietal cell with and without exposure to Helicobacter pylori Jason C. Mills, Andrew J. Syder, Chieu V. Hong, Janaki L. Guruge, Farhang Raaii, and Jeffrey I. Gordon PMCID: PMC61102 Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis Aixiang Jiang, Kaisa Lehti, Xing Wang, Stephen J. Weiss, Jorma Keski-Oja, and Duanqing Pei PMCID: PMC61103 Mammalian myotube dedifferentiation induced by newt regeneration extract Christopher J. McGann, Shannon J. Odelberg, and Mark T. Keating PMCID: PMC61104 Surface structure of the COPII-coated vesicle Ken Matsuoka, Randy Schekman, Lelio Orci, and John E. Heuser PMCID: PMC61105 Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein Takumi Kawaguchi, Makoto Takenoshita, Tsutomu Kabashima, and Kosaku Uyeda PMCID: PMC61106 Fringe modulation of Jagged1-induced Notch signaling requires the action of β4galactosyltransferase-1 Jihua Chen, Daniel J. Moloney, and Pamela Stanley PMCID: PMC61107 Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells Frédéric Sierro, Bertrand Dubois, Alix Coste, Dominique Kaiserlian, Jean-Pierre Kraehenbuhl, and Jean-Claude Sirard PMCID: PMC61108 Evidence that androgens are the primary steroids produced by Xenopus laevis ovaries and may signal through the classical androgen receptor to promote oocyte maturation L. B. Lutz, L. M. Cole, M. K. Gupta, K. W. Kwist, R. J. Auchus, and S. R. Hammes PMCID: PMC61109 Developmental Biology Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos Wendy Dean, Fátima Santos, Miodrag Stojkovic, Valeri Zakhartchenko, Jörn Walter, Eckhard Wolf, and Wolf Reik PMCID: PMC61110 Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse Takeshi Fujiwara, N. Ray Dunn, and Brigid L. M. Hogan PMCID: PMC61111 Ecology Attractive and defensive functions of the ultraviolet pigments of a flower (Hypericum calycinum) Matthew Gronquist, Alexander Bezzerides, Athula Attygalle, Jerrold Meinwald, Maria Eisner, and Thomas Eisner PMCID: PMC61112 Evolution Biological clock in total darkness: The Clock/MOP3 circadian system of the blind subterranean mole rat Aaron Avivi, Urs Albrecht, Henrik Oster, Alma Joel, Avigdor Beiles, and Eviatar Nevo PMCID: PMC61113 Evaluation of methods for detecting recombination from DNA sequences: Computer simulations David Posada and Keith A. Crandall PMCID: PMC61114 Degeneracy and complexity in biological systems Gerald M. Edelman and Joseph A. Gally PMCID: PMC61115 Paternal relatedness and age proximity regulate social relationships among adult female rhesus macaques Anja Widdig, Peter Nürnberg, Michael Krawczak, Wolf Jürgen Streich, and Fred B. Bercovitch PMCID: PMC61116 Evolutionary route to diploidy and sex Erkan Tüzel, Volkan Sevim, and Ayşe Erzan PMCID: PMC61117 Genetics Terminal-repeat retrotransposons in miniature (TRIM) are involved in restructuring plant genomes Claus-Peter Witte, Quang Hien Le, Thomas Bureau, and Amar Kumar PMCID: PMC61118 Diversity of gene expression in adenocarcinoma of the lung Mitchell E. Garber, Olga G. Troyanskaya, Karsten Schluens, Simone Petersen, Zsuzsanna Thaesler, Manuela Pacyna-Gengelbach, Matt van de Rijn, Glenn D. Rosen, Charles M. Perou, Richard I. Whyte, Russ B. Altman, Patrick O. Brown, David Botstein, and Iver Petersen PMCID: PMC61119 Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses Arindam Bhattacharjee, William G. Richards, Jane Staunton, Cheng Li, Stefano Monti, Priya Vasa, Christine Ladd, Javad Beheshti, Raphael Bueno, Michael Gillette, Massimo Loda, Griffin Weber, Eugene J. Mark, Eric S. Lander, Wing Wong, Bruce E. Johnson, Todd R. Golub, David J. Sugarbaker, and Matthew Meyerson PMCID: PMC61120 FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse Kathryn E. Hentges, Baheya Sirry, Anne-Claude Gingeras, Dos Sarbassov, Nahum Sonenberg, David Sabatini, and Andrew S. Peterson PMCID: PMC61121 High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6 Sihong Chen, Sandra H. Bigner, and Paul Modrich PMCID: PMC61122 Impairment of MAD2B–PRCC interaction in mitotic checkpoint defective t(X;1)-positive renal cell carcinomas Marian A. J. Weterman, Jan J. M. van Groningen, Leon Tertoolen, and Ad Geurts van Kessel PMCID: PMC61123 Role of positively charged transmembrane segments in the insertion and assembly of mitochondrial inner-membrane proteins Yann Saint-Georges, Patrice Hamel, Claire Lemaire, and Geneviève Dujardin PMCID: PMC61124 A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice Mark A. Farmer, John P. Sundberg, Ian J. Bristol, Gary A. Churchill, Renhua Li, Charles O. Elson, and Edward H. Leiter PMCID: PMC61125 Immunology Structural basis for autoantibody recognition of phosphatidylserine-β2 glycoprotein I and apoptotic cells Brian A. Cocca, Samarendra N. Seal, Paolo D'Agnillo, Yvonne M. Mueller, Peter D. Katsikis, Joyce Rauch, Martin Weigert, and Marko Z. Radic PMCID: PMC61126 Extraordinary variation in a diversified family of immune-type receptor genes Noel A. Hawke, Jeffrey A. Yoder, Robert N. Haire, M. Gail Mueller, Ronda T. Litman, Ann L. Miracle, Tor Stuge, Linling Shen, Norman Miller, and Gary W. Litman PMCID: PMC61127 Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets Yuri N. Naumov, Keith S. Bahjat, Rudolph Gausling, Roshini Abraham, Mark A. Exley, Yasuhiko Koezuka, Steven B. Balk, Jack L. Strominger, Michael Clare-Salzer, and S. Brian Wilson PMCID: PMC61128 Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival Alain P. Gobert, David J. McGee, Mahmood Akhtar, George L. Mendz, Jamie C. Newton, Yulan Cheng, Harry L. T. Mobley, and Keith T. Wilson PMCID: PMC61129 CD5 expression by B lymphocytes and its regulation upon Epstein–Barr virus transformation David Kaplan, Dawn Smith, Howard Meyerson, Nicole Pecora, and Kristine Lewandowska PMCID: PMC61130 Enhanced delayed-type hypersensitivity and diminished immediate-type hypersensitivity in mice lacking the inducible VPAC2 receptor for vasoactive intestinal peptide Edward J. Goetzl, Julia K. Voice, Sanbing Shen, Glenn Dorsam, Yvonne Kong, Katrine M. West, Christine F. Morrison, and Anthony J. Harmar PMCID: PMC61131 Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination Xiaochuan Chen, Kazuo Kinoshita, and Tasuku Honjo PMCID: PMC61132 PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine Taku Okazaki, Akito Maeda, Hiroyuki Nishimura, Tomohiro Kurosaki, and Tasuku Honjo PMCID: PMC61133 Vaccination, prevention, and treatment of experimental autoimmune neuritis (EAN) by an oligomerized T cell epitope M. Stienekemeier, K. Falk, O. Rötzschke, A. Weishaupt, C. Schneider, K. V. Toyka, R. Gold, and J. L. Strominger PMCID: PMC61134 High-level HIV-1 viremia suppresses viral antigen-specific CD4+ T cell proliferation Andrew C. McNeil, W. Lesley Shupert, Christiana A. Iyasere, Claire W. Hallahan, JoAnn Mican, Richard T. Davey, Jr., and Mark Connors PMCID: PMC61135 Caspase-10 is an initiator caspase in death receptor signaling Jin Wang, Hyung J. Chun, Wilson Wong, David M. Spencer, and Michael J. Lenardo PMCID: PMC61136 Medical Sciences S100A1: A regulator of myocardial contractility Patrick Most, Juliane Bernotat, Philipp Ehlermann, Sven T. Pleger, Michael Reppel, Melanie Börries, Ferraydoon Niroomand, Burkert Pieske, Paul M. L. Janssen, Thomas Eschenhagen, Peter Karczewski, Godfrey L. Smith, Walter J. Koch, Hugo A. Katus, and Andrew Remppis PMCID: PMC61137 Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D3 Anders Nykjaer, John C. Fyfe, Renata Kozyraki, Jörg-Robert Leheste, Christian Jacobsen, Morten S. Nielsen, Pierre J. Verroust, Maria Aminoff, Albert de la Chapelle, Søren K. Moestrup, Rahul Ray, Jørgen Gliemann, Thomas E. Willnow, and Erik I. Christensen PMCID: PMC61138 BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia Stephan M. Tanner, Jamie L. Austin, Gustavo Leone, Laura J. Rush, Christoph Plass, Kristiina Heinonen, Krzysztof Mrózek, Heinz Sill, Sakari Knuutila, Jonathan E. Kolitz, Kellie J. Archer, Michael A. Caligiuri, Clara D. Bloomfield, and Albert de la Chapelle PMCID: PMC61139 From the Cover:
Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons J. Gerardo García-Lerma, Soumya Nidtha, Katherine Blumoff, Hillard Weinstock, and Walid Heneine PMCID: PMC61140 Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice Kevin Goudy, Sihong Song, Clive Wasserfall, Y. Clare Zhang, Matthias Kapturczak, Andrew Muir, Matthew Powers, Marda Scott-Jorgensen, Martha Campbell-Thompson, James M. Crawford, Tamir M. Ellis, Terence R. Flotte, and Mark A. Atkinson PMCID: PMC61141 Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors H. Eric Xu, Millard H. Lambert, Valerie G. Montana, Kelli D. Plunket, Linda B. Moore, Jon L. Collins, Jeffery A. Oplinger, Steven A. Kliewer, Robert T. Gampe, Jr., David D. McKee, John T. Moore, and Timothy M. Willson PMCID: PMC61142 Plasma membrane rafts play a critical role in HIV-1 assembly and release Akira Ono and Eric O. Freed PMCID: PMC61143 Host cell factor requirement for hepatitis C virus enzyme maturation Lloyd Waxman, Michael Whitney, Brian A. Pollok, Lawrence C. Kuo, and Paul L. Darke PMCID: PMC61144 Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis Stefano Fiorucci, Andrea Mencarelli, Barbara Palazzetti, Eleonora Distrutti, Nathalie Vergnolle, Morley D. Hollenberg, John L. Wallace, Antonio Morelli, and Giuseppe Cirino PMCID: PMC61145 Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis Christine Beeton, Heike Wulff, Jocelyne Barbaria, Olivier Clot-Faybesse, Michael Pennington, Dominique Bernard, Michael D. Cahalan, K. George Chandy, and Evelyne Béraud PMCID: PMC61146 Escaping the stem cell compartment: Sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations Wengeng Zhang, Eva Remenyik, Daniel Zelterman, Douglas E. Brash, and Norbert M. Wikonkal PMCID: PMC61147 Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B Yoshio Tomizawa, Yoshitaka Sekido, Masashi Kondo, Boning Gao, Jun Yokota, Joëlle Roche, Harry Drabkin, Michael I. Lerman, Adi F. Gazdar, and John D. Minna PMCID: PMC61148 Up-regulation of TNF-producing T cells in the bone marrow: A key mechanism by which estrogen deficiency induces bone loss in vivo Cristiana Roggia, Yuhao Gao, Simone Cenci, M. Neale Weitzmann, Gianluca Toraldo, Giancarlo Isaia, and Roberto Pacifici PMCID: PMC61149 The pattern of gene expression in human CD34+ stem/progenitor cells Guolin Zhou, Jianjun Chen, Sanggyu Lee, Terry Clark, Janet D. Rowley, and San Ming Wang PMCID: PMC61150 Microbiology Molecular basis for defective glycosylation and Pseudomonas pathogenesis in cystic fibrosis lung J. F. Poschet, J. C. Boucher, L. Tatterson, J. Skidmore, R. W. Van Dyke, and V. Deretic PMCID: PMC61151 Directed polar secretion of protease from single cells of Vibrio cholerae via the type II secretion pathway Maria E. Scott, Zain Y. Dossani, and Maria Sandkvist PMCID: PMC61152 Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes Robert J. Belland, Marci A. Scidmore, Deborah D. Crane, Daniel M. Hogan, William Whitmire, Grant McClarty, and Harlan D. Caldwell PMCID: PMC61153 Identification of a developmental chemoattractant in Myxococcus xanthus through metabolic engineering Daniel B. Kearns, Andre Venot, Pamela J. Bonner, Brian Stevens, Geert-Jan Boons, and Lawrence J. Shimkets PMCID: PMC61154 Neurobiology Reafferent copies of imitated actions in the right superior temporal cortex Marco Iacoboni, Lisa M. Koski, Marcel Brass, Harold Bekkering, Roger P. Woods, Marie-Charlotte Dubeau, John C. Mazziotta, and Giacomo Rizzolatti PMCID: PMC61155 Identification of neuropeptide-like protein gene families in Caenorhabditis elegans and other species Arif N. Nathoo, Rachael A. Moeller, Beth A. Westlund, and Anne C. Hart PMCID: PMC61156 Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin Merab Kokaia, Kristina Holmberg, Avtandil Nanobashvili, Zhi-Qing D. Xu, Zaal Kokaia, Urban Lendahl, Susanne Hilke, Elvar Theodorsson, Ulrika Kahl, Tamas Bartfai, Olle Lindvall, and Tomas Hökfelt PMCID: PMC61157 Dynamic control of auditory activity during sleep: Correlation between song response and EEG Teresa A. Nick and Masakazu Konishi PMCID: PMC61158 Activation of the epsilon isoform of protein kinase C in the mammalian nerve terminal Naoto Saitoh, Tetsuya Hori, and Tomoyuki Takahashi PMCID: PMC61159 Assessment of the developmental totipotency of neural cells in the cerebral cortex of mouse embryo by nuclear transfer Yukiko Yamazaki, Hatsune Makino, Kayoko Hamaguchi-Hamada, Shun Hamada, Hidehiko Sugino, Eihachiro Kawase, Takaki Miyata, Masaharu Ogawa, Ryuzo Yanagimachi, and Takeshi Yagi PMCID: PMC61160 Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans Kenneth P. Wright, Jr., Rod J Hughes, Richard E. Kronauer, Derk-Jan Dijk, and Charles A. Czeisler PMCID: PMC61161 The synthetic enantiomer of pregnenolone sulfate is very active on memory in rats and mice, even more so than its physiological neurosteroid counterpart: Distinct mechanisms? Yvette Akwa, Nathalie Ladurelle, Douglas F. Covey, and Etienne-Emile Baulieu PMCID: PMC61162 SNAP-29: A general SNARE protein that inhibits SNARE disassembly and is implicated in synaptic transmission Qingning Su, Sumiko Mochida, Jin-Hua Tian, Rashi Mehta, and Zu-Hang Sheng PMCID: PMC61163 Low amplification and fast visual pigment phosphorylation as mechanisms characterizing cone photoresponses Shuji Tachibanaki, Sawae Tsushima, and Satoru Kawamura PMCID: PMC61164 The ability of inferior colliculus neurons to signal differences in interaural delay Bernt C. Skottun, Trevor M. Shackleton, Robert H. Arnott, and Alan R. Palmer PMCID: PMC61165 Identification of a trafficking determinant localized to the Kv1 potassium channel pore Louis N. Manganas, Qiang Wang, Robert H. Scannevin, Dana E. Antonucci, Kenneth J. Rhodes, and James S. Trimmer PMCID: PMC61166 Corticofugal modulation of duration-tuned neurons in the midbrain auditory nucleus in bats Xiaofeng Ma and Nobuo Suga PMCID: PMC61167 The expression of cerebellar LTD in culture is not associated with changes in AMPA-receptor kinetics, agonist affinity, or unitary conductance David J. Linden PMCID: PMC61168 Pharmacology Distinction between signaling mechanisms in lipid rafts vs. caveolae Grzegorz Sowa, Marc Pypaert, and William C. Sessa PMCID: PMC61169 Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P-glycoprotein Roman V. Kondratov, Pavel G. Komarov, Yigal Becker, Ariel Ewenson, and Andrei V. Gudkov PMCID: PMC61170 Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene Ying-Xian Pan, Jin Xu, Loriann Mahurter, Elizabeth Bolan, Mingming Xu, and Gavril W. Pasternak PMCID: PMC61171 The anti-HIV pentameric pseudopeptide HB-19 is preferentially taken up in vivo by lymphoid organs where it forms a complex with nucleolin B. Krust, R. Vienet, A. Cardona, C. Rougeot, E. Jacotot, C. Callebaut, G. Guichard, J. P. Briand, J. M. Grognet, A. G. Hovanessian, and L. Edelman PMCID: PMC61173 Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice Masahisa Yamada, Kathryn G. Lamping, Alokesh Duttaroy, Weilie Zhang, Yinghong Cui, Frank P. Bymaster, David L. McKinzie, Christian C. Felder, Chu-Xia Deng, Frank M. Faraci, and Jürgen Wess PMCID: PMC61174 Physiology The dissociation of acetylcholine from open nicotinic receptor channels Claudio Grosman and Anthony Auerbach PMCID: PMC61175 Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein John D. Neely, Mahmood Amiry-Moghaddam, Ole Petter Ottersen, Stanley C. Froehner, Peter Agre, and Marvin E. Adams PMCID: PMC61176 Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation Carissa M. Krane, Christopher N. Fortner, Arthur R. Hand, Dennis W. McGraw, John N. Lorenz, Susan E. Wert, Jennifer E. Towne, Richard J. Paul, Jeffrey A. Whitsett, and Anil G. Menon PMCID: PMC61177 From the Cover:
Compartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cells Pingbo Huang, Eduardo R. Lazarowski, Robert Tarran, Sharon L. Milgram, Richard C. Boucher, and M. Jackson Stutts PMCID: PMC61178 Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection Anthony J. Kanai, Linda L. Pearce, Paula R. Clemens, Lori A. Birder, Michelle M. VanBibber, So-Young Choi, William C. de Groat, and Jim Peterson PMCID: PMC61179 From the Cover:
Estrogen action and male fertility: Roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function Qing Zhou, Lane Clarke, Rong Nie, Kay Carnes, Li-Wen Lai, Yeong-Hau H. Lien, Alan Verkman, Dennis Lubahn, Jane S. Fisher, Benita S. Katzenellenbogen, and Rex A. Hess PMCID: PMC61180 Plant Biology The role of ABA and the transpiration stream in the regulation of the osmotic water permeability of leaf cells Raphaël Morillon and Maarten J. Chrispeels PMCID: PMC61181 Identification and characterization of a mitochondrial thioredoxin system in plants Christophe Laloi, Naganand Rayapuram, Yvette Chartier, Jean-Michel Grienenberger, Géraldine Bonnard, and Yves Meyer PMCID: PMC61182 AtHKT1 is a salt tolerance determinant that controls Na+ entry into plant roots Ana Rus, Shuji Yokoi, Altanbadralt Sharkhuu, Muppala Reddy, Byeong-ha Lee, Tracie K. Matsumoto, Hisashi Koiwa, Jian-Kang Zhu, Ray A. Bressan, and Paul M. Hasegawa PMCID: PMC61183 Polycomb repression of flowering during early plant development Tetsu Kinoshita, John J. Harada, Robert B. Goldberg, and Robert L. Fischer PMCID: PMC61184 The DELLA motif is essential for gibberellin-induced degradation of RGA Alyssa Dill, Hou-Sung Jung, and Tai-ping Sun PMCID: PMC61185 Chlorophyll b can serve as the major pigment in functional photosystem II complexes of cyanobacteria Hong Xu, Dmitrii Vavilin, and Wim Vermaas PMCID: PMC61186 Regulation of cyclic peptide biosynthesis in a plant pathogenic fungus by a novel transcription factor Kerry F. Pedley and Jonathan D. Walton PMCID: PMC61187 Social Sciences Anthropology Radiocarbon evidence for maritime pioneer colonization at the origins of farming in west Mediterranean Europe João Zilhão PMCID: PMC61188 Corrections Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14186. Published online 2001 November 13. PMCID: PMC61056 Corrects: Aurel Betz, et al. A Drosophila PIAS homologue negatively
regulates stat92E. Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9563–9568. Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14186. PMCID: PMC61057 Corrects: Jason C. Mills, et al. The intestinal stem cell niche: There grows the neighborhood. Proc Natl Acad Sci U S A. 2001 October 23; 98(22): 12334–12336. Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14186. Published online 2001 November 13. PMCID: PMC61058 Corrects: Georgios Amexis, et al. Quantitative mutant analysis of viral quasispecies by chip-based matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry. Proc Natl Acad Sci U S A. 2001 October 9; 98(21): 12097–12102. Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14186. PMCID: PMC61059 Corrects: Teresa Gilewski, et al. Immunization of metastatic breast cancer patients with a fully
synthetic globo H conjugate: A phase I trial. Proc Natl Acad Sci U S A. 2001 March 13; 98(6): 3270–3275. Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14186. Published online 2001 November 13. PMCID: PMC61060 Corrects: Surajit Ganguly, et al. Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis. Proc Natl Acad Sci U S A. 2001 July 3; 98(14): 8083–8088. Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14186. Published online 2001 November 13. PMCID: PMC61061 Corrects: Amy Malick, et al. A neurohistochemical blueprint for pain-induced loss of appetite. Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9930–9935. |
