| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2008 April 1; 105(13): 4963–4964. doi: 10.1073/iti1308105.PMCID: PMC2278214 Commentaries Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool Roger A. Davis and Alan D. Attie PMCID: PMC2278196 The different views from small angles Jill Trewhella PMCID: PMC2278209 Profile Profile of Bonnie L. Bassler Farooq Ahmed PMCID: PMC2278219 Physical Sciences Applied Mathematics From time series to complex networks: The visibility graph Lucas Lacasa, Bartolo Luque, Fernando Ballesteros, Jordi Luque, and Juan Carlos Nuño PMCID: PMC2278201 Transcriptional control of noise in gene expression Álvaro Sánchez and Jané Kondev PMCID: PMC2278180 Engineering From the Cover:
Organic transistors manufactured using inkjet technology with subfemtoliter accuracy Tsuyoshi Sekitani, Yoshiaki Noguchi, Ute Zschieschang, Hagen Klauk, and Takao Someya PMCID: PMC2278200 Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm Pak Kin Wong, Fuqu Yu, Arash Shahangian, Genhong Cheng, Ren Sun, and Chih-Ming Ho PMCID: PMC2278193 Geology Regulating continent growth and composition by chemical weathering Cin-Ty Aeolus Lee, Douglas M. Morton, Mark G. Little, Ronald Kistler, Ulyana N. Horodyskyj, William P. Leeman, and Arnaud Agranier PMCID: PMC2278177 Constraints on the early uplift history of the Tibetan Plateau Chengshan Wang, Xixi Zhao, Zhifei Liu, Peter C. Lippert, Stephan A. Graham, Robert S. Coe, Haisheng Yi, Lidong Zhu, Shun Liu, and Yalin Li PMCID: PMC2278176 Physics Soft glassy rheology of supercooled molecular liquids Rob Zondervan, Ted Xia, Harmen van der Meer, Cornelis Storm, Florian Kulzer, Wim van Saarloos, and Michel Orrit PMCID: PMC2278182 A new phase of solid iodine with different molecular covalent bonds Qifeng Zeng, Zhi He, Xiaojiao San, Yanming Ma, Fubo Tian, Tian Cui, Bingbing Liu, Guangtian Zou, and Ho-kwang Mao PMCID: PMC2278223 Biological Sciences Biochemistry A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes Shane R. Wilkinson, Martin C. Taylor, David Horn, John M. Kelly, and Ian Cheeseman PMCID: PMC2278226 The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus Lily Agranat, Oleg Raitskin, Joseph Sperling, and Ruth Sperling PMCID: PMC2278206 Molecular recognition of parathyroid hormone by its G protein-coupled receptor Augen A. Pioszak and H. Eric Xu PMCID: PMC2278174 Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtB Arnaud Javelle, Domenico Lupo, Pierre Ripoche, Tim Fulford, Mike Merrick, and Fritz K. Winkler PMCID: PMC2278191 X-ray crystal structure of the polymerase domain of the bacteriophage N4 virion RNA polymerase Katsuhiko S. Murakami, Elena K. Davydova, and Lucia B. Rothman-Denes PMCID: PMC2278199 Crystal structure of DNA-bound Co(III)·bleomycin B2: Insights on intercalation and minor groove binding Kristie D. Goodwin, Mark A. Lewis, Eric C. Long, and Millie M. Georgiadis PMCID: PMC2278181 Interconversion between two unrelated protein folds in the lymphotactin native state Robbyn L. Tuinstra, Francis C. Peterson, Snjezana Kutlesa, E. Sonay Elgin, Michael A. Kron, and Brian F. Volkman PMCID: PMC2278211 Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3β Subhasis Mohanty, Terrence Town, Tomohito Yagi, Christina Scheidig, Kelvin Y. Kwan, Heather G. Allore, Richard A. Flavell, and Albert C. Shaw PMCID: PMC2278186 A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5 Robert Ernst, Petra Kueppers, Cornelia M. Klein, Tobias Schwarzmueller, Karl Kuchler, and Lutz Schmitt PMCID: PMC2278221 Biophysics Absence of equilibrium cluster phase in concentrated lysozyme solutions Anuj Shukla, Efstratios Mylonas, Emanuela Di Cola, Stephanie Finet, Peter Timmins, Theyencheri Narayanan, and Dmitri I. Svergun PMCID: PMC2278215 Transcriptional control of noise in gene expression Álvaro Sánchez and Jané Kondev PMCID: PMC2278180 Mechanism and kinetics of pore formation in membranes by water-soluble amphipathic peptides Ming-Tao Lee, Wei-Chin Hung, Fang-Yu Chen, and Huey W. Huang PMCID: PMC2278198 Vitrification is essential for anhydrobiosis in an African chironomid, Polypedilum vanderplanki Minoru Sakurai, Takao Furuki, Ken-ichi Akao, Daisuke Tanaka, Yuichi Nakahara, Takahiro Kikawada, Masahiko Watanabe, and Takashi Okuda PMCID: PMC2278217 Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation Wolfgang Hoyer, Caroline Grönwall, Andreas Jonsson, Stefan Ståhl, and Torleif Härd PMCID: PMC2278213 Cell Biology Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm Pak Kin Wong, Fuqu Yu, Arash Shahangian, Genhong Cheng, Ren Sun, and Chih-Ming Ho PMCID: PMC2278193 Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease Bita Sahaf, Kondala Atkuri, Kartoosh Heydari, Meena Malipatlolla, Jay Rappaport, Emmanuel Regulier, Leonard A. Herzenberg, and Leonore A. Herzenberg PMCID: PMC2278183 Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation Avigail D. Amsel, Moran Rathaus, Noam Kronman, and Haim Y. Cohen PMCID: PMC2278173 Ecology From the Cover:
Surprising migration and population size dynamics in ancient Iberian brown bears (Ursus arctos) Cristina E. Valdiosera, José Luis García-Garitagoitia, Nuria Garcia, Ignacio Doadrio, Mark G. Thomas, Catherine Hänni, Juan-Luis Arsuaga, Ian Barnes, Michael Hofreiter, Ludovic Orlando, and Anders Götherström PMCID: PMC2278212 Anthropogenic increase in carbon dioxide compromises plant defense against invasive insects Jorge A. Zavala, Clare L. Casteel, Evan H. DeLucia, and May R. Berenbaum PMCID: PMC2278205 Diversity predicts stability and resource use efficiency in natural phytoplankton communities Robert Ptacnik, Angelo G. Solimini, Tom Andersen, Timo Tamminen, Pål Brettum, Liisa Lepistö, Eva Willén, and Seppo Rekolainen PMCID: PMC2278227 Evolution Regulating continent growth and composition by chemical weathering Cin-Ty Aeolus Lee, Douglas M. Morton, Mark G. Little, Ronald Kistler, Ulyana N. Horodyskyj, William P. Leeman, and Arnaud Agranier PMCID: PMC2278177 Extreme resistance of bdelloid rotifers to ionizing radiation Eugene Gladyshev and Matthew Meselson PMCID: PMC2278216 Evidence for degenerate tetraploidy in bdelloid rotifers David B. Mark Welch, Jessica L. Mark Welch, and Matthew Meselson PMCID: PMC2278229 Genetic royal cheats in leaf-cutting ant societies William O. H. Hughes and Jacobus J. Boomsma PMCID: PMC2278208 Genetics Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP Guillaume M. Hautbergue, Ming-Lung Hung, Alexander P. Golovanov, Lu-Yun Lian, and Stuart A. Wilson PMCID: PMC2278192 Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene Sue Mei Tan-Wong, Juliet D. French, Nicholas J. Proudfoot, and Melissa A. Brown PMCID: PMC2278189 MiR-15a and miR-16-1 cluster functions in human leukemia George A. Calin, Amelia Cimmino, Muller Fabbri, Manuela Ferracin, Sylwia E. Wojcik, Masayoshi Shimizu, Cristian Taccioli, Nicola Zanesi, Ramiro Garzon, Rami I. Aqeilan, Hansjuerg Alder, Stefano Volinia, Laura Rassenti, Xiuping Liu, Chang-gong Liu, Thomas J. Kipps, Massimo Negrini, and Carlo M. Croce PMCID: PMC2278188 Immunology Amino acid copolymer-specific IL-10-secreting regulatory T cells that ameliorate autoimmune diseases in mice Joel N. H. Stern, Derin B. Keskin, Hong Zhang, HuiJuan Lv, Zenichiro Kato, and Jack L. Strominger PMCID: PMC2278190 Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice Jisen Huai, Elke Firat, Ahmed Nil, Daniele Million, Simone Gaedicke, Benoit Kanzler, Marina Freudenberg, Peter van Endert, Gabriele Kohler, Heike L. Pahl, Peter Aichele, Klaus Eichmann, and Gabriele Niedermann PMCID: PMC2278225 Microbial carbohydrate depolymerization by antigen-presenting cells: Deamination prior to presentation by the MHCII pathway Jinyou Duan, Fikri Y. Avci, and Dennis L. Kasper PMCID: PMC2278222 Antigen kinetics determines immune reactivity Pål Johansen, Tazio Storni, Lorna Rettig, Zhiyong Qiu, Ani Der-Sarkissian, Kent A. Smith, Vania Manolova, Karl S. Lang, Gabriela Senti, Beat Müllhaupt, Tilman Gerlach, Roberto F. Speck, Adrian Bot, and Thomas M. Kündig PMCID: PMC2278203 CD11b expression distinguishes sequential stages of peritoneal B-1 development Eliver Eid Bou Ghosn, Yang Yang, James Tung, Leonard A. Herzenberg, and Leonore A. Herzenberg PMCID: PMC2278228 IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis SangKon Oh, Liyanage P. Perera, Masaki Terabe, Ling Ni, Thomas A. Waldmann, and Jay A. Berzofsky PMCID: PMC2278231 The vitamin D receptor is required for iNKT cell development Sanhong Yu and Margherita T. Cantorna PMCID: PMC2278204 Medical Sciences From the Cover:
Identification of noninvasive imaging surrogates for brain tumor gene-expression modules Maximilian Diehn, Christine Nardini, David S. Wang, Susan McGovern, Mahesh Jayaraman, Yu Liang, Kenneth Aldape, Soonmee Cha, and Michael D. Kuo PMCID: PMC2278224 Structural basis of GM1 ganglioside recognition by simian virus 40 Ursula Neu, Karin Woellner, Guenter Gauglitz, and Thilo Stehle PMCID: PMC2278218 Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies Luciano Merlini, Alessia Angelin, Tania Tiepolo, Paola Braghetta, Patrizia Sabatelli, Alessandra Zamparelli, Alessandra Ferlini, Nadir M. Maraldi, Paolo Bonaldo, and Paolo Bernardi PMCID: PMC2278179 Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors Richard Einstein, Heather Jordan, Weiyin Zhou, Michael Brenner, Esther G. Moses, and Stephen B. Liggett PMCID: PMC2278184 Distinct nuclear and cytoplasmic functions of androgen receptor cofactor p44 and association with androgen-independent prostate cancer Yi Peng, Fei Chen, Jonathan Melamed, Luis Chiriboga, Jianjun Wei, Xiangtian Kong, Maureen Mcleod, Yirong Li, Caihong X. Li, Alice Feng, Michael J. Garabedian, Zhengxin Wang, Robert G. Roeder, and Peng Lee PMCID: PMC2278178 Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras Katrina Podsypanina, Katerina Politi, Levi J. Beverly, and Harold E. Varmus PMCID: PMC2278195 Homozygous deletion of glycogen synthase kinase 3β bypasses senescence allowing Ras transformation of primary murine fibroblasts Shuying Liu, Xianjun Fang, Hassan Hall, Shuangxing Yu, Debra Smith, Zhimin Lu, Dexing Fang, Jinsong Liu, L. Clifton Stephens, James R. Woodgett, and Gordon B. Mills PMCID: PMC2278194 Microbiology COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro Alfred G. Tamayo, Ajit Bharti, Carolina Trujillo, Robert Harrison, and John R. Murphy PMCID: PMC2278175 Neuroscience CASY-1, an ortholog of calsyntenins/alcadeins, is essential for learning in Caenorhabditis elegans Daisuke D. Ikeda, Yukan Duan, Masahiro Matsuki, Hirofumi Kunitomo, Harald Hutter, Edward M. Hedgecock, and Yuichi Iino PMCID: PMC2278220 Physiology Osteocalcin differentially regulates β cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice Mathieu Ferron, Eiichi Hinoi, Gerard Karsenty, and Patricia Ducy PMCID: PMC2278202 Plant Biology Plant adaptation to fluctuating environment and biomass production are strongly dependent on guard cell potassium channels Anne Lebaudy, Alain Vavasseur, Eric Hosy, Ingo Dreyer, Nathalie Leonhardt, Jean-Baptiste Thibaud, Anne-Aliénor Véry, Thierry Simonneau, and Hervé Sentenac PMCID: PMC2278230 Psychology Variation at the mu-opioid receptor gene (OPRM1) influences attachment behavior in infant primates Christina S. Barr, Melanie L. Schwandt, Stephen G. Lindell, J. Dee Higley, Dario Maestripieri, David Goldman, Stephen J. Suomi, and Markus Heilig PMCID: PMC2278187 Social Sciences Anthropology From the Cover:
Four-thousand-year-old gold artifacts from the Lake Titicaca basin, southern Peru Mark Aldenderfer, Nathan M. Craig, Robert J. Speakman, and Rachel Popelka-Filcoff PMCID: PMC2278197 Directly dated starch residues document early formative maize (Zea mays L.) in tropical Ecuador Sonia Zarrillo, Deborah M. Pearsall, J. Scott Raymond, Mary Ann Tisdale, and Dugane J. Quon PMCID: PMC2278185 Psychology From the Cover:
Intuitive statistics by 8-month-old infants Fei Xu and Vashti Garcia PMCID: PMC2278207 Social Sciences The rise and fall of excess male infant mortality Greg L. Drevenstedt, Eileen M. Crimmins, Sarinnapha Vasunilashorn, and Caleb E. Finch PMCID: PMC2278210 |
