| | This journal provides immediate access to some articles. From the Academy Editorial Crossing borders, challenging boundaries: Reflections on a decade of exchange at the Chinese–American Kavli Frontiers of Science Symposium Chunli Bai and Jinghua Cao PMCID: PMC2234094 This Week in PNAS Proc Natl Acad Sci U S A. 2008 January 29; 105(4): 1099–1100. doi: 10.1073/iti0408105.PMCID: PMC2234093 Commentaries Holes, objects, and the left hemisphere Sheng He PMCID: PMC2234095 The soft framework of the cellular machine D. A. Weitz and P. A. Janmey PMCID: PMC2234096 Slow-wave sleep, diabetes, and the sympathetic nervous system Derk-Jan Dijk PMCID: PMC2234097 Pandemic lessons from Iceland Scott F. Dowell and Joseph S. Bresee PMCID: PMC2234098 Physical Sciences Applied Mathematics Maps of random walks on complex networks reveal community structure Martin Rosvall and Carl T. Bergstrom PMCID: PMC2234100 Energy of Tycho's Supernova Remnant is increasing with time Grigory Isaakovich Barenblatt PMCID: PMC2234101 Mathematics Nilpotent orbits in classical Lie algebras over F2n and the Springer correspondence Ting Xue PMCID: PMC2234102 Physics INAUGURAL ARTICLE by a Recently Elected Academy Member: Phase separation and liquid crystallization of complementary sequences in mixtures of nanoDNA oligomers Giuliano Zanchetta, Michi Nakata, Marco Buscaglia, Tommaso Bellini, and Noel A. Clark PMCID: PMC2234099 Physiology Transient regulation of transport by pericytes in venular microvessels via trapped microdomains X. Zhang, R. H. Adamson, F. E. Curry, and S. Weinbaum PMCID: PMC2234146 Biological Sciences Applied Biological Sciences Generation of biologically contained Ebola viruses Peter Halfmann, Jin Hyun Kim, Hideki Ebihara, Takeshi Noda, Gabriele Neumann, Heinz Feldmann, and Yoshihiro Kawaoka PMCID: PMC2234103 Biochemistry From the Cover:
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2 Anutosh Chakraborty, Michael A. Koldobskiy, Katherine M. Sixt, Krishna R. Juluri, Asif K. Mustafa, Adele M. Snowman, Damian B. van Rossum, Randen L. Patterson, and Solomon H. Snyder PMCID: PMC2234104 The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va Xiang-dong Li, Hyun Suk Jung, Qizhi Wang, Reiko Ikebe, Roger Craig, and Mitsuo Ikebe PMCID: PMC2234105 Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1 Matthew P. Meyer, Diana R. Tomchick, and Judith P. Klinman PMCID: PMC2234106 Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products S. M. Simon, F. J. R. Sousa, R. Mohana-Borges, and G. C. Walker PMCID: PMC2234107 Efficient coupling of catalysis and dynamics in the E1 component of Escherichia coli pyruvate dehydrogenase multienzyme complex Sachin Kale, Gözde Ulas, Jaeyoung Song, Gary W. Brudvig, William Furey, and Frank Jordan PMCID: PMC2234108 BiP mutants that are unable to interact with endoplasmic reticulum DnaJ proteins provide insights into interdomain interactions in BiP Walid Awad, Isaac Estrada, Ying Shen, and Linda M. Hendershot PMCID: PMC2234109 Mutational specificity and genetic control of replicative bypass of an abasic site in yeast Vincent Pagès, Robert E. Johnson, Louise Prakash, and Satya Prakash PMCID: PMC2234110 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Phase separation and liquid crystallization of complementary sequences in mixtures of nanoDNA oligomers Giuliano Zanchetta, Michi Nakata, Marco Buscaglia, Tommaso Bellini, and Noel A. Clark PMCID: PMC2234099 Selective aluminum passivation for targeted immobilization of single DNA polymerase molecules in zero-mode waveguide nanostructures Jonas Korlach, Patrick J. Marks, Ronald L. Cicero, Jeremy J. Gray, Devon L. Murphy, Daniel B. Roitman, Thang T. Pham, Geoff A. Otto, Mathieu Foquet, and Stephen W. Turner PMCID: PMC2234111 Resurrection of the flagellar rotary motor near zero load Junhua Yuan and Howard C. Berg PMCID: PMC2234112 A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Eleonore von Castelmur, Marco Marino, Dmitri I. Svergun, Laurent Kreplak, Zöhre Ucurum-Fotiadis, Petr V. Konarev, Alexandre Urzhumtsev, Dietmar Labeit, Siegfried Labeit, and Olga Mayans PMCID: PMC2234113 How subunit coupling produces the γ-subunit rotary motion in F1-ATPase Jingzhi Pu and Martin Karplus PMCID: PMC2234114 Mechanism of selectivity in aquaporins and aquaglyceroporins Jochen S. Hub and Bert L. de Groot PMCID: PMC2234115 Unique elastic properties of the spectrin tetramer as revealed by multiscale coarse-grained modeling Dina T. Mirijanian and Gregory A. Voth PMCID: PMC2234116 Cell Biology From the Cover:
Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass Edward C. Hsiao, Benjamin M. Boudignon, Wei C. Chang, Margaret Bencsik, Jeffrey Peng, Trieu D. Nguyen, Carlota Manalac, Bernard P. Halloran, Bruce R. Conklin, and Robert A. Nissenson PMCID: PMC2234117 Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence Thomas M. Johnson, Kristin Meade, Navneeta Pathak, Michelle R. Marques, and Laura D. Attardi PMCID: PMC2234118 Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae Barbara L. Barbeta, Alan T. Marshall, Amanda D. Gillon, David J. Craik, and Marilyn A. Anderson PMCID: PMC2234119 High glucose induces adipogenic differentiation of muscle-derived stem cells Paola Aguiari, Sara Leo, Barbara Zavan, Vincenzo Vindigni, Alessandro Rimessi, Katiuscia Bianchi, Chiara Franzin, Roberta Cortivo, Marco Rossato, Roberto Vettor, Giovanni Abatangelo, Tullio Pozzan, Paolo Pinton, and Rosario Rizzuto PMCID: PMC2234120 Ecology From the Cover:
Interaction ruling animal collective behavior depends on topological rather than metric distance: Evidence from a field study M. Ballerini, N. Cabibbo, R. Candelier, A. Cavagna, E. Cisbani, I. Giardina, V. Lecomte, A. Orlandi, G. Parisi, A. Procaccini, M. Viale, and V. Zdravkovic PMCID: PMC2234121 Engineering Transient regulation of transport by pericytes in venular microvessels via trapped microdomains X. Zhang, R. H. Adamson, F. E. Curry, and S. Weinbaum PMCID: PMC2234146 Evolution The oldest platypus and its bearing on divergence timing of the platypus and echidna clades Timothy Rowe, Thomas H. Rich, Patricia Vickers-Rich, Mark Springer, and Michael O. Woodburne PMCID: PMC2234122 Preferential protection of protein interaction network hubs in yeast: Evolved functionality of genetic redundancy Ran Kafri, Orna Dahan, Jonathan Levy, and Yitzhak Pilpel PMCID: PMC2234123 Variation in neural V1aR predicts sexual fidelity and space use among male prairie voles in semi-natural settings Alexander G. Ophir, Jerry O. Wolff, and Steven M. Phelps PMCID: PMC2234124 Genetics Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish Kazuhide Asakawa, Maximiliano L. Suster, Kanta Mizusawa, Saori Nagayoshi, Tomoya Kotani, Akihiro Urasaki, Yasuyuki Kishimoto, Masahiko Hibi, and Koichi Kawakami PMCID: PMC2234125 Immunology The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes Claudia R. Oliva, Melissa K. Swiecki, Corinne E. Griguer, Mark W. Lisanby, Daniel C. Bullard, Charles L. Turnbough, Jr., and John F. Kearney PMCID: PMC2234126 B-cell receptor activation inhibits AID expression through calmodulin inhibition of E-proteins Jannek Hauser, Natalia Sveshnikova, Anders Wallenius, Sanna Baradaran, Juha Saarikettu, and Thomas Grundström PMCID: PMC2234127 SAP expression in T cells, not in B cells, is required for humoral immunity André Veillette, Shaohua Zhang, Xiaochu Shi, Zhongjun Dong, Dominique Davidson, and Ming-Chao Zhong PMCID: PMC2234128 Signal processing by its coil zipper domain activates IKKγ Stuart Bloor, Grigor Ryzhakov, Sebastian Wagner, P. Jonathan G. Butler, David L. Smith, Rebekka Krumbach, Ivan Dikic, and Felix Randow PMCID: PMC2234129 MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma Masahisa Jinushi, Matthew Vanneman, Nikhil C. Munshi, Yu-Tzu Tai, Rao H. Prabhala, Jerome Ritz, Donna Neuberg, Kenneth C. Anderson, Daniel Ruben Carrasco, and Glenn Dranoff PMCID: PMC2234130 Medical Sciences The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7 Jennifer R. Gatchel, Kei Watase, Christina Thaller, James P. Carson, Paymaan Jafar-Nejad, Chad Shaw, Tao Zu, Harry T. Orr, and Huda Y. Zoghbi PMCID: PMC2234131 Hepatic NF-κB essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis F. Thomas Wunderlich, Tom Luedde, Stephan Singer, Marc Schmidt-Supprian, Julia Baumgartl, Peter Schirmacher, Manolis Pasparakis, and Jens C. Brüning PMCID: PMC2234132 From the Cover:
Lessons from the past: Familial aggregation analysis of fatal pandemic influenza (Spanish flu) in Iceland in 1918 Magnús Gottfredsson, Bjarni V. Halldórsson, Stefán Jónsson, Már Kristjánsson, Kristleifur Kristjánsson, Karl G. Kristinsson, Arthur Löve, Thorsteinn Blöndal, Cécile Viboud, Sverrir Thorvaldsson, Agnar Helgason, Jeffrey R. Gulcher, Kári Stefánsson, and Ingileif Jónsdóttir PMCID: PMC2234133 An essential role for orexins in emergence from general anesthesia Max B. Kelz, Yi Sun, Jingqiu Chen, Qing Cheng Meng, Jason T. Moore, Sigrid C. Veasey, Shelley Dixon, Marcus Thornton, Hiromasa Funato, and Masashi Yanagisawa PMCID: PMC2234134 Mast cell renin and a local renin–angiotensin system in the airway: Role in bronchoconstriction Arul Veerappan, Alicia C. Reid, Racha Estephan, Nathan O'Connor, Maria Thadani-Mulero, Mariselis Salazar-Rodriguez, Roberto Levi, and Randi B. Silver PMCID: PMC2234135 Protection against cerebral malaria by the low-molecular-weight thiol pantethine Marie-France Penet, Mhamad Abou-Hamdan, Nicolas Coltel, Emilie Cornille, Georges E. Grau, Max de Reggi, and Bouchra Gharib PMCID: PMC2234136 Microbiology From the Cover:
Epidemic community-associated methicillin-resistant Staphylococcus aureus: Recent clonal expansion and diversification Adam D. Kennedy, Michael Otto, Kevin R. Braughton, Adeline R. Whitney, Liang Chen, Barun Mathema, Jose R. Mediavilla, Kelly A. Byrne, Larye D. Parkins, Fred C. Tenover, Barry N. Kreiswirth, James M. Musser, and Frank R. DeLeo PMCID: PMC2234137 Neuroscience Role of GSK3β in behavioral abnormalities induced by serotonin deficiency Jean-Martin Beaulieu, Xiaodong Zhang, Ramona M. Rodriguiz, Tatyana D. Sotnikova, Michael J. Cools, William C. Wetsel, Raul R. Gainetdinov, and Marc G. Caron PMCID: PMC2234138 A Caenorhabditis elegans allatostatin/galanin-like receptor NPR-9 inhibits local search behavior in response to feeding cues William G. Bendena, Jeff R. Boudreau, Tony Papanicolaou, Matt Maltby, Stephen S. Tobe, and Ian D. Chin-Sang PMCID: PMC2234139 Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons Jens Brodbeck, Maureen E. Balestra, Ann M. Saunders, Allen D. Roses, Robert W. Mahley, and Yadong Huang PMCID: PMC2234140 Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein Laibaik Park, Ping Zhou, Rose Pitstick, Carmen Capone, Josef Anrather, Erin H. Norris, Linda Younkin, Steven Younkin, George Carlson, Bruce S. McEwen, and Costantino Iadecola PMCID: PMC2234141 Action-blindsight in healthy subjects after transcranial magnetic stimulation Mark Schram Christensen, Lasse Kristiansen, James B. Rowe, and Jens Bo Nielsen PMCID: PMC2234142 Pharmacology p21Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus Robert N. Pechnick, Svetlana Zonis, Kolja Wawrowsky, Jonathan Pourmorady, and Vera Chesnokova PMCID: PMC2234143 The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel Aldo A. Rodríguez-Menchaca, Ricardo A. Navarro-Polanco, Tania Ferrer-Villada, Jason Rupp, Frank B. Sachse, Martin Tristani-Firouzi, and José A. Sánchez-Chapula PMCID: PMC2234144 Molecular switch for CLC-K Cl− channel block/activation: Optimal pharmacophoric requirements towards high-affinity ligands Antonella Liantonio, Alessandra Picollo, Giuseppe Carbonara, Giuseppe Fracchiolla, Paolo Tortorella, Fulvio Loiodice, Antonio Laghezza, Elena Babini, Giovanni Zifarelli, Michael Pusch, and Diana Conte Camerino PMCID: PMC2234145 Plant Biology Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells Laurens Pauwels, Kris Morreel, Emilie De Witte, Freya Lammertyn, Marc Van Montagu, Wout Boerjan, Dirk Inzé, and Alain Goossens PMCID: PMC2234147 Corrections Correction for Yu et al., Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure PMCID: PMC2234148 Corrects: Shengqiang Yu, et al. Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure. Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18688–18693. Correction for Zhou et al., The P2 capsid protein of the nonenveloped rice dwarf phytoreovirus induces membrane fusion in insect host cells PMCID: PMC2234149 Corrects: Feng Zhou, et al. The P2 capsid protein of the nonenveloped rice dwarf phytoreovirus induces membrane fusion in insect host cells. Proc Natl Acad Sci U S A. 2007 December 4; 104(49): 19547–19552. |
