| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 November 27; 104(48): 18875–18876. doi: 10.1073/iti4807104.PMCID: PMC2141872 Commentaries Protein anisotropy turns solubility on its head George M. Thurston PMCID: PMC2141873 Controlling elements are wild cards in the epigenomic deck Jennifer E. Cropley and David I. K. Martin PMCID: PMC2141874 PET sheds light on Alzheimer's disease genetic risk Russell H. Swerdlow PMCID: PMC2141875 Profile Profile of Douglas Medin Kaspar Mossman PMCID: PMC2141876 Physical Sciences Applied Physical Sciences Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems Dongeun Huh, Hideki Fujioka, Yi-Chung Tung, Nobuyuki Futai, Robert Paine, III, James B. Grotberg, and Shuichi Takayama PMCID: PMC2141877 Continuous inertial focusing, ordering, and separation of particles in microchannels Dino Di Carlo, Daniel Irimia, Ronald G. Tompkins, and Mehmet Toner PMCID: PMC2141878 Free-surface microfluidic control of surface-enhanced Raman spectroscopy for the optimized detection of airborne molecules Brian D. Piorek, Seung Joon Lee, Juan G. Santiago, Martin Moskovits, Sanjoy Banerjee, and Carl D. Meinhart PMCID: PMC2141879 Breaking the diffraction barrier outside of the optical near-field with bright, collimated light from nanometric apertures Peter R. H. Stark, Allison E. Halleck, and Dale N. Larson PMCID: PMC2141880 Chemistry A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance Katherine E. Augustyn, Edward J. Merino, and Jacqueline K. Barton PMCID: PMC2141881 Kinetics of DNA-mediated docking reactions between vesicles tethered to supported lipid bilayers Yee-Hung M. Chan, Peter Lenz, and Steven G. Boxer PMCID: PMC2141882 Formation of unprecedented actinide  carbon triple bonds in uranium methylidyne molecules Jonathan T. Lyon, Han-Shi Hu, Lester Andrews, and Jun Li PMCID: PMC2141883 From the Cover:
Chemical and archaeological evidence for the earliest cacao beverages John S. Henderson, Rosemary A. Joyce, Gretchen R. Hall, W. Jeffrey Hurst, and Patrick E. McGovern PMCID: PMC2141886 Enzymatic synthesis of a bicyclobutane fatty acid by a hemoprotein–lipoxygenase fusion protein from the cyanobacterium Anabaena PCC 7120 Claus Schneider, Katrin Niisuke, William E. Boeglin, Markus Voehler, Donald F. Stec, Ned A. Porter, and Alan R. Brash PMCID: PMC2141887 Purely stochastic binary decisions in cell signaling models without underlying deterministic bistabilities Maxim N. Artyomov, Jayajit Das, Mehran Kardar, and Arup K. Chakraborty PMCID: PMC2141890 Effect of flexibility and cis residues in single-molecule FRET studies of polyproline Robert B. Best, Kusai A. Merchant, Irina V. Gopich, Benjamin Schuler, Ad Bax, and William A. Eaton PMCID: PMC2141891 Environmental Sciences An atmospheric perspective on North American carbon dioxide exchange: CarbonTracker Wouter Peters, Andrew R. Jacobson, Colm Sweeney, Arlyn E. Andrews, Thomas J. Conway, Kenneth Masarie, John B. Miller, Lori M. P. Bruhwiler, Gabrielle Pétron, Adam I. Hirsch, Douglas E. J. Worthy, Guido R. van der Werf, James T. Randerson, Paul O. Wennberg, Maarten C. Krol, and Pieter P. Tans PMCID: PMC2141884 Geophysics From the Cover:
Pulse-like and crack-like ruptures in experiments mimicking crustal earthquakes Xiao Lu, Nadia Lapusta, and Ares J. Rosakis PMCID: PMC2141885 Biological Sciences Biochemistry A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance Katherine E. Augustyn, Edward J. Merino, and Jacqueline K. Barton PMCID: PMC2141881 Enzymatic synthesis of a bicyclobutane fatty acid by a hemoprotein–lipoxygenase fusion protein from the cyanobacterium Anabaena PCC 7120 Claus Schneider, Katrin Niisuke, William E. Boeglin, Markus Voehler, Donald F. Stec, Ned A. Porter, and Alan R. Brash PMCID: PMC2141887 Molecular architecture of human prion protein amyloid: A parallel, in-register β-structure Nathan J. Cobb, Frank D. Sönnichsen, Hassane Mchaourab, and Witold K. Surewicz PMCID: PMC2141888 Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas Feng Yang, Rena R. Xian, Yingying Li, Tatjana S. Polony, and Karen L. Beemon PMCID: PMC2141889 Biophysics Kinetics of DNA-mediated docking reactions between vesicles tethered to supported lipid bilayers Yee-Hung M. Chan, Peter Lenz, and Steven G. Boxer PMCID: PMC2141882 Purely stochastic binary decisions in cell signaling models without underlying deterministic bistabilities Maxim N. Artyomov, Jayajit Das, Mehran Kardar, and Arup K. Chakraborty PMCID: PMC2141890 Effect of flexibility and cis residues in single-molecule FRET studies of polyproline Robert B. Best, Kusai A. Merchant, Irina V. Gopich, Benjamin Schuler, Ad Bax, and William A. Eaton PMCID: PMC2141891 Combined kinetic and thermodynamic analysis of α-helical membrane protein unfolding Paul Curnow and Paula J. Booth PMCID: PMC2141892 Molecular crowding enhances native structure and stability of α/β protein flavodoxin Loren Stagg, Shao-Qing Zhang, Margaret S. Cheung, and Pernilla Wittung-Stafshede PMCID: PMC2141893 Phenotypic variability of growing cellular populations Ting Lu, Tongye Shen, Matthew R. Bennett, Peter G. Wolynes, and Jeff Hasty PMCID: PMC2141894 Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes Heidi de Wet, Mathew G. Rees, Kenju Shimomura, Jussi Aittoniemi, Ann-Marie Patch, Sarah E. Flanagan, Sian Ellard, Andrew T. Hattersley, Mark S. P. Sansom, and Frances M. Ashcroft PMCID: PMC2141895 The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2 Santiago Ramón-Maiques, Alex J. Kuo, Dylan Carney, Adam G. W. Matthews, Marjorie A. Oettinger, Or Gozani, and Wei Yang PMCID: PMC2141896 X-ray structure of EmrE supports dual topology model Yen-Ju Chen, Owen Pornillos, Samantha Lieu, Che Ma, Andy P. Chen, and Geoffrey Chang PMCID: PMC2141897 Flexibility in the ABC transporter MsbA: Alternating access with a twist Andrew Ward, Christopher L. Reyes, Jodie Yu, Christopher B. Roth, and Geoffrey Chang PMCID: PMC2141898 Cell Biology Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner Shaida Andrabi, Ole V. Gjoerup, Jennifer A. Kean, Thomas M. Roberts, and Brian Schaffhausen PMCID: PMC2141899 In search of an optimal ring to couple microtubule depolymerization to processive chromosome motions Artem Efremov, Ekaterina L. Grishchuk, J. Richard McIntosh, and Fazly I. Ataullakhanov PMCID: PMC2141900 Small molecule regulators of autophagy identified by an image-based high-throughput screen Lihong Zhang, Jia Yu, Heling Pan, Ping Hu, Yan Hao, Wenqing Cai, Hong Zhu, Albert D. Yu, Xin Xie, Dawei Ma, and Junying Yuan PMCID: PMC2141901 Ecology How individual species structure diversity in tropical forests Thorsten Wiegand, C. V. Savitri Gunatilleke, I. A. U. Nimal Gunatilleke, and Andreas Huth PMCID: PMC2141902 Genetics From the Cover:
Genetically regulated epigenetic transcriptional activation of retrotransposon insertion confers mouse dactylaplasia phenotype Hiroki Kano, Hiroki Kurahashi, and Tatsushi Toda PMCID: PMC2141903 Plexin-B1 mutations in prostate cancer Oscar Gee-Wan Wong, Tharani Nitkunan, Izumi Oinuma, Chun Zhou, Veronique Blanc, Richard S. D. Brown, Simon R. J. Bott, Joseph Nariculam, Gary Box, Phillipa Munson, Jason Constantinou, Mark R. Feneley, Helmut Klocker, Suzanne A. Eccles, Manabu Negishi, Alex Freeman, John R. Masters, and Magali Williamson PMCID: PMC2141904 Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans Coleen T. Murphy, Seung-Jae Lee, and Cynthia Kenyon PMCID: PMC2141905 Immunology An action spectrum (290–320 nm) for TNFα protein in human skin in vivo suggests that basal-layer epidermal DNA is the chromophore Susan L. Walker and Antony R. Young PMCID: PMC2141906 Tumor immune escape by the loss of homeostatic chemokine expression Andor Pivarcsi, Anja Müller, Andreas Hippe, Juliane Rieker, Anke van Lierop, Martin Steinhoff, Stephan Seeliger, Robert Kubitza, Ulrich Pippirs, Stephan Meller, Peter A. Gerber, Ruediger Liersch, Erich Buenemann, Eniko Sonkoly, Ulrike Wiesner, Thomas K. Hoffmann, Leonid Schneider, Roland Piekorz, Elaine Enderlein, Julia Reifenberger, Ulrich-Peter Rohr, Rainer Haas, Petra Boukamp, Ingo Haase, Bernd Nürnberg, Thomas Ruzicka, Albert Zlotnik, and Bernhard Homey PMCID: PMC2141907 Vaginal epithelial dendritic cells renew from bone marrow precursors Norifumi Iijima, Melissa M. Linehan, Sem Saeland, and Akiko Iwasaki PMCID: PMC2141908 Medical Sciences From the Cover:
Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism Lisa Mosconi, Miroslaw Brys, Remigiusz Switalski, Rachel Mistur, Lidia Glodzik, Elizabeth Pirraglia, Wai Tsui, Susan De Santi, and Mony J. de Leon PMCID: PMC2141909 A T cell receptor associated with naturally occurring human tumor immunity Bianca D. Santomasso, Wendy K. Roberts, Ashby Thomas, Travis Williams, Nathalie E. Blachère, Mark E. Dudley, Alan N. Houghton, Jerome B. Posner, and Robert B. Darnell PMCID: PMC2141910 Determination of virus burst size in vivo using a single-cycle SIV in rhesus macaques Hannah Yuan Chen, Michele Di Mascio, Alan S. Perelson, David D. Ho, and Linqi Zhang PMCID: PMC2141911 Role of uncoupling protein UCP2 in cell-mediated immunity: How macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes Yalin Emre, Corinne Hurtaud, Melis Karaca, Tobias Nubel, Flora Zavala, and Daniel Ricquier PMCID: PMC2141912 Microbiology Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea Eric J. Nelson, Ashrafuzzaman Chowdhury, Jason B. Harris, Yasmin A. Begum, Fahima Chowdhury, Ashraful I. Khan, Regina C. LaRocque, Anne L. Bishop, Edward T. Ryan, Andrew Camilli, Firdausi Qadri, and Stephen B. Calderwood PMCID: PMC2141913 From the Cover:
Gene family encoding the major toxins of lethal Amanita mushrooms Heather E. Hallen, Hong Luo, John S. Scott-Craig, and Jonathan D. Walton PMCID: PMC2141914 Virus movement maintains local virus population diversity Jamie C. Snyder, Blake Wiedenheft, Matthew Lavin, Francisco F. Roberto, Josh Spuhler, Alice C. Ortmann, Trevor Douglas, and Mark Young PMCID: PMC2141915 Neuroscience Development and regeneration of hair cells share common functional features Snezana Levic, Liping Nie, Dipika Tuteja, Margaret Harvey, Bernd H. A. Sokolowski, and Ebenezer N. Yamoah PMCID: PMC2141916 Neuroglobin attenuates β-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo Adil A. Khan, Xiao Ou Mao, Surita Banwait, Kunlin Jin, and David A. Greenberg PMCID: PMC2141917 Excitatory and suppressive receptive field subunits in awake monkey primary visual cortex (V1) Xiaodong Chen, Feng Han, Mu-ming Poo, and Yang Dan PMCID: PMC2141918 OFF ganglion cells cannot drive the optokinetic reflex in zebrafish Farida Emran, Jason Rihel, Alan R. Adolph, Kwoon Y. Wong, Sebastian Kraves, and John E. Dowling PMCID: PMC2141919 Physiology Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems Dongeun Huh, Hideki Fujioka, Yi-Chung Tung, Nobuyuki Futai, Robert Paine, III, James B. Grotberg, and Shuichi Takayama PMCID: PMC2141877 The digestive adaptation of flying vertebrates: High intestinal paracellular absorption compensates for smaller guts Enrique Caviedes-Vidal, Todd J. McWhorter, Shana R. Lavin, Juan G. Chediack, Christopher R. Tracy, and William H. Karasov PMCID: PMC2141920 Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion Sergio A. Gradilone, Anatoliy I. Masyuk, Patrick L. Splinter, Jesus M. Banales, Bing Q. Huang, Pamela S. Tietz, Tatyana V. Masyuk, and Nicholas F. LaRusso PMCID: PMC2141921 Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury Nathan S. Bryan, John W. Calvert, John W. Elrod, Susheel Gundewar, Sang Yong Ji, and David J. Lefer PMCID: PMC2141922 Plant Biology The transcription factor IDEF1 regulates the response to and tolerance of iron deficiency in plants Takanori Kobayashi, Yuko Ogo, Reiko Nakanishi Itai, Hiromi Nakanishi, Michiko Takahashi, Satoshi Mori, and Naoko K. Nishizawa PMCID: PMC2141923 Psychology Intuitions of probabilities shape expectations about the future at 12 months and beyond Ernő Téglás, Vittorio Girotto, Michel Gonzalez, and Luca L. Bonatti PMCID: PMC2141924 Social Sciences Anthropology From the Cover:
Chemical and archaeological evidence for the earliest cacao beverages John S. Henderson, Rosemary A. Joyce, Gretchen R. Hall, W. Jeffrey Hurst, and Patrick E. McGovern PMCID: PMC2141886 Psychology Intuitions of probabilities shape expectations about the future at 12 months and beyond Ernő Téglás, Vittorio Girotto, Michel Gonzalez, and Luca L. Bonatti PMCID: PMC2141924 Correction Correction for Wu and Feigon, H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification PMCID: PMC2141925 Corrects: Haihong Wu, et al. H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A. 2007 April 17; 104(16): 6655–6660. |
